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The map label for this gene is lldR [H]

Identifier: 154247853

GI number: 154247853

Start: 4348346

End: 4349104

Strand: Reverse

Name: lldR [H]

Synonym: Xaut_3930

Alternate gene names: 154247853

Gene position: 4349104-4348346 (Counterclockwise)

Preceding gene: 154247855

Following gene: 154247852

Centisome position: 81.92

GC content: 69.57

Gene sequence:

>759_bases
GTGCGAAAGCTGTCGGACGAGATCGAGGCGTTGATCGCCGAAGGCGGGCTTCAGACCGGCGCGCGGCTGCCGTCCGAACG
CAAGCTGGCGGCGGATTTCGGCGTGTCACGCTCGCGGCTGCGCGAAGCCATCCAGCAGCTCACCAGCCGGGGCATCCTCA
CCGCGCGCCAGGGCGGCGGCACCTTCGTGGCCGCCACGCTCTCTCCATCGTCCCTGGACAAGGCCCTCTCCCCGCTCTCC
TCGCTCGCCCGCATGGAGCCAGGCTACTGGCAGGATGTGATGGAGATCCGCAAGTCGCTGGATGGCGACACCGCCTATTG
CGCGGCCTTGCGCGCAGGCGATGAGGACCGGGCGCGGCTCACAGCCGCCTTCGAGCGGCTCCTCAAGGCCGAGGGCGCGG
ACGAGGCGACCCAGGCCGGCGCCGACGCCGCCTTCCACATGGCGGTGGCCGAGGCCTCCCACAATGCGGTGCTGCGCCAA
GTGATGGCGGGACTGTTCGACGTGCTGCAGCACTCCATTTCCGCCAGCCTCGAAAAGCTCTACCGCCTACCGCGCACGGC
GCACGCGCTGGAAGACCAGCATCGCCTGATCTTCGAGGCCGTCGTGGAAGGCCGCGCCGACGACGCGCGCGACGCCGCGC
TGCGCCATCTCGATTTCGTGGAGGACAGCCTGCGGCTCATAGAAGACGCCGCAGCGCGCGAGCGACGCTCGGTGCGGGCC
CTTTCCCGGGCGGCGATGCAGAAGGAAGCAAGATCATGA

Upstream 100 bases:

>100_bases
CATCGCGCTTGGATTGCCAAAATTGGTCAGACCAATTATACTGGTAACCGCGCGACAAGGTGGCACCACAGGTGCCGAAT
TTCCCGGCTGGGAGGGGCGG

Downstream 100 bases:

>100_bases
TCATCTCGTCGTCCTCCGACTACCGGGAAGCCGCCCGCCGCCGCCTTCCGCCCTTCCTGTTCCACTATATCGACGGCGGC
GCCTATGCCGAGGCGACCCT

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MRKLSDEIEALIAEGGLQTGARLPSERKLAADFGVSRSRLREAIQQLTSRGILTARQGGGTFVAATLSPSSLDKALSPLS
SLARMEPGYWQDVMEIRKSLDGDTAYCAALRAGDEDRARLTAAFERLLKAEGADEATQAGADAAFHMAVAEASHNAVLRQ
VMAGLFDVLQHSISASLEKLYRLPRTAHALEDQHRLIFEAVVEGRADDARDAALRHLDFVEDSLRLIEDAAARERRSVRA
LSRAAMQKEARS

Sequences:

>Translated_252_residues
MRKLSDEIEALIAEGGLQTGARLPSERKLAADFGVSRSRLREAIQQLTSRGILTARQGGGTFVAATLSPSSLDKALSPLS
SLARMEPGYWQDVMEIRKSLDGDTAYCAALRAGDEDRARLTAAFERLLKAEGADEATQAGADAAFHMAVAEASHNAVLRQ
VMAGLFDVLQHSISASLEKLYRLPRTAHALEDQHRLIFEAVVEGRADDARDAALRHLDFVEDSLRLIEDAAARERRSVRA
LSRAAMQKEARS
>Mature_252_residues
MRKLSDEIEALIAEGGLQTGARLPSERKLAADFGVSRSRLREAIQQLTSRGILTARQGGGTFVAATLSPSSLDKALSPLS
SLARMEPGYWQDVMEIRKSLDGDTAYCAALRAGDEDRARLTAAFERLLKAEGADEATQAGADAAFHMAVAEASHNAVLRQ
VMAGLFDVLQHSISASLEKLYRLPRTAHALEDQHRLIFEAVVEGRADDARDAALRHLDFVEDSLRLIEDAAARERRSVRA
LSRAAMQKEARS

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=242, Percent_Identity=41.7355371900826, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1786303, Length=230, Percent_Identity=41.7391304347826, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789353, Length=231, Percent_Identity=35.0649350649351, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1790780, Length=230, Percent_Identity=29.5652173913043, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI48994955, Length=208, Percent_Identity=26.4423076923077, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 27452; Mature: 27452

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLSDEIEALIAEGGLQTGARLPSERKLAADFGVSRSRLREAIQQLTSRGILTARQGGG
CCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCC
TFVAATLSPSSLDKALSPLSSLARMEPGYWQDVMEIRKSLDGDTAYCAALRAGDEDRARL
EEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
TAAFERLLKAEGADEATQAGADAAFHMAVAEASHNAVLRQVMAGLFDVLQHSISASLEKL
HHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLPRTAHALEDQHRLIFEAVVEGRADDARDAALRHLDFVEDSLRLIEDAAARERRSVRA
HHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRAAMQKEARS
HHHHHHHHHHCC
>Mature Secondary Structure
MRKLSDEIEALIAEGGLQTGARLPSERKLAADFGVSRSRLREAIQQLTSRGILTARQGGG
CCCHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEECCCC
TFVAATLSPSSLDKALSPLSSLARMEPGYWQDVMEIRKSLDGDTAYCAALRAGDEDRARL
EEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHH
TAAFERLLKAEGADEATQAGADAAFHMAVAEASHNAVLRQVMAGLFDVLQHSISASLEKL
HHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLPRTAHALEDQHRLIFEAVVEGRADDARDAALRHLDFVEDSLRLIEDAAARERRSVRA
HHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSRAAMQKEARS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]