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The map label for this gene is trxB [H]

Identifier: 154246692

GI number: 154246692

Start: 3049179

End: 3050141

Strand: Direct

Name: trxB [H]

Synonym: Xaut_2753

Alternate gene names: 154246692

Gene position: 3049179-3050141 (Clockwise)

Preceding gene: 154246690

Following gene: 154246693

Centisome position: 57.43

GC content: 66.56

Gene sequence:

>963_bases
ATGACTGCCCACACCGTCAAAGTCGTCATCATCGGCTCGGGGCCGGCTGGCTACACCGCGGCCATCTACGCAGCGCGTGC
AATGCTGGAGCCGGTGCTGTTCGAGGGCATCCAGCCCGGCGGCCAGCTCACCATCACCACGGATGTGGAGAATTATCCCG
GCTTCGCCGACCCCATCCAAGGGCCGTGGCTGATGGAGCAGATGCGTGCGCAGGCCGAGCACGTGGGCACCAAGATCGTC
ACCGACCATGTGGCGAGCCTCGACCTGTCGCACCGGCCGTTCCGCATGGTGACCGAATCGGGCGACACCTATGTGGCGGA
TGTGGTGATCCTGGCCACCGGCGCCCAGGCGCGCTGGCTTGGGCTCGAATCGGAGGCGGCCTACCGCGGCTCCGGCGTGT
CCGCCTGCGCCACCTGCGACGGCTTCTTCTATCGCGGCAAGGACGTGGTGGTGGTTGGCGGCGGCAACACGGCAGTGGAA
GAGGCGCTGTTCCTCACCAATTTCGCCTCCAACGTCACCGTCGTGCATCGCCGCGACAGCTTCCGCTCGGAGAAGATCCT
GCAGGAACGGCTGTTCGCCCATCCCAAGGTGAAGGTGGTGTGGAACGCGGAGCTGGCCGAGGTGGTGGGCCAGGACGACC
CCTTCACCAAGGTCACAGGCGCGAAACTGCGTGACGTGCGCACCGGAGTCCTCACCGAGCTACCCGCTGACGGCATATTT
ATCGCAATTGGCCATGCGCCTGCCACAGAGCTGGTAAAAGACCAGCTGAAGCTCAAGGAGAGCGGCTATGTCTGGACCGC
GCCCGATTCGACGGCAACGTCGGTGCCGGGCGTGTTCGCGGCCGGCGACGTGGCGGACGACGTCTATCGTCAGGCCGTCA
CCGCCGCGGGCCGGGGCTGCATGGCCGCTCTCGAGGCGGAGCGCTTCCTGGCCCACCAGGGCGTGGCGAAGGCGGCGGAA
TAA

Upstream 100 bases:

>100_bases
ACATTCGAGCATAGCTCACGCTGCGGCCGGGAGCGCCGGCCCCCGCGGCCGTCGCCGCTCCACATCCTGCCGCGGCACCG
CACGGATTTCGGGGACACTC

Downstream 100 bases:

>100_bases
CCCGTCGCTCGCCCGCGCCGGCGTCCGGCGGCGATCCTGTTTGGCGGGAAGGGTCGGCTGGCCGGGGTGGGTCCTCGGAT
TGTCCGTTCTTCCGCATTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTAHTVKVVIIGSGPAGYTAAIYAARAMLEPVLFEGIQPGGQLTITTDVENYPGFADPIQGPWLMEQMRAQAEHVGTKIV
TDHVASLDLSHRPFRMVTESGDTYVADVVILATGAQARWLGLESEAAYRGSGVSACATCDGFFYRGKDVVVVGGGNTAVE
EALFLTNFASNVTVVHRRDSFRSEKILQERLFAHPKVKVVWNAELAEVVGQDDPFTKVTGAKLRDVRTGVLTELPADGIF
IAIGHAPATELVKDQLKLKESGYVWTAPDSTATSVPGVFAAGDVADDVYRQAVTAAGRGCMAALEAERFLAHQGVAKAAE

Sequences:

>Translated_320_residues
MTAHTVKVVIIGSGPAGYTAAIYAARAMLEPVLFEGIQPGGQLTITTDVENYPGFADPIQGPWLMEQMRAQAEHVGTKIV
TDHVASLDLSHRPFRMVTESGDTYVADVVILATGAQARWLGLESEAAYRGSGVSACATCDGFFYRGKDVVVVGGGNTAVE
EALFLTNFASNVTVVHRRDSFRSEKILQERLFAHPKVKVVWNAELAEVVGQDDPFTKVTGAKLRDVRTGVLTELPADGIF
IAIGHAPATELVKDQLKLKESGYVWTAPDSTATSVPGVFAAGDVADDVYRQAVTAAGRGCMAALEAERFLAHQGVAKAAE
>Mature_319_residues
TAHTVKVVIIGSGPAGYTAAIYAARAMLEPVLFEGIQPGGQLTITTDVENYPGFADPIQGPWLMEQMRAQAEHVGTKIVT
DHVASLDLSHRPFRMVTESGDTYVADVVILATGAQARWLGLESEAAYRGSGVSACATCDGFFYRGKDVVVVGGGNTAVEE
ALFLTNFASNVTVVHRRDSFRSEKILQERLFAHPKVKVVWNAELAEVVGQDDPFTKVTGAKLRDVRTGVLTELPADGIFI
AIGHAPATELVKDQLKLKESGYVWTAPDSTATSVPGVFAAGDVADDVYRQAVTAAGRGCMAALEAERFLAHQGVAKAAE

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=325, Percent_Identity=53.5384615384615, Blast_Score=332, Evalue=1e-92,
Organism=Escherichia coli, GI87081763, Length=307, Percent_Identity=33.2247557003257, Blast_Score=134, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=47.9495268138801, Blast_Score=300, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=46.1783439490446, Blast_Score=288, Evalue=1e-78,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34093; Mature: 33962

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHTVKVVIIGSGPAGYTAAIYAARAMLEPVLFEGIQPGGQLTITTDVENYPGFADPIQ
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
GPWLMEQMRAQAEHVGTKIVTDHVASLDLSHRPFRMVTESGDTYVADVVILATGAQARWL
CHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEE
GLESEAAYRGSGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFASNVTVVHRRDS
CCCCCCCCCCCCCCEEEECCCEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCC
FRSEKILQERLFAHPKVKVVWNAELAEVVGQDDPFTKVTGAKLRDVRTGVLTELPADGIF
HHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
IAIGHAPATELVKDQLKLKESGYVWTAPDSTATSVPGVFAAGDVADDVYRQAVTAAGRGC
EEECCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCHH
MAALEAERFLAHQGVAKAAE
HHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
TAHTVKVVIIGSGPAGYTAAIYAARAMLEPVLFEGIQPGGQLTITTDVENYPGFADPIQ
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCC
GPWLMEQMRAQAEHVGTKIVTDHVASLDLSHRPFRMVTESGDTYVADVVILATGAQARWL
CHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEEEECCCCEEEE
GLESEAAYRGSGVSACATCDGFFYRGKDVVVVGGGNTAVEEALFLTNFASNVTVVHRRDS
CCCCCCCCCCCCCCEEEECCCEEECCCEEEEECCCCHHHHHHHHHHHCCCCEEEEEECCC
FRSEKILQERLFAHPKVKVVWNAELAEVVGQDDPFTKVTGAKLRDVRTGVLTELPADGIF
HHHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEE
IAIGHAPATELVKDQLKLKESGYVWTAPDSTATSVPGVFAAGDVADDVYRQAVTAAGRGC
EEECCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCHH
MAALEAERFLAHQGVAKAAE
HHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA