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The map label for this gene is cutA [H]

Identifier: 157368651

GI number: 157368651

Start: 453817

End: 454140

Strand: Reverse

Name: cutA [H]

Synonym: Spro_0404

Alternate gene names: 157368651

Gene position: 454140-453817 (Counterclockwise)

Preceding gene: 157368652

Following gene: 157368650

Centisome position: 8.33

GC content: 53.7

Gene sequence:

>324_bases
ATGTCTGATTGCGAAGCTGTCGTCATACTCTGCACCGCACCCGATGAAGCCACGGCTCAAGACCTGGCGGCCCGGGTTTT
GGGGGAAAAGCTGGCGGCCTGTGTCACGCTGCTGCCCGGCGCGTCATCGTTATATTACTGGGAAGGGAAACTGGAACAGG
AGTACGAAGTGCAGATGCTGTTTAAAAGCCAACGCAGCCATCAAGATGCCCTGCTCAACTACCTGAAACAACATCACCCG
TATCAAACGCCCGAGCTGTTGGTGCTGCCGGTGATGGCTGGAGATAAAGACTACCTGTTATGGATCAACGCCTCATTAAA
TTGA

Upstream 100 bases:

>100_bases
CCGGTTTCCCCAACCCGCCCCACTGGCGATAAACTCGCCTTCTAGCCGACCGTCCTTCAAGGTATAGTGCCCACTGATAA
TCTCGATGAGAGGGCTGAAG

Downstream 100 bases:

>100_bases
TATTCCTGCTTTGCAGCCTGTTTTTTTTGCCACAGGCGGCTCAGGCATCGCTGTTCGCCCCTAACGGCGGCACCCAATTC
GTGCCGGTCGATCAGGCGTT

Product: divalent-cation tolerance protein CutA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSDCEAVVILCTAPDEATAQDLAARVLGEKLAACVTLLPGASSLYYWEGKLEQEYEVQMLFKSQRSHQDALLNYLKQHHP
YQTPELLVLPVMAGDKDYLLWINASLN

Sequences:

>Translated_107_residues
MSDCEAVVILCTAPDEATAQDLAARVLGEKLAACVTLLPGASSLYYWEGKLEQEYEVQMLFKSQRSHQDALLNYLKQHHP
YQTPELLVLPVMAGDKDYLLWINASLN
>Mature_106_residues
SDCEAVVILCTAPDEATAQDLAARVLGEKLAACVTLLPGASSLYYWEGKLEQEYEVQMLFKSQRSHQDALLNYLKQHHPY
QTPELLVLPVMAGDKDYLLWINASLN

Specific function: Involved in resistance toward heavy metals [H]

COG id: COG1324

COG function: function code P; Uncharacterized protein involved in tolerance to divalent cations

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutA family [H]

Homologues:

Organism=Homo sapiens, GI62526024, Length=94, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=5e-19,
Organism=Homo sapiens, GI62526022, Length=94, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=5e-19,
Organism=Homo sapiens, GI7706244, Length=94, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=5e-19,
Organism=Homo sapiens, GI62198241, Length=94, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=6e-19,
Organism=Homo sapiens, GI62526026, Length=94, Percent_Identity=40.4255319148936, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1790579, Length=106, Percent_Identity=76.4150943396226, Blast_Score=170, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI32565476, Length=101, Percent_Identity=32.6732673267327, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24641937, Length=95, Percent_Identity=34.7368421052632, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004323
- InterPro:   IPR011322 [H]

Pfam domain/function: PF03091 CutA1 [H]

EC number: NA

Molecular weight: Translated: 11998; Mature: 11867

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDCEAVVILCTAPDEATAQDLAARVLGEKLAACVTLLPGASSLYYWEGKLEQEYEVQML
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
FKSQRSHQDALLNYLKQHHPYQTPELLVLPVMAGDKDYLLWINASLN
HHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCC
>Mature Secondary Structure 
SDCEAVVILCTAPDEATAQDLAARVLGEKLAACVTLLPGASSLYYWEGKLEQEYEVQML
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
FKSQRSHQDALLNYLKQHHPYQTPELLVLPVMAGDKDYLLWINASLN
HHHHCCHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA