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The map label for this gene is galE [H]

Identifier: 156977008

GI number: 156977008

Start: 979333

End: 980349

Strand: Reverse

Name: galE [H]

Synonym: VIBHAR_05793

Alternate gene names: 156977008

Gene position: 980349-979333 (Counterclockwise)

Preceding gene: 156977009

Following gene: 156977005

Centisome position: 44.48

GC content: 46.12

Gene sequence:

>1017_bases
ATGAAAGTACTTGTTACGGGGGGTATGGGCTACATTGGCAGCCACACTTGTATTCAAATGATCGAAGCTGGTATGACACC
AGTGATTCTCGATAACCTTTACAACAGCAAACCAACCGTGCTTGAGCGCATTGAAAAAGTTTGCGGCGTAAAACCAGTAT
TCATTGAAGCTGACATTCGTGATAAAGCCGCGCTTGTCGATGCAATGAAAGCGCACAACATTGAAGCAGTTATCCACTTT
GCTGGCCTTAAAGCGGTGGGTGAGTCTGTAGAAAAGCCACTGGAATACTACGACAACAACGTTAATGGTACGCTTGTTCT
GGTTGATGCAATGCGCGAAGCGGGCGTTAAATCTATCGTATTTAGCTCTTCTGCAACGGTTTATGGTGATCCAGCTTCCG
TGCCAATTATGGAAGATTTCCCAACAAGCGCGACAAACCCATACGGCCGCAGCAAGCTGATGGTAGAAGAATGTTTAACT
GACTTCCAAAAAGCAAACCCTGATTGGAGTATCACGCTGCTTCGCTACTTCAACCCAGTTGGCTCTCATCCAACGGGTGA
GCTTGGTGAAGATCCACAAGGCATTCCAAATAACTTGATGCCATTTGTTTCTCAAGTTGCAGTGGGCCGTCGTGAATTCC
TATCAGTATTTGGTAGTGATTACCCAACAAAAGACGGTACAGGCGTTCGTGACTACATCCATGTAATGGATCTTTCTGAT
GGTCACGTAGCGGCACTAGACAAAGTAGGTAACAAAGCAGGCCTTCATATTTACAACCTTGGTACAGGCAACGGTTACAG
CGTACTAGAAATGGTAAAAGCGTTCGAAGCTGCATCTGGTAAAGAAGTTCCGTTTAAGCTGGTGGATCGTCGCCCTGGTG
ACATTGCTGAATGTTGGGCTGACCCTTCAAAAGCAGCTAACGAACTTGGTTGGAAATCGGTTCGTACGCTTGAAGAGATG
ACAAGTGATACTTGGCGTTGGCAGTCAAATAACCCTCAAGGTTACCCAGACGCTTAA

Upstream 100 bases:

>100_bases
AGGCCAAGCATTTTTAATGGGTTGCGAATCCCCAGATACAGTTTAAAAACGGGTTAGAAACCTTTAGACTATCCCGATTC
GCGTCAGAAGGAATGATAAA

Downstream 100 bases:

>100_bases
AATCTTAAGCTTTACACTTTATTAACAAAAAGGCGCAGTTCTGCGCCTTTTTTGATCTAAATCGGAAAAATTCGTAAATT
ACTGGTTAAAAGGTAGCTTC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKVLVTGGMGYIGSHTCIQMIEAGMTPVILDNLYNSKPTVLERIEKVCGVKPVFIEADIRDKAALVDAMKAHNIEAVIHF
AGLKAVGESVEKPLEYYDNNVNGTLVLVDAMREAGVKSIVFSSSATVYGDPASVPIMEDFPTSATNPYGRSKLMVEECLT
DFQKANPDWSITLLRYFNPVGSHPTGELGEDPQGIPNNLMPFVSQVAVGRREFLSVFGSDYPTKDGTGVRDYIHVMDLSD
GHVAALDKVGNKAGLHIYNLGTGNGYSVLEMVKAFEAASGKEVPFKLVDRRPGDIAECWADPSKAANELGWKSVRTLEEM
TSDTWRWQSNNPQGYPDA

Sequences:

>Translated_338_residues
MKVLVTGGMGYIGSHTCIQMIEAGMTPVILDNLYNSKPTVLERIEKVCGVKPVFIEADIRDKAALVDAMKAHNIEAVIHF
AGLKAVGESVEKPLEYYDNNVNGTLVLVDAMREAGVKSIVFSSSATVYGDPASVPIMEDFPTSATNPYGRSKLMVEECLT
DFQKANPDWSITLLRYFNPVGSHPTGELGEDPQGIPNNLMPFVSQVAVGRREFLSVFGSDYPTKDGTGVRDYIHVMDLSD
GHVAALDKVGNKAGLHIYNLGTGNGYSVLEMVKAFEAASGKEVPFKLVDRRPGDIAECWADPSKAANELGWKSVRTLEEM
TSDTWRWQSNNPQGYPDA
>Mature_338_residues
MKVLVTGGMGYIGSHTCIQMIEAGMTPVILDNLYNSKPTVLERIEKVCGVKPVFIEADIRDKAALVDAMKAHNIEAVIHF
AGLKAVGESVEKPLEYYDNNVNGTLVLVDAMREAGVKSIVFSSSATVYGDPASVPIMEDFPTSATNPYGRSKLMVEECLT
DFQKANPDWSITLLRYFNPVGSHPTGELGEDPQGIPNNLMPFVSQVAVGRREFLSVFGSDYPTKDGTGVRDYIHVMDLSD
GHVAALDKVGNKAGLHIYNLGTGNGYSVLEMVKAFEAASGKEVPFKLVDRRPGDIAECWADPSKAANELGWKSVRTLEEM
TSDTWRWQSNNPQGYPDA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=57.4780058651026, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=57.4780058651026, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=57.4780058651026, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=27.9538904899135, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI42516563, Length=331, Percent_Identity=24.1691842900302, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786974, Length=338, Percent_Identity=64.792899408284, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1788353, Length=365, Percent_Identity=27.9452054794521, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI48994969, Length=356, Percent_Identity=25.561797752809, Blast_Score=78, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=346, Percent_Identity=49.7109826589595, Blast_Score=353, Evalue=6e-98,
Organism=Caenorhabditis elegans, GI71982038, Length=348, Percent_Identity=49.4252873563218, Blast_Score=353, Evalue=7e-98,
Organism=Caenorhabditis elegans, GI17568069, Length=342, Percent_Identity=26.0233918128655, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319493, Length=342, Percent_Identity=48.2456140350877, Blast_Score=335, Evalue=4e-93,
Organism=Drosophila melanogaster, GI19923002, Length=344, Percent_Identity=54.9418604651163, Blast_Score=393, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36869; Mature: 36869

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGMGYIGSHTCIQMIEAGMTPVILDNLYNSKPTVLERIEKVCGVKPVFIEADIR
CEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCC
DKAALVDAMKAHNIEAVIHFAGLKAVGESVEKPLEYYDNNVNGTLVLVDAMREAGVKSIV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCEEE
FSSSATVYGDPASVPIMEDFPTSATNPYGRSKLMVEECLTDFQKANPDWSITLLRYFNPV
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCCC
GSHPTGELGEDPQGIPNNLMPFVSQVAVGRREFLSVFGSDYPTKDGTGVRDYIHVMDLSD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCC
GHVAALDKVGNKAGLHIYNLGTGNGYSVLEMVKAFEAASGKEVPFKLVDRRPGDIAECWA
CCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHHC
DPSKAANELGWKSVRTLEEMTSDTWRWQSNNPQGYPDA
CHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MKVLVTGGMGYIGSHTCIQMIEAGMTPVILDNLYNSKPTVLERIEKVCGVKPVFIEADIR
CEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCCCEEEECCCC
DKAALVDAMKAHNIEAVIHFAGLKAVGESVEKPLEYYDNNVNGTLVLVDAMREAGVKSIV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCEEE
FSSSATVYGDPASVPIMEDFPTSATNPYGRSKLMVEECLTDFQKANPDWSITLLRYFNPV
ECCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHCCC
GSHPTGELGEDPQGIPNNLMPFVSQVAVGRREFLSVFGSDYPTKDGTGVRDYIHVMDLSD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEEEEEECCC
GHVAALDKVGNKAGLHIYNLGTGNGYSVLEMVKAFEAASGKEVPFKLVDRRPGDIAECWA
CCCHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCHHEECCCCCCHHHHHC
DPSKAANELGWKSVRTLEEMTSDTWRWQSNNPQGYPDA
CHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3022232; 8905232; 9278503; 2134186; 8564363; 6301942; 1579570; 8611559; 8931134; 9174344; 9271499; 9708982 [H]