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The map label for this gene is frr

Identifier: 154248356

GI number: 154248356

Start: 4922167

End: 4922730

Strand: Reverse

Name: frr

Synonym: Xaut_4436

Alternate gene names: 154248356

Gene position: 4922730-4922167 (Counterclockwise)

Preceding gene: 154248357

Following gene: 154248355

Centisome position: 92.73

GC content: 64.89

Gene sequence:

>564_bases
ATGACCACCGGGACCTTCGACATGTCCGATCTGAAGCGCCGCATGCAGGGCGCTGTCGGCGTGCTCAGGGACGAACTGGG
CGGGCTGCGCACCGGGCGCGCCTCCGCCAGCCTGCTCGACCCCATCACCATCGAGGCCTACGGCGCGCGCATGCCGCTGA
ATCAGGTCGCCACCGTATCGGTGCCGGAAGCGCGCCTGCTGTCGGTGCAGGTGTGGGACCGCGGCATGGTGAGCGCGGTT
GAGAAAGCCATCCGCGACAGCAACCTTGGCCTCAACCCGAACACCGAGGGCCAGGTGCTGCGCCTGCGCATTCCCGAGCT
GAACCAGGAGCGTCGCCAGGAGCTGGTGAAGGTCGCCCACAAATATGCCGAGGCGGCCAAGGTGGCGGTGCGGCATGTGC
GTCGCGACGGTATGGACCACCTGAAGAAGGTGGAAAAGGACGGCGAGATGAGTTCCGATGATCTCGACCGCCTGTCCAAG
GACGTGCAGAAGGCCACCGACGAAACCATCGCCGAGATCGACCAGACGCTCGCCCAGAAGGAAAAGGAAATCCTTTCGGT
TTGA

Upstream 100 bases:

>100_bases
GAGCTCCGCATCCTGACGCGGGGTTCGGCCATTGGCATGGAAACAGAAACGTTTCCATGCCAATGGAGCGGGCCCCGACA
ACAGACTACAGAGGTTAGCC

Downstream 100 bases:

>100_bases
GGAGCCGCTCTTGAGCCCGGAGCAAGCCATGTCCCTACGCGCCGCTGCGGGCGAGGCCACCGTTACCGAACGGTCGCCGG
CTGTCGTCCCGGTGCATGTG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MTTGTFDMSDLKRRMQGAVGVLRDELGGLRTGRASASLLDPITIEAYGARMPLNQVATVSVPEARLLSVQVWDRGMVSAV
EKAIRDSNLGLNPNTEGQVLRLRIPELNQERRQELVKVAHKYAEAAKVAVRHVRRDGMDHLKKVEKDGEMSSDDLDRLSK
DVQKATDETIAEIDQTLAQKEKEILSV

Sequences:

>Translated_187_residues
MTTGTFDMSDLKRRMQGAVGVLRDELGGLRTGRASASLLDPITIEAYGARMPLNQVATVSVPEARLLSVQVWDRGMVSAV
EKAIRDSNLGLNPNTEGQVLRLRIPELNQERRQELVKVAHKYAEAAKVAVRHVRRDGMDHLKKVEKDGEMSSDDLDRLSK
DVQKATDETIAEIDQTLAQKEKEILSV
>Mature_186_residues
TTGTFDMSDLKRRMQGAVGVLRDELGGLRTGRASASLLDPITIEAYGARMPLNQVATVSVPEARLLSVQVWDRGMVSAVE
KAIRDSNLGLNPNTEGQVLRLRIPELNQERRQELVKVAHKYAEAAKVAVRHVRRDGMDHLKKVEKDGEMSSDDLDRLSKD
VQKATDETIAEIDQTLAQKEKEILSV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=32.4175824175824, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI291042689, Length=157, Percent_Identity=36.3057324840764, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=47.2527472527472, Blast_Score=161, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24661488, Length=181, Percent_Identity=27.0718232044199, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_XANP2 (A7INR3)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001419314.1
- ProteinModelPortal:   A7INR3
- SMR:   A7INR3
- STRING:   A7INR3
- GeneID:   5423626
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_4436
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   XAUT78245:XAUT_4436-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20775; Mature: 20644

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGTFDMSDLKRRMQGAVGVLRDELGGLRTGRASASLLDPITIEAYGARMPLNQVATVS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEHHHCCCCCCHHHHHCCC
VPEARLLSVQVWDRGMVSAVEKAIRDSNLGLNPNTEGQVLRLRIPELNQERRQELVKVAH
CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEAAKVAVRHVRRDGMDHLKKVEKDGEMSSDDLDRLSKDVQKATDETIAEIDQTLAQK
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEILSV
HHHHHCC
>Mature Secondary Structure 
TTGTFDMSDLKRRMQGAVGVLRDELGGLRTGRASASLLDPITIEAYGARMPLNQVATVS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCEEHHHCCCCCCHHHHHCCC
VPEARLLSVQVWDRGMVSAVEKAIRDSNLGLNPNTEGQVLRLRIPELNQERRQELVKVAH
CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
KYAEAAKVAVRHVRRDGMDHLKKVEKDGEMSSDDLDRLSKDVQKATDETIAEIDQTLAQK
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEILSV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA