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The map label for this gene is crl

Identifier: 157369211

GI number: 157369211

Start: 1064311

End: 1064712

Strand: Direct

Name: crl

Synonym: Spro_0966

Alternate gene names: 157369211

Gene position: 1064311-1064712 (Clockwise)

Preceding gene: 157369210

Following gene: 157369212

Centisome position: 19.53

GC content: 49.25

Gene sequence:

>402_bases
ATGACGTTACCGAGTGGTCACCCTAAAAGCCGACTAATGAAACGTTTCGCCAGCTTGGGGCCGTATCTGCGTGAAGGGCA
ATGTGAGAACGACCGTTTTTTCTTTGATTGTTTAGCCGTCTGCGTCAATGTTAAGCCTGCTCCAGAGCTGCGAGAGTTTT
GGGGTTGGTGGATCGAACTGCATGCTGAAGATACGCGTTTTACCTATTCGTATCAGTTTGGCCTGTTTGATAAGAAAGGG
CAGTGGACGCCGGAAAAGATTAAGGATACTGAAGTCAAAACCAAGCTGGAAACCACCCTGCGTGATTTCCATCGTCGTCT
GGGCGAACTGCTGGCCACCATGGAGCTGACGCTTGAACCCGCCGCTGATTTCAAAGAAAAACTGATTAAACTTTCCGCCT
GA

Upstream 100 bases:

>100_bases
TGCTGCAAATGTCCCATTGGATGAAAGATAAAATGCGTTAATTAGTTGCTAAATTTTAACAGTTTGTTAAAAAGAATGGT
CTACATTGAGGAGCTTAAGA

Downstream 100 bases:

>100_bases
CCCCGTTTGACCGCAAGTATTCTGCTGATTTCGCGTTGTGCCTGTTGGCATAACGCGTCTCTCCTGTTACAAAGTCCCTA
GTATTATTCTTCTCATCTTA

Product: DNA-binding transcriptional regulator Crl

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTLPSGHPKSRLMKRFASLGPYLREGQCENDRFFFDCLAVCVNVKPAPELREFWGWWIELHAEDTRFTYSYQFGLFDKKG
QWTPEKIKDTEVKTKLETTLRDFHRRLGELLATMELTLEPAADFKEKLIKLSA

Sequences:

>Translated_133_residues
MTLPSGHPKSRLMKRFASLGPYLREGQCENDRFFFDCLAVCVNVKPAPELREFWGWWIELHAEDTRFTYSYQFGLFDKKG
QWTPEKIKDTEVKTKLETTLRDFHRRLGELLATMELTLEPAADFKEKLIKLSA
>Mature_132_residues
TLPSGHPKSRLMKRFASLGPYLREGQCENDRFFFDCLAVCVNVKPAPELREFWGWWIELHAEDTRFTYSYQFGLFDKKGQ
WTPEKIKDTEVKTKLETTLRDFHRRLGELLATMELTLEPAADFKEKLIKLSA

Specific function: Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the crl family

Homologues:

Organism=Escherichia coli, GI1786435, Length=133, Percent_Identity=69.1729323308271, Blast_Score=206, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CRL_SERP5 (A8GAD2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477200.1
- STRING:   A8GAD2
- GeneID:   5603744
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0966
- eggNOG:   NOG06255
- HOGENOM:   HBG644153
- OMA:   PYIREEQ
- ProtClustDB:   PRK10984
- BioCyc:   SPRO399741:SPRO_0966-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01178
- InterPro:   IPR009986

Pfam domain/function: PF07417 Crl

EC number: NA

Molecular weight: Translated: 15633; Mature: 15502

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPSGHPKSRLMKRFASLGPYLREGQCENDRFFFDCLAVCVNVKPAPELREFWGWWIEL
CCCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEE
HAEDTRFTYSYQFGLFDKKGQWTPEKIKDTEVKTKLETTLRDFHRRLGELLATMELTLEP
EECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AADFKEKLIKLSA
HHHHHHHHHHCCC
>Mature Secondary Structure 
TLPSGHPKSRLMKRFASLGPYLREGQCENDRFFFDCLAVCVNVKPAPELREFWGWWIEL
CCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHEEEE
HAEDTRFTYSYQFGLFDKKGQWTPEKIKDTEVKTKLETTLRDFHRRLGELLATMELTLEP
EECCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AADFKEKLIKLSA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA