| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is murE [H]
Identifier: 157369001
GI number: 157369001
Start: 843141
End: 844628
Strand: Direct
Name: murE [H]
Synonym: Spro_0756
Alternate gene names: 157369001
Gene position: 843141-844628 (Clockwise)
Preceding gene: 157369000
Following gene: 157369002
Centisome position: 15.47
GC content: 60.55
Gene sequence:
>1488_bases GTGGCCGATCGTAATTTGCGCGACTTACTCGCTCCGTGGGTGCCAACGGCGCCCGGGCGCGCGCTGCGGGAAATGACATT AGACAGCCGTATTGCGGCTGCCGGGGATCTGTTTGTCGCCGTTGTTGGCCATCAGGCAGATGGACGCCGCTTTATTCCGC AGGCTATCGCGCAGGGCGTTGCCGCTGTGATTGCCGAAGCTGAAGGCCAGGCTGAAGACGGTGCTATTACTGAAATGCAC GGCGTGCCGGTGATTTATCTGAGCCAGCTTAATCAGCGCCTTTCCGCGTTGGCCGGTCGTTTTTACCATGAGCCGGCAGA GCGTCTGCGTTTGGTCGGCGTCACCGGGACCAACGGCAAGACCACCACCACTCAACTGCTGGCACAGTGGGGCCAACTGC TGGGTGAAACCAGCGCAGTGATGGGCACCGTGGGCAACGGCCTGCTGGGCCAGGTATGCCCAACCGAGAATACCACCGGT TCTGCGGTGGATATTCAACACGTGCTAAATGAACTGGTTGATCAGGGCGCGACCCTTGCCGCGATGGAAGTTTCTTCTCA CGGCCTGGTGCAACACCGTGTGGCGGCGTTGCCGTTTGCCGCCGCGGTGTTTACCAACCTGAGCCGCGACCATCTGGATT ATCACGGCGACATGGCCAATTACGAAGCGGCCAAGTGGTCGCTGTTCGCCGGTCACGAAGTGGGCCAGGCGATTATCAAT GCCGATGATGAAGTCGGTCAGCGCTGGTTGAGCCAATTGCCGGATGCGGTGGCCGTCACCATGCAGGATAACCTGCAGCC AGGCTGCCATGGGCGCTGGCTGAAGACTACCGCGGTCAACTATCACGATAACGGCGCGACTATCCACTTCAGCTCAAGCT GGGGCGACGGCGAGATTGAAAGCCGTCTGATGGGAGCCTTCAACGTCAGCAATCTGCTGCTGGCACTGGCGACGCTGCTG TCGTTGGGTTACCCGCTGGCCAAATTGGTTGCCACCGGCAATCAACTGCAGCCGGTCTGCGGCCGCATGGAAGTGTTCAA CGCGCCGGGTAAACCGACGGTAGTGGTTGATTACGCCCACACCCCGGACGCGCTGGAAAAAGCATTGGAAGCCGCACGTC TGCACTGCCTGGGGCAGTTGTGGTGTGTGTTTGGCTGCGGCGGCGATCGTGACAAAGGCAAACGCCCGCTGATGGGCGGC ATCGCCGAACAGTTCGCCGATCGCGTAGTCGTGACCGATGACAACCCGCGTACCGAAGAGCCGCAGGCGATTATCGCCGA TATCCTTACCGGCCTGCTGGACGCCGGACGCGCTCTGGTGATCCACGGTCGTGCGGAAGCGGTAACCAGCGCCATCATGC AAGCCAAGGAACAAGATGTGGTTCTGGTGGCGGGTAAAGGCCACGAGGACTACCAACTGGTGGGGAATCGCCGTTTGGAT TACTCCGATCGTACCACCGTAGCGCGTCTGCTGGGGGTAGTAGCATGA
Upstream 100 bases:
>100_bases GCCATCATGGGCGGCGTGTTGCGCACCATGAACGTCGAGCCGGACGCGTTGCCTACCGGTGAGAAAAGCGATTTTGTAAT TAACAGAAAAGAGGGTTCAG
Downstream 100 bases:
>100_bases TCCCTGTCTCCCTTCGGACACTGGCCGATGTATTGAGCGCTGAGTTGATCGGCGCCGATTGCCAAATCGTTGAGGTGACG ACAGATACCCGTCAGGTAAC
Product: UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase
Products: NA
Alternate protein names: Meso-A2pm-adding enzyme; Meso-diaminopimelate-adding enzyme; UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; UDP-MurNAc-tripeptide synthetase; UDP-N-acetylmuramyl-tripeptide synthetase [H]
Number of amino acids: Translated: 495; Mature: 494
Protein sequence:
>495_residues MADRNLRDLLAPWVPTAPGRALREMTLDSRIAAAGDLFVAVVGHQADGRRFIPQAIAQGVAAVIAEAEGQAEDGAITEMH GVPVIYLSQLNQRLSALAGRFYHEPAERLRLVGVTGTNGKTTTTQLLAQWGQLLGETSAVMGTVGNGLLGQVCPTENTTG SAVDIQHVLNELVDQGATLAAMEVSSHGLVQHRVAALPFAAAVFTNLSRDHLDYHGDMANYEAAKWSLFAGHEVGQAIIN ADDEVGQRWLSQLPDAVAVTMQDNLQPGCHGRWLKTTAVNYHDNGATIHFSSSWGDGEIESRLMGAFNVSNLLLALATLL SLGYPLAKLVATGNQLQPVCGRMEVFNAPGKPTVVVDYAHTPDALEKALEAARLHCLGQLWCVFGCGGDRDKGKRPLMGG IAEQFADRVVVTDDNPRTEEPQAIIADILTGLLDAGRALVIHGRAEAVTSAIMQAKEQDVVLVAGKGHEDYQLVGNRRLD YSDRTTVARLLGVVA
Sequences:
>Translated_495_residues MADRNLRDLLAPWVPTAPGRALREMTLDSRIAAAGDLFVAVVGHQADGRRFIPQAIAQGVAAVIAEAEGQAEDGAITEMH GVPVIYLSQLNQRLSALAGRFYHEPAERLRLVGVTGTNGKTTTTQLLAQWGQLLGETSAVMGTVGNGLLGQVCPTENTTG SAVDIQHVLNELVDQGATLAAMEVSSHGLVQHRVAALPFAAAVFTNLSRDHLDYHGDMANYEAAKWSLFAGHEVGQAIIN ADDEVGQRWLSQLPDAVAVTMQDNLQPGCHGRWLKTTAVNYHDNGATIHFSSSWGDGEIESRLMGAFNVSNLLLALATLL SLGYPLAKLVATGNQLQPVCGRMEVFNAPGKPTVVVDYAHTPDALEKALEAARLHCLGQLWCVFGCGGDRDKGKRPLMGG IAEQFADRVVVTDDNPRTEEPQAIIADILTGLLDAGRALVIHGRAEAVTSAIMQAKEQDVVLVAGKGHEDYQLVGNRRLD YSDRTTVARLLGVVA >Mature_494_residues ADRNLRDLLAPWVPTAPGRALREMTLDSRIAAAGDLFVAVVGHQADGRRFIPQAIAQGVAAVIAEAEGQAEDGAITEMHG VPVIYLSQLNQRLSALAGRFYHEPAERLRLVGVTGTNGKTTTTQLLAQWGQLLGETSAVMGTVGNGLLGQVCPTENTTGS AVDIQHVLNELVDQGATLAAMEVSSHGLVQHRVAALPFAAAVFTNLSRDHLDYHGDMANYEAAKWSLFAGHEVGQAIINA DDEVGQRWLSQLPDAVAVTMQDNLQPGCHGRWLKTTAVNYHDNGATIHFSSSWGDGEIESRLMGAFNVSNLLLALATLLS LGYPLAKLVATGNQLQPVCGRMEVFNAPGKPTVVVDYAHTPDALEKALEAARLHCLGQLWCVFGCGGDRDKGKRPLMGGI AEQFADRVVVTDDNPRTEEPQAIIADILTGLLDAGRALVIHGRAEAVTSAIMQAKEQDVVLVAGKGHEDYQLVGNRRLDY SDRTTVARLLGVVA
Specific function: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan [H]
COG id: COG0769
COG function: function code M; UDP-N-acetylmuramyl tripeptide synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family. MurE subfamily [H]
Homologues:
Organism=Escherichia coli, GI1786273, Length=495, Percent_Identity=84.040404040404, Blast_Score=816, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR005761 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.13 [H]
Molecular weight: Translated: 52873; Mature: 52741
Theoretical pI: Translated: 5.39; Mature: 5.39
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MADRNLRDLLAPWVPTAPGRALREMTLDSRIAAAGDLFVAVVGHQADGRRFIPQAIAQGV CCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH AAVIAEAEGQAEDGAITEMHGVPVIYLSQLNQRLSALAGRFYHEPAERLRLVGVTGTNGK HHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCC TTTTQLLAQWGQLLGETSAVMGTVGNGLLGQVCPTENTTGSAVDIQHVLNELVDQGATLA HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEE AMEVSSHGLVQHRVAALPFAAAVFTNLSRDHLDYHGDMANYEAAKWSLFAGHEVGQAIIN EEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHEEEECCHHHHHHHHC ADDEVGQRWLSQLPDAVAVTMQDNLQPGCHGRWLKTTAVNYHDNGATIHFSSSWGDGEIE CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCCHHH SRLMGAFNVSNLLLALATLLSLGYPLAKLVATGNQLQPVCGRMEVFNAPGKPTVVVDYAH HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHCCHHEECCCCCCEEEEEECC TPDALEKALEAARLHCLGQLWCVFGCGGDRDKGKRPLMGGIAEQFADRVVVTDDNPRTEE CHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCC PQAIIADILTGLLDAGRALVIHGRAEAVTSAIMQAKEQDVVLVAGKGHEDYQLVGNRRLD HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCC YSDRTTVARLLGVVA CCHHHHHHHHHHHCC >Mature Secondary Structure ADRNLRDLLAPWVPTAPGRALREMTLDSRIAAAGDLFVAVVGHQADGRRFIPQAIAQGV CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHH AAVIAEAEGQAEDGAITEMHGVPVIYLSQLNQRLSALAGRFYHEPAERLRLVGVTGTNGK HHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCC TTTTQLLAQWGQLLGETSAVMGTVGNGLLGQVCPTENTTGSAVDIQHVLNELVDQGATLA HHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCEEE AMEVSSHGLVQHRVAALPFAAAVFTNLSRDHLDYHGDMANYEAAKWSLFAGHEVGQAIIN EEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHEEEECCHHHHHHHHC ADDEVGQRWLSQLPDAVAVTMQDNLQPGCHGRWLKTTAVNYHDNGATIHFSSSWGDGEIE CCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEEEEEECCCCEEEEECCCCCCHHH SRLMGAFNVSNLLLALATLLSLGYPLAKLVATGNQLQPVCGRMEVFNAPGKPTVVVDYAH HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHCCHHEECCCCCCEEEEEECC TPDALEKALEAARLHCLGQLWCVFGCGGDRDKGKRPLMGGIAEQFADRVVVTDDNPRTEE CHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCEEEEECCCCCCCC PQAIIADILTGLLDAGRALVIHGRAEAVTSAIMQAKEQDVVLVAGKGHEDYQLVGNRRLD HHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCC YSDRTTVARLLGVVA CCHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA