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The map label for this gene is ctpA [H]

Identifier: 154686370

GI number: 154686370

Start: 2057110

End: 2058513

Strand: Reverse

Name: ctpA [H]

Synonym: RBAM_019380

Alternate gene names: 154686370

Gene position: 2058513-2057110 (Counterclockwise)

Preceding gene: 154686373

Following gene: 154686368

Centisome position: 52.53

GC content: 45.73

Gene sequence:

>1404_bases
TTGAAGCGGCAATTTAAACTGTTTTTTATTATATTGATCACTGCGGTCGCAGCCTCGTCGCTTACGCTGTTTATCACGGG
CAATACGACCATTTTCGGACAAGGCTCGGCTGCTTTGACGAACAGCAAATTTGAGAAATTCAATAAAGCCTACGAGCAGA
TTAAAAGTGATTACTATCAAAAAACAGATGACAGCAAATTAGTAGACGGAGCGATAAAAGGCATGATCAGTTCCCTGGAT
GATCCATATTCTTCTTATATGGACCCGCAGGAAGGAAAGTCTTTTGAAGAAACCATTTCCGCTTCGTTTGAAGGCATCGG
CGCACAAGTGGAAGAAAAGGACGGCAGTATCCTGATCGTATCGCCGATTAAAGGGTCACCCGCGGAAAAAGCGGGGGTTA
AACCGAATGACCAGATCTTGAAGGTCAACGGCAAAAGCGTTAAAGGCCTTAATGTAAACGAAGCCGTCGCATTAATCCGC
GGCAAAAAGGGAACAAACGTCAAGCTTGTGCTGCACAGAGCGGGTGTCGGCGATCTGAACCTGTCGATCAAACGTGACAC
CATCCCGGTTGAAACGGTGTACTCTGAAATGAAAAAAGGAGACATCGGCGAAATCCAAATCACATCCTTCTCCGAATCGA
CGGCAAAAGAGCTGAATTCAGCCATTGACAGCCTCGAAAAACAAGGAGCGAAAGGATACATTCTCGATTTAAGGGGCAAC
CCGGGCGGACTGATGGATGAAGCCATCAAAATGAGCAACATGTTTATCGATAAAGGGAAAAATATCATGCAGGTCGAATA
CAAAGACGGCACGAAAGAGGTCATGAAAGCGACGAAAGAGCGAAAAGTGACAAAACCGACAGTCGTCCTCGTCAATGACG
GCACCGCGAGCGCCGCGGAAATCATGTCGGCTGCGCTGCATGAATCATCGGGCATTCCGCTGATCGGCGAGAAAACGTTC
GGAAAAGGAACCGTGCAGACGGCAAAAGATTACAGCGACGGTTCTACCGTTAAACTGACAATCGCTAAATGGCTGACAGC
GGACGGAGAGTGGATTCATAAAAAAGGCATCAAACCGCAATATCAGGTTAAGCTTCCTGAATATGCGAACCTGCCGTATT
TAGATGCGAAAAAAACATACAAATACGGGGATTCCGGAACCACCGTCACCAATGCGCAAAAAATGCTGAAAGCGCTGGGG
TACAGCGTGAAAGTAAACGGCACGTATGATAAAGCATTTGAACAAGCCGTTAAACAATTCCAAGCAAAAGAGAAACTGAA
ACAAACAGGCATTATAACGGGTGACACAACGGCAAAATTGATGACGGATCTGCAAAAACAGCTTGCGGACAACGATACAC
AAATGAAAAAAGCCGTTGAAACACTAAATAAGAATATGAAATAG

Upstream 100 bases:

>100_bases
TAGGTTTGGGTAAACGGGAAAGAAGGGCGCCTCACGTTTGAAGTTGACGAATGAGCGTTCGTCTATGATAATAATGTAAG
AATAAAAAGGTGGTGTTTTC

Downstream 100 bases:

>100_bases
TAAAAAACACCCGATGCGCCGCTCGCGCATTGGGTGTTTTTTGTTTGCGAAAAGCCCATCTTATGTCGTTTCCTGTTCAA
AAAGGTGGCTGTTCGCCTGA

Product: CtpA

Products: NA

Alternate protein names: C-terminal processing protease [H]

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKRQFKLFFIILITAVAASSLTLFITGNTTIFGQGSAALTNSKFEKFNKAYEQIKSDYYQKTDDSKLVDGAIKGMISSLD
DPYSSYMDPQEGKSFEETISASFEGIGAQVEEKDGSILIVSPIKGSPAEKAGVKPNDQILKVNGKSVKGLNVNEAVALIR
GKKGTNVKLVLHRAGVGDLNLSIKRDTIPVETVYSEMKKGDIGEIQITSFSESTAKELNSAIDSLEKQGAKGYILDLRGN
PGGLMDEAIKMSNMFIDKGKNIMQVEYKDGTKEVMKATKERKVTKPTVVLVNDGTASAAEIMSAALHESSGIPLIGEKTF
GKGTVQTAKDYSDGSTVKLTIAKWLTADGEWIHKKGIKPQYQVKLPEYANLPYLDAKKTYKYGDSGTTVTNAQKMLKALG
YSVKVNGTYDKAFEQAVKQFQAKEKLKQTGIITGDTTAKLMTDLQKQLADNDTQMKKAVETLNKNMK

Sequences:

