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The map label for this gene is tsf

Identifier: 154248358

GI number: 154248358

Start: 4923991

End: 4924914

Strand: Reverse

Name: tsf

Synonym: Xaut_4438

Alternate gene names: 154248358

Gene position: 4924914-4923991 (Counterclockwise)

Preceding gene: 154248359

Following gene: 154248357

Centisome position: 92.77

GC content: 68.07

Gene sequence:

>924_bases
ATGGCTGCGATCACCGCCGGGCTGGTGAAGGAACTGCGCGACAAGACCGGCGCAGGCATGATGGATTGCAAGTCTGCGCT
CACCGAGACGAACGGCGACATCGAGGCCGCCATCGACTGGCTGCGCAAGAAGGGCCTCGCCAAGGCCGCCAAGAAGGCTG
GCCGCGTGGCTGCCGAGGGCCTGGTGGCGGTGGAATCCTCCGGCCACTACGCCGCCGCCATCGAAGTGAATGCGGAAACC
GACTTCGTCGCCCGCAACCCCGACTTCCAGGCGTTCGTGCGCGAGGCGGCCAAGGTCGCCCTCAACACCGACGGCACCGT
GGAAGCCGTGGCCGCCGCCAAGTTCCCCGGCGAGAGCGTCACCGTCGCCGAGCGCCTGACCGCGCTCATCGCCACCATCG
GCGAGAACATGACGCTGCGCCGCTCGGCCAAGCTCTCCGTGTCGGCCGGCGTCATCGCCAGCTACGTGCACGGCGCGGTG
GTGGAAGGCCAGGGCCGTATCGGCGTGCTGGTAGCGCTCGAGTCCACCGGCGACGTGGAGAAGCTCTCTACCCTCGGCCG
CCAGATCGCCATGCACATCGCCGCGCTGAACCCGCTGGCTCTGGACGCGTCCGGCATCTCCGAGGAGACCATCGCCCGCG
AGAAGGCCATCCTGCTCGAGAAGCACCAGGGCAAGCCCGCCAACGTGCAGGACAAGATCGCCGAGAGCGGCATCAAGAGC
TTCTTCAAGGAGGTCACCCTCCTCGACCAGGCCTTCGTGCATGACGGCTCCAAGTCGGTCTCCCAGGTTCTGAAGGAGGC
TGAGGGCCAGGTCGGCGCACCGCTCAAGCTCACCGGCTTCGTGCGCTTCGCGCTGGGCGAGGGCATCGAGAAGGAAGAGA
CGGACTTCGCCGCCGAGGTGGCTGCCGCCGCCGGCCAGTCCTGA

Upstream 100 bases:

>100_bases
TCTGATAGCGAATCGAGAGTAATGGGGCGCCTGGGGCGCCCCCACGGCCGGCTCGGGCACCCCCTGGCCGGCCGTGGCGC
GAGAAGAAGGGATTTTTGAC

Downstream 100 bases:

>100_bases
TCGACGTCCGCTTCTGACAAGAGCGCTTTCCGTTCGCCCCGGCTCACGGGAAGCGCTCTAGAGACTCGTGCTGACGCGTT
TTCTTCACGCGAGCCGGTAT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MAAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEGLVAVESSGHYAAAIEVNAET
DFVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESVTVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAV
VEGQGRIGVLVALESTGDVEKLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKS
FFKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEVAAAAGQS

Sequences:

>Translated_307_residues
MAAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEGLVAVESSGHYAAAIEVNAET
DFVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESVTVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAV
VEGQGRIGVLVALESTGDVEKLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKS
FFKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEVAAAAGQS
>Mature_306_residues
AAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEGLVAVESSGHYAAAIEVNAETD
FVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESVTVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAVV
EGQGRIGVLVALESTGDVEKLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKSF
FKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEVAAAAGQS

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=243, Percent_Identity=32.0987654320988, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI291084500, Length=264, Percent_Identity=30.6818181818182, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI291084502, Length=94, Percent_Identity=43.6170212765958, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI291084498, Length=94, Percent_Identity=43.6170212765958, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786366, Length=309, Percent_Identity=47.2491909385113, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17561440, Length=297, Percent_Identity=29.6296296296296, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921466, Length=305, Percent_Identity=29.1803278688525, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_XANP2 (A7INR5)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419316.1
- ProteinModelPortal:   A7INR5
- SMR:   A7INR5
- STRING:   A7INR5
- GeneID:   5424423
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4438
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- ProtClustDB:   PRK09377
- BioCyc:   XAUT78245:XAUT_4438-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31941; Mature: 31809

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEG
CCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCC
LVAVESSGHYAAAIEVNAETDFVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESV
EEEEECCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCH
TVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAVVEGQGRIGVLVALESTGDVE
HHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCEEEECCCCEEEEEEECCCCCHH
KLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKS
HHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FFKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHH
AAAAGQS
HHHCCCC
>Mature Secondary Structure 
AAITAGLVKELRDKTGAGMMDCKSALTETNGDIEAAIDWLRKKGLAKAAKKAGRVAAEG
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCC
LVAVESSGHYAAAIEVNAETDFVARNPDFQAFVREAAKVALNTDGTVEAVAAAKFPGESV
EEEEECCCCEEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCH
TVAERLTALIATIGENMTLRRSAKLSVSAGVIASYVHGAVVEGQGRIGVLVALESTGDVE
HHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHCEEEECCCCEEEEEEECCCCCHH
KLSTLGRQIAMHIAALNPLALDASGISEETIAREKAILLEKHQGKPANVQDKIAESGIKS
HHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
FFKEVTLLDQAFVHDGSKSVSQVLKEAEGQVGAPLKLTGFVRFALGEGIEKEETDFAAEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHH
AAAAGQS
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA