Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 154246693

GI number: 154246693

Start: 3050421

End: 3051311

Strand: Direct

Name: yafC [H]

Synonym: Xaut_2754

Alternate gene names: 154246693

Gene position: 3050421-3051311 (Clockwise)

Preceding gene: 154246692

Following gene: 154246694

Centisome position: 57.46

GC content: 64.65

Gene sequence:

>891_bases
ATGGATTGGGACAAGCTTAAGGTCTTCCACGTCGCCGCCGAAGCGGGTTCGTTTACCCATGCGGGCGAGACGCTCGGCCT
CTCCCAGTCGGCCGTGAGCCGGCAAGTCTCAGCCCTGGAGACGGAGCTGAAGGTTCCGCTGTTCCATCGCCATGCGCGTG
GCCTCATCCTCACCGAGCAGGGCGAGCTGCTGTATCGCACCGCCCACGAGGTGTTCCTGAAGCTGGAATCGGCGCGCGCC
CAGCTTACCGACAGCCGCGAGAAGCCCAACGGTGAATTGCGCGTCACCACCACGGTGGGGCTCGGCACCCATTGGCTGAC
GGCGCGGGTGGGTGAGTTTGTGGAGCTGTTCCCGGACATCCGCATCCAGCTCATCCTCACCGACGAGGAGCTGGATCTCG
CCATGCGCGAGGCGGACGTGGCCATCCGCATGCGCCAGCCGGTGCAGCCGGATCTGGTGCAGCGCCGGCTGTTCACGGTG
CATTTCCATGCCTACGCGTCGGCCGATTATCTCAAGCGGCATGGCCATCCCCGCTCCATCGATGAGCTGGACAAGCACCG
CATCCTATTGCTCGGCGGGCCGATCCCGCCCTATTTCCAGGGGCTGAACTGGCTCGAGCATGCCGGGCGCGACGGCTCGA
CGCCCCGTGTGCCGGCCTTCGAGGTCAACAGCGTGCTGGGCCTGAAGCGGGCGGTGGAGCGCGGCGTGGGCATCGGCACG
CTGCCCGACTACCTATCGGATGATGCCTCGTCGCTGGTGCAGCTGTTCACCGACCGCGAGACGCCCAAACTTGAGGCATA
CTTTACCTATGCGCAAGAAATGCGCTCCGTGGCTCGGATTCAGGTCTTCCGAGACTTCCTGATCTCCAAGGCGCAGCGGT
GGAATTACTGA

Upstream 100 bases:

>100_bases
AAGCGAGCCACCCAACGGGCGCGATCCGTCCCCTTGAAGGGTGAGTGGGCGATTCTGCGTTCAGAAGGACGCCGGCGCGC
TCCAAAGGGGCTCGGGCCTG

Downstream 100 bases:

>100_bases
TTTATGACGAGTAATGGTATTATGCTAACGATAGCGTATGCCAGCCAAGCGCTGGGCACATGCCTGATATGCAGCCATTC
TCCGTTGCAAACTGCCTAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALETELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELFPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRRLFTV
HFHAYASADYLKRHGHPRSIDELDKHRILLLGGPIPPYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDASSLVQLFTDRETPKLEAYFTYAQEMRSVARIQVFRDFLISKAQRWNY

Sequences:

>Translated_296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALETELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELFPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRRLFTV
HFHAYASADYLKRHGHPRSIDELDKHRILLLGGPIPPYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDASSLVQLFTDRETPKLEAYFTYAQEMRSVARIQVFRDFLISKAQRWNY
>Mature_296_residues
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALETELKVPLFHRHARGLILTEQGELLYRTAHEVFLKLESARA
QLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELFPDIRIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRRLFTV
HFHAYASADYLKRHGHPRSIDELDKHRILLLGGPIPPYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
LPDYLSDDASSLVQLFTDRETPKLEAYFTYAQEMRSVARIQVFRDFLISKAQRWNY

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=290, Percent_Identity=33.448275862069, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87081978, Length=188, Percent_Identity=28.1914893617021, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787128, Length=307, Percent_Identity=28.0130293159609, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789440, Length=186, Percent_Identity=28.494623655914, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789639, Length=251, Percent_Identity=27.0916334661355, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789173, Length=295, Percent_Identity=27.1186440677966, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI145693193, Length=293, Percent_Identity=26.6211604095563, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787589, Length=269, Percent_Identity=27.8810408921933, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788706, Length=291, Percent_Identity=24.3986254295533, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=246, Percent_Identity=28.0487804878049, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786448, Length=142, Percent_Identity=31.6901408450704, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790011, Length=199, Percent_Identity=25.1256281407035, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788748, Length=139, Percent_Identity=33.0935251798561, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788481, Length=126, Percent_Identity=31.7460317460317, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33624; Mature: 33624

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALETELKVPLFHRHARGLILTEQ
CCCHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECC
GELLYRTAHEVFLKLESARAQLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELFPDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRRLFTVHFHAYASADYLKRHGHPRSI
EEEEEEECCHHHHHHHHHHHHEEECCCCCHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCH
DELDKHRILLLGGPIPPYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
HHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LPDYLSDDASSLVQLFTDRETPKLEAYFTYAQEMRSVARIQVFRDFLISKAQRWNY
CCHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDWDKLKVFHVAAEAGSFTHAGETLGLSQSAVSRQVSALETELKVPLFHRHARGLILTEQ
CCCHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCEEEECC
GELLYRTAHEVFLKLESARAQLTDSREKPNGELRVTTTVGLGTHWLTARVGEFVELFPDI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCC
RIQLILTDEELDLAMREADVAIRMRQPVQPDLVQRRLFTVHFHAYASADYLKRHGHPRSI
EEEEEEECCHHHHHHHHHHHHEEECCCCCHHHHHHHHHEEEEEHHHHHHHHHHCCCCCCH
DELDKHRILLLGGPIPPYFQGLNWLEHAGRDGSTPRVPAFEVNSVLGLKRAVERGVGIGT
HHHCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
LPDYLSDDASSLVQLFTDRETPKLEAYFTYAQEMRSVARIQVFRDFLISKAQRWNY
CCHHHCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]