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The map label for this gene is rpl3p [H]

Identifier: 156937755

GI number: 156937755

Start: 857777

End: 858853

Strand: Direct

Name: rpl3p [H]

Synonym: Igni_0964

Alternate gene names: 156937755

Gene position: 857777-858853 (Clockwise)

Preceding gene: 156937754

Following gene: 156937756

Centisome position: 66.11

GC content: 58.31

Gene sequence:

>1077_bases
ATGGGAGCACGAAAGAAGGAAGCGCCGCGTAGAGGCTCTGCGGGGCTACGGCCTAGGAAGAGGGCAGCGAGCATAGTCCC
AAGGGTGAGGAGCTGGCCCTCCATAGACGAGGTCAAGCCCCTAGCGTTCCTAGGTTACAAGGTCGGCATGACCCACGTCA
TCATGATAGACGACAGGGAGCACGTGGACACCGCGGGTCAAGAGATCTTCGTACCCGTGACCGTAATAGAAACCCCGCCC
ATGGTGGTTCTGGGCGCGAGGGTTTACGGTTACGACCCTAACAGAGGTAGGTACGCGCTCACGGAAGTTTGGAGGAACCC
CAGCGACACCATAAAGGAGAAGCTGGGCGAGGAGGTCTTGAGGAAATACTTGTTGGGCATGAGCAAGCGCTTGCCGCACA
TGGTAGAAGAGCTGGGCCCGGGCAAGGGCTTCGAGTTCAAGGTTCCCGAAAAGGAACTCGACGTGGACCCCGAGAAGGTG
GTAGGAGTAGGGCTTATCATGAGCAGCATACCCTTCCTCGCCGGAGGGGTGAGCAAGAAGGCTCCAGACATACTCGAGGT
GAAGGTAGGGGGCTCGCCCGTTGAAGCCTTGGAGTACGCCAAGGGCAAGTTGGGCCAGCTAGTGGACGTGGAGGAAGTCA
TAGAAGCTGGAAAGTTCGTAGACGTGATAGGAGTCACCAAGGGTAAGGGCTTCCAAGGCGTCATAAAGAGGTTCGGCGTC
AAGGAGCTCCCCAAGTGGCACAAGCACCGCAAGGGCTCTAGGAGGGTTGGCGCGAGGAGCTGGGGCAAGGGCACGTCCAG
CTACGTGCCCCAGCCCGGCCAGATGGGCTACCACAGGAGGACCGACTACAACAAGAGGGTTCTGATGATAAGTGACGACC
CCAGCAAGATAAACGTGGAAGGCGGTTGGCTCCACTACGGCTTGGTTAAGAGCAAGTACGTGGTGCTGAAGGGAAGCGTC
TTCGGCCCTCCCAAGAGGCCTATAATAATGCGCCTCCCGGTCAGGCCCCCGGCTTGGGTACCTCCCGGACCCCCCAAGAT
CACTTACATCAGCTTAAGCTCCAAGCAAGGTAACTAA

Upstream 100 bases:

>100_bases
CGTTAAGTACGTGGAGCAGTTCAAGGATAAGTTCCTCTAGCACGGTTTTACCCTCCAAACCCTTCAAATATCCCCTCTCC
TACGCGCCCCGGGGGCGCTC

Downstream 100 bases:

>100_bases
AGGGGTGGTTGGTGATGTACTCCAGCTTGTGGCTCCACGCCAGGGTGTTCGGGTATAACGACTTGAAGAGGCACGTGTGG
GACTTGAACGGCAACCCGGT

Product: 50S ribosomal protein L3P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MGARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSIDEVKPLAFLGYKVGMTHVIMIDDREHVDTAGQEIFVPVTVIETPP
MVVLGARVYGYDPNRGRYALTEVWRNPSDTIKEKLGEEVLRKYLLGMSKRLPHMVEELGPGKGFEFKVPEKELDVDPEKV
VGVGLIMSSIPFLAGGVSKKAPDILEVKVGGSPVEALEYAKGKLGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGV
KELPKWHKHRKGSRRVGARSWGKGTSSYVPQPGQMGYHRRTDYNKRVLMISDDPSKINVEGGWLHYGLVKSKYVVLKGSV
FGPPKRPIIMRLPVRPPAWVPPGPPKITYISLSSKQGN

Sequences:

>Translated_358_residues
MGARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSIDEVKPLAFLGYKVGMTHVIMIDDREHVDTAGQEIFVPVTVIETPP
MVVLGARVYGYDPNRGRYALTEVWRNPSDTIKEKLGEEVLRKYLLGMSKRLPHMVEELGPGKGFEFKVPEKELDVDPEKV
VGVGLIMSSIPFLAGGVSKKAPDILEVKVGGSPVEALEYAKGKLGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGV
KELPKWHKHRKGSRRVGARSWGKGTSSYVPQPGQMGYHRRTDYNKRVLMISDDPSKINVEGGWLHYGLVKSKYVVLKGSV
FGPPKRPIIMRLPVRPPAWVPPGPPKITYISLSSKQGN
>Mature_357_residues
GARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSIDEVKPLAFLGYKVGMTHVIMIDDREHVDTAGQEIFVPVTVIETPPM
VVLGARVYGYDPNRGRYALTEVWRNPSDTIKEKLGEEVLRKYLLGMSKRLPHMVEELGPGKGFEFKVPEKELDVDPEKVV
GVGLIMSSIPFLAGGVSKKAPDILEVKVGGSPVEALEYAKGKLGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGVK
ELPKWHKHRKGSRRVGARSWGKGTSSYVPQPGQMGYHRRTDYNKRVLMISDDPSKINVEGGWLHYGLVKSKYVVLKGSVF
GPPKRPIIMRLPVRPPAWVPPGPPKITYISLSSKQGN

Specific function: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit [H]

COG id: COG0087

COG function: function code J; Ribosomal protein L3

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L3P family [H]

Homologues:

Organism=Homo sapiens, GI4506649, Length=357, Percent_Identity=33.6134453781513, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI76496472, Length=357, Percent_Identity=32.4929971988796, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4826988, Length=358, Percent_Identity=31.2849162011173, Blast_Score=132, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71984538, Length=394, Percent_Identity=31.4720812182741, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71984544, Length=382, Percent_Identity=29.8429319371728, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71984550, Length=201, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324637, Length=350, Percent_Identity=32, Blast_Score=138, Evalue=1e-33,
Organism=Drosophila melanogaster, GI17737907, Length=389, Percent_Identity=31.6195372750643, Blast_Score=153, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24645877, Length=372, Percent_Identity=30.9139784946237, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645879, Length=372, Percent_Identity=30.9139784946237, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24645875, Length=126, Percent_Identity=39.6825396825397, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24645881, Length=117, Percent_Identity=36.7521367521368, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000597
- InterPro:   IPR019928
- InterPro:   IPR019926
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00297 Ribosomal_L3 [H]

EC number: NA

Molecular weight: Translated: 39627; Mature: 39496

Theoretical pI: Translated: 10.60; Mature: 10.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSIDEVKPLAFLGYKVGMTHVIMIDDRE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHEEECCEEEEEECCCH
HVDTAGQEIFVPVTVIETPPMVVLGARVYGYDPNRGRYALTEVWRNPSDTIKEKLGEEVL
HHCCCCCEEEEEEEEECCCCEEEEECEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
RKYLLGMSKRLPHMVEELGPGKGFEFKVPEKELDVDPEKVVGVGLIMSSIPFLAGGVSKK
HHHHHHHHHCCHHHHHHCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
APDILEVKVGGSPVEALEYAKGKLGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGV
CCCEEEEEECCCHHHHHHHHHCCCCCEECHHHHHHCCCEEEEEEECCCCCHHHHHHHCCH
KELPKWHKHRKGSRRVGARSWGKGTSSYVPQPGQMGYHRRTDYNKRVLMISDDPSKINVE
HHCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC
GGWLHYGLVKSKYVVLKGSVFGPPKRPIIMRLPVRPPAWVPPGPPKITYISLSSKQGN
CCEEEEEECCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCC
>Mature Secondary Structure 
GARKKEAPRRGSAGLRPRKRAASIVPRVRSWPSIDEVKPLAFLGYKVGMTHVIMIDDRE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHEEECCEEEEEECCCH
HVDTAGQEIFVPVTVIETPPMVVLGARVYGYDPNRGRYALTEVWRNPSDTIKEKLGEEVL
HHCCCCCEEEEEEEEECCCCEEEEECEEEECCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
RKYLLGMSKRLPHMVEELGPGKGFEFKVPEKELDVDPEKVVGVGLIMSSIPFLAGGVSKK
HHHHHHHHHCCHHHHHHCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
APDILEVKVGGSPVEALEYAKGKLGQLVDVEEVIEAGKFVDVIGVTKGKGFQGVIKRFGV
CCCEEEEEECCCHHHHHHHHHCCCCCEECHHHHHHCCCEEEEEEECCCCCHHHHHHHCCH
KELPKWHKHRKGSRRVGARSWGKGTSSYVPQPGQMGYHRRTDYNKRVLMISDDPSKINVE
HHCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEC
GGWLHYGLVKSKYVVLKGSVFGPPKRPIIMRLPVRPPAWVPPGPPKITYISLSSKQGN
CCEEEEEECCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]