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The map label for this gene is mtnB [H]

Identifier: 157369187

GI number: 157369187

Start: 1040588

End: 1041208

Strand: Direct

Name: mtnB [H]

Synonym: Spro_0942

Alternate gene names: 157369187

Gene position: 1040588-1041208 (Clockwise)

Preceding gene: 157369184

Following gene: 157369188

Centisome position: 19.1

GC content: 56.2

Gene sequence:

>621_bases
ATGTTAATGACAGAAAATCAGCAACTTAAAGCGTTATTGTCGGCCTGTCACTGGATTGGTGAAAAGGGCTGGTGCCCGGC
GACCGGTGGCAATATGTCGCTGCGTCTCGATGACCAACATTGTCTGGTCACCGAATCCGGCAAGGATAAGGGCAGCCTGA
CTGAAACTGACTTCCTGCTGGTGGAAACCGCCAGCAACCATGTGCCGAGCGGCCGCACGCCATCAGCGGAAACCGGTCTG
CATACCCTTATTTACCGTTTGTACCCGCAGATTGGCGCGGTACTGCATACTCATTCGGTGAATGCGACCGTGCTGTCGCG
GGTTGAACGCAGCGATGGGCTGGTGTTGCAGGGCTATGAGATGCAAAAATCACTCGGTGGGCAGACTACGCATCTGGACA
GCGTGGTGATCCCGATTTTCGATAACGATCAGGATATCTCGCGATTAGCGGCGCGGGTGGCAGCCCATGCCGAAGCCACG
CCGTTGCAGTACGGTTTTCTGGTGCGTGGCCACGGTCTGTATTGCTGGGGTCGCCAGGTCGCGGAAGCTCGTCGTCATCT
TGAAGGGCTGGAATTCCTGTTCCAGTGCGAACTGCAACGCCGTTTACTGGAGGCCAAATGA

Upstream 100 bases:

>100_bases
ATTTGGCAATCAAGACGCTTAGATGGCTAAATGAAGAAAAAGTCTTGCCCTTAATCAAATCATTCTAGACATCATTTGCT
TATAACCTACAGGTCAAAAA

Downstream 100 bases:

>100_bases
TCCGCGCCATCGTTACCGACATTGAAGGTACCACCAGCGATATCCGTTTCGTTCATCAGGTGCTGTTCCCTTACGCACGT
GAACGCCTGGCCACCTTTCT

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMTENQQLKALLSACHWIGEKGWCPATGGNMSLRLDDQHCLVTESGKDKGSLTETDFLLVETASNHVPSGRTPSAETGL
HTLIYRLYPQIGAVLHTHSVNATVLSRVERSDGLVLQGYEMQKSLGGQTTHLDSVVIPIFDNDQDISRLAARVAAHAEAT
PLQYGFLVRGHGLYCWGRQVAEARRHLEGLEFLFQCELQRRLLEAK

Sequences:

>Translated_206_residues
MLMTENQQLKALLSACHWIGEKGWCPATGGNMSLRLDDQHCLVTESGKDKGSLTETDFLLVETASNHVPSGRTPSAETGL
HTLIYRLYPQIGAVLHTHSVNATVLSRVERSDGLVLQGYEMQKSLGGQTTHLDSVVIPIFDNDQDISRLAARVAAHAEAT
PLQYGFLVRGHGLYCWGRQVAEARRHLEGLEFLFQCELQRRLLEAK
>Mature_206_residues
MLMTENQQLKALLSACHWIGEKGWCPATGGNMSLRLDDQHCLVTESGKDKGSLTETDFLLVETASNHVPSGRTPSAETGL
HTLIYRLYPQIGAVLHTHSVNATVLSRVERSDGLVLQGYEMQKSLGGQTTHLDSVVIPIFDNDQDISRLAARVAAHAEAT
PLQYGFLVRGHGLYCWGRQVAEARRHLEGLEFLFQCELQRRLLEAK

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily [H]

Homologues:

Organism=Homo sapiens, GI166235186, Length=183, Percent_Identity=28.9617486338798, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI18859685, Length=198, Percent_Identity=26.7676767676768, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR017714 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.2.1.109 [H]

Molecular weight: Translated: 22835; Mature: 22835

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMTENQQLKALLSACHWIGEKGWCPATGGNMSLRLDDQHCLVTESGKDKGSLTETDFLL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEE
VETASNHVPSGRTPSAETGLHTLIYRLYPQIGAVLHTHSVNATVLSRVERSDGLVLQGYE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCH
MQKSLGGQTTHLDSVVIPIFDNDQDISRLAARVAAHAEATPLQYGFLVRGHGLYCWGRQV
HHHHCCCCCEECCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHH
AEARRHLEGLEFLFQCELQRRLLEAK
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLMTENQQLKALLSACHWIGEKGWCPATGGNMSLRLDDQHCLVTESGKDKGSLTETDFLL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCCEEEE
VETASNHVPSGRTPSAETGLHTLIYRLYPQIGAVLHTHSVNATVLSRVERSDGLVLQGYE
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCH
MQKSLGGQTTHLDSVVIPIFDNDQDISRLAARVAAHAEATPLQYGFLVRGHGLYCWGRQV
HHHHCCCCCEECCEEEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEHHHHH
AEARRHLEGLEFLFQCELQRRLLEAK
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA