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The map label for this gene is msrB2 [H]

Identifier: 154246898

GI number: 154246898

Start: 3289482

End: 3289928

Strand: Direct

Name: msrB2 [H]

Synonym: Xaut_2966

Alternate gene names: 154246898

Gene position: 3289482-3289928 (Clockwise)

Preceding gene: 154246897

Following gene: 154246899

Centisome position: 61.96

GC content: 57.27

Gene sequence:

>447_bases
ATGACAGCCTACAAGAAGACAGAAGCTGCTATCGCCAAGCTGTCACCTGAGGAATATCGGGTGACGCAGCAGAGTGCGAC
CGAGCGACCAGGAACCGGTGCGCTTCTCCATAATAAGGAACCCGGCGTTTATGTCGATATCGTCTCAGGCGAACCCCTGT
TCGCATCGTCCGACAAATACGAGTCGGGCTGCGGATGGCCGAGCTTCACCAAGCCGATCGAACCTGCGAACGTGAATGAA
CTACGCGACAACAGCCACGGTATGATCCGGACGGAAGTGCGTTCGACGTATGGCGATAGCCATCTCGGCCACGTTTTCCC
CGACGGGCCGAGCGATCGCGGTGGCCTGCGTTACTGTATCAATTCGGCTTCGCTGCGCTTCGTACCCCGCGGCGAGATGG
AGAGCCAAGGTTACGGTGAATATCTCAACCAGGTGGAGGATATCTGA

Upstream 100 bases:

>100_bases
AGTGCATGCCGGTGACAACATCAAAACTATAGTTGCGGCGTATTGGACACCTTCGGATCGAATATCCATTTTCTCGGGTA
TGAGTTCGAAGGAGGAATCC

Downstream 100 bases:

>100_bases
TGACGACTGAACGCGCTGTTCTCGCCGGCGGCTGCTTCTGGGGCATGCAGGATCTTATCCGCAAGCTGCCCGGTGTAATC
TCCACCCGTGTCGGTTACAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase 2 [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTAYKKTEAAIAKLSPEEYRVTQQSATERPGTGALLHNKEPGVYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPANVNE
LRDNSHGMIRTEVRSTYGDSHLGHVFPDGPSDRGGLRYCINSASLRFVPRGEMESQGYGEYLNQVEDI

Sequences:

>Translated_148_residues
MTAYKKTEAAIAKLSPEEYRVTQQSATERPGTGALLHNKEPGVYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPANVNE
LRDNSHGMIRTEVRSTYGDSHLGHVFPDGPSDRGGLRYCINSASLRFVPRGEMESQGYGEYLNQVEDI
>Mature_147_residues
TAYKKTEAAIAKLSPEEYRVTQQSATERPGTGALLHNKEPGVYVDIVSGEPLFASSDKYESGCGWPSFTKPIEPANVNEL
RDNSHGMIRTEVRSTYGDSHLGHVFPDGPSDRGGLRYCINSASLRFVPRGEMESQGYGEYLNQVEDI

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=117, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI301336162, Length=117, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI73089054, Length=117, Percent_Identity=46.1538461538462, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI37620216, Length=117, Percent_Identity=46.1538461538462, Blast_Score=109, Evalue=8e-25,
Organism=Homo sapiens, GI117606353, Length=125, Percent_Identity=47.2, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1788077, Length=128, Percent_Identity=50.78125, Blast_Score=131, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=115, Percent_Identity=48.695652173913, Blast_Score=115, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=115, Percent_Identity=48.695652173913, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=122, Percent_Identity=39.344262295082, Blast_Score=88, Evalue=5e-19,
Organism=Drosophila melanogaster, GI221378664, Length=117, Percent_Identity=49.5726495726496, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI221378662, Length=124, Percent_Identity=46.7741935483871, Blast_Score=112, Evalue=7e-26,
Organism=Drosophila melanogaster, GI45553335, Length=117, Percent_Identity=49.5726495726496, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21356369, Length=117, Percent_Identity=49.5726495726496, Blast_Score=111, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645799, Length=117, Percent_Identity=49.5726495726496, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645804, Length=128, Percent_Identity=45.3125, Blast_Score=106, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24645801, Length=128, Percent_Identity=45.3125, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16316; Mature: 16185

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYKKTEAAIAKLSPEEYRVTQQSATERPGTGALLHNKEPGVYVDIVSGEPLFASSDKY
CCCCCCHHHHHHHCCHHHHEECHHHCCCCCCCCEEEECCCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKPIEPANVNELRDNSHGMIRTEVRSTYGDSHLGHVFPDGPSDRGGLRYCI
CCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFVPRGEMESQGYGEYLNQVEDI
CCCEEEEEECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TAYKKTEAAIAKLSPEEYRVTQQSATERPGTGALLHNKEPGVYVDIVSGEPLFASSDKY
CCCCCHHHHHHHCCHHHHEECHHHCCCCCCCCEEEECCCCCEEEEEECCCCEEECCCCC
ESGCGWPSFTKPIEPANVNELRDNSHGMIRTEVRSTYGDSHLGHVFPDGPSDRGGLRYCI
CCCCCCCCCCCCCCCCCCCHHCCCCCCEEEEEHHHHCCCCCCCCCCCCCCCCCCCEEEEE
NSASLRFVPRGEMESQGYGEYLNQVEDI
CCCEEEEEECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]