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The map label for this gene is yggW [H]

Identifier: 154246478

GI number: 154246478

Start: 2833536

End: 2834735

Strand: Direct

Name: yggW [H]

Synonym: Xaut_2537

Alternate gene names: 154246478

Gene position: 2833536-2834735 (Clockwise)

Preceding gene: 154246477

Following gene: 154246479

Centisome position: 53.37

GC content: 71.5

Gene sequence:

>1200_bases
GTGGCAACCGAACTTGGCAACAGCCGAGTTTGGGCGGGAGAGGGAGCCTCGCCCGTACCCGACCCTGCGGGCTTCGGCGT
CTATGTCCATTGGCCGTTCTGCAAGGCCAAGTGCCCCTATTGCGACTTCAACAGCCATGTGCGCCACGCCCCGCCGGACG
AGGCGCGCTTCATCGCCGCCTTCCGCCGCGAGATCGCGCACATGCGCGCCTTGTCCGGCCCGAAGCAGGCGCAGACGGTG
TTCTTCGGCGGTGGCACGCCCTCGCTCATGGCGCCGGCCACGGTGGCCGCCATCCTCGAGGCCATTAACGCCGCCTGGCC
GCTCACCGCCGATGCCGAGGTGACGCTGGAGGCCAATCCCACCTCGGTGGAGGCGGAACGCTTCGCCGGCTATGGCGCGG
CGGGGGTCAACCGGGTGTCCTTGGGGGTGCAGGCGCTGCATGACGCCGATTTGCAGGGCCTCGGCCGCATGCATTCGGTA
GCCGAGGCCCTGGCCGCGGTGGCCATCGCCCGCCGGGCGTTCAGGCGGGTCTCCTTCGACCTCATCTATGCCCGCCCGCG
CCAGACCCCCGAGGGCTGGGCGGCGGAGCTGAGGCGCGCCCTGGCCGAGGGCTGCGAGCATCTCTCCCTCTACCAGCTCA
CCATCGAGCCCGGCACGCCGTTCGAGCGGCTCTATGGCGCCGGCAAGCTGATCCTGCCCGACGACGACATTTCCCGCGCC
CTGTGGGACGTGACGCAGGAGGTGACGGCTCAGGCCGGCCTGCCCGCCTACGAGGTCTCCAACCACGCCCGTCCGGGCGC
GGAGGCGCGGCACAACCAGATCTACTGGCGCTACGGCACCTATGCCGGCATCGGCGCCGGCGCCCACGGCCGGCTTGTGG
TGGACGGCACCCGCCGCGCCCTCTTCACCGAGCGTGCGCCGGAAGACTGGCTGGCGCGGGTGGAGGCGCACGGGCACGGC
ATCGTCTCCGACGAGGCCCTGTCGGCGGCCGAGCAGGCGGACGAGATGCTGCTCATGGGCCTGCGCCTGAAGGAGGGCGT
GGATCTTGCCCGCCATGCCCGCCTCGGCGGCCGGGTGGATGAGGCGCGCATCGCTGCTTTGGCGGCGGCGGGTTTCGTCA
CCCGCACCGGTGACCGGCTGGCGGTGACGCCCGCCGGCTTCCCGGTGCTCAATGCAGTGATCGCGCAACTGGCGCAGTGA

Upstream 100 bases:

>100_bases
CGTGTCTGGAGGGGTGAGCGAAGACTTGGATCAGGCTTCCTCCGATAGGACCAACGTGAACCCTCTCCCGCCTGAGGCCG
AATCTGTTCGGCCTCAGGCC

Downstream 100 bases:

>100_bases
GGCCGGCGCGGTTCACGCCTGCGGGGTCCCGGCGTTATAAGGCTGTCCGGTATCAAGGCGCGTTTGCCATGCGGCGCGCC
GGTCCAACGAGGCGGAAATG

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 398

Protein sequence:

>399_residues
MATELGNSRVWAGEGASPVPDPAGFGVYVHWPFCKAKCPYCDFNSHVRHAPPDEARFIAAFRREIAHMRALSGPKQAQTV
FFGGGTPSLMAPATVAAILEAINAAWPLTADAEVTLEANPTSVEAERFAGYGAAGVNRVSLGVQALHDADLQGLGRMHSV
AEALAAVAIARRAFRRVSFDLIYARPRQTPEGWAAELRRALAEGCEHLSLYQLTIEPGTPFERLYGAGKLILPDDDISRA
LWDVTQEVTAQAGLPAYEVSNHARPGAEARHNQIYWRYGTYAGIGAGAHGRLVVDGTRRALFTERAPEDWLARVEAHGHG
IVSDEALSAAEQADEMLLMGLRLKEGVDLARHARLGGRVDEARIAALAAAGFVTRTGDRLAVTPAGFPVLNAVIAQLAQ

