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The map label for this gene is yedX [C]

Identifier: 157369184

GI number: 157369184

Start: 1038131

End: 1038466

Strand: Direct

Name: yedX [C]

Synonym: Spro_0939

Alternate gene names: 157369184

Gene position: 1038131-1038466 (Clockwise)

Preceding gene: 157369183

Following gene: 157369187

Centisome position: 19.05

GC content: 56.55

Gene sequence:

>336_bases
ATGAGTAATATCAGCACCCATATTCTGGACACCTCACTCGGTAAACCCGCTGCGGGCGTGCGGGTGTGGTTGGAACACGA
ACAGGACGGGTTATGGCGAACCCTGGCAGAAAGCCAGACCGATGCTGACGGCCGCGCGCGTGATCTAACCTCTGACAGTC
TGCTTGCCGGACATTACCGCCTGTCTGCCGATCTCGGCGCTTACTTTTCCCGTGACCTGCGTGAAACGCTGTACGCCACG
GCAATTATCGATTTCGTCATTCAGGATGCGGCGCAGCATTACCATTTACCGCTGCTCATCAGCCCATATTCCTACTCGAC
CTACCGGGGCAGTTAG

Upstream 100 bases:

>100_bases
TTGCAACGGCGATTGAATAACAGTGCGGAACAGGAACGGCGGGAAACGGCGGAACAACTGCGTGAAATCACGATGCTGCG
TTTTAAGGAGCTACTGAGCG

Downstream 100 bases:

>100_bases
ACGCTCGTCTGAAGTTACGGGTGCAGCGAACCGCACCCGCAATGATTAATCGTGGCGCAGGAAGCTGTCGGCATCACGCC
AGGCCGGGAAGGCGCTGCGG

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MSNISTHILDTSLGKPAAGVRVWLEHEQDGLWRTLAESQTDADGRARDLTSDSLLAGHYRLSADLGAYFSRDLRETLYAT
AIIDFVIQDAAQHYHLPLLISPYSYSTYRGS

Sequences:

>Translated_111_residues
MSNISTHILDTSLGKPAAGVRVWLEHEQDGLWRTLAESQTDADGRARDLTSDSLLAGHYRLSADLGAYFSRDLRETLYAT
AIIDFVIQDAAQHYHLPLLISPYSYSTYRGS
>Mature_110_residues
SNISTHILDTSLGKPAAGVRVWLEHEQDGLWRTLAESQTDADGRARDLTSDSLLAGHYRLSADLGAYFSRDLRETLYATA
IIDFVIQDAAQHYHLPLLISPYSYSTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=109, Percent_Identity=42.2018348623853, Blast_Score=91, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115532922, Length=111, Percent_Identity=39.6396396396396, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532920, Length=111, Percent_Identity=39.6396396396396, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115534555, Length=111, Percent_Identity=36.9369369369369, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24652571, Length=111, Percent_Identity=45.045045045045, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12387; Mature: 12256

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00768 TRANSTHYRETIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNISTHILDTSLGKPAAGVRVWLEHEQDGLWRTLAESQTDADGRARDLTSDSLLAGHYR
CCCCCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCEE
LSADLGAYFSRDLRETLYATAIIDFVIQDAAQHYHLPLLISPYSYSTYRGS
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
SNISTHILDTSLGKPAAGVRVWLEHEQDGLWRTLAESQTDADGRARDLTSDSLLAGHYR
CCCCCCEEECCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCEEECCEE
LSADLGAYFSRDLRETLYATAIIDFVIQDAAQHYHLPLLISPYSYSTYRGS
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]