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The map label for this gene is gap [H]

Identifier: 154247004

GI number: 154247004

Start: 3414132

End: 3415142

Strand: Direct

Name: gap [H]

Synonym: Xaut_3075

Alternate gene names: 154247004

Gene position: 3414132-3415142 (Clockwise)

Preceding gene: 154247003

Following gene: 154247005

Centisome position: 64.31

GC content: 66.77

Gene sequence:

>1011_bases
ATGAGCGTCAAGGTGGCCATCAACGGTTTCGGTCGCATCGGGCGTAACGTTCTGCGCGCCATCATCGAATCGGGTCGGAC
CGACATCGAGGTGGTGGCGATCAACGATCTCGGCCCGGTGGAGACGAACGCCCACCTGTTCCGCTTCGACAGCGTGCACG
GCCGCTTCTCCGGCGAGGTCAAGGTTGCCGGCGATACCATCGACGTGGGCCGCGGCCCCATCAAGGTCACCGCGGTGCGC
GATCCCGCCCAACTGCCCCACAAGGATCTGGGCGTGGACATCGCGCTCGAGTGCACCGGCATCTTCACCGCCCGCGACAA
GGCGGCCGCGCACCTCGCGGCCGGTGCCCGGCGCGTGCTGGTCTCGGCCCCGGCCGAGGGCGCCGACCTGACGGTGGTCT
ACGGTGTGAACCACGACAAGCTCACCTCCGAGCACCTCGTGGTCTCCAACGCCTCCTGCACCACCAACTGTCTCGCCCCC
GTCGCGAAGGTCCTGAATGATGCCGTCGGCATCGAGAAGGGCTTCATGACCACGATCCACTCCTACACCGGCGACCAGCC
GACGCTGGACACCATGCACAAGGACCTCTACCGCGCCCGCGCGGCGGCCATGTCCATGATCCCCACGTCCACCGGCGCCG
CCAAGGCGGTGGGCCTGGTCCTGCCCGAGCTGAACGGCAAGCTGGACGGCACCTCCATCCGCGTGCCGACCCCGAACGTC
TCGGTGGTGGACTTCAAGTTCATCGCCAAGCGCGCCACCACCAAGGACGAGATCAACGCCGCCGTCCTCGCCGCGGCTGC
GTCCGGTCCGCTGAAGGGCATTCTCGGCACCACCGACCAGCCCAACGTCTCCATCGACTTCAACCACGATCCGCACTCCT
CCACCCTGCACCTCGACCAGACCAAGGTCCTGGAAGGCACTCTGGTGCGCGTGCTGTCCTGGTATGACAACGAGTGGGGC
TTCTCCAACCGCATGGCCGACACTGCAGTCGCCATGGGCAAGCTCGGTTGA

Upstream 100 bases:

>100_bases
GCACGGCGGGCGCGACCAGGCCGCACCGCGGGCTCTTCCGCGGGTGCGCAACGCAGTTTCGCAGAGGCCGGGCTTCAAGC
CGGCTCAAGGAGGACCCATT

Downstream 100 bases:

>100_bases
GCGGGGAAGGGGGCGCCAAGATGACCGCCTTCCGAACCCTCGACGACGCGGACCTTGCCGACAAGCGGGTCCTCGTGCGC
GTTGACCTCAACGTGCCCAT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFSGEVKVAGDTIDVGRGPIKVTAVR
DPAQLPHKDLGVDIALECTGIFTARDKAAAHLAAGARRVLVSAPAEGADLTVVYGVNHDKLTSEHLVVSNASCTTNCLAP
VAKVLNDAVGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELNGKLDGTSIRVPTPNV
SVVDFKFIAKRATTKDEINAAVLAAAASGPLKGILGTTDQPNVSIDFNHDPHSSTLHLDQTKVLEGTLVRVLSWYDNEWG
FSNRMADTAVAMGKLG

Sequences:

>Translated_336_residues
MSVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFSGEVKVAGDTIDVGRGPIKVTAVR
DPAQLPHKDLGVDIALECTGIFTARDKAAAHLAAGARRVLVSAPAEGADLTVVYGVNHDKLTSEHLVVSNASCTTNCLAP
VAKVLNDAVGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELNGKLDGTSIRVPTPNV
SVVDFKFIAKRATTKDEINAAVLAAAASGPLKGILGTTDQPNVSIDFNHDPHSSTLHLDQTKVLEGTLVRVLSWYDNEWG
FSNRMADTAVAMGKLG
>Mature_335_residues
SVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFSGEVKVAGDTIDVGRGPIKVTAVRD
PAQLPHKDLGVDIALECTGIFTARDKAAAHLAAGARRVLVSAPAEGADLTVVYGVNHDKLTSEHLVVSNASCTTNCLAPV
AKVLNDAVGIEKGFMTTIHSYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELNGKLDGTSIRVPTPNVS
VVDFKFIAKRATTKDEINAAVLAAAASGPLKGILGTTDQPNVSIDFNHDPHSSTLHLDQTKVLEGTLVRVLSWYDNEWGF
SNRMADTAVAMGKLG

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=48.4939759036145, Blast_Score=300, Evalue=1e-81,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=45.2599388379205, Blast_Score=266, Evalue=2e-71,
Organism=Escherichia coli, GI1789295, Length=338, Percent_Identity=49.112426035503, Blast_Score=334, Evalue=4e-93,
Organism=Escherichia coli, GI1788079, Length=328, Percent_Identity=49.6951219512195, Blast_Score=304, Evalue=7e-84,
Organism=Caenorhabditis elegans, GI17534677, Length=331, Percent_Identity=49.2447129909366, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17534679, Length=331, Percent_Identity=48.9425981873112, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI32566163, Length=332, Percent_Identity=48.7951807228916, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17568413, Length=332, Percent_Identity=48.7951807228916, Blast_Score=286, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321631, Length=329, Percent_Identity=51.6717325227964, Blast_Score=302, Evalue=4e-83,
Organism=Saccharomyces cerevisiae, GI6322468, Length=329, Percent_Identity=50.7598784194529, Blast_Score=300, Evalue=2e-82,
Organism=Saccharomyces cerevisiae, GI6322409, Length=329, Percent_Identity=49.8480243161094, Blast_Score=300, Evalue=3e-82,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=50.6134969325153, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=50.6134969325153, Blast_Score=296, Evalue=2e-80,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=50.920245398773, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=50.920245398773, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=42.0245398773006, Blast_Score=246, Evalue=2e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35538; Mature: 35407

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFSGEV
CEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEE
KVAGDTIDVGRGPIKVTAVRDPAQLPHKDLGVDIALECTGIFTARDKAAAHLAAGARRVL
EEECCEEECCCCCEEEEEECCHHHCCHHHCCEEEEEEEEEEEEECCHHHHHHHHCCEEEE
VSAPAEGADLTVVYGVNHDKLTSEHLVVSNASCTTNCLAPVAKVLNDAVGIEKGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELNGKLDGTSIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCCCCCCEEEECCCCC
SVVDFKFIAKRATTKDEINAAVLAAAASGPLKGILGTTDQPNVSIDFNHDPHSSTLHLDQ
EEEEHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECH
TKVLEGTLVRVLSWYDNEWGFSNRMADTAVAMGKLG
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SVKVAINGFGRIGRNVLRAIIESGRTDIEVVAINDLGPVETNAHLFRFDSVHGRFSGEV
EEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCEE
KVAGDTIDVGRGPIKVTAVRDPAQLPHKDLGVDIALECTGIFTARDKAAAHLAAGARRVL
EEECCEEECCCCCEEEEEECCHHHCCHHHCCEEEEEEEEEEEEECCHHHHHHHHCCEEEE
VSAPAEGADLTVVYGVNHDKLTSEHLVVSNASCTTNCLAPVAKVLNDAVGIEKGFMTTIH
EECCCCCCCEEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
SYTGDQPTLDTMHKDLYRARAAAMSMIPTSTGAAKAVGLVLPELNGKLDGTSIRVPTPNV
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEEECCCCCCCCCEEEECCCCC
SVVDFKFIAKRATTKDEINAAVLAAAASGPLKGILGTTDQPNVSIDFNHDPHSSTLHLDQ
EEEEHHHHHHHCCCHHHCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECH
TKVLEGTLVRVLSWYDNEWGFSNRMADTAVAMGKLG
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]