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The map label for this gene is ygfU [H]

Identifier: 154247220

GI number: 154247220

Start: 3654833

End: 3656224

Strand: Direct

Name: ygfU [H]

Synonym: Xaut_3292

Alternate gene names: 154247220

Gene position: 3654833-3656224 (Clockwise)

Preceding gene: 154247209

Following gene: 154247222

Centisome position: 68.84

GC content: 64.8

Gene sequence:

>1392_bases
ATGTCCGAAGCCGTTCATCCCGTAGACGAAATATTGCCAGCTCCGAAACTCGCGATTCTCGGCCTCCAGCATGTGCTGGT
GATGTATGCCGGTGCAGTGGCGGTGCCGCTCATCATCGGCCGCGCGCTGAAGCTGCCGCCCCAGGATGTAGCCTTCCTCA
TCAGCGCGGACCTGTTTGCCTGCGGTCTCGCGACGCTGGCCCAGTGCCTTGGCTTCCTCGGCGTCGGCATCCGCCTGCCG
GTGATGATGGGCGTCACCTTCGCCTCGGTCGGCCCCATGCTCTCGATGGCTGCGAGCCCGGAGATCGGCCTGTTGGGCAT
CTACGGCTCGGTGATCGCGGCGGGCATCTTCGGCATCATCGTCGCGCCTTTCGTCTCGCGGCTGTTGCCCCTGTTCCCGC
CGGTGGTGACCGGCACCATCATCCTCATCATCGGCATCTCGCTCATGCGGGTGGGCATCAACTGGGCCGGCGGTGGCATC
CCGTTCCTGACCCAGACCATCGACGGCAAGGTGGTGCAGGTGGCCAATCCCAATTACGGCCAGCTTCAGGGTCTCGGCAT
TTCCCTGTTCGTGATGCTGGTCGTCCTCGGCCTCATCAAGTGGGGCAAGGGTTTCCTTGCCAACGTGGCGGTGCTGCTCG
GCATCATCGCCGGCGCGGTGCTGGCGACCTTCCTCGGCATCATGCATTTCGAGAAGGTGGCCGCGGCGTCCTGGTTCGAC
GTGATCCTGCCGTTCCACTTTGGCATGCCCACGTTCCACATCGTCCCCATCATCACCATGTGCATCGTGATGGTCGTGGT
GATGATCGAATCGGTGGGCATGTTCCTCGCCCTCTCGGACATCACCGGCAAGCCCGTGGACCAGAAGGCGCTCACCAAGG
GCCTGCGCGCCGACGGCGTGGGCACCCTTCTCGGCGGCGTTTTCAACACCTTCCCCTACACCTCCTTCTCGCAGAACGTG
GGCCTTGTCGGCGTCACCGGCGTGCGCTCGCGCTGGGTGACGGTGGTGGGCGGCCTGATCATGCTCGGCCTCGGCCTGCT
GCCGAAGATGGCGGCGCTGGTGGAGGCGGTGCCCCAGGTGGTGCTGGGTGGCGCGGGCCTCGTCATGTTCGGCATGGTGG
CGGCCACCGGTGCGCGCATCCTCACCGGCGTCGACTTCAAGACCAACCGCTTCAACCTGTTCATCGTCGCGGTGTCGGTG
GGCTTCGGCATGATCCCGCTGGTCTCGCCCAACTTCTTCAAGAACCTGCCGCACGAGCTGCATCCGCTGCTGGAGAGCGG
GATCCTGCTCTGCGCCATTGTCGCCGTGCTGCTCAACGTCTTCTTCAATGGCGTGAAGAAGACCTCCACCGAGGAGATCG
TCGCGGCGGCCAAGCAGGCCGAGGCCCACTGA

Upstream 100 bases:

>100_bases
AGACCCGCCGGACCGGTACCCGCGCCGCACGCAAAGATGGCGCCAATAAACGAAAAACGCCCTTCCGCACCTGACCCGAC
TTCCTTTCCAGGGGGACCTC

Downstream 100 bases:

>100_bases
CGTGGGCCGGGGGCGGGGAAAGGGGAGCGGTGCAAGGATGAACGCGGCCAATCAGGGCTTGGCTTTGCGCTCAGGCGGAC
AGCCGCTCCCCGATCTTCCC

Product: uracil-xanthine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSEAVHPVDEILPAPKLAILGLQHVLVMYAGAVAVPLIIGRALKLPPQDVAFLISADLFACGLATLAQCLGFLGVGIRLP
VMMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGIFGIIVAPFVSRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGI
PFLTQTIDGKVVQVANPNYGQLQGLGISLFVMLVVLGLIKWGKGFLANVAVLLGIIAGAVLATFLGIMHFEKVAAASWFD
VILPFHFGMPTFHIVPIITMCIVMVVVMIESVGMFLALSDITGKPVDQKALTKGLRADGVGTLLGGVFNTFPYTSFSQNV
GLVGVTGVRSRWVTVVGGLIMLGLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILTGVDFKTNRFNLFIVAVSV
GFGMIPLVSPNFFKNLPHELHPLLESGILLCAIVAVLLNVFFNGVKKTSTEEIVAAAKQAEAH

Sequences:

>Translated_463_residues
MSEAVHPVDEILPAPKLAILGLQHVLVMYAGAVAVPLIIGRALKLPPQDVAFLISADLFACGLATLAQCLGFLGVGIRLP
VMMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGIFGIIVAPFVSRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGI
PFLTQTIDGKVVQVANPNYGQLQGLGISLFVMLVVLGLIKWGKGFLANVAVLLGIIAGAVLATFLGIMHFEKVAAASWFD
VILPFHFGMPTFHIVPIITMCIVMVVVMIESVGMFLALSDITGKPVDQKALTKGLRADGVGTLLGGVFNTFPYTSFSQNV
GLVGVTGVRSRWVTVVGGLIMLGLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILTGVDFKTNRFNLFIVAVSV
GFGMIPLVSPNFFKNLPHELHPLLESGILLCAIVAVLLNVFFNGVKKTSTEEIVAAAKQAEAH
>Mature_462_residues
SEAVHPVDEILPAPKLAILGLQHVLVMYAGAVAVPLIIGRALKLPPQDVAFLISADLFACGLATLAQCLGFLGVGIRLPV
MMGVTFASVGPMLSMAASPEIGLLGIYGSVIAAGIFGIIVAPFVSRLLPLFPPVVTGTIILIIGISLMRVGINWAGGGIP
FLTQTIDGKVVQVANPNYGQLQGLGISLFVMLVVLGLIKWGKGFLANVAVLLGIIAGAVLATFLGIMHFEKVAAASWFDV
ILPFHFGMPTFHIVPIITMCIVMVVVMIESVGMFLALSDITGKPVDQKALTKGLRADGVGTLLGGVFNTFPYTSFSQNVG
LVGVTGVRSRWVTVVGGLIMLGLGLLPKMAALVEAVPQVVLGGAGLVMFGMVAATGARILTGVDFKTNRFNLFIVAVSVG
FGMIPLVSPNFFKNLPHELHPLLESGILLCAIVAVLLNVFFNGVKKTSTEEIVAAAKQAEAH

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=459, Percent_Identity=25.9259259259259, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI44680148, Length=235, Percent_Identity=32.3404255319149, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI40316845, Length=235, Percent_Identity=32.3404255319149, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI44680143, Length=187, Percent_Identity=33.6898395721925, Blast_Score=93, Evalue=5e-19,
Organism=Escherichia coli, GI87082181, Length=447, Percent_Identity=53.2438478747204, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI1790087, Length=458, Percent_Identity=29.0393013100437, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI87082178, Length=476, Percent_Identity=26.6806722689076, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI87081818, Length=415, Percent_Identity=28.9156626506024, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788843, Length=473, Percent_Identity=27.6955602536998, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=474, Percent_Identity=24.6835443037975, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17542260, Length=223, Percent_Identity=25.1121076233184, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=221, Percent_Identity=24.8868778280543, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=175, Percent_Identity=33.1428571428571, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48337; Mature: 48206

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEAVHPVDEILPAPKLAILGLQHVLVMYAGAVAVPLIIGRALKLPPQDVAFLISADLFA
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH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HHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]