Click here to switch to the map view.

The map label for this gene is 156937397

Identifier: 156937397

GI number: 156937397

Start: 540675

End: 541961

Strand: Direct

Name: 156937397

Synonym: Igni_0604

Alternate gene names: NA

Gene position: 540675-541961 (Clockwise)

Preceding gene: 156937395

Following gene: 156937401

Centisome position: 41.67

GC content: 58.82

Gene sequence:

>1287_bases
ATGGGCGCAGAGATAACTTTCTTGGGCGGCGCTAGGGAGGTGGGCAGAGCCGCTTATTGGGTCAAGGACGGCAAGGCGAG
TCTCCTCCTCGACTACGGGGTCAGCTTCGACGAAGAGGATAGGCCGGTGTTCCCGGAGTACGTGTCTCCCAAGGACGTGG
GCGCGGTGGTGCTCAGCCACGCCCACTTGGACCACTCCGGCGCGCTGCCGATGCTTTACTCCGCCATCCGCAGGCCTGCC
TACATGACAAAGCTGACCAAAGAGCTCACCGCGATACTGATAAACGACTTCTTGAAACTTTCGGGATACTACGCGACCTA
CGGAGAGACCGAAGTCAAGGAGTTCTTAGAATCCGTGAGGACCGTAGACTACAGGAGGACCGTGGAGATACCGGAGGCCG
GCGGGACCCTCTTGACCTTCTACGACGCCGGCCACATACCGGGCAGCGCAATGGTGAAGTTAGAGCTCCCCAGCGGCTTG
AAGCTGCTCTACACCGGCGACGTCAGGTTGAGCGAGACCCAGCTGCTGGGAGGGGCGGACGTCAGCGGCTTGGAAGCGGA
CGTGTTAATAATAGAAGCCACGTACGGGAAGTCCGACCATCCCCCCAGGGAGAACGTGGAGGCGCTGTTCGTCAGCGACG
TGAGGGAGGTTTTGCAGGGCGGCGGGACGGTACTCGTCCCGGCCTTCGGCGTAGGAAGGGGTCAAGAGATACTCGCGGTG
CTCGCGGACCACGAGGTGGAGGGAGACGTTTACCTAGACGGCATGGTGAGGAACGTAACCGAGCTCTTGATTCAAGGCGA
AAACAAAAAGTTCTTGAAAAATCCGGACATGCTAGAGAAAGCCTACGAGGAGGCCAAGGTGGTGAGGGGCTGGCAAGATA
GGAGGAGGGTGTGGAAGAGGAACGGCGTAATAATAGCTTCTGCCGGCATGCTCAGAGGCGGCCCATCTCTATATTACGCG
AGGAAGATCCAAGGGATCCCGAAGGACGCTATCTTCTTGGTGTCCTTCCAAGCACCCGGGACCCCCGGGCGCAGGTTAGT
GGAGGAAGGAGTCATCGAGGAGGGCGGACCCCGGGTGGAGGCGAGGACCCAGTGGTTCGACTTCTCCAGCCACGCGGGGG
CCAGCGAACTCTTGGAGATAATAAAGTCGGTCAACAAATTGAAGAAGGTTATAATAGTTCACTCAGAAGAGAGCACGGCC
CTCCACTTCGCGCAGAGGGTGAGGGAGGAGACGGGCCTCGACGTGATAGTTCCGAAACCAATGGAGACGCTGAAGGTCGA
AGTATAG

Upstream 100 bases:

>100_bases
GGCCTTCATGTTGAAGCCGAACGGGAGCACCGCGTTACCACCTCCCTTAAATTGCCTTCGTGAACCGGTCCAAAAGGGTT
TAGATAAGCGGTGATGGGGA

Downstream 100 bases:

>100_bases
CTACTTTTTATACAGCGGCTTCTTAACTTCGTGTACCTCGACTTCTAGGTCTTCCTTACCCACTTCTTTTTTTACGTTCT
CAAGCGTTTCGTCCAGCCTA

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MGAEITFLGGAREVGRAAYWVKDGKASLLLDYGVSFDEEDRPVFPEYVSPKDVGAVVLSHAHLDHSGALPMLYSAIRRPA
YMTKLTKELTAILINDFLKLSGYYATYGETEVKEFLESVRTVDYRRTVEIPEAGGTLLTFYDAGHIPGSAMVKLELPSGL
KLLYTGDVRLSETQLLGGADVSGLEADVLIIEATYGKSDHPPRENVEALFVSDVREVLQGGGTVLVPAFGVGRGQEILAV
LADHEVEGDVYLDGMVRNVTELLIQGENKKFLKNPDMLEKAYEEAKVVRGWQDRRRVWKRNGVIIASAGMLRGGPSLYYA
RKIQGIPKDAIFLVSFQAPGTPGRRLVEEGVIEEGGPRVEARTQWFDFSSHAGASELLEIIKSVNKLKKVIIVHSEESTA
LHFAQRVREETGLDVIVPKPMETLKVEV

Sequences:

>Translated_428_residues
MGAEITFLGGAREVGRAAYWVKDGKASLLLDYGVSFDEEDRPVFPEYVSPKDVGAVVLSHAHLDHSGALPMLYSAIRRPA
YMTKLTKELTAILINDFLKLSGYYATYGETEVKEFLESVRTVDYRRTVEIPEAGGTLLTFYDAGHIPGSAMVKLELPSGL
KLLYTGDVRLSETQLLGGADVSGLEADVLIIEATYGKSDHPPRENVEALFVSDVREVLQGGGTVLVPAFGVGRGQEILAV
LADHEVEGDVYLDGMVRNVTELLIQGENKKFLKNPDMLEKAYEEAKVVRGWQDRRRVWKRNGVIIASAGMLRGGPSLYYA
RKIQGIPKDAIFLVSFQAPGTPGRRLVEEGVIEEGGPRVEARTQWFDFSSHAGASELLEIIKSVNKLKKVIIVHSEESTA
LHFAQRVREETGLDVIVPKPMETLKVEV
>Mature_427_residues
GAEITFLGGAREVGRAAYWVKDGKASLLLDYGVSFDEEDRPVFPEYVSPKDVGAVVLSHAHLDHSGALPMLYSAIRRPAY
MTKLTKELTAILINDFLKLSGYYATYGETEVKEFLESVRTVDYRRTVEIPEAGGTLLTFYDAGHIPGSAMVKLELPSGLK
LLYTGDVRLSETQLLGGADVSGLEADVLIIEATYGKSDHPPRENVEALFVSDVREVLQGGGTVLVPAFGVGRGQEILAVL
ADHEVEGDVYLDGMVRNVTELLIQGENKKFLKNPDMLEKAYEEAKVVRGWQDRRRVWKRNGVIIASAGMLRGGPSLYYAR
KIQGIPKDAIFLVSFQAPGTPGRRLVEEGVIEEGGPRVEARTQWFDFSSHAGASELLEIIKSVNKLKKVIIVHSEESTAL
HFAQRVREETGLDVIVPKPMETLKVEV

Specific function: Unknown

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family [H]

Homologues:

Organism=Homo sapiens, GI7706427, Length=416, Percent_Identity=28.125, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI33300633, Length=450, Percent_Identity=26.4444444444444, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI32566029, Length=432, Percent_Identity=26.3888888888889, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32564696, Length=463, Percent_Identity=26.133909287257, Blast_Score=143, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323307, Length=427, Percent_Identity=25.5269320843091, Blast_Score=139, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24648013, Length=422, Percent_Identity=27.0142180094787, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21358523, Length=446, Percent_Identity=26.0089686098655, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 47131; Mature: 46999

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAEITFLGGAREVGRAAYWVKDGKASLLLDYGVSFDEEDRPVFPEYVSPKDVGAVVLSH
CCCEEEEECCCHHHCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
AHLDHSGALPMLYSAIRRPAYMTKLTKELTAILINDFLKLSGYYATYGETEVKEFLESVR
HCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
TVDYRRTVEIPEAGGTLLTFYDAGHIPGSAMVKLELPSGLKLLYTGDVRLSETQLLGGAD
HCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCEEEEEEEEECCCC
VSGLEADVLIIEATYGKSDHPPRENVEALFVSDVREVLQGGGTVLVPAFGVGRGQEILAV
CCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHE
LADHEVEGDVYLDGMVRNVTELLIQGENKKFLKNPDMLEKAYEEAKVVRGWQDRRRVWKR
EECCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
NGVIIASAGMLRGGPSLYYARKIQGIPKDAIFLVSFQAPGTPGRRLVEEGVIEEGGPRVE
CCEEEEECCCCCCCCCEEEEHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCE
ARTQWFDFSSHAGASELLEIIKSVNKLKKVIIVHSEESTALHFAQRVREETGLDVIVPKP
EEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCC
METLKVEV
HHHHEECC
>Mature Secondary Structure 
GAEITFLGGAREVGRAAYWVKDGKASLLLDYGVSFDEEDRPVFPEYVSPKDVGAVVLSH
CCEEEEECCCHHHCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
AHLDHSGALPMLYSAIRRPAYMTKLTKELTAILINDFLKLSGYYATYGETEVKEFLESVR
HCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
TVDYRRTVEIPEAGGTLLTFYDAGHIPGSAMVKLELPSGLKLLYTGDVRLSETQLLGGAD
HCCCCEEEECCCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEECCEEEEEEEEECCCC
VSGLEADVLIIEATYGKSDHPPRENVEALFVSDVREVLQGGGTVLVPAFGVGRGQEILAV
CCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHE
LADHEVEGDVYLDGMVRNVTELLIQGENKKFLKNPDMLEKAYEEAKVVRGWQDRRRVWKR
EECCCCCCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
NGVIIASAGMLRGGPSLYYARKIQGIPKDAIFLVSFQAPGTPGRRLVEEGVIEEGGPRVE
CCEEEEECCCCCCCCCEEEEHHHCCCCCCEEEEEEEECCCCCHHHHHHHCCCCCCCCCCE
ARTQWFDFSSHAGASELLEIIKSVNKLKKVIIVHSEESTALHFAQRVREETGLDVIVPKP
EEEEEECCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHCCCEEEECCC
METLKVEV
HHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]