Sequences:

>Translated_399_residues
MATELGNSRVWAGEGASPVPDPAGFGVYVHWPFCKAKCPYCDFNSHVRHAPPDEARFIAAFRREIAHMRALSGPKQAQTV
FFGGGTPSLMAPATVAAILEAINAAWPLTADAEVTLEANPTSVEAERFAGYGAAGVNRVSLGVQALHDADLQGLGRMHSV
AEALAAVAIARRAFRRVSFDLIYARPRQTPEGWAAELRRALAEGCEHLSLYQLTIEPGTPFERLYGAGKLILPDDDISRA
LWDVTQEVTAQAGLPAYEVSNHARPGAEARHNQIYWRYGTYAGIGAGAHGRLVVDGTRRALFTERAPEDWLARVEAHGHG
IVSDEALSAAEQADEMLLMGLRLKEGVDLARHARLGGRVDEARIAALAAAGFVTRTGDRLAVTPAGFPVLNAVIAQLAQ
>Mature_398_residues
ATELGNSRVWAGEGASPVPDPAGFGVYVHWPFCKAKCPYCDFNSHVRHAPPDEARFIAAFRREIAHMRALSGPKQAQTVF
FGGGTPSLMAPATVAAILEAINAAWPLTADAEVTLEANPTSVEAERFAGYGAAGVNRVSLGVQALHDADLQGLGRMHSVA
EALAAVAIARRAFRRVSFDLIYARPRQTPEGWAAELRRALAEGCEHLSLYQLTIEPGTPFERLYGAGKLILPDDDISRAL
WDVTQEVTAQAGLPAYEVSNHARPGAEARHNQIYWRYGTYAGIGAGAHGRLVVDGTRRALFTERAPEDWLARVEAHGHGI
VSDEALSAAEQADEMLLMGLRLKEGVDLARHARLGGRVDEARIAALAAAGFVTRTGDRLAVTPAGFPVLNAVIAQLAQ

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=313, Percent_Identity=45.3674121405751, Blast_Score=253, Evalue=2e-67,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=35.978835978836, Blast_Score=236, Evalue=1e-63,
Organism=Escherichia coli, GI87082341, Length=250, Percent_Identity=28.4, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42794; Mature: 42663

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATELGNSRVWAGEGASPVPDPAGFGVYVHWPFCKAKCPYCDFNSHVRHAPPDEARFIAA
CCCCCCCCEEECCCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCCCCCHHHHHHHH
FRREIAHMRALSGPKQAQTVFFGGGTPSLMAPATVAAILEAINAAWPLTADAEVTLEANP
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
TSVEAERFAGYGAAGVNRVSLGVQALHDADLQGLGRMHSVAEALAAVAIARRAFRRVSFD
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
LIYARPRQTPEGWAAELRRALAEGCEHLSLYQLTIEPGTPFERLYGAGKLILPDDDISRA
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHCCCEEEECCCHHHHH
LWDVTQEVTAQAGLPAYEVSNHARPGAEARHNQIYWRYGTYAGIGAGAHGRLVVDGTRRA
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEECCEECCCCCCCCEEEECCCCHH
LFTERAPEDWLARVEAHGHGIVSDEALSAAEQADEMLLMGLRLKEGVDLARHARLGGRVD
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
EARIAALAAAGFVTRTGDRLAVTPAGFPVLNAVIAQLAQ
HHHHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ATELGNSRVWAGEGASPVPDPAGFGVYVHWPFCKAKCPYCDFNSHVRHAPPDEARFIAA
CCCCCCCEEECCCCCCCCCCCCCCEEEEECCHHCCCCCCCCCCCCCCCCCCHHHHHHHH
FRREIAHMRALSGPKQAQTVFFGGGTPSLMAPATVAAILEAINAAWPLTADAEVTLEANP
HHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCC
TSVEAERFAGYGAAGVNRVSLGVQALHDADLQGLGRMHSVAEALAAVAIARRAFRRVSFD
CCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEE
LIYARPRQTPEGWAAELRRALAEGCEHLSLYQLTIEPGTPFERLYGAGKLILPDDDISRA
EEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHCCCEEEECCCHHHHH
LWDVTQEVTAQAGLPAYEVSNHARPGAEARHNQIYWRYGTYAGIGAGAHGRLVVDGTRRA
HHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCEEEEEECCEECCCCCCCCEEEECCCCHH
LFTERAPEDWLARVEAHGHGIVSDEALSAAEQADEMLLMGLRLKEGVDLARHARLGGRVD
HHHCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
EARIAALAAAGFVTRTGDRLAVTPAGFPVLNAVIAQLAQ
HHHHHHHHHHHHHEECCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]