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The map label for this gene is cbbT [H]

Identifier: 154247003

GI number: 154247003

Start: 3412032

End: 3414023

Strand: Direct

Name: cbbT [H]

Synonym: Xaut_3074

Alternate gene names: 154247003

Gene position: 3412032-3414023 (Clockwise)

Preceding gene: 154247001

Following gene: 154247004

Centisome position: 64.27

GC content: 69.13

Gene sequence:

>1992_bases
ATGCTGAGCCGCACGAGTCACGACCGCATGGCCAACGCCATCCGCTTCCTTGCCATGGACGCCGTGGAAGCTGCCAATAG
CGGTCATCCCGGCCTGCCGATGGGTGCTGCGGACATCGCCACCGTCCTGTTCACCAAGGTCCTGAAGTACGATCCCACGC
GCCCCTTCTGGCCCGATCGCGACCGCTTCGTGCTGTCCGCCGGCCACGGCTCCATGCTGCTCTATTCGGTGCTGCATCTG
GCCGGCTACGAGAAGGTGACGATCGAGGAGATCAAGCGCTTCCGCAAGCTCGGCTCGCTTACCCCCGGCCATCCCGAGAA
CTTCGTCACCGAAGGCATCGAGACCACCACCGGCCCGCTCGGGCAGGGCATCGCCACCGCCGTGGGCATGGCCATGGCCG
AGCGCGCGCTCGCCGCCCGCTTCGGCAAGGACGTGGTGGACCACCACACCTTCGTGCTCTGCTCCGACGGCGACCTGATG
GAGGGCATCAGCCAGGAGGCGGCGGACCTTGCCGGCCACCTGAAGCTCTCCAAGCTCATCGTCATGTGGGATGACAACGG
CATCTCCATCGACGGCGCCACCTCCATCTCCGGTTCCACCGACCAGCTGGCGCGCTTCGCCGCCTCGGGGTGGGCGACCA
CGCGCATCGATGGCCACGATCCGGACGCCATCCTTGCCGCGCTGACCGCCGCCAAGGCCTCGGACCGGCCGACCCTGATC
GCCTGCCGCACCGTCATCGGCTTCGGCAGTCCCAAGAAGGCCGGCTCGGAGAAGGTGCACGGTTCTCCGCTCGGTGCCGA
CGAGATCGCCGCCACCCGCGCGGCGCTGGGCTGGGAGGCTGCGCCCTTCGAGATTCCCGCCGACGTGCTCGCCGGCTGGC
GCGCCGCCGGTGCCGCCGGATCCGCCGCCCGCGCGGCCTGGGAGGCGCGCTTGGCCGCCGCCCCCGAAGCCGACCGGGCC
GAGTTCGAGCGCCGCATCGCCGGCACGCTGCCGCAGGCGCTGGAAGGCGCCATCGTCGCCGTCAAGCAGAAGGCGGTGGC
GGACGGTGGCGCGGTGGCCACCCGCAAGTCGTCCGAGCTGGTGCTGGATTTCATCACCCCGGTGGTGCCGGAGATGCTGG
GCGGCTCGGCCGACCTCACCGGTTCCAACAACACCAAGGCCAAGGGCGCGAAGGCCATCACGCCGGACGATTTCGCCGGC
TCCTTCGTGCACTGGGGCGTGCGCGAGCACGGCATGGCGGCAGCCATGAACGGGATCACCCTGCACAAGGGCCTCATTCC
CTTCTCCGGCGGCTTCCTGGTGTTCTCGGATTATTGCCGCCCCTCCATCCGCCTGGCCGCGCTCATGGGCGAGCGGGTCA
TCCATGTGCTGACCCACGATTCCATCGGCCTTGGCGAAGATGGCCCCACCCATCAGCCGGTGGAGCACCTGGCCGCCCTG
CGCGCCATCCCGAACCTCCTGGTGATGCGCCCCGCCGACACGGTGGAGACGGCCGAGTGCTGGCAGATTGCACTTCAATC
GGAAGGTCGGCCCTCCGCCCTCATCCTGTCGCGGCAGAACCTGCCGATCCTGCGCACCGATGCCACCGCAGAGAACCGCT
CGGCGGGCGGCGCCTATGAGATCGTCGCGGCCTCGGCCAAGGCGCAGGCCAGCCTGTTCGCAACCGGCTCGGAAGTCTCG
CTTGCGGTGGAAGCCGCCAAGCTTCTGGAGGCGCAGGGTGTGCCCACCCGCGTCGTCTCCATCCCTTCGTTCGAACTCTT
CCTCGAAAGGCCTGCCGCAGAGCGGGCCAAGGTGATCGGGGACGCTCCGGCCAAGGTGGCGGTGGAAGCCGCCATCCGCA
TGGGGTGGGACGCCATCGTCGGTTCGGATGCCGCCTTCGTGGGAATGACCTCGTTCGGCGCCTCGGCGCCTGGAAAGGAC
CTTTTCGCCCATTTCGGACTGACCCCGGACAAGGTCGCGGCCAAGGCCCTCGACCAGCTCCGGCAGGTGTGA

Upstream 100 bases:

>100_bases
GGCCAACACTGGCCGGATGACCCTGATGGGTCTGCCACAGCTCGAGGTTGTCTCTGGCAGGGCGGCGCGTCCGGACCCCG
GCGCGGGAGAAACGGAATTC

Downstream 100 bases:

>100_bases
TCATCGGCGCACGGCGGGCGCGACCAGGCCGCACCGCGGGCTCTTCCGCGGGTGCGCAACGCAGTTTCGCAGAGGCCGGG
CTTCAAGCCGGCTCAAGGAG

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 663; Mature: 663

Protein sequence:

>663_residues
MLSRTSHDRMANAIRFLAMDAVEAANSGHPGLPMGAADIATVLFTKVLKYDPTRPFWPDRDRFVLSAGHGSMLLYSVLHL
AGYEKVTIEEIKRFRKLGSLTPGHPENFVTEGIETTTGPLGQGIATAVGMAMAERALAARFGKDVVDHHTFVLCSDGDLM
EGISQEAADLAGHLKLSKLIVMWDDNGISIDGATSISGSTDQLARFAASGWATTRIDGHDPDAILAALTAAKASDRPTLI
ACRTVIGFGSPKKAGSEKVHGSPLGADEIAATRAALGWEAAPFEIPADVLAGWRAAGAAGSAARAAWEARLAAAPEADRA
EFERRIAGTLPQALEGAIVAVKQKAVADGGAVATRKSSELVLDFITPVVPEMLGGSADLTGSNNTKAKGAKAITPDDFAG
SFVHWGVREHGMAAAMNGITLHKGLIPFSGGFLVFSDYCRPSIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAAL
RAIPNLLVMRPADTVETAECWQIALQSEGRPSALILSRQNLPILRTDATAENRSAGGAYEIVAASAKAQASLFATGSEVS
LAVEAAKLLEAQGVPTRVVSIPSFELFLERPAAERAKVIGDAPAKVAVEAAIRMGWDAIVGSDAAFVGMTSFGASAPGKD
LFAHFGLTPDKVAAKALDQLRQV

Sequences:

>Translated_663_residues
MLSRTSHDRMANAIRFLAMDAVEAANSGHPGLPMGAADIATVLFTKVLKYDPTRPFWPDRDRFVLSAGHGSMLLYSVLHL
AGYEKVTIEEIKRFRKLGSLTPGHPENFVTEGIETTTGPLGQGIATAVGMAMAERALAARFGKDVVDHHTFVLCSDGDLM
EGISQEAADLAGHLKLSKLIVMWDDNGISIDGATSISGSTDQLARFAASGWATTRIDGHDPDAILAALTAAKASDRPTLI
ACRTVIGFGSPKKAGSEKVHGSPLGADEIAATRAALGWEAAPFEIPADVLAGWRAAGAAGSAARAAWEARLAAAPEADRA
EFERRIAGTLPQALEGAIVAVKQKAVADGGAVATRKSSELVLDFITPVVPEMLGGSADLTGSNNTKAKGAKAITPDDFAG
SFVHWGVREHGMAAAMNGITLHKGLIPFSGGFLVFSDYCRPSIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAAL
RAIPNLLVMRPADTVETAECWQIALQSEGRPSALILSRQNLPILRTDATAENRSAGGAYEIVAASAKAQASLFATGSEVS
LAVEAAKLLEAQGVPTRVVSIPSFELFLERPAAERAKVIGDAPAKVAVEAAIRMGWDAIVGSDAAFVGMTSFGASAPGKD
LFAHFGLTPDKVAAKALDQLRQV
>Mature_663_residues
MLSRTSHDRMANAIRFLAMDAVEAANSGHPGLPMGAADIATVLFTKVLKYDPTRPFWPDRDRFVLSAGHGSMLLYSVLHL
AGYEKVTIEEIKRFRKLGSLTPGHPENFVTEGIETTTGPLGQGIATAVGMAMAERALAARFGKDVVDHHTFVLCSDGDLM
EGISQEAADLAGHLKLSKLIVMWDDNGISIDGATSISGSTDQLARFAASGWATTRIDGHDPDAILAALTAAKASDRPTLI
ACRTVIGFGSPKKAGSEKVHGSPLGADEIAATRAALGWEAAPFEIPADVLAGWRAAGAAGSAARAAWEARLAAAPEADRA
EFERRIAGTLPQALEGAIVAVKQKAVADGGAVATRKSSELVLDFITPVVPEMLGGSADLTGSNNTKAKGAKAITPDDFAG
SFVHWGVREHGMAAAMNGITLHKGLIPFSGGFLVFSDYCRPSIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAAL
RAIPNLLVMRPADTVETAECWQIALQSEGRPSALILSRQNLPILRTDATAENRSAGGAYEIVAASAKAQASLFATGSEVS
LAVEAAKLLEAQGVPTRVVSIPSFELFLERPAAERAKVIGDAPAKVAVEAAIRMGWDAIVGSDAAFVGMTSFGASAPGKD
LFAHFGLTPDKVAAKALDQLRQV

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=582, Percent_Identity=27.1477663230241, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI4507521, Length=582, Percent_Identity=27.1477663230241, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI133778974, Length=571, Percent_Identity=26.0945709281961, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI225637459, Length=257, Percent_Identity=27.6264591439689, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI225637461, Length=229, Percent_Identity=27.5109170305677, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI225637463, Length=226, Percent_Identity=27.4336283185841, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI48994911, Length=666, Percent_Identity=51.8018018018018, Blast_Score=641, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=660, Percent_Identity=49.6969696969697, Blast_Score=608, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI17539652, Length=602, Percent_Identity=26.9102990033223, Blast_Score=178, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6325331, Length=675, Percent_Identity=44.5925925925926, Blast_Score=499, Evalue=1e-142,
Organism=Saccharomyces cerevisiae, GI6319593, Length=669, Percent_Identity=42.4514200298954, Blast_Score=476, Evalue=1e-135,
Organism=Drosophila melanogaster, GI45551847, Length=581, Percent_Identity=26.6781411359725, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI45550715, Length=581, Percent_Identity=26.6781411359725, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24666278, Length=572, Percent_Identity=26.3986013986014, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24645119, Length=550, Percent_Identity=26.3636363636364, Blast_Score=143, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 69424; Mature: 69424

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRTSHDRMANAIRFLAMDAVEAANSGHPGLPMGAADIATVLFTKVLKYDPTRPFWPDR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSVLHLAGYEKVTIEEIKRFRKLGSLTPGHPENFVTEGIETTTGPL
CCEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCC
GQGIATAVGMAMAERALAARFGKDVVDHHTFVLCSDGDLMEGISQEAADLAGHLKLSKLI
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEEEEEE
VMWDDNGISIDGATSISGSTDQLARFAASGWATTRIDGHDPDAILAALTAAKASDRPTLI
EEECCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
ACRTVIGFGSPKKAGSEKVHGSPLGADEIAATRAALGWEAAPFEIPADVLAGWRAAGAAG
EEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC
SAARAAWEARLAAAPEADRAEFERRIAGTLPQALEGAIVAVKQKAVADGGAVATRKSSEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCHHEEHHHHHHCCCCCEEECCCCHH
VLDFITPVVPEMLGGSADLTGSNNTKAKGAKAITPDDFAGSFVHWGVREHGMAAAMNGIT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCHHHHHCCEE
LHKGLIPFSGGFLVFSDYCRPSIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAAL
EECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHH
RAIPNLLVMRPADTVETAECWQIALQSEGRPSALILSRQNLPILRTDATAENRSAGGAYE
HHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCEE
IVAASAKAQASLFATGSEVSLAVEAAKLLEAQGVPTRVVSIPSFELFLERPAAERAKVIG
EEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHC
DAPAKVAVEAAIRMGWDAIVGSDAAFVGMTSFGASAPGKDLFAHFGLTPDKVAAKALDQL
CCCHHHHHHHHHHHCHHHHCCCCCCEEEEHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
RQV
HCC
>Mature Secondary Structure
MLSRTSHDRMANAIRFLAMDAVEAANSGHPGLPMGAADIATVLFTKVLKYDPTRPFWPDR
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DRFVLSAGHGSMLLYSVLHLAGYEKVTIEEIKRFRKLGSLTPGHPENFVTEGIETTTGPL
CCEEEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCC
GQGIATAVGMAMAERALAARFGKDVVDHHTFVLCSDGDLMEGISQEAADLAGHLKLSKLI
CCHHHHHHHHHHHHHHHHHHHCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHEEEEEEE
VMWDDNGISIDGATSISGSTDQLARFAASGWATTRIDGHDPDAILAALTAAKASDRPTLI
EEECCCCEEECCCCCCCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCEEE
ACRTVIGFGSPKKAGSEKVHGSPLGADEIAATRAALGWEAAPFEIPADVLAGWRAAGAAG
EEEHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCC
SAARAAWEARLAAAPEADRAEFERRIAGTLPQALEGAIVAVKQKAVADGGAVATRKSSEL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHCCHHEEHHHHHHCCCCCEEECCCCHH
VLDFITPVVPEMLGGSADLTGSNNTKAKGAKAITPDDFAGSFVHWGVREHGMAAAMNGIT
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHCCHHHHHCCEE
LHKGLIPFSGGFLVFSDYCRPSIRLAALMGERVIHVLTHDSIGLGEDGPTHQPVEHLAAL
EECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCHHHHHHHHH
RAIPNLLVMRPADTVETAECWQIALQSEGRPSALILSRQNLPILRTDATAENRSAGGAYE
HHHCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCCEEECCCCCCCCCCCCCEE
IVAASAKAQASLFATGSEVSLAVEAAKLLEAQGVPTRVVSIPSFELFLERPAAERAKVIG
EEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHCCCHHHHHHHHC
DAPAKVAVEAAIRMGWDAIVGSDAAFVGMTSFGASAPGKDLFAHFGLTPDKVAAKALDQL
CCCHHHHHHHHHHHCHHHHCCCCCCEEEEHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHH
RQV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7928974 [H]