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The map label for this gene is murG

Identifier: 157369006

GI number: 157369006

Start: 849587

End: 850651

Strand: Direct

Name: murG

Synonym: Spro_0761

Alternate gene names: 157369006

Gene position: 849587-850651 (Clockwise)

Preceding gene: 157369005

Following gene: 157369007

Centisome position: 15.59

GC content: 60.19

Gene sequence:

>1065_bases
ATGAGCGGGAAACCTAAGCGTTTAATGGTGATGGCAGGCGGTACCGGCGGACACGTGTTCCCGGGACTGGCGGTCGCACA
TCATCTGATGGCGCAGGGCTGGCAGGTGCGCTGGCTCGGAACCGCAGACCGAATGGAAGCCGATTTGGTGCCAAAGCACG
GGATCGAAATTGATTTCATCCGTATTTCTGGCCTGCGCGGTAAAGGGCTGAAGGCCCAGTTGAGCGCACCGCTGCGTATC
TGGCACGCGGTACGTCAGGCGAAGGCGATCATGCGCAACTACCAGCCGGACGTGGTGCTGGGCATGGGCGGTTATGTTTC
CGGCCCTGGCGGTTTGGCGGCATGGTTGTGCGGTATCCCGGTGGTATTGCACGAGCAAAACGGTATTGCCGGGCTGACCA
ACCGTTGGTTGGCGCGTATTGCCAAAACCGTGCTGCAGGCATTTCCTGGTGCGTTCCCGAACGCCGAGGTGGTGGGCAAC
CCGGTCCGTACCGACGTACTGGCGTTACCGCTACCGGCAGAACGTTTGATTGGCCGTGAAGGGCCGATCCGCGTGTTGGT
GATTGGCGGCAGTCAGGGGGCACGGGTGCTGAATCAGACAGTTCCTGAAGTCGCGGCGAGATTGGGCGATAAAATAACGC
TCTGGCATCAGGTAGGTAAAGGTGCACTGGAAAACGTGTTGCGCGACTACGAGAGGGTAGGGCAGACGCAGCACAAGGTG
GCCGAGTTTATTGATGACATGGCTGCCGCCTACGCCTGGGCTGATGTGGTGGTGTGCCGTTCCGGCGCGTTGACCGTCAG
CGAGATTGCTGCCGCAGGCCTGCCCGCGATATTCGTGCCATTCCAGCACAAAGACCGTCAGCAATATTGGAATGCTCGTC
CGCTGGAAGAAGCCGGCGCGGCGAAGATTATCGAACAACCGCAGTTTAACGCCGATGTAGTGGCGGAACTGCTGGCTGGC
TGGGATCGTCCAACGCTGTTGGCAATGGCTGAAAAGGCGCGCGCTGTCGCCATTCCGGATGCTACCGAGCGTGTGGCGGC
GGAGTTGGTGCGGGTCGCCAAATAA

Upstream 100 bases:

>100_bases
CTCGAGCCTGCTGATTATGTCGACGGCGATCGTGCTGTTACTGCGTATTGATTATGAAACGCGTCTGGCTAAAGCCCAGG
CGTTTGTGAAGAGGTAAGGG

Downstream 100 bases:

>100_bases
TTTGCAGGGGTTCGGTACGCCGGGCCTGAATTAAAGAATGTCATACAGGGGCCCGGTATGCCGGACCCGGATTAGAGAGA
GTGATGAATACACAACAACT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSGKPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGLKAQLSAPLRI
WHAVRQAKAIMRNYQPDVVLGMGGYVSGPGGLAAWLCGIPVVLHEQNGIAGLTNRWLARIAKTVLQAFPGAFPNAEVVGN
PVRTDVLALPLPAERLIGREGPIRVLVIGGSQGARVLNQTVPEVAARLGDKITLWHQVGKGALENVLRDYERVGQTQHKV
AEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNARPLEEAGAAKIIEQPQFNADVVAELLAG
WDRPTLLAMAEKARAVAIPDATERVAAELVRVAK

Sequences:

>Translated_354_residues
MSGKPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGLKAQLSAPLRI
WHAVRQAKAIMRNYQPDVVLGMGGYVSGPGGLAAWLCGIPVVLHEQNGIAGLTNRWLARIAKTVLQAFPGAFPNAEVVGN
PVRTDVLALPLPAERLIGREGPIRVLVIGGSQGARVLNQTVPEVAARLGDKITLWHQVGKGALENVLRDYERVGQTQHKV
AEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNARPLEEAGAAKIIEQPQFNADVVAELLAG
WDRPTLLAMAEKARAVAIPDATERVAAELVRVAK
>Mature_353_residues
SGKPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGLKAQLSAPLRIW
HAVRQAKAIMRNYQPDVVLGMGGYVSGPGGLAAWLCGIPVVLHEQNGIAGLTNRWLARIAKTVLQAFPGAFPNAEVVGNP
VRTDVLALPLPAERLIGREGPIRVLVIGGSQGARVLNQTVPEVAARLGDKITLWHQVGKGALENVLRDYERVGQTQHKVA
EFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNARPLEEAGAAKIIEQPQFNADVVAELLAGW
DRPTLLAMAEKARAVAIPDATERVAAELVRVAK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=354, Percent_Identity=81.9209039548023, Blast_Score=598, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SERP5 (A8G9S7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476995.1
- ProteinModelPortal:   A8G9S7
- SMR:   A8G9S7
- STRING:   A8G9S7
- GeneID:   5604638
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0761
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- ProtClustDB:   PRK00726
- BioCyc:   SPRO399741:SPRO_0761-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38129; Mature: 37998

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGKPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFI
CCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEE
RISGLRGKGLKAQLSAPLRIWHAVRQAKAIMRNYQPDVVLGMGGYVSGPGGLAAWLCGIP
EEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCC
VVLHEQNGIAGLTNRWLARIAKTVLQAFPGAFPNAEVVGNPVRTDVLALPLPAERLIGRE
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHCEEECCCCHHHHCCCC
GPIRVLVIGGSQGARVLNQTVPEVAARLGDKITLWHQVGKGALENVLRDYERVGQTQHKV
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHHHHCHHHHHH
AEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNARPLEEAGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCHHHHCCCCCCHHHCH
AKIIEQPQFNADVVAELLAGWDRPTLLAMAEKARAVAIPDATERVAAELVRVAK
HHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGKPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFI
CCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCCCCEEEEE
RISGLRGKGLKAQLSAPLRIWHAVRQAKAIMRNYQPDVVLGMGGYVSGPGGLAAWLCGIP
EEECCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCC
VVLHEQNGIAGLTNRWLARIAKTVLQAFPGAFPNAEVVGNPVRTDVLALPLPAERLIGRE
EEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCHHHCEEECCCCHHHHCCCC
GPIRVLVIGGSQGARVLNQTVPEVAARLGDKITLWHQVGKGALENVLRDYERVGQTQHKV
CCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEHHHHCHHHHHHHHHHHHHHCHHHHHH
AEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNARPLEEAGA
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEEECCCCCCHHHHCCCCCCHHHCH
AKIIEQPQFNADVVAELLAGWDRPTLLAMAEKARAVAIPDATERVAAELVRVAK
HHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA