Click here to switch to the map view.

The map label for this gene is yegE [H]

Identifier: 156977009

GI number: 156977009

Start: 980404

End: 982362

Strand: Reverse

Name: yegE [H]

Synonym: VIBHAR_05794

Alternate gene names: 156977009

Gene position: 982362-980404 (Counterclockwise)

Preceding gene: 156977013

Following gene: 156977008

Centisome position: 44.57

GC content: 44.41

Gene sequence:

>1959_bases
ATGTCATTACGAGCAAAGCTAATATGGCCGATTCTCGCTTTCATCACGGTCATCTTTGTTACATCTCAAAGTTACACGTC
ATACATTACTTATCAATCCGCGAAACATGAACTGGTTGATCAAACCAAGGTTCTCATCAACGATGTCTCTCATTCAATTA
AAGATGCGCTCGCAACAAAGAACAAGCAACAAGCACAATTGATTTTGGCTGATTTCCTGAAGGAGCCAAACGTATCACGC
GTCAAGCTTTACGACAAAGAGAATCAGTTATTTGCGATCTTTACTTTGGATGGTGCGACGCTCCCTTCGCCGACAGTGAC
AGAGCGTAGTCGTCTGCATGAGGTGGGTTACGCTCTTTCGGCGCACTTTCTGTATGTATTAGAACCTATCATTCATGAAG
GCAAGGTTGTCGGTACAATACGGGTCACTATTTCCCAGTTGCCTCTGATGGAAGTGAGAGATGCGCTTCTCCAAGATGGG
CTGCTTTTCTTGGCTATTCTTTTGCTCAGTAGTATTGTGTTTTACATTGGTGTAGAGCGCCGTGTACTGCGACCAATCAT
TGAAGTGAATCGTGCGCTTCAGGACGTAGCAAATGGTCATCATCTTACTGGCCGTATTGAGCATCGCGCAAAAGATGAAG
TCGGTGAGTTGGTGTCTTCTTTTAACTTCATGCTCGATCGCCAACAAAGATTGGAGAAACAACGTAAGCACAGCTTGGAA
GTATTAAAGCGCCGTAAAGCCTTCGCTGAAGAAGTCGTGGACTCTATTCAAGATGCACTGATCGTGACTGACAATTTAGG
GCGTGTAATACATTGCAATAGGGCGACACATCGAATTTTTGAAAAGACCTACCATGGTATAGAAACCGCTAACATTTGTG
ATTTGATTCAGACTAAAACACCAAATGAGCTCAGACAAATTTTGAGTCGTGGCTTAGAGTGCGATGACATCCACCTTGAA
AATAGGGAAGGCGAACAGCAACTGAGCCTAACGAGCCGACTTCTTAGCAAGCACGGCTACCTTTTATTCGTGATTCAAGA
TATTACTGAAATTGAAGAAGCAATGAATCGTCAGCGTGTCGCGGGGCGTGTGTTTGAGAGCAGTCAAGATGGACTTGTTG
TACTGAATCATCAAGGCATCATTACCATGGTGAACCCCGCAGTGACCAAACTTGTTGGCTTAGATTCGGACCAATTAGTT
GGTAAGCCATTCATAAAATCTATTCGCTGGCGCAAACTGCAAGCCATGATGCCAAGCATCCTCGAGTCGATCGATAACTA
TGGCATGTGGCAAGGGGAAGTCATTGAAAAGAATCATCTAGGTCAGCTCATACCCATGTTCGCAAGAGTAAATCTTATCA
TTAAGAGCGAAGATCAAAATGCGTATGACATGGTGATTATTTTAACCGACCTCTCAAGTGCAAAAGAGATGGAGCGTCTA
GAATACTTAGCTCATCACGATGCGTTGACAGGGCTGGCGAATCGTTCCAAGTTCCACCTAGAGCTTGAAGAATTAGTACA
AAGATCAGGCTATTTACGTGACGAGTTTGCGGTACTTTATCTCGACTTGGACGGCTTTAAAGGTATCAACGATACTTATG
GTCATGATGCGGGCGATGAAGTGCTCAAGATCGTTGCTAAACGTATGACTGGTGCAACGCGGCACAGCGATTTGATCGCA
CGCTTGTCCGGTGATGAGTTCGTAATGTTGGTTAATCCTGCCAATCAAAAAGTCGTAACACGAATCGCAGAACAGCTGCT
TGAGACGATTTGTTCACCAATTGAATACCGAGGCACACTCCTTAAAGTTGGCGTTAGTATTGGTGTGAAACTGGTTGGCG
TAAATGAACGAGATGCGACCAGAATTCTTAAGAGCGCGGATACTGCCATGTATCAAGCGAAGAAAGCAGGTAAAGGCCAA
GCATTTTTAATGGGTTGCGAATCCCCAGATACAGTTTAA

Upstream 100 bases:

>100_bases
TTTCATTGCACGTCGTGTTAATCTTATTTCTTCTTTTTGTGTGATAGTTTGCATAGCAATCCTTTTGGTCTTTTGATTGC
TTTCTGCGACAGGAATATAT

Downstream 100 bases:

>100_bases
AAACGGGTTAGAAACCTTTAGACTATCCCGATTCGCGTCAGAAGGAATGATAAAATGAAAGTACTTGTTACGGGGGGTAT
GGGCTACATTGGCAGCCACA

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 652; Mature: 651

Protein sequence:

>652_residues
MSLRAKLIWPILAFITVIFVTSQSYTSYITYQSAKHELVDQTKVLINDVSHSIKDALATKNKQQAQLILADFLKEPNVSR
VKLYDKENQLFAIFTLDGATLPSPTVTERSRLHEVGYALSAHFLYVLEPIIHEGKVVGTIRVTISQLPLMEVRDALLQDG
LLFLAILLLSSIVFYIGVERRVLRPIIEVNRALQDVANGHHLTGRIEHRAKDEVGELVSSFNFMLDRQQRLEKQRKHSLE
VLKRRKAFAEEVVDSIQDALIVTDNLGRVIHCNRATHRIFEKTYHGIETANICDLIQTKTPNELRQILSRGLECDDIHLE
NREGEQQLSLTSRLLSKHGYLLFVIQDITEIEEAMNRQRVAGRVFESSQDGLVVLNHQGIITMVNPAVTKLVGLDSDQLV
GKPFIKSIRWRKLQAMMPSILESIDNYGMWQGEVIEKNHLGQLIPMFARVNLIIKSEDQNAYDMVIILTDLSSAKEMERL
EYLAHHDALTGLANRSKFHLELEELVQRSGYLRDEFAVLYLDLDGFKGINDTYGHDAGDEVLKIVAKRMTGATRHSDLIA
RLSGDEFVMLVNPANQKVVTRIAEQLLETICSPIEYRGTLLKVGVSIGVKLVGVNERDATRILKSADTAMYQAKKAGKGQ
AFLMGCESPDTV

Sequences:

>Translated_652_residues
MSLRAKLIWPILAFITVIFVTSQSYTSYITYQSAKHELVDQTKVLINDVSHSIKDALATKNKQQAQLILADFLKEPNVSR
VKLYDKENQLFAIFTLDGATLPSPTVTERSRLHEVGYALSAHFLYVLEPIIHEGKVVGTIRVTISQLPLMEVRDALLQDG
LLFLAILLLSSIVFYIGVERRVLRPIIEVNRALQDVANGHHLTGRIEHRAKDEVGELVSSFNFMLDRQQRLEKQRKHSLE
VLKRRKAFAEEVVDSIQDALIVTDNLGRVIHCNRATHRIFEKTYHGIETANICDLIQTKTPNELRQILSRGLECDDIHLE
NREGEQQLSLTSRLLSKHGYLLFVIQDITEIEEAMNRQRVAGRVFESSQDGLVVLNHQGIITMVNPAVTKLVGLDSDQLV
GKPFIKSIRWRKLQAMMPSILESIDNYGMWQGEVIEKNHLGQLIPMFARVNLIIKSEDQNAYDMVIILTDLSSAKEMERL
EYLAHHDALTGLANRSKFHLELEELVQRSGYLRDEFAVLYLDLDGFKGINDTYGHDAGDEVLKIVAKRMTGATRHSDLIA
RLSGDEFVMLVNPANQKVVTRIAEQLLETICSPIEYRGTLLKVGVSIGVKLVGVNERDATRILKSADTAMYQAKKAGKGQ
AFLMGCESPDTV
>Mature_651_residues
SLRAKLIWPILAFITVIFVTSQSYTSYITYQSAKHELVDQTKVLINDVSHSIKDALATKNKQQAQLILADFLKEPNVSRV
KLYDKENQLFAIFTLDGATLPSPTVTERSRLHEVGYALSAHFLYVLEPIIHEGKVVGTIRVTISQLPLMEVRDALLQDGL
LFLAILLLSSIVFYIGVERRVLRPIIEVNRALQDVANGHHLTGRIEHRAKDEVGELVSSFNFMLDRQQRLEKQRKHSLEV
LKRRKAFAEEVVDSIQDALIVTDNLGRVIHCNRATHRIFEKTYHGIETANICDLIQTKTPNELRQILSRGLECDDIHLEN
REGEQQLSLTSRLLSKHGYLLFVIQDITEIEEAMNRQRVAGRVFESSQDGLVVLNHQGIITMVNPAVTKLVGLDSDQLVG
KPFIKSIRWRKLQAMMPSILESIDNYGMWQGEVIEKNHLGQLIPMFARVNLIIKSEDQNAYDMVIILTDLSSAKEMERLE
YLAHHDALTGLANRSKFHLELEELVQRSGYLRDEFAVLYLDLDGFKGINDTYGHDAGDEVLKIVAKRMTGATRHSDLIAR
LSGDEFVMLVNPANQKVVTRIAEQLLETICSPIEYRGTLLKVGVSIGVKLVGVNERDATRILKSADTAMYQAKKAGKGQA
FLMGCESPDTV

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=323, Percent_Identity=28.7925696594427, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787541, Length=284, Percent_Identity=28.8732394366197, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1787262, Length=195, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081881, Length=178, Percent_Identity=35.3932584269663, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786584, Length=170, Percent_Identity=32.3529411764706, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788956, Length=155, Percent_Identity=39.3548387096774, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081977, Length=163, Percent_Identity=32.5153374233129, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=30.2469135802469, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082007, Length=166, Percent_Identity=30.1204819277108, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=30.635838150289, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1788085, Length=170, Percent_Identity=28.8235294117647, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=28.3018867924528, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081974, Length=152, Percent_Identity=33.5526315789474, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081921, Length=175, Percent_Identity=27.4285714285714, Blast_Score=63, Evalue=7e-11,
Organism=Escherichia coli, GI1787056, Length=173, Percent_Identity=31.2138728323699, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 73594; Mature: 73463

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRAKLIWPILAFITVIFVTSQSYTSYITYQSAKHELVDQTKVLINDVSHSIKDALATK
CCCCHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NKQQAQLILADFLKEPNVSRVKLYDKENQLFAIFTLDGATLPSPTVTERSRLHEVGYALS
CHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AHFLYVLEPIIHEGKVVGTIRVTISQLPLMEVRDALLQDGLLFLAILLLSSIVFYIGVER
HHHHHHHHHHHHCCEEEEEEEEEHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
RVLRPIIEVNRALQDVANGHHLTGRIEHRAKDEVGELVSSFNFMLDRQQRLEKQRKHSLE
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRRKAFAEEVVDSIQDALIVTDNLGRVIHCNRATHRIFEKTYHGIETANICDLIQTKT
HHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCC
PNELRQILSRGLECDDIHLENREGEQQLSLTSRLLSKHGYLLFVIQDITEIEEAMNRQRV
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHH
AGRVFESSQDGLVVLNHQGIITMVNPAVTKLVGLDSDQLVGKPFIKSIRWRKLQAMMPSI
HHHHHCCCCCCEEEEECCCEEEEECHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHH
LESIDNYGMWQGEVIEKNHLGQLIPMFARVNLIIKSEDQNAYDMVIILTDLSSAKEMERL
HHHHHHCCCCCCCEECHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEECCCCHHHHHHH
EYLAHHDALTGLANRSKFHLELEELVQRSGYLRDEFAVLYLDLDGFKGINDTYGHDAGDE
HHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
VLKIVAKRMTGATRHSDLIARLSGDEFVMLVNPANQKVVTRIAEQLLETICSPIEYRGTL
HHHHHHHHHCCCCHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHCCHH
LKVGVSIGVKLVGVNERDATRILKSADTAMYQAKKAGKGQAFLMGCESPDTV
EEEEHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SLRAKLIWPILAFITVIFVTSQSYTSYITYQSAKHELVDQTKVLINDVSHSIKDALATK
CCCHHHHHHHHHHHHHHHHCCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NKQQAQLILADFLKEPNVSRVKLYDKENQLFAIFTLDGATLPSPTVTERSRLHEVGYALS
CHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
AHFLYVLEPIIHEGKVVGTIRVTISQLPLMEVRDALLQDGLLFLAILLLSSIVFYIGVER
HHHHHHHHHHHHCCEEEEEEEEEHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
RVLRPIIEVNRALQDVANGHHLTGRIEHRAKDEVGELVSSFNFMLDRQQRLEKQRKHSLE
HHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLKRRKAFAEEVVDSIQDALIVTDNLGRVIHCNRATHRIFEKTYHGIETANICDLIQTKT
HHHHHHHHHHHHHHHHHHHEEEECCCCCEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCC
PNELRQILSRGLECDDIHLENREGEQQLSLTSRLLSKHGYLLFVIQDITEIEEAMNRQRV
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHH
AGRVFESSQDGLVVLNHQGIITMVNPAVTKLVGLDSDQLVGKPFIKSIRWRKLQAMMPSI
HHHHHCCCCCCEEEEECCCEEEEECHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHH
LESIDNYGMWQGEVIEKNHLGQLIPMFARVNLIIKSEDQNAYDMVIILTDLSSAKEMERL
HHHHHHCCCCCCCEECHHHHHHHHHHHHHEEEEEEECCCCCEEEEEEEECCCCHHHHHHH
EYLAHHDALTGLANRSKFHLELEELVQRSGYLRDEFAVLYLDLDGFKGINDTYGHDAGDE
HHHHHHHHHHHHCCCCEEEEEHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
VLKIVAKRMTGATRHSDLIARLSGDEFVMLVNPANQKVVTRIAEQLLETICSPIEYRGTL
HHHHHHHHHCCCCHHHHHHHEECCCCEEEEECCCCHHHHHHHHHHHHHHHCCCHHHCCHH
LKVGVSIGVKLVGVNERDATRILKSADTAMYQAKKAGKGQAFLMGCESPDTV
EEEEHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]