>Translated_467_residues
MKRQFKLFFIILITAVAASSLTLFITGNTTIFGQGSAALTNSKFEKFNKAYEQIKSDYYQKTDDSKLVDGAIKGMISSLD
DPYSSYMDPQEGKSFEETISASFEGIGAQVEEKDGSILIVSPIKGSPAEKAGVKPNDQILKVNGKSVKGLNVNEAVALIR
GKKGTNVKLVLHRAGVGDLNLSIKRDTIPVETVYSEMKKGDIGEIQITSFSESTAKELNSAIDSLEKQGAKGYILDLRGN
PGGLMDEAIKMSNMFIDKGKNIMQVEYKDGTKEVMKATKERKVTKPTVVLVNDGTASAAEIMSAALHESSGIPLIGEKTF
GKGTVQTAKDYSDGSTVKLTIAKWLTADGEWIHKKGIKPQYQVKLPEYANLPYLDAKKTYKYGDSGTTVTNAQKMLKALG
YSVKVNGTYDKAFEQAVKQFQAKEKLKQTGIITGDTTAKLMTDLQKQLADNDTQMKKAVETLNKNMK
>Mature_467_residues
MKRQFKLFFIILITAVAASSLTLFITGNTTIFGQGSAALTNSKFEKFNKAYEQIKSDYYQKTDDSKLVDGAIKGMISSLD
DPYSSYMDPQEGKSFEETISASFEGIGAQVEEKDGSILIVSPIKGSPAEKAGVKPNDQILKVNGKSVKGLNVNEAVALIR
GKKGTNVKLVLHRAGVGDLNLSIKRDTIPVETVYSEMKKGDIGEIQITSFSESTAKELNSAIDSLEKQGAKGYILDLRGN
PGGLMDEAIKMSNMFIDKGKNIMQVEYKDGTKEVMKATKERKVTKPTVVLVNDGTASAAEIMSAALHESSGIPLIGEKTF
GKGTVQTAKDYSDGSTVKLTIAKWLTADGEWIHKKGIKPQYQVKLPEYANLPYLDAKKTYKYGDSGTTVTNAQKMLKALG
YSVKVNGTYDKAFEQAVKQFQAKEKLKQTGIITGDTTAKLMTDLQKQLADNDTQMKKAVETLNKNMK

Specific function: Involved In The Cleavage Of A C-Terminal Peptide Of 11 Residues From The Precursor Form Of Penicillin-Binding Protein 3 (Pbp3). May Be Involved In Protection Of The Bacterium From Thermal And Osmotic Stresses. [C]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Associated With The Periplasmic Protein Side Of The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=305, Percent_Identity=32.4590163934426, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR002477 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41; PF01471 PG_binding_1 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 50938; Mature: 50938

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQFKLFFIILITAVAASSLTLFITGNTTIFGQGSAALTNSKFEKFNKAYEQIKSDYYQ
CCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
KTDDSKLVDGAIKGMISSLDDPYSSYMDPQEGKSFEETISASFEGIGAQVEEKDGSILIV
CCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEE
SPIKGSPAEKAGVKPNDQILKVNGKSVKGLNVNEAVALIRGKKGTNVKLVLHRAGVGDLN
ECCCCCCCHHCCCCCCCCEEEECCCEECCCCHHHHHHEEECCCCCCEEEEEEECCCCCEE
LSIKRDTIPVETVYSEMKKGDIGEIQITSFSESTAKELNSAIDSLEKQGAKGYILDLRGN
EEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PGGLMDEAIKMSNMFIDKGKNIMQVEYKDGTKEVMKATKERKVTKPTVVLVNDGTASAAE
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
IMSAALHESSGIPLIGEKTFGKGTVQTAKDYSDGSTVKLTIAKWLTADGEWIHKKGIKPQ
HHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCC
YQVKLPEYANLPYLDAKKTYKYGDSGTTVTNAQKMLKALGYSVKVNGTYDKAFEQAVKQF
EEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
QAKEKLKQTGIITGDTTAKLMTDLQKQLADNDTQMKKAVETLNKNMK
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRQFKLFFIILITAVAASSLTLFITGNTTIFGQGSAALTNSKFEKFNKAYEQIKSDYYQ
CCCCHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHC
KTDDSKLVDGAIKGMISSLDDPYSSYMDPQEGKSFEETISASFEGIGAQVEEKDGSILIV
CCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCEEEE
SPIKGSPAEKAGVKPNDQILKVNGKSVKGLNVNEAVALIRGKKGTNVKLVLHRAGVGDLN
ECCCCCCCHHCCCCCCCCEEEECCCEECCCCHHHHHHEEECCCCCCEEEEEEECCCCCEE
LSIKRDTIPVETVYSEMKKGDIGEIQITSFSESTAKELNSAIDSLEKQGAKGYILDLRGN
EEEECCCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCC
PGGLMDEAIKMSNMFIDKGKNIMQVEYKDGTKEVMKATKERKVTKPTVVLVNDGTASAAE
CCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
IMSAALHESSGIPLIGEKTFGKGTVQTAKDYSDGSTVKLTIAKWLTADGEWIHKKGIKPQ
HHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCHHHCCCCCC
YQVKLPEYANLPYLDAKKTYKYGDSGTTVTNAQKMLKALGYSVKVNGTYDKAFEQAVKQF
EEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHH
QAKEKLKQTGIITGDTTAKLMTDLQKQLADNDTQMKKAVETLNKNMK
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8996100; 9734814; 9384377 [H]