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The map label for this gene is bglA [H]

Identifier: 154686368

GI number: 154686368

Start: 2054632

End: 2056074

Strand: Reverse

Name: bglA [H]

Synonym: RBAM_019360

Alternate gene names: 154686368

Gene position: 2056074-2054632 (Counterclockwise)

Preceding gene: 154686370

Following gene: 154686367

Centisome position: 52.47

GC content: 44.01

Gene sequence:

>1443_bases
ATGGGGACATTGCCAAAAGATTTTTTATGGGGAGGCGCTCTGGCCGCCCACCAATTTGAAGGGGGATGGAATAAAGGCGG
CAAGGGGCCGAGTGTAGTGGACGTCATGACGGCAGGCGCGCATGGTGTGCCCCGGAAAATAACAGATACAATTGAAGAGC
GGGAATTTTATCCGAATCATGAAGCGATTGATTTTTATCATCGTTATAAAGAGGACATCGCATTATTCAGCGAGCTGGGT
CTGAAATGTTTAAGAACGTCCATCGGCTGGAGCAGAATTTTTCCTAAAGGTGATGAAGCCGAGCCCAATGAGGAAGGATT
GGCTTTTTACGACCGGGTGTTTGATGAATTGCTGAAACATGGGATTGAACCGGTAATCACGCTGTCACATTTTGAGATGC
CGCTGCATTTGGCGAGAGAATACGGCGGTTTCAGAAACAGAAAAACAGTCGGATTTTTTGTAAAATTCGCTGAAGTGTGT
TTTGAACGCTATAAACATAAGGTGAAGTATTGGATGACGTTTAACGAAATCAATAATAAGATGGATGTGAATAATCCGAT
CTTTTTATGGACGAACTCGGGCGTCGCCGTCAAAGAAAACGAAAACGCAAAAGAAGTCATGTATCAGGCCGGCCATCACG
AACTGCTGGCAAGCGCATTGGCTGTTTCGAAGGGAAGAGACATCAATCCTGAGTTCAGGATCGGCGCGATGGTATCACAT
GTTCCGATTTACCCGTACTCATCTCACCCCGACGATGTGATGCTGGCTGAAGAAACGATGAGACAACGTTTTTTCTTCCC
GGACGTGCAGGTTCGCGGATATTATCCAAGCTATGCGTTAAAAGAGTTTGAAAGAGAAGGCTATCAGATACACTTTGAAG
ACGGTGATGAAGAGATTTTGAAAAACGGCCGAGTGGACTACCTCGGATTCAGCTATTACATGTCTACAACCGTAAAAAGT
GATGTATCAAACGATAATACCGGGGATGTCGTAAACGGAGGATTGCCAAACGGCGTGGAAAATCCTTATATTACAGCGAG
TGATTGGGGCTGGGCGATTGACCCGACCGGTTTACGGTACACATTAAACCGCTTATACGACCGCTACCAGATTCCATTAT
TTATCGTGGAAAACGGATTCGGCGCCATCGACACATTAGAAGAGGACGGTTCAATTCATGACACTTCAAGAATTGAATAT
TTATCGTCACATATAAAAGCTTTGAAAAAAGCAATCACATATGATGGTGTGGATGTAATGGGCTATACACCATGGGGAAT
TATTGATATCGTGTCATTTACAACCGGAGAAATGAAAAAACGCTACGGCATGATTTATGTTGATCGGGATAATGAAGGCA
ACGGTTCAATGAGGCGGCTTAAGAAAGACTCATTTGAATGGTATAAAAAAGTGATTGAAACAAACGGCTCATATGTATCC
TAA

Upstream 100 bases:

>100_bases
AGGCAGGAATTCTTCTGCACTTGCGAAGCGGATGCTTGTAGCGGCTGCAGTGCATTTATTCGGCATGCAAGCGGCAGTCA
AATAAAGGAGGATATAAACG

Downstream 100 bases:

>100_bases
AGGTGTAAAAAGGGAAGGCTTCACCGTTGTGTGAAGCCGGCTTTTTATCAGTAATTTTGAAAGCGTATTCATTTAAGCGG
GAAGGAGGTGACTGTCCGGC

Product: BglA

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 480; Mature: 479

Protein sequence:

>480_residues
MGTLPKDFLWGGALAAHQFEGGWNKGGKGPSVVDVMTAGAHGVPRKITDTIEEREFYPNHEAIDFYHRYKEDIALFSELG
LKCLRTSIGWSRIFPKGDEAEPNEEGLAFYDRVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKTVGFFVKFAEVC
FERYKHKVKYWMTFNEINNKMDVNNPIFLWTNSGVAVKENENAKEVMYQAGHHELLASALAVSKGRDINPEFRIGAMVSH
VPIYPYSSHPDDVMLAEETMRQRFFFPDVQVRGYYPSYALKEFEREGYQIHFEDGDEEILKNGRVDYLGFSYYMSTTVKS
DVSNDNTGDVVNGGLPNGVENPYITASDWGWAIDPTGLRYTLNRLYDRYQIPLFIVENGFGAIDTLEEDGSIHDTSRIEY
LSSHIKALKKAITYDGVDVMGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMRRLKKDSFEWYKKVIETNGSYVS

Sequences:

>Translated_480_residues
MGTLPKDFLWGGALAAHQFEGGWNKGGKGPSVVDVMTAGAHGVPRKITDTIEEREFYPNHEAIDFYHRYKEDIALFSELG
LKCLRTSIGWSRIFPKGDEAEPNEEGLAFYDRVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKTVGFFVKFAEVC
FERYKHKVKYWMTFNEINNKMDVNNPIFLWTNSGVAVKENENAKEVMYQAGHHELLASALAVSKGRDINPEFRIGAMVSH
VPIYPYSSHPDDVMLAEETMRQRFFFPDVQVRGYYPSYALKEFEREGYQIHFEDGDEEILKNGRVDYLGFSYYMSTTVKS
DVSNDNTGDVVNGGLPNGVENPYITASDWGWAIDPTGLRYTLNRLYDRYQIPLFIVENGFGAIDTLEEDGSIHDTSRIEY
LSSHIKALKKAITYDGVDVMGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMRRLKKDSFEWYKKVIETNGSYVS
>Mature_479_residues
GTLPKDFLWGGALAAHQFEGGWNKGGKGPSVVDVMTAGAHGVPRKITDTIEEREFYPNHEAIDFYHRYKEDIALFSELGL
KCLRTSIGWSRIFPKGDEAEPNEEGLAFYDRVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKTVGFFVKFAEVCF
ERYKHKVKYWMTFNEINNKMDVNNPIFLWTNSGVAVKENENAKEVMYQAGHHELLASALAVSKGRDINPEFRIGAMVSHV
PIYPYSSHPDDVMLAEETMRQRFFFPDVQVRGYYPSYALKEFEREGYQIHFEDGDEEILKNGRVDYLGFSYYMSTTVKSD
VSNDNTGDVVNGGLPNGVENPYITASDWGWAIDPTGLRYTLNRLYDRYQIPLFIVENGFGAIDTLEEDGSIHDTSRIEYL
SSHIKALKKAITYDGVDVMGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMRRLKKDSFEWYKKVIETNGSYVS

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=499, Percent_Identity=27.4549098196393, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI110681710, Length=502, Percent_Identity=28.4860557768924, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI13273313, Length=490, Percent_Identity=27.1428571428571, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI24497614, Length=493, Percent_Identity=27.9918864097363, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI28376633, Length=490, Percent_Identity=26.3265306122449, Blast_Score=140, Evalue=4e-33,
Organism=Escherichia coli, GI2367174, Length=474, Percent_Identity=65.4008438818565, Blast_Score=670, Evalue=0.0,
Organism=Escherichia coli, GI1789070, Length=482, Percent_Identity=50.6224066390041, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI2367270, Length=476, Percent_Identity=50, Blast_Score=459, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17552856, Length=486, Percent_Identity=30.4526748971193, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17539390, Length=503, Percent_Identity=28.0318091451292, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI21356577, Length=501, Percent_Identity=27.3453093812375, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54965; Mature: 54834

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTLPKDFLWGGALAAHQFEGGWNKGGKGPSVVDVMTAGAHGVPRKITDTIEEREFYPNH
CCCCCCHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC
EAIDFYHRYKEDIALFSELGLKCLRTSIGWSRIFPKGDEAEPNEEGLAFYDRVFDELLKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GIEPVITLSHFEMPLHLAREYGGFRNRKTVGFFVKFAEVCFERYKHKVKYWMTFNEINNK
CCCEEEEEHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCC
MDVNNPIFLWTNSGVAVKENENAKEVMYQAGHHELLASALAVSKGRDINPEFRIGAMVSH
CCCCCCEEEEECCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHC
VPIYPYSSHPDDVMLAEETMRQRFFFPDVQVRGYYPSYALKEFEREGYQIHFEDGDEEIL
CCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEECCCHHHHH
KNGRVDYLGFSYYMSTTVKSDVSNDNTGDVVNGGLPNGVENPYITASDWGWAIDPTGLRY
HCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHH
TLNRLYDRYQIPLFIVENGFGAIDTLEEDGSIHDTSRIEYLSSHIKALKKAITYDGVDVM
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
GYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMRRLKKDSFEWYKKVIETNGSYVS
CCCCCCHHHHHHCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GTLPKDFLWGGALAAHQFEGGWNKGGKGPSVVDVMTAGAHGVPRKITDTIEEREFYPNH
CCCCCHHHHCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCC
EAIDFYHRYKEDIALFSELGLKCLRTSIGWSRIFPKGDEAEPNEEGLAFYDRVFDELLKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
GIEPVITLSHFEMPLHLAREYGGFRNRKTVGFFVKFAEVCFERYKHKVKYWMTFNEINNK
CCCEEEEEHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEHHHCCCC
MDVNNPIFLWTNSGVAVKENENAKEVMYQAGHHELLASALAVSKGRDINPEFRIGAMVSH
CCCCCCEEEEECCCEEEECCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHC
VPIYPYSSHPDDVMLAEETMRQRFFFPDVQVRGYYPSYALKEFEREGYQIHFEDGDEEIL
CCCCCCCCCCCCEEEHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCEEEECCCHHHHH
KNGRVDYLGFSYYMSTTVKSDVSNDNTGDVVNGGLPNGVENPYITASDWGWAIDPTGLRY
HCCCEEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHH
TLNRLYDRYQIPLFIVENGFGAIDTLEEDGSIHDTSRIEYLSSHIKALKKAITYDGVDVM
HHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEE
GYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMRRLKKDSFEWYKKVIETNGSYVS
CCCCCCHHHHHHCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8125345; 9384377 [H]