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The map label for this gene is sdaB [H]

Identifier: 157369872

GI number: 157369872

Start: 1784964

End: 1786331

Strand: Reverse

Name: sdaB [H]

Synonym: Spro_1629

Alternate gene names: 157369872

Gene position: 1786331-1784964 (Counterclockwise)

Preceding gene: 157369873

Following gene: 157369870

Centisome position: 32.78

GC content: 58.11

Gene sequence:

>1368_bases
ATGGTCAGCGTTTTCGATATTTTCAAAATTGGTATTGGCCCATCCAGCTCCCACACCGTCGGCCCGATGAAAGCCGGCAA
GCTGTTTGTCGATGAATTGATTGCCAGCCAGCAGTTGATGGATACCACTCGCGTGGTGGTGGACGTCTACGGTTCGCTGT
CGCTGACCGGCAAAGGTCACCACACCGATATCGCCATTATCATGGGGTTGGCGGGTAACCTGCCGCACGATGTTGATATC
GACGGTATCGCCGGTTTTATCCGCGACGTTGAACAACGCGGCCGCCTGTTGCTGGCCAAGGGCCACCACGAAGTGGATTT
CCCGCTGCAAACCAGCATGAATTTCAACAGCGATAATTTACCGCTGCACGAAAACGGCATGCGCATCAGCGCCTTCGCCG
GTGAACAACTGTTACACAGCAAAACCTATTACTCTACCGGCGGCGGTTTTATCGTCGATGAAGAAAACTTCGGCCTGGCT
GCGGCCAATCCGGTTCAGGTCCCCTTCCCGTTCAACTCGGCGCGAGACTTGCAGCAACACTGTAAAGACGCCGGTTTGTC
GCTATCCGGCCTGGTGATGCAAAACGAATTGGCGCTGCACAGCAAGGCCGAGATCGACGCGCACTTCGCCGACGTCTGGC
AGGTGATGCGCGCCGGCATCGAACGCGGTATGAACACCGAAGGTCTGTTGCCCGGCCCGATGAAAGTTCAACGCCGCGCT
GCCGCCCTGCGCCGCCTGCTGGTGACCGGTGACAAGAACAATATCGATCCGATGAACGTGGTCGACTGGATCAACATGTT
CGCCTTTGCCGTTAACGAAGAAAATGCTGCCGGTGGCCGTGTGGTCACCGCCCCGACCAACGGCGCCTGTGGCATCATCC
CGGCGGTGCTGGCCTATTACGACCAGTTTATTCGCCCGGTAAACCCCAATTCCTACAGCCGTTATTTCCTGACGTCCGGT
GTGATCGGTGCGCTGTACAAAATGAACGCTTCAATCTCCGGTGCCGAAGTGGGCTGTCAGGGCGAGGTGGGCGTCGCCTG
CTCAATGGCCGCAGCAGGGTTGGCAGAATTGATGGGCGGCAGCCCGGCACAGGTTTGTATCGCGGCGGAGATCGCCATGG
AGCACCACCTGGGGCTAACCTGCGATCCGCTGGCCGGTCAGGTTCAGGTACCCTGTATCGAACGTAACGCGATTTCCGCG
GTGAAGGCGGTCAATGCCGCACGTATGGCGCTGCGCCGCACCAGTGAGCCGCGCGTGTGCCTGGATAAGGTGATCGAAAC
CATGTATGAGACGGGCAAAGACATGAACGCCAAGTACCGCGAGACATCGCAAGGGGGATTGGCGATCAAGGTAGTGGCCT
GTAACTGA

Upstream 100 bases:

>100_bases
AGCTTCTAATCAAGCCCAGCCGGCGCTACCTTGCGCCGGCTTTTCAGCACGGCCCCCTTTCCTGCATTAACGCCTAACAC
CTGAAGAAGGAGGCGAGACC

Downstream 100 bases:

>100_bases
TAAAAAAAGAGGGCGCAATCATCAATGACGGCGCCCTCTTCTTAAAGCTTATTGCTGTAACCCTTAACCAAACACGCTAC
CGAACCACTGGGTCAGCTTC

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH 2; L-serine deaminase 2; L-SD2 [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MVSVFDIFKIGIGPSSSHTVGPMKAGKLFVDELIASQQLMDTTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPHDVDI
DGIAGFIRDVEQRGRLLLAKGHHEVDFPLQTSMNFNSDNLPLHENGMRISAFAGEQLLHSKTYYSTGGGFIVDEENFGLA
AANPVQVPFPFNSARDLQQHCKDAGLSLSGLVMQNELALHSKAEIDAHFADVWQVMRAGIERGMNTEGLLPGPMKVQRRA
AALRRLLVTGDKNNIDPMNVVDWINMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDQFIRPVNPNSYSRYFLTSG
VIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELMGGSPAQVCIAAEIAMEHHLGLTCDPLAGQVQVPCIERNAISA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSQGGLAIKVVACN

Sequences:

>Translated_455_residues
MVSVFDIFKIGIGPSSSHTVGPMKAGKLFVDELIASQQLMDTTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPHDVDI
DGIAGFIRDVEQRGRLLLAKGHHEVDFPLQTSMNFNSDNLPLHENGMRISAFAGEQLLHSKTYYSTGGGFIVDEENFGLA
AANPVQVPFPFNSARDLQQHCKDAGLSLSGLVMQNELALHSKAEIDAHFADVWQVMRAGIERGMNTEGLLPGPMKVQRRA
AALRRLLVTGDKNNIDPMNVVDWINMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDQFIRPVNPNSYSRYFLTSG
VIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELMGGSPAQVCIAAEIAMEHHLGLTCDPLAGQVQVPCIERNAISA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSQGGLAIKVVACN
>Mature_455_residues
MVSVFDIFKIGIGPSSSHTVGPMKAGKLFVDELIASQQLMDTTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPHDVDI
DGIAGFIRDVEQRGRLLLAKGHHEVDFPLQTSMNFNSDNLPLHENGMRISAFAGEQLLHSKTYYSTGGGFIVDEENFGLA
AANPVQVPFPFNSARDLQQHCKDAGLSLSGLVMQNELALHSKAEIDAHFADVWQVMRAGIERGMNTEGLLPGPMKVQRRA
AALRRLLVTGDKNNIDPMNVVDWINMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDQFIRPVNPNSYSRYFLTSG
VIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELMGGSPAQVCIAAEIAMEHHLGLTCDPLAGQVQVPCIERNAISA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSQGGLAIKVVACN

Specific function: Deaminates also threonine, particularly when it is present in high concentration [H]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=455, Percent_Identity=78.4615384615385, Blast_Score=758, Evalue=0.0,
Organism=Escherichia coli, GI1788116, Length=451, Percent_Identity=76.7184035476718, Blast_Score=729, Evalue=0.0,
Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=73.4513274336283, Blast_Score=674, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48732; Mature: 48732

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVFDIFKIGIGPSSSHTVGPMKAGKLFVDELIASQQLMDTTRVVVDVYGSLSLTGKGH
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCC
HTDIAIIMGLAGNLPHDVDIDGIAGFIRDVEQRGRLLLAKGHHEVDFPLQTSMNFNSDNL
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCCCCCC
PLHENGMRISAFAGEQLLHSKTYYSTGGGFIVDEENFGLAAANPVQVPFPFNSARDLQQH
CCCCCCCEEEEECCHHHHHCCCEEECCCCEEEECCCCCEEECCCEEECCCCCCHHHHHHH
CKDAGLSLSGLVMQNELALHSKAEIDAHFADVWQVMRAGIERGMNTEGLLPGPMKVQRRA
HHHHCCCEEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AALRRLLVTGDKNNIDPMNVVDWINMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DQFIRPVNPNSYSRYFLTSGVIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELMGG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHHLGLTCDPLAGQVQVPCIERNAISAVKAVNAARMALRRTSEPRVC
CCHHEEEHHHHHHHHCCCCEECCCCCCEECCEECCHHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSQGGLAIKVVACN
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure
MVSVFDIFKIGIGPSSSHTVGPMKAGKLFVDELIASQQLMDTTRVVVDVYGSLSLTGKGH
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEECCCCC
HTDIAIIMGLAGNLPHDVDIDGIAGFIRDVEQRGRLLLAKGHHEVDFPLQTSMNFNSDNL
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCEECCCCCCCCCC
PLHENGMRISAFAGEQLLHSKTYYSTGGGFIVDEENFGLAAANPVQVPFPFNSARDLQQH
CCCCCCCEEEEECCHHHHHCCCEEECCCCEEEECCCCCEEECCCEEECCCCCCHHHHHHH
CKDAGLSLSGLVMQNELALHSKAEIDAHFADVWQVMRAGIERGMNTEGLLPGPMKVQRRA
HHHHCCCEEEEEEECHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AALRRLLVTGDKNNIDPMNVVDWINMFAFAVNEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DQFIRPVNPNSYSRYFLTSGVIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELMGG
HHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHHLGLTCDPLAGQVQVPCIERNAISAVKAVNAARMALRRTSEPRVC
CCHHEEEHHHHHHHHCCCCEECCCCCCEECCEECCHHHHHHHHHHHHHHHHHCCCCCHHH
LDKVIETMYETGKDMNAKYRETSQGGLAIKVVACN
HHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8385012; 9278503 [H]