| Definition | Xanthobacter autotrophicus Py2 chromosome, complete genome. |
|---|---|
| Accession | NC_009720 |
| Length | 5,308,934 |
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The map label for this gene is comEC [H]
Identifier: 154248290
GI number: 154248290
Start: 4845171
End: 4847444
Strand: Direct
Name: comEC [H]
Synonym: Xaut_4370
Alternate gene names: 154248290
Gene position: 4845171-4847444 (Clockwise)
Preceding gene: 154248287
Following gene: 154248300
Centisome position: 91.26
GC content: 72.52
Gene sequence:
>2274_bases ATGACGCAGCAGGACCAGCGTCCGGCGCGGACCAGCGGACGGGCCGCCGTTCTCGGCGGCGCGCGCACCGCCGCGCGCCG GGCGATGCCCCCCGGCCTCGCCCGCGTGCTGGATGCCCTGCGCGCCCGCCTCGCCGCGGATCTTGCCGCCGAGGCCGCCT CCGGCCGGTTGATCCTCTGGCTTCCGGCGGCATTCACCCTTGGCATCCTCATCTACTTCGGGGCGGCGCAGGAGCCGTCC CTTGCCGTCGCCGGGGTGCTTTTGGCCGCTCTTTGCGGGGGCGCGGTGCTGCTGCGGGCGCGACCGGTGGCGTTCGGCGC GATGGTGGCCCTTGCCGCCGTAACAGCGGGCTTCACCACCGCGAGCGTGCGCACCGCGCTGGTGGCGCACGAGATCGCCA CGCCCGGCAAGGGGCCGGTGCGGCTGTCGGGCTTCGTGGAGCGGGTGGAGCATCGCCCAAAGGGGGATCGCATCCTGCTG CGTCTCGACGCCGGGCCGGTGAAGGGACTGGACAAGGTTCCGCGCCTCGTCCGCCTCACCCTGCGCAAGGGCTGGGCGCC GCCGGTGGGCACCCATGTCACCCAGCTCGCCCAGTTGCTGCCGCCGCTCGGGCCGGCCATGCCCGGTGCCCATGATTTCG GCCGGAACCCCTGGTTCGCCGGCATCGGCGGCGTGGGCTACGGCCTGGGGCGGCCCAAGCTCGCGGAGCCGGCGGAACCA CCCTTGTCGGTACGCCTCGCCATGGCGGTGGAGGCCGTGCGCGACAGCCTATCCCGCCGCATCCGGGCCTCGCTGTCCGG CACGCCGGCGGAAATCGCCGTCGCGCTGGTAGCAGGCGACCGTTCCGCGATCGCGCCGGAGGTGGAAGAGAGCATGCGCG TGTCCGGGCTCACGCACATCCTGTCCATCTCTGGCCTGCACATGGCGCTGGTCGCGGGCACGCTGTTCGCGTTCATGCGC GGCGGCCTCGCTCTGGTGCCGGCGCTGGCGCTGGGCTTCCCCATCAAGTCGCTGGCGGCCGTCGCCGCCCTCACCGGCAG CGCCGCCTATCTGGTGCTGTCCGGCAATGACGTTCCGGCGCAGCGCTCGTTCGTGATGACAGCGCTGGTATTGAGCGGCG TGCTGGTGGGCCGGCCGGCGCTGACCCTGCGCACCGTGGGCGTGGCCGGGGTCTGCGTGCTCGCCTTCACCCCCGAGGCG GCGCTCGATCCCGGCACGCAAATGTCGTTCGCCGCCACCCTCGCCCTCGTTGCCGCCTATGAGCGCCTGCGGCCCATGCG CGCCCTGCCGCGACCCGACGGATGGGTCGGGCAGGCCGCCATCTGGCTCGCGGTTTTGGTGGGCGGGACGGCGCTCACCT CCCTGGTGGCGGGGCTGGCGACGGCGCCCTACGGCATCTTCCACTTCCAGCGCGTGGCGCCCTATGGCCTGCTCGCCAAT CTCGCCGCCATGCCGGCAGTGTCGTTCATGGTGATGCCCTTCGGCCTGCTGGGCGTGCTGCTGATGCCGTTCGGATTCGA TCATCTGGCCTGGCCGGTGATGGGCAAAGGCATCGAGATCATGGTGGCGGTCTCGGACGCCATCGCGGTGCTGCCAGGGG CCGACGGCAGGGTCGATCCGGTCGGCGCGCCGACGCTCGCCCTGTTCAGCCTGGGCCTGACGGCGCTTTGCCTGCTGCGC GGATGGCTCACGGCGGTCGCGATCGTGCCGTTCGCCCTCGCCCTGCTCATGTCCGGCGCGCCGCCGCGGCCGGACATTCT CATCGCACCCGATGCCCAGACGGTCGCCGTGCGCGGGCCCGACGGGCGGCTCTCGGTGCTCGGCGCGCGCAGCCAGCGGC TGGTGGTGGAGCAGTGGATGACGCGGGAGGGTGACATGCGAAAGGCGGGTGCCGAAGGGCTTGCCGCGCTGTTCACCTGC GATCCCCTCGGCTGCACCGCTCCCTTGCCGGGCGGCGGCACCATCGCCGTATCGCGGCGGGCGGAAAGCCTGGAGGCAGA CTGCCTGGAATCGCGCATTGTCGTCACACGGGATGTGCCGCCCCGGCGCTGTCCGGCCCAGGTGGTGACGCCTGAAACGC TGCAGCGCACCGGCACATTGGCCTATCACTTCCGTAAGGGAATGAGCAGCGAGGGGGCAAGCGGCGGCGACTGGCAGATT GAGCCAACCCGCAAGCCCAACGTCCAGCGCCCCTGGATGCCGCCCCTGCCACCTGAGCCCGCCCCGCAGCGCCCGGCGAC GGACGATCCGGAAGCCGACGCCGCATCGGAGTGA
Upstream 100 bases:
>100_bases CATAGGCGCCGGGCACAAGGAATACGGCCGCCTTGTCCGGCGGGCCGGGCGCCGGACGCCCACGGATCGGAACGACCCGC AGCGGGGCATCTGGGGCGAC
Downstream 100 bases:
>100_bases AGCGGCCAAAAGCATCGACGGCTCAAAAAGCTGGGGTGAGAAGCGTCGCTCCAGAGGAGCCGGTCCCGTTGAGCATGGTG ACCGCCACGCCCCTCACCCC
Product: ComEC/Rec2-like protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 757; Mature: 756
Protein sequence:
>757_residues MTQQDQRPARTSGRAAVLGGARTAARRAMPPGLARVLDALRARLAADLAAEAASGRLILWLPAAFTLGILIYFGAAQEPS LAVAGVLLAALCGGAVLLRARPVAFGAMVALAAVTAGFTTASVRTALVAHEIATPGKGPVRLSGFVERVEHRPKGDRILL RLDAGPVKGLDKVPRLVRLTLRKGWAPPVGTHVTQLAQLLPPLGPAMPGAHDFGRNPWFAGIGGVGYGLGRPKLAEPAEP PLSVRLAMAVEAVRDSLSRRIRASLSGTPAEIAVALVAGDRSAIAPEVEESMRVSGLTHILSISGLHMALVAGTLFAFMR GGLALVPALALGFPIKSLAAVAALTGSAAYLVLSGNDVPAQRSFVMTALVLSGVLVGRPALTLRTVGVAGVCVLAFTPEA ALDPGTQMSFAATLALVAAYERLRPMRALPRPDGWVGQAAIWLAVLVGGTALTSLVAGLATAPYGIFHFQRVAPYGLLAN LAAMPAVSFMVMPFGLLGVLLMPFGFDHLAWPVMGKGIEIMVAVSDAIAVLPGADGRVDPVGAPTLALFSLGLTALCLLR GWLTAVAIVPFALALLMSGAPPRPDILIAPDAQTVAVRGPDGRLSVLGARSQRLVVEQWMTREGDMRKAGAEGLAALFTC DPLGCTAPLPGGGTIAVSRRAESLEADCLESRIVVTRDVPPRRCPAQVVTPETLQRTGTLAYHFRKGMSSEGASGGDWQI EPTRKPNVQRPWMPPLPPEPAPQRPATDDPEADAASE
Sequences:
>Translated_757_residues MTQQDQRPARTSGRAAVLGGARTAARRAMPPGLARVLDALRARLAADLAAEAASGRLILWLPAAFTLGILIYFGAAQEPS LAVAGVLLAALCGGAVLLRARPVAFGAMVALAAVTAGFTTASVRTALVAHEIATPGKGPVRLSGFVERVEHRPKGDRILL RLDAGPVKGLDKVPRLVRLTLRKGWAPPVGTHVTQLAQLLPPLGPAMPGAHDFGRNPWFAGIGGVGYGLGRPKLAEPAEP PLSVRLAMAVEAVRDSLSRRIRASLSGTPAEIAVALVAGDRSAIAPEVEESMRVSGLTHILSISGLHMALVAGTLFAFMR GGLALVPALALGFPIKSLAAVAALTGSAAYLVLSGNDVPAQRSFVMTALVLSGVLVGRPALTLRTVGVAGVCVLAFTPEA ALDPGTQMSFAATLALVAAYERLRPMRALPRPDGWVGQAAIWLAVLVGGTALTSLVAGLATAPYGIFHFQRVAPYGLLAN LAAMPAVSFMVMPFGLLGVLLMPFGFDHLAWPVMGKGIEIMVAVSDAIAVLPGADGRVDPVGAPTLALFSLGLTALCLLR GWLTAVAIVPFALALLMSGAPPRPDILIAPDAQTVAVRGPDGRLSVLGARSQRLVVEQWMTREGDMRKAGAEGLAALFTC DPLGCTAPLPGGGTIAVSRRAESLEADCLESRIVVTRDVPPRRCPAQVVTPETLQRTGTLAYHFRKGMSSEGASGGDWQI EPTRKPNVQRPWMPPLPPEPAPQRPATDDPEADAASE >Mature_756_residues TQQDQRPARTSGRAAVLGGARTAARRAMPPGLARVLDALRARLAADLAAEAASGRLILWLPAAFTLGILIYFGAAQEPSL AVAGVLLAALCGGAVLLRARPVAFGAMVALAAVTAGFTTASVRTALVAHEIATPGKGPVRLSGFVERVEHRPKGDRILLR LDAGPVKGLDKVPRLVRLTLRKGWAPPVGTHVTQLAQLLPPLGPAMPGAHDFGRNPWFAGIGGVGYGLGRPKLAEPAEPP LSVRLAMAVEAVRDSLSRRIRASLSGTPAEIAVALVAGDRSAIAPEVEESMRVSGLTHILSISGLHMALVAGTLFAFMRG GLALVPALALGFPIKSLAAVAALTGSAAYLVLSGNDVPAQRSFVMTALVLSGVLVGRPALTLRTVGVAGVCVLAFTPEAA LDPGTQMSFAATLALVAAYERLRPMRALPRPDGWVGQAAIWLAVLVGGTALTSLVAGLATAPYGIFHFQRVAPYGLLANL AAMPAVSFMVMPFGLLGVLLMPFGFDHLAWPVMGKGIEIMVAVSDAIAVLPGADGRVDPVGAPTLALFSLGLTALCLLRG WLTAVAIVPFALALLMSGAPPRPDILIAPDAQTVAVRGPDGRLSVLGARSQRLVVEQWMTREGDMRKAGAEGLAALFTCD PLGCTAPLPGGGTIAVSRRAESLEADCLESRIVVTRDVPPRRCPAQVVTPETLQRTGTLAYHFRKGMSSEGASGGDWQIE PTRKPNVQRPWMPPLPPEPAPQRPATDDPEADAASE
Specific function: The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding [H]
COG id: COG0658
COG function: function code R; Predicted membrane metal-binding protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: To H.influenzae REC2, N.gonorrhoeae ComA and E.coli YcaI [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001279 - InterPro: IPR004477 - InterPro: IPR004797 [H]
Pfam domain/function: PF03772 Competence; PF00753 Lactamase_B [H]
EC number: NA
Molecular weight: Translated: 78600; Mature: 78469
Theoretical pI: Translated: 10.38; Mature: 10.38
Prosite motif: PS00284 SERPIN
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.9 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTQQDQRPARTSGRAAVLGGARTAARRAMPPGLARVLDALRARLAADLAAEAASGRLILW CCCCCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE LPAAFTLGILIYFGAAQEPSLAVAGVLLAALCGGAVLLRARPVAFGAMVALAAVTAGFTT EHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCHH ASVRTALVAHEIATPGKGPVRLSGFVERVEHRPKGDRILLRLDAGPVKGLDKVPRLVRLT HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH LRKGWAPPVGTHVTQLAQLLPPLGPAMPGAHDFGRNPWFAGIGGVGYGLGRPKLAEPAEP HHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCC PLSVRLAMAVEAVRDSLSRRIRASLSGTPAEIAVALVAGDRSAIAPEVEESMRVSGLTHI CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCCCCCCHHHHHHHHHHHHHH LSISGLHMALVAGTLFAFMRGGLALVPALALGFPIKSLAAVAALTGSAAYLVLSGNDVPA HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCC QRSFVMTALVLSGVLVGRPALTLRTVGVAGVCVLAFTPEAALDPGTQMSFAATLALVAAY HHHHHHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCHHHCCCCCCHHHHHHHHHHHHH ERLRPMRALPRPDGWVGQAAIWLAVLVGGTALTSLVAGLATAPYGIFHFQRVAPYGLLAN HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH LAAMPAVSFMVMPFGLLGVLLMPFGFDHLAWPVMGKGIEIMVAVSDAIAVLPGADGRVDP HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCC VGAPTLALFSLGLTALCLLRGWLTAVAIVPFALALLMSGAPPRPDILIAPDAQTVAVRGP CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECC DGRLSVLGARSQRLVVEQWMTREGDMRKAGAEGLAALFTCDPLGCTAPLPGGGTIAVSRR CCCEEEECCCCHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEECC AESLEADCLESRIVVTRDVPPRRCPAQVVTPETLQRTGTLAYHFRKGMSSEGASGGDWQI HHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEE EPTRKPNVQRPWMPPLPPEPAPQRPATDDPEADAASE CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure TQQDQRPARTSGRAAVLGGARTAARRAMPPGLARVLDALRARLAADLAAEAASGRLILW CCCCCCCCCCCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE LPAAFTLGILIYFGAAQEPSLAVAGVLLAALCGGAVLLRARPVAFGAMVALAAVTAGFTT EHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCHH ASVRTALVAHEIATPGKGPVRLSGFVERVEHRPKGDRILLRLDAGPVKGLDKVPRLVRLT HHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHH LRKGWAPPVGTHVTQLAQLLPPLGPAMPGAHDFGRNPWFAGIGGVGYGLGRPKLAEPAEP HHCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHCCCCCCEECCCCCCCCCCCCCCCCCCCC PLSVRLAMAVEAVRDSLSRRIRASLSGTPAEIAVALVAGDRSAIAPEVEESMRVSGLTHI CHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCCCCCCCHHHHHHHHHHHHHH LSISGLHMALVAGTLFAFMRGGLALVPALALGFPIKSLAAVAALTGSAAYLVLSGNDVPA HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCC QRSFVMTALVLSGVLVGRPALTLRTVGVAGVCVLAFTPEAALDPGTQMSFAATLALVAAY HHHHHHHHHHHHHHHHCCCCCEEEECCHHEEEEEEECCHHHCCCCCCHHHHHHHHHHHHH ERLRPMRALPRPDGWVGQAAIWLAVLVGGTALTSLVAGLATAPYGIFHFQRVAPYGLLAN HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH LAAMPAVSFMVMPFGLLGVLLMPFGFDHLAWPVMGKGIEIMVAVSDAIAVLPGADGRVDP HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCC VGAPTLALFSLGLTALCLLRGWLTAVAIVPFALALLMSGAPPRPDILIAPDAQTVAVRGP CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCEEEEECC DGRLSVLGARSQRLVVEQWMTREGDMRKAGAEGLAALFTCDPLGCTAPLPGGGTIAVSRR CCCEEEECCCCHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEEECC AESLEADCLESRIVVTRDVPPRRCPAQVVTPETLQRTGTLAYHFRKGMSSEGASGGDWQI HHHHHHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHCCCHHHHHHHCCCCCCCCCCCEEE EPTRKPNVQRPWMPPLPPEPAPQRPATDDPEADAASE CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7968523; 8969508; 9384377 [H]