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The map label for this gene is yggV [C]

Identifier: 154246477

GI number: 154246477

Start: 2832817

End: 2833452

Strand: Direct

Name: yggV [C]

Synonym: Xaut_2536

Alternate gene names: 154246477

Gene position: 2832817-2833452 (Clockwise)

Preceding gene: 154246476

Following gene: 154246478

Centisome position: 53.36

GC content: 69.65

Gene sequence:

>636_bases
ATGGACCATCGCATCCTCAAGGGCCGGCTCGTGGTGGCCACCCACAATCCCGGCAAGCTCATCGAGATGCGCATGCTGCT
CGCCCCCCACGGGGTGGAGGCGGTCTCGGCCGGGGAATTGGGCCTCACCGAGCCGGAGGAGACGGAAGAAACCTTCTCCG
GCAATGCCCGGCTGAAGGCGCAGGCGGCGGCTCAGGCGGCGAACCTGCCGGCCTTCGCCGACGATTCGGGCCTCGTCATC
GATGCGCTGGGCGGCGCGCCGGGCATCCACACCGCCCGCTGGGCGGGGCCTGACCGGGACTTCGAGATGGCCATGGAGAA
GGTTGAGGCCGAGCTGGAGAAGGTGGGCGCCATCGCCCCCGAGCAGCGCCGCGCCCGCTTCGTCTCCGCTTTGTGCCTCG
CGTGGCCCGACGGGCACGTGGAGGAGTTCGAGGGCGTCGTGGAGGGCACCTTGGTGTGGCCGCCGCGCGGCGCCAAGGGC
TTCGGCTACGATCCCATGTTCATCCCGGAGGACTATCCCAAGACCTTCGCGGAGATGACGGCGGACGAGAAGCATTCCAT
GCCGCCCAAGGGCTTCGGCCTCTCGCACCGGGCGCGGGCCTTCCTGAAGCTGTCGCAGGCGTGTCTGGAGGGGTGA

Upstream 100 bases:

>100_bases
AAAAGACCCCGTTCTCGCAGGACGAACTGCTGGGCCTTTTGTCCCTCGCCCGTTCCGGCGTGGAGAAGCTGGTGGGGCTG
CAGAAGCTGGCGGTGGGCTG

Downstream 100 bases:

>100_bases
GCGAAGACTTGGATCAGGCTTCCTCCGATAGGACCAACGTGAACCCTCTCCCGCCTGAGGCCGAATCTGTTCGGCCTCAG
GCCGTGGCAACCGAACTTGG

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDHRILKGRLVVATHNPGKLIEMRMLLAPHGVEAVSAGELGLTEPEETEETFSGNARLKAQAAAQAANLPAFADDSGLVI
DALGGAPGIHTARWAGPDRDFEMAMEKVEAELEKVGAIAPEQRRARFVSALCLAWPDGHVEEFEGVVEGTLVWPPRGAKG
FGYDPMFIPEDYPKTFAEMTADEKHSMPPKGFGLSHRARAFLKLSQACLEG

Sequences:

>Translated_211_residues
MDHRILKGRLVVATHNPGKLIEMRMLLAPHGVEAVSAGELGLTEPEETEETFSGNARLKAQAAAQAANLPAFADDSGLVI
DALGGAPGIHTARWAGPDRDFEMAMEKVEAELEKVGAIAPEQRRARFVSALCLAWPDGHVEEFEGVVEGTLVWPPRGAKG
FGYDPMFIPEDYPKTFAEMTADEKHSMPPKGFGLSHRARAFLKLSQACLEG
>Mature_211_residues
MDHRILKGRLVVATHNPGKLIEMRMLLAPHGVEAVSAGELGLTEPEETEETFSGNARLKAQAAAQAANLPAFADDSGLVI
DALGGAPGIHTARWAGPDRDFEMAMEKVEAELEKVGAIAPEQRRARFVSALCLAWPDGHVEEFEGVVEGTLVWPPRGAKG
FGYDPMFIPEDYPKTFAEMTADEKHSMPPKGFGLSHRARAFLKLSQACLEG

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=208, Percent_Identity=28.8461538461538, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI31657144, Length=150, Percent_Identity=32, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1789324, Length=208, Percent_Identity=39.4230769230769, Blast_Score=126, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322529, Length=212, Percent_Identity=27.8301886792453, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920712, Length=202, Percent_Identity=30.6930693069307, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22817; Mature: 22817

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHRILKGRLVVATHNPGKLIEMRMLLAPHGVEAVSAGELGLTEPEETEETFSGNARLKA
CCCCEEECEEEEEECCCCCEEHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHCCCCEEEH
QAAAQAANLPAFADDSGLVIDALGGAPGIHTARWAGPDRDFEMAMEKVEAELEKVGAIAP
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EQRRARFVSALCLAWPDGHVEEFEGVVEGTLVWPPRGAKGFGYDPMFIPEDYPKTFAEMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
ADEKHSMPPKGFGLSHRARAFLKLSQACLEG
CCHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDHRILKGRLVVATHNPGKLIEMRMLLAPHGVEAVSAGELGLTEPEETEETFSGNARLKA
CCCCEEECEEEEEECCCCCEEHHHHHHCCCCCCEECCCCCCCCCCHHHHHHHCCCCEEEH
QAAAQAANLPAFADDSGLVIDALGGAPGIHTARWAGPDRDFEMAMEKVEAELEKVGAIAP
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCC
EQRRARFVSALCLAWPDGHVEEFEGVVEGTLVWPPRGAKGFGYDPMFIPEDYPKTFAEMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHH
ADEKHSMPPKGFGLSHRARAFLKLSQACLEG
CCHHCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA