Click here to switch to the map view.

The map label for this gene is dppB [H]

Identifier: 154248578

GI number: 154248578

Start: 5149593

End: 5150606

Strand: Reverse

Name: dppB [H]

Synonym: Xaut_4659

Alternate gene names: 154248578

Gene position: 5150606-5149593 (Counterclockwise)

Preceding gene: 154248579

Following gene: 154248577

Centisome position: 97.02

GC content: 67.36

Gene sequence:

>1014_bases
ATGCTGAAGCTCATAGGCAGTCGTCTTGCCACCGCCGTGCCGAGCCTCATCGGCGTGGTGATCGTCACCTTCATGCTCAC
GCGGGTGCTGCCGGGTGACACCGCGGCCTATTTCGCCGGCCCCGCCGCTACGGCCGAATCCATCGCCGAGATCCGCACTA
AGCTCGGCCTCGACAAGCCGCTGCCGGCGCAGTTCGTGGACTATGTCTCGGCGCTGGCGAAGGGGGATCTGGGAAGCTCG
CTTTCCACCGGACAGCCGGTGGCGGCGGAGATTTCCGCGCGGCTTCCGGCCTCCGCCGAGCTGACGCTGGCGGGGCTGGT
GCTGGCGCTGGCCATCGCGGTGCCGTTCGGCATCATGGCGGCGGTGAAGCAGGGGTCCTGGGTGGATCATGCCTGCCGGC
TCATCACCACGGCGGGCGTGTCGCTGCCGGTGTTCTTCACCGGCTTGCTGCTGGTCTATGTGTTCTACTTCAAGCTCGGC
TGGGCCCCGGCGCCGCTGGGGCGGCTCGACGTGTTCTTCTCGGCGCCCGAGACCGTCACCGGCTTCTATCTCATCGACAG
CCTGATCGCGCGGGACTTCGAGACCTTCCGCGCCGCGCTGGCGCAGCTTGCGGTGCCGGCCATCACGCTCGCCATCTTCG
CGCTGGCGCCCATCGCCCGCATGACGCGCGCCTCCATGCTGTCGGTCTTGTCTTCAGAGTTCGTGCGCACGGCGCGGGCG
GCGGGGCTGACCGATACCACGGTGATCATCACCTACGCATTCCGCAACGCCATGCTGCCGGTGGTGACCACGCTGGGCAT
GGTGTTTTCCTTCCTGCTCGGCGCCAACGTGCTGGTGGAGAAGGTGTTCGCCTGGCCCGGCATCGGCTCCTACGCGGTGG
AGGCGCTGATCACCTCCGACTACGCGCCGGTGCAGGGCTTCGTGCTCGCCATGGCGATCCTCTACGTGGTCCTCAACCTC
CTGATCGATATCGCCTACGGCATCATCGACCCCCGCGCGCGGAGCGAAGCATGA

Upstream 100 bases:

>100_bases
TGACGGGGTGAGACGTTTTGGGAGAAAGGCCGGCGGGGCCATGGGCGGTTCTCGCCCTGGGACAACAGGCGGCCCCGGCC
TTCGGACAACAGGAGACACC

Downstream 100 bases:

>100_bases
CCCTCGCCACGGCCGACACCCCCGCCCCCCGCGGCCTTGCCGCGACCCTTGCCCACGCGCGCTACGTCATCTCCGACAAC
CCGGTCACCGGCATCGCCTT

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLKLIGSRLATAVPSLIGVVIVTFMLTRVLPGDTAAYFAGPAATAESIAEIRTKLGLDKPLPAQFVDYVSALAKGDLGSS
LSTGQPVAAEISARLPASAELTLAGLVLALAIAVPFGIMAAVKQGSWVDHACRLITTAGVSLPVFFTGLLLVYVFYFKLG
WAPAPLGRLDVFFSAPETVTGFYLIDSLIARDFETFRAALAQLAVPAITLAIFALAPIARMTRASMLSVLSSEFVRTARA
AGLTDTTVIITYAFRNAMLPVVTTLGMVFSFLLGANVLVEKVFAWPGIGSYAVEALITSDYAPVQGFVLAMAILYVVLNL
LIDIAYGIIDPRARSEA

Sequences:

>Translated_337_residues
MLKLIGSRLATAVPSLIGVVIVTFMLTRVLPGDTAAYFAGPAATAESIAEIRTKLGLDKPLPAQFVDYVSALAKGDLGSS
LSTGQPVAAEISARLPASAELTLAGLVLALAIAVPFGIMAAVKQGSWVDHACRLITTAGVSLPVFFTGLLLVYVFYFKLG
WAPAPLGRLDVFFSAPETVTGFYLIDSLIARDFETFRAALAQLAVPAITLAIFALAPIARMTRASMLSVLSSEFVRTARA
AGLTDTTVIITYAFRNAMLPVVTTLGMVFSFLLGANVLVEKVFAWPGIGSYAVEALITSDYAPVQGFVLAMAILYVVLNL
LIDIAYGIIDPRARSEA
>Mature_337_residues
MLKLIGSRLATAVPSLIGVVIVTFMLTRVLPGDTAAYFAGPAATAESIAEIRTKLGLDKPLPAQFVDYVSALAKGDLGSS
LSTGQPVAAEISARLPASAELTLAGLVLALAIAVPFGIMAAVKQGSWVDHACRLITTAGVSLPVFFTGLLLVYVFYFKLG
WAPAPLGRLDVFFSAPETVTGFYLIDSLIARDFETFRAALAQLAVPAITLAIFALAPIARMTRASMLSVLSSEFVRTARA
AGLTDTTVIITYAFRNAMLPVVTTLGMVFSFLLGANVLVEKVFAWPGIGSYAVEALITSDYAPVQGFVLAMAILYVVLNL
LIDIAYGIIDPRARSEA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=40.2941176470588, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787761, Length=315, Percent_Identity=43.1746031746032, Blast_Score=234, Evalue=4e-63,
Organism=Escherichia coli, GI1787053, Length=336, Percent_Identity=36.3095238095238, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789888, Length=339, Percent_Identity=33.9233038348083, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787497, Length=336, Percent_Identity=30.6547619047619, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787550, Length=276, Percent_Identity=31.1594202898551, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788504, Length=310, Percent_Identity=26.7741935483871, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35570; Mature: 35570

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLIGSRLATAVPSLIGVVIVTFMLTRVLPGDTAAYFAGPAATAESIAEIRTKLGLDKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCC
LPAQFVDYVSALAKGDLGSSLSTGQPVAAEISARLPASAELTLAGLVLALAIAVPFGIMA
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVKQGSWVDHACRLITTAGVSLPVFFTGLLLVYVFYFKLGWAPAPLGRLDVFFSAPETVT
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCHHH
GFYLIDSLIARDFETFRAALAQLAVPAITLAIFALAPIARMTRASMLSVLSSEFVRTARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLTDTTVIITYAFRNAMLPVVTTLGMVFSFLLGANVLVEKVFAWPGIGSYAVEALITSD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
YAPVQGFVLAMAILYVVLNLLIDIAYGIIDPRARSEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLKLIGSRLATAVPSLIGVVIVTFMLTRVLPGDTAAYFAGPAATAESIAEIRTKLGLDKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCC
LPAQFVDYVSALAKGDLGSSLSTGQPVAAEISARLPASAELTLAGLVLALAIAVPFGIMA
CCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AVKQGSWVDHACRLITTAGVSLPVFFTGLLLVYVFYFKLGWAPAPLGRLDVFFSAPETVT
HHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEECCCCHHH
GFYLIDSLIARDFETFRAALAQLAVPAITLAIFALAPIARMTRASMLSVLSSEFVRTARA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGLTDTTVIITYAFRNAMLPVVTTLGMVFSFLLGANVLVEKVFAWPGIGSYAVEALITSD
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCC
YAPVQGFVLAMAILYVVLNLLIDIAYGIIDPRARSEA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]