Click here to switch to the map view.

The map label for this gene is dipZ [H]

Identifier: 157368650

GI number: 157368650

Start: 452135

End: 453820

Strand: Reverse

Name: dipZ [H]

Synonym: Spro_0403

Alternate gene names: 157368650

Gene position: 453820-452135 (Counterclockwise)

Preceding gene: 157368651

Following gene: 157368649

Centisome position: 8.33

GC content: 58.36

Gene sequence:

>1686_bases
TTGATATTCCTGCTTTGCAGCCTGTTTTTTTTGCCACAGGCGGCTCAGGCATCGCTGTTCGCCCCTAACGGCGGCACCCA
ATTCGTGCCGGTCGATCAGGCGTTTGCCTTCGATTTTAAGCAGCAAGACCACCAGTTGACGCTGAACTGGCAAATTCGCC
CCGGTTATTACCTCTATCGCCAGCAAATCAAGCTGGTGCCACAGCAGGCAAGGTTAGGCTCCTTTGAGCTACCGGCCGGG
CTGAGCCACAAGGATGAGTTCTTCGGCGAAGTCTCTATTTTCAAACAACAGCTGAATCTGCCGATCCCACTGCAGCAGGC
CACCAGCGGCGCCAGCCTGAGCGTGACTTATCAGGGCTGCGCCGAAGCAGGTTTCTGCTATCCGCCGGAAACGCGGGTGA
TCCCGCTGGATGCGGTAAGTGCCACAACCGCACTGCCAGTCAGCGCACCAGAAGAACCGGTGCCGGCCAGTCTGCCGTTC
TCCCCCCTGTGGGCACTGCTGATTGGCATTGGCATTGCTTTCACCCCCTGCGTGTTGCCGATGTATCCACTGATTTCCGG
CATCATTCTTGGGCGTGAAAAACCGCACAGCAGCGGACGTATACTGGCACTGGCGGTGGTTTACGTACAGGGCATGGCGC
TGACCTACACCTTGCTGGGTTTGGTGGTTGCCGCCGCCGGCTTGCAATTCCAGGCAGCGCTGCAACATCCGTATGTGCTC
ATCGGCCTGTCAGTGCTGTTTATCGCGCTGGCACTGTCGATGTTCGGTCTGTATTCGCTGCAGTTACCTTCTTCACTGCA
AACCCGGCTGGCGGGCTGGAGCAATAGCCAACAAGGCGGTTCGCTGCCTGGCGTATTCCTGATGGGCGCGCTGGCCGGGC
TGATTTGCTCCCCTTGCACCACAGCGCCGCTTAGCGCCATCCTGTTGTACATTGCCCAAAGCGGCAATATGTGGGCCGGC
GGTGGCACTTTGTATCTGTATGCGCTGGGGATGGGCATCCCGCTGGTGCTGGTGACCCTGTTCGGTAACCGTCTGTTGCC
ACGCAGTGGCCCATGGATGCAGTATGTCAAAGAGGCGTTCGGCTTTGTGATCCTGGCGCTGCCGGTATTCCTGCTGGAAC
GAGTGATCGGTGATGTGTGGGGACTACGGCTGTGGAGCCTGCTTGGCCTGGCGTTCTTCGGCTGGGCCTTCGCGCTGAGC
CTGAAGACTTCCCGCGGCTGGGTACGGGCATTGCAATTACTGCTGCTGGCTGCGGCCGTCATTGCTGCGCGACCGCTGCA
AGACTGGGCCTTTGGCATCAGCAGCGCACAGCAGGCAGCGGTACAACACCTGAACTTCACGCGTATCAGTAATGTAGATC
AGCTCAATGCTGCACTGCAGCAGGCGCAGGGGAAACCGGTGATGCTGGATCTGTACGCCGACTGGTGCGTCGCTTGCAAG
GAGTTCGAGAAATATACCTTCAGCGATACGCGCGTTCAGGCCGCGCTTGCCAACACCGTGCTGCTGCAGGCGGATGTCAC
GGCCAACAATGCCGAGCAGGTCGCGCTCCTTAAACACCTGAAAGTCCTGGGATTACCAACTATTCTGTTCTTTAACGGCA
CGGGGCAAGAGTCAACCAGCCAACGGGTTACCGGATTTATGGATGCCGCGGCATTCAACGCGCATTTGCAGAAAACGGTG
CAATAA

Upstream 100 bases:

>100_bases
ACCTGAAACAACATCACCCGTATCAAACGCCCGAGCTGTTGGTGCTGCCGGTGATGGCTGGAGATAAAGACTACCTGTTA
TGGATCAACGCCTCATTAAA

Downstream 100 bases:

>100_bases
ATAACACTGAGGATCGGAACCGAATTTGGAGGAAGCACAAGTGCAACGTGAACACGTCCTTGATACGGCACTGGGGCTGT
TGGAACAACAGGGCCTGGCG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MIFLLCSLFFLPQAAQASLFAPNGGTQFVPVDQAFAFDFKQQDHQLTLNWQIRPGYYLYRQQIKLVPQQARLGSFELPAG
LSHKDEFFGEVSIFKQQLNLPIPLQQATSGASLSVTYQGCAEAGFCYPPETRVIPLDAVSATTALPVSAPEEPVPASLPF
SPLWALLIGIGIAFTPCVLPMYPLISGIILGREKPHSSGRILALAVVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVL
IGLSVLFIALALSMFGLYSLQLPSSLQTRLAGWSNSQQGGSLPGVFLMGALAGLICSPCTTAPLSAILLYIAQSGNMWAG
GGTLYLYALGMGIPLVLVTLFGNRLLPRSGPWMQYVKEAFGFVILALPVFLLERVIGDVWGLRLWSLLGLAFFGWAFALS
LKTSRGWVRALQLLLLAAAVIAARPLQDWAFGISSAQQAAVQHLNFTRISNVDQLNAALQQAQGKPVMLDLYADWCVACK
EFEKYTFSDTRVQAALANTVLLQADVTANNAEQVALLKHLKVLGLPTILFFNGTGQESTSQRVTGFMDAAAFNAHLQKTV
Q

Sequences:

>Translated_561_residues
MIFLLCSLFFLPQAAQASLFAPNGGTQFVPVDQAFAFDFKQQDHQLTLNWQIRPGYYLYRQQIKLVPQQARLGSFELPAG
LSHKDEFFGEVSIFKQQLNLPIPLQQATSGASLSVTYQGCAEAGFCYPPETRVIPLDAVSATTALPVSAPEEPVPASLPF
SPLWALLIGIGIAFTPCVLPMYPLISGIILGREKPHSSGRILALAVVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVL
IGLSVLFIALALSMFGLYSLQLPSSLQTRLAGWSNSQQGGSLPGVFLMGALAGLICSPCTTAPLSAILLYIAQSGNMWAG
GGTLYLYALGMGIPLVLVTLFGNRLLPRSGPWMQYVKEAFGFVILALPVFLLERVIGDVWGLRLWSLLGLAFFGWAFALS
LKTSRGWVRALQLLLLAAAVIAARPLQDWAFGISSAQQAAVQHLNFTRISNVDQLNAALQQAQGKPVMLDLYADWCVACK
EFEKYTFSDTRVQAALANTVLLQADVTANNAEQVALLKHLKVLGLPTILFFNGTGQESTSQRVTGFMDAAAFNAHLQKTV
Q
>Mature_561_residues
MIFLLCSLFFLPQAAQASLFAPNGGTQFVPVDQAFAFDFKQQDHQLTLNWQIRPGYYLYRQQIKLVPQQARLGSFELPAG
LSHKDEFFGEVSIFKQQLNLPIPLQQATSGASLSVTYQGCAEAGFCYPPETRVIPLDAVSATTALPVSAPEEPVPASLPF
SPLWALLIGIGIAFTPCVLPMYPLISGIILGREKPHSSGRILALAVVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVL
IGLSVLFIALALSMFGLYSLQLPSSLQTRLAGWSNSQQGGSLPGVFLMGALAGLICSPCTTAPLSAILLYIAQSGNMWAG
GGTLYLYALGMGIPLVLVTLFGNRLLPRSGPWMQYVKEAFGFVILALPVFLLERVIGDVWGLRLWSLLGLAFFGWAFALS
LKTSRGWVRALQLLLLAAAVIAARPLQDWAFGISSAQQAAVQHLNFTRISNVDQLNAALQQAQGKPVMLDLYADWCVACK
EFEKYTFSDTRVQAALANTVLLQADVTANNAEQVALLKHLKVLGLPTILFFNGTGQESTSQRVTGFMDAAAFNAHLQKTV
Q

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=561, Percent_Identity=69.5187165775401, Blast_Score=796, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 60661; Mature: 60661

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFLLCSLFFLPQAAQASLFAPNGGTQFVPVDQAFAFDFKQQDHQLTLNWQIRPGYYLYR
CHHHHHHHHHCCCCCCCEEECCCCCCEEEECCHHHHCCCCCCCCEEEEEEEECCCHHHHH
QQIKLVPQQARLGSFELPAGLSHKDEFFGEVSIFKQQLNLPIPLQQATSGASLSVTYQGC
HHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCC
AEAGFCYPPETRVIPLDAVSATTALPVSAPEEPVPASLPFSPLWALLIGIGIAFTPCVLP
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MYPLISGIILGREKPHSSGRILALAVVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHH
IGLSVLFIALALSMFGLYSLQLPSSLQTRLAGWSNSQQGGSLPGVFLMGALAGLICSPCT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TAPLSAILLYIAQSGNMWAGGGTLYLYALGMGIPLVLVTLFGNRLLPRSGPWMQYVKEAF
CHHHHHHHHHHHCCCCEEECCCEEEEEEHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GFVILALPVFLLERVIGDVWGLRLWSLLGLAFFGWAFALSLKTSRGWVRALQLLLLAAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHH
IAARPLQDWAFGISSAQQAAVQHLNFTRISNVDQLNAALQQAQGKPVMLDLYADWCVACK
HHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHH
EFEKYTFSDTRVQAALANTVLLQADVTANNAEQVALLKHLKVLGLPTILFFNGTGQESTS
HHHHCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
QRVTGFMDAAAFNAHLQKTVQ
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIFLLCSLFFLPQAAQASLFAPNGGTQFVPVDQAFAFDFKQQDHQLTLNWQIRPGYYLYR
CHHHHHHHHHCCCCCCCEEECCCCCCEEEECCHHHHCCCCCCCCEEEEEEEECCCHHHHH
QQIKLVPQQARLGSFELPAGLSHKDEFFGEVSIFKQQLNLPIPLQQATSGASLSVTYQGC
HHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEECCC
AEAGFCYPPETRVIPLDAVSATTALPVSAPEEPVPASLPFSPLWALLIGIGIAFTPCVLP
CCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
MYPLISGIILGREKPHSSGRILALAVVYVQGMALTYTLLGLVVAAAGLQFQAALQHPYVL
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHH
IGLSVLFIALALSMFGLYSLQLPSSLQTRLAGWSNSQQGGSLPGVFLMGALAGLICSPCT
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
TAPLSAILLYIAQSGNMWAGGGTLYLYALGMGIPLVLVTLFGNRLLPRSGPWMQYVKEAF
CHHHHHHHHHHHCCCCEEECCCEEEEEEHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
GFVILALPVFLLERVIGDVWGLRLWSLLGLAFFGWAFALSLKTSRGWVRALQLLLLAAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHH
IAARPLQDWAFGISSAQQAAVQHLNFTRISNVDQLNAALQQAQGKPVMLDLYADWCVACK
HHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHH
EFEKYTFSDTRVQAALANTVLLQADVTANNAEQVALLKHLKVLGLPTILFFNGTGQESTS
HHHHCCCCHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHH
QRVTGFMDAAAFNAHLQKTVQ
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA