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The map label for this gene is cobK [H]

Identifier: 154247209

GI number: 154247209

Start: 3641870

End: 3642733

Strand: Direct

Name: cobK [H]

Synonym: Xaut_3281

Alternate gene names: 154247209

Gene position: 3641870-3642733 (Clockwise)

Preceding gene: 154247205

Following gene: 154247220

Centisome position: 68.6

GC content: 73.84

Gene sequence:

>864_bases
ATGGTTCCGCGCATTCTCCTGCTGGGCGGCACCAGCGAGGCCAGTGCCCTCGCGAGGCGGCTTGCCGCCCGCATCGCCGA
TCATGCCGGCCTCCACGTGGTCCTGTCGCTGGCGGGGCGCACGGAACATCCCGCGCCCCAGCCGGTGCCCGTGCGCGTCG
GCGGCTTCGGCGGCGCTGAGGGCCTTGAAGACTACCTGAAGGCGGAGCGCATTGTCGCCGTGGTGGACGCCACCCATCCC
TATGCCGCCCGCATGTCCTTCAATGCGGCTGATGCCTGCGCGGCGGCGGGCGTGCCCCTCCTCGCCCTGCGGCGCGGGCC
ATGGATGCCCGTTGCCGGCGATCGCTGGCGGGAGGTGGCCGATGTGCCGGCGGCGGTCGCCGCGCTGGGGGATGCGCCGC
GGCGGGTGTTCCTCGCCCTCGGGCGCAACGAGGTGCGCGCCTTCGAGGCGGCGCCGCAGCATGTCTATCTGGTGCGCAGT
GTCGATCCGGTCACCCCGCCGCTGGCGGTGCCTGAGGCCGAATACGTGCTGGGGCGTGGCCCGTTCGGCGAGGCCGAAGA
CCGCGCGCTGCTGGAGGCGCACCGCATCGACACCATCGTGGCCAAGAACAGCGGCGGCTCGGCCACCTACGGCAAGATGG
CGGCCGCCCGCGCGCTGGGCATCGAGGTGCTGCTGATCGCGCGGCCCGCCATTCCCGCCGTCCCGGCGGTGGAGACGCCG
GCGGAAGCCGAGGCATGGCTGCTCGACCGGCTCGGCGCTCACGGCGCGGATTCCTCCACTGGAGACACGGGCTCTTCTCC
CGCTCGCGGCGCGGACTCTCCTTCCGCTCGTGGCGCGGGCCTGTCCGCCGAGCGGGGTGCGTAG

Upstream 100 bases:

>100_bases
CCCATCCTCGCCGATGCCGACGATGGACAGCCAGCGCCCCGCTGGGGCACTTATGCCCGCCATGAGCGATCCCTCCGTCT
CGACCCGCGCCGTTTCAGCC

Downstream 100 bases:

>100_bases
ACCAAAGGCGGCAGGCCGGGACGCGGCACGATGCGGGTGTCGGTGGTGCCGATAATCACGCAGGTGGCCATGTCAGCCTG
CGCCGGGTCGGCCTCGGCCA

Product: precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MVPRILLLGGTSEASALARRLAARIADHAGLHVVLSLAGRTEHPAPQPVPVRVGGFGGAEGLEDYLKAERIVAVVDATHP
YAARMSFNAADACAAAGVPLLALRRGPWMPVAGDRWREVADVPAAVAALGDAPRRVFLALGRNEVRAFEAAPQHVYLVRS
VDPVTPPLAVPEAEYVLGRGPFGEAEDRALLEAHRIDTIVAKNSGGSATYGKMAAARALGIEVLLIARPAIPAVPAVETP
AEAEAWLLDRLGAHGADSSTGDTGSSPARGADSPSARGAGLSAERGA

Sequences:

>Translated_287_residues
MVPRILLLGGTSEASALARRLAARIADHAGLHVVLSLAGRTEHPAPQPVPVRVGGFGGAEGLEDYLKAERIVAVVDATHP
YAARMSFNAADACAAAGVPLLALRRGPWMPVAGDRWREVADVPAAVAALGDAPRRVFLALGRNEVRAFEAAPQHVYLVRS
VDPVTPPLAVPEAEYVLGRGPFGEAEDRALLEAHRIDTIVAKNSGGSATYGKMAAARALGIEVLLIARPAIPAVPAVETP
AEAEAWLLDRLGAHGADSSTGDTGSSPARGADSPSARGAGLSAERGA
>Mature_287_residues
MVPRILLLGGTSEASALARRLAARIADHAGLHVVLSLAGRTEHPAPQPVPVRVGGFGGAEGLEDYLKAERIVAVVDATHP
YAARMSFNAADACAAAGVPLLALRRGPWMPVAGDRWREVADVPAAVAALGDAPRRVFLALGRNEVRAFEAAPQHVYLVRS
VDPVTPPLAVPEAEYVLGRGPFGEAEDRALLEAHRIDTIVAKNSGGSATYGKMAAARALGIEVLLIARPAIPAVPAVETP
AEAEAWLLDRLGAHGADSSTGDTGSSPARGADSPSARGAGLSAERGA

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 29558; Mature: 29558

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPRILLLGGTSEASALARRLAARIADHAGLHVVLSLAGRTEHPAPQPVPVRVGGFGGAE
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHH
GLEDYLKAERIVAVVDATHPYAARMSFNAADACAAAGVPLLALRRGPWMPVAGDRWREVA
HHHHHHHHHHEEEEEECCCCEEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
DVPAAVAALGDAPRRVFLALGRNEVRAFEAAPQHVYLVRSVDPVTPPLAVPEAEYVLGRG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCC
PFGEAEDRALLEAHRIDTIVAKNSGGSATYGKMAAARALGIEVLLIARPAIPAVPAVETP
CCCCCHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCC
AEAEAWLLDRLGAHGADSSTGDTGSSPARGADSPSARGAGLSAERGA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVPRILLLGGTSEASALARRLAARIADHAGLHVVLSLAGRTEHPAPQPVPVRVGGFGGAE
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHH
GLEDYLKAERIVAVVDATHPYAARMSFNAADACAAAGVPLLALRRGPWMPVAGDRWREVA
HHHHHHHHHHEEEEEECCCCEEEEEECCHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHH
DVPAAVAALGDAPRRVFLALGRNEVRAFEAAPQHVYLVRSVDPVTPPLAVPEAEYVLGRG
HHHHHHHHHCCCCCEEEEEECCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCEEECCC
PFGEAEDRALLEAHRIDTIVAKNSGGSATYGKMAAARALGIEVLLIARPAIPAVPAVETP
CCCCCHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCC
AEAEAWLLDRLGAHGADSSTGDTGSSPARGADSPSARGAGLSAERGA
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]