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The map label for this gene is murR [H]

Identifier: 156978250

GI number: 156978250

Start: 2132521

End: 2132850

Strand: Direct

Name: murR [H]

Synonym: VIBHAR_07056

Alternate gene names: 156978250

Gene position: 2132521-2132850 (Clockwise)

Preceding gene: 156978249

Following gene: 156978252

Centisome position: 96.76

GC content: 49.09

Gene sequence:

>330_bases
GTGCAGCTCTCTTCGCAAGACGTGCAGATTGCGATTTCTTTTTCAGGAGAACGCAAAGAGATTCTGGTGGCGGCGGAAGC
GGCGAAAGAGCAGGGAGCAAAAGTAATTGCTTTGTCTGCACCGGGGAGAAGCCGATTGAGAGACATTGCCGACATCACGT
TTGATACCATCGCCAATGAAACAGAGCATCGCAGCTCTTCCATTGCTTCGCGTACGGCACAAAACGTGATTACGGATCTG
CTGTTTATTATTTTGGTGCAGCAAAGGGACGAAAGCGCGCGTCAGTTGATCAGTGATATCAGTACCGATATCAAGCAGAT
CCTTACTTGA

Upstream 100 bases:

>100_bases
ACGTGAGCATTTACCAAAGCGAACGCAGGCGTTTATTGAGCATTTCAAACAGCAATCATTTTAAGCTGTAATCATTTTAA
ACTGACAGGTTGTCTTGAGT

Downstream 100 bases:

>100_bases
TCGCTTCGTATAGCTAGAAATTAAAGATCTGGATCGTGCTGCAACAAAGCAATAAACGCATCGAGATGCTTTTCGATCGT
GAGATCCGCCGAGATCGGTG

Product: hypothetical protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MQLSSQDVQIAISFSGERKEILVAAEAAKEQGAKVIALSAPGRSRLRDIADITFDTIANETEHRSSSIASRTAQNVITDL
LFIILVQQRDESARQLISDISTDIKQILT

Sequences:

>Translated_109_residues
MQLSSQDVQIAISFSGERKEILVAAEAAKEQGAKVIALSAPGRSRLRDIADITFDTIANETEHRSSSIASRTAQNVITDL
LFIILVQQRDESARQLISDISTDIKQILT
>Mature_109_residues
MQLSSQDVQIAISFSGERKEILVAAEAAKEQGAKVIALSAPGRSRLRDIADITFDTIANETEHRSSSIASRTAQNVITDL
LFIILVQQRDESARQLISDISTDIKQILT

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=95, Percent_Identity=54.7368421052632, Blast_Score=103, Evalue=4e-24,
Organism=Escherichia coli, GI87082130, Length=105, Percent_Identity=36.1904761904762, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 11940; Mature: 11940

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSSQDVQIAISFSGERKEILVAAEAAKEQGAKVIALSAPGRSRLRDIADITFDTIANE
CCCCCCCEEEEEEECCCCCEEEEEHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCH
TEHRSSSIASRTAQNVITDLLFIILVQQRDESARQLISDISTDIKQILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLSSQDVQIAISFSGERKEILVAAEAAKEQGAKVIALSAPGRSRLRDIADITFDTIANE
CCCCCCCEEEEEEECCCCCEEEEEHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCH
TEHRSSSIASRTAQNVITDLLFIILVQQRDESARQLISDISTDIKQILT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA