Click here to switch to the map view.

The map label for this gene is ftsW [H]

Identifier: 157369005

GI number: 157369005

Start: 848381

End: 849583

Strand: Direct

Name: ftsW [H]

Synonym: Spro_0760

Alternate gene names: 157369005

Gene position: 848381-849583 (Clockwise)

Preceding gene: 157369004

Following gene: 157369006

Centisome position: 15.57

GC content: 55.69

Gene sequence:

>1203_bases
ATGAGACTACGCTTGCCGAACTTCGGGTTGACCGAACTGTTTAAAAACTGGGTCGCGGGATCGCGTGATAACGACTCGGT
CAATATGGTGTTGTACGATCGCACCTTACTGTGGCTGACCTTTGGGTTGGCCATTATCGGTTTTGTGATGGTGACCTCGG
CATCGATGCCGATCGGTCAGCGTCTGGCGGACGATCCTTTCCTGTTCGCCAAGCGTGATGCGCTGTACCTCGCCTTGGCG
TTCGGCCTGTCGATGGTGACGCTGCGCATTCCGATGGAAGTCTGGCAGCGCTACAGCAACATCATGCTGCTGTTGTCGAT
TGTGATGCTGTTGATCGTATTGGTGGTCGGCAGCTCGGTAAACGGGGCATCACGCTGGATCTCGCTGGGGCCGCTGCGTA
TTCAGCCGGCAGAGTTGTCCAAGCTGTCGCTGTTCTGTTACCTGGCAAGTTATCTGGTGCGCAAGGTAGAAGAAGTGCGT
ACCAACTTTTGGGGCTTCTGCAAGCCGATGGGCGTGATGGTGGTGCTGGCGGTATTGCTGCTGGCCCAGCCGGATCTGGG
TACCGTGGTCGTGCTGTTCATTACCACGCTGGCGATGCTGTTCCTGGCCGGTGCCAAAATGTGGCAGTTCCTGGCGATTA
TCGGCTCCGGAGCTTTCGCGGTGGTGCTGTTGATCATTGCCGAACCTTACCGTATGCGCCGCGTGACGTCGTTCTGGAAT
CCATGGGCCGATCCGTTCGGCAGCGGCTACCAGTTGACCCAGTCGCTGATGGCCTTTGGACGCGGTGAGTTCTGGGGACA
GGGGTTGGGGAACTCGGTACAGAAACTCGAGTATTTACCGGAAGCGCACACCGACTTTATCTTCTCGATTTTAGGCGAAG
AACTGGGCTATATCGGTGTGGTTTTTGCATTGTTAATGGTATTCTGCGTCGCTTTTCGTGCTATGTCGATTGGCCGCCGT
GCGCTGGAGCTGGATCAACGTTTTTCCGGCTTTTTGGCCTGCTCAATTGGCGTGTGGTTTAGCTTCCAGGCGTTGGTTAA
CGTCGGTGCGGCGGCAGGTATGTTGCCGACCAAAGGTCTGACGCTGCCATTGATAAGCTACGGCGGCTCGAGCCTGCTGA
TTATGTCGACGGCGATCGTGCTGTTACTGCGTATTGATTATGAAACGCGTCTGGCTAAAGCCCAGGCGTTTGTGAAGAGG
TAA

Upstream 100 bases:

>100_bases
ATATGGTGTTGCTGTCACCGGCATGCGCCAGCCTGGACCAGTTCCGTAATTTTGAAGTGCGCGGCGACGAGTTCGCCCGT
CTGGCACAGGAGCTCGGCGG

Downstream 100 bases:

>100_bases
GGGATGAGCGGGAAACCTAAGCGTTTAATGGTGATGGCAGGCGGTACCGGCGGACACGTGTTCCCGGGACTGGCGGTCGC
ACATCATCTGATGGCGCAGG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MRLRLPNFGLTELFKNWVAGSRDNDSVNMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLADDPFLFAKRDALYLALA
FGLSMVTLRIPMEVWQRYSNIMLLLSIVMLLIVLVVGSSVNGASRWISLGPLRIQPAELSKLSLFCYLASYLVRKVEEVR
TNFWGFCKPMGVMVVLAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFLAIIGSGAFAVVLLIIAEPYRMRRVTSFWN
PWADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYIGVVFALLMVFCVAFRAMSIGRR
ALELDQRFSGFLACSIGVWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIVLLLRIDYETRLAKAQAFVKR

Sequences:

>Translated_400_residues
MRLRLPNFGLTELFKNWVAGSRDNDSVNMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLADDPFLFAKRDALYLALA
FGLSMVTLRIPMEVWQRYSNIMLLLSIVMLLIVLVVGSSVNGASRWISLGPLRIQPAELSKLSLFCYLASYLVRKVEEVR
TNFWGFCKPMGVMVVLAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFLAIIGSGAFAVVLLIIAEPYRMRRVTSFWN
PWADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYIGVVFALLMVFCVAFRAMSIGRR
ALELDQRFSGFLACSIGVWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIVLLLRIDYETRLAKAQAFVKR
>Mature_400_residues
MRLRLPNFGLTELFKNWVAGSRDNDSVNMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQRLADDPFLFAKRDALYLALA
FGLSMVTLRIPMEVWQRYSNIMLLLSIVMLLIVLVVGSSVNGASRWISLGPLRIQPAELSKLSLFCYLASYLVRKVEEVR
TNFWGFCKPMGVMVVLAVLLLAQPDLGTVVVLFITTLAMLFLAGAKMWQFLAIIGSGAFAVVLLIIAEPYRMRRVTSFWN
PWADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYIGVVFALLMVFCVAFRAMSIGRR
ALELDQRFSGFLACSIGVWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIVLLLRIDYETRLAKAQAFVKR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=400, Percent_Identity=80.25, Blast_Score=637, Evalue=0.0,
Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=31.5315315315315, Blast_Score=153, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44377; Mature: 44377

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRLPNFGLTELFKNWVAGSRDNDSVNMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQ
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RLADDPFLFAKRDALYLALAFGLSMVTLRIPMEVWQRYSNIMLLLSIVMLLIVLVVGSSV
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGASRWISLGPLRIQPAELSKLSLFCYLASYLVRKVEEVRTNFWGFCKPMGVMVVLAVLL
CCHHHHEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQPDLGTVVVLFITTLAMLFLAGAKMWQFLAIIGSGAFAVVLLIIAEPYRMRRVTSFWN
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHC
PWADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYIGV
CCCCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VFALLMVFCVAFRAMSIGRRALELDQRFSGFLACSIGVWFSFQALVNVGAAAGMLPTKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TLPLISYGGSSLLIMSTAIVLLLRIDYETRLAKAQAFVKR
CEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLRLPNFGLTELFKNWVAGSRDNDSVNMVLYDRTLLWLTFGLAIIGFVMVTSASMPIGQ
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHH
RLADDPFLFAKRDALYLALAFGLSMVTLRIPMEVWQRYSNIMLLLSIVMLLIVLVVGSSV
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NGASRWISLGPLRIQPAELSKLSLFCYLASYLVRKVEEVRTNFWGFCKPMGVMVVLAVLL
CCHHHHEEECCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAQPDLGTVVVLFITTLAMLFLAGAKMWQFLAIIGSGAFAVVLLIIAEPYRMRRVTSFWN
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHC
PWADPFGSGYQLTQSLMAFGRGEFWGQGLGNSVQKLEYLPEAHTDFIFSILGEELGYIGV
CCCCCCCCHHHHHHHHHHHCCCCHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VFALLMVFCVAFRAMSIGRRALELDQRFSGFLACSIGVWFSFQALVNVGAAAGMLPTKGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TLPLISYGGSSLLIMSTAIVLLLRIDYETRLAKAQAFVKR
CEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]