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The map label for this gene is nahR [H]

Identifier: 156976564

GI number: 156976564

Start: 570193

End: 571107

Strand: Direct

Name: nahR [H]

Synonym: VIBHAR_05338

Alternate gene names: 156976564

Gene position: 570193-571107 (Clockwise)

Preceding gene: 156976563

Following gene: 156976565

Centisome position: 25.87

GC content: 46.67

Gene sequence:

>915_bases
GTGCTGAATAACATCAACTTGAATCTGCTGCGCTCTTTGCATGTATTGCTTGAAGAGTGCCATGTGAGCAGAACCGCGGA
GCGTTTGCACATCACTCAATCCGCGGTCAGTCGTCAACTAGCGCAGTTACGCGAATTATGCGGCGACCCTTTATTGGTTC
GGCAGGGTAACCAATTGATTCCCACGCCAAGAGCGCTACTTCTAAAAGAGAAGTTGGACGACTTATTGGCGGAATTCGAT
CACCTTCTCGATGACAAGCCTTTTGAACCCGGGGATTGGAAAGGAGAGTTAGTATTAGCATCGAGTGACTATGTCGCGCA
ATATGTACTCCCTGACATTGCTTCGCACTTTAGTAGTTTTGCTCCTCAGTTGGATATGGCGTATCGACTTTGGCAACCGG
ACTTTCTTGATAAACTTCATGAGACAGGTATTCATATTGCGTCTTCAATTTATCCAGAACAGCCTAAAGGTGTATCCAGT
GTGAAGATTGGTGAGGACTCGTCCGTGTGTTTGATGAAGGCCTCCCACCCGTTAGCAAAGCAAGACCATATTAGTGTCGA
AGATCTAATTTCGTATTCTCACATCAAAGTGAACGGTGGAGGGGATAAAGATTCCTATACTGACTTGGCATTGAGAGAGC
TGGGTTATACACGCCACGTTACCTTCAAGGTGCCTTTCTTTTCTGCTGCTATCAATCGCTTAGTCTCAAGTGAGCATCTG
ATGGTGGTACCCGAGCATATTGCCGTGAATCTCGCGAAGCATTGGGATTTAGCCCACAAAGCGTTGCCACTCGAAACCCC
TACTCATAAGTATTGGTTAATGTGGCATCCAAAGTACGATACGGATCCGGCGCATAAATGGGCGCGAGAGGAGATTCTCT
CGGTTATGCAAACCTCAGAGTATTCCATTCGTTAA

Upstream 100 bases:

>100_bases
ATTACTTTTCACAGCATCCGTGATGGGCTAATTTGCAAACAAGTGGAATATTGGCCGGAAGATTACGCCGCCGCAGATTG
GCGCACACAATGGGTTGAAT

Downstream 100 bases:

>100_bases
TGTGCGTATCTACTGCTTATGATCTGAAATCATAGCTAATATGAAAAACTTTGATTTCTAATTATACCTGCTCCGTTGAT
AGATTAGCGTCAAAGATGGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLNNINLNLLRSLHVLLEECHVSRTAERLHITQSAVSRQLAQLRELCGDPLLVRQGNQLIPTPRALLLKEKLDDLLAEFD
HLLDDKPFEPGDWKGELVLASSDYVAQYVLPDIASHFSSFAPQLDMAYRLWQPDFLDKLHETGIHIASSIYPEQPKGVSS
VKIGEDSSVCLMKASHPLAKQDHISVEDLISYSHIKVNGGGDKDSYTDLALRELGYTRHVTFKVPFFSAAINRLVSSEHL
MVVPEHIAVNLAKHWDLAHKALPLETPTHKYWLMWHPKYDTDPAHKWAREEILSVMQTSEYSIR

Sequences:

>Translated_304_residues
MLNNINLNLLRSLHVLLEECHVSRTAERLHITQSAVSRQLAQLRELCGDPLLVRQGNQLIPTPRALLLKEKLDDLLAEFD
HLLDDKPFEPGDWKGELVLASSDYVAQYVLPDIASHFSSFAPQLDMAYRLWQPDFLDKLHETGIHIASSIYPEQPKGVSS
VKIGEDSSVCLMKASHPLAKQDHISVEDLISYSHIKVNGGGDKDSYTDLALRELGYTRHVTFKVPFFSAAINRLVSSEHL
MVVPEHIAVNLAKHWDLAHKALPLETPTHKYWLMWHPKYDTDPAHKWAREEILSVMQTSEYSIR
>Mature_304_residues
MLNNINLNLLRSLHVLLEECHVSRTAERLHITQSAVSRQLAQLRELCGDPLLVRQGNQLIPTPRALLLKEKLDDLLAEFD
HLLDDKPFEPGDWKGELVLASSDYVAQYVLPDIASHFSSFAPQLDMAYRLWQPDFLDKLHETGIHIASSIYPEQPKGVSS
VKIGEDSSVCLMKASHPLAKQDHISVEDLISYSHIKVNGGGDKDSYTDLALRELGYTRHVTFKVPFFSAAINRLVSSEHL
MVVPEHIAVNLAKHWDLAHKALPLETPTHKYWLMWHPKYDTDPAHKWAREEILSVMQTSEYSIR

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790147, Length=296, Percent_Identity=25, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87081684, Length=315, Percent_Identity=22.8571428571429, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34577; Mature: 34577

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNNINLNLLRSLHVLLEECHVSRTAERLHITQSAVSRQLAQLRELCGDPLLVRQGNQLI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PTPRALLLKEKLDDLLAEFDHLLDDKPFEPGDWKGELVLASSDYVAQYVLPDIASHFSSF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
APQLDMAYRLWQPDFLDKLHETGIHIASSIYPEQPKGVSSVKIGEDSSVCLMKASHPLAK
CCHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCC
QDHISVEDLISYSHIKVNGGGDKDSYTDLALRELGYTRHVTFKVPFFSAAINRLVSSEHL
CCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCE
MVVPEHIAVNLAKHWDLAHKALPLETPTHKYWLMWHPKYDTDPAHKWAREEILSVMQTSE
EEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
YSIR
CCCC
>Mature Secondary Structure
MLNNINLNLLRSLHVLLEECHVSRTAERLHITQSAVSRQLAQLRELCGDPLLVRQGNQLI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
PTPRALLLKEKLDDLLAEFDHLLDDKPFEPGDWKGELVLASSDYVAQYVLPDIASHFSSF
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
APQLDMAYRLWQPDFLDKLHETGIHIASSIYPEQPKGVSSVKIGEDSSVCLMKASHPLAK
CCHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCCCCCCCCEEEECCCCCEEEEECCCCCCC
QDHISVEDLISYSHIKVNGGGDKDSYTDLALRELGYTRHVTFKVPFFSAAINRLVSSEHL
CCCCCHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHCCCCE
MVVPEHIAVNLAKHWDLAHKALPLETPTHKYWLMWHPKYDTDPAHKWAREEILSVMQTSE
EEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCC
YSIR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]