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The map label for this gene is pyrH

Identifier: 154248357

GI number: 154248357

Start: 4923074

End: 4923847

Strand: Reverse

Name: pyrH

Synonym: Xaut_4437

Alternate gene names: 154248357

Gene position: 4923847-4923074 (Counterclockwise)

Preceding gene: 154248358

Following gene: 154248356

Centisome position: 92.75

GC content: 71.19

Gene sequence:

>774_bases
ATGACCGCTTCCACGGCGGACGACTCGGACTTCCCGGAGCCCCCGGTGCCGTTCGCGGCATCGGGCCTCCCTTATCCCCG
CATCCTGGTGAAGGTCTCCGGCGAAGCCCTGATGGGCTCGGAGCCCTTCGGCCTCCATCCGCCTACCGTGGCCCGCATCG
CCCGTGACCTGGTCGCGGCGCGTGCGCTTGGCTGCGAGGTGGCGGTGGTGGTGGGCGGCGGCAACATCCTGCGCGGCGCG
CGGGTGGCGGGCGAGGATCTCGACCGCGCCACCGCCGACCACATGGGCATGCTGGCCACCGTCATGAACGGCCTCGCGCT
CGAGGCCGCCATCGAGGCGGCGGGCGCGCCGGCCCGCACCCTGTCCGCCATTCCCATGCCGACTGTCTGTGAGCCCTATG
CCCGCCAGCCGGCTAACCGGCACCTGCGGCGCGGGCGCATCGTCGTGCTCACCGGCGGCACCGGCAATCCGTATTTCACC
ACGGATACCGGCGCGGTCCTGCGCGCCGCCGAGCTGGATTGCGACGCGGTGCTGAAGGCCACTAACGTGGACGGTGTCTA
CACCGCCGACCCCAAGAAGGACCCGACCGCCACGCGCTACGACCGCATCACCCACGACGAGGCGCTCGCCCGCGACCTCA
AGGTGATGGATGCGGCCGCCTTCGCCCTTGCCCGCGAGGCGTCGTTGCCGATAATCGTGTTCGATATTCGCGAGCCCGGC
GCCATCGCCACGGCCGCGAAGGGTGAAGGCCGTGTGACGGTCGTCGCTCCCTGA

Upstream 100 bases:

>100_bases
TCACGGGAAGCGCTCTAGAGACTCGTGCTGACGCGTTTTCTTCACGCGAGCCGGTATCCACGCCGCTCGAAAACGCTCTA
AAGGGCAAAGGGGGGCTCTC

Downstream 100 bases:

>100_bases
ACCTGTACTGCGCGGGGCGATTACGCTTCTGCGCATTGTCGGGTCAAGGGGTGCCGGTCGTCGGCTGGGATCTTGGGTTG
GGGTTCAGGCTGGAATCGGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTASTADDSDFPEPPVPFAASGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARDLVAARALGCEVAVVVGGGNILRGA
RVAGEDLDRATADHMGMLATVMNGLALEAAIEAAGAPARTLSAIPMPTVCEPYARQPANRHLRRGRIVVLTGGTGNPYFT
TDTGAVLRAAELDCDAVLKATNVDGVYTADPKKDPTATRYDRITHDEALARDLKVMDAAAFALAREASLPIIVFDIREPG
AIATAAKGEGRVTVVAP

Sequences:

>Translated_257_residues
MTASTADDSDFPEPPVPFAASGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARDLVAARALGCEVAVVVGGGNILRGA
RVAGEDLDRATADHMGMLATVMNGLALEAAIEAAGAPARTLSAIPMPTVCEPYARQPANRHLRRGRIVVLTGGTGNPYFT
TDTGAVLRAAELDCDAVLKATNVDGVYTADPKKDPTATRYDRITHDEALARDLKVMDAAAFALAREASLPIIVFDIREPG
AIATAAKGEGRVTVVAP
>Mature_256_residues
TASTADDSDFPEPPVPFAASGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARDLVAARALGCEVAVVVGGGNILRGAR
VAGEDLDRATADHMGMLATVMNGLALEAAIEAAGAPARTLSAIPMPTVCEPYARQPANRHLRRGRIVVLTGGTGNPYFTT
DTGAVLRAAELDCDAVLKATNVDGVYTADPKKDPTATRYDRITHDEALARDLKVMDAAAFALAREASLPIIVFDIREPGA
IATAAKGEGRVTVVAP

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=231, Percent_Identity=51.9480519480519, Blast_Score=247, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26734; Mature: 26603

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASTADDSDFPEPPVPFAASGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARDLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHH
RALGCEVAVVVGGGNILRGARVAGEDLDRATADHMGMLATVMNGLALEAAIEAAGAPART
HHCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
LSAIPMPTVCEPYARQPANRHLRRGRIVVLTGGTGNPYFTTDTGAVLRAAELDCDAVLKA
HCCCCCCCCCCHHHCCCHHHHHHCCEEEEEECCCCCCCEECCCCCEEEEECCCHHHHEEE
TNVDGVYTADPKKDPTATRYDRITHDEALARDLKVMDAAAFALAREASLPIIVFDIREPG
CCCCCEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
AIATAAKGEGRVTVVAP
CEEEECCCCCEEEEECC
>Mature Secondary Structure 
TASTADDSDFPEPPVPFAASGLPYPRILVKVSGEALMGSEPFGLHPPTVARIARDLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCHHHHHHHHHHHHH
RALGCEVAVVVGGGNILRGARVAGEDLDRATADHMGMLATVMNGLALEAAIEAAGAPART
HHCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHH
LSAIPMPTVCEPYARQPANRHLRRGRIVVLTGGTGNPYFTTDTGAVLRAAELDCDAVLKA
HCCCCCCCCCCHHHCCCHHHHHHCCEEEEEECCCCCCCEECCCCCEEEEECCCHHHHEEE
TNVDGVYTADPKKDPTATRYDRITHDEALARDLKVMDAAAFALAREASLPIIVFDIREPG
CCCCCEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
AIATAAKGEGRVTVVAP
CEEEECCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA