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The map label for this gene is dctD [H]

Identifier: 154245720

GI number: 154245720

Start: 2002604

End: 2003971

Strand: Direct

Name: dctD [H]

Synonym: Xaut_1776

Alternate gene names: 154245720

Gene position: 2002604-2003971 (Clockwise)

Preceding gene: 154245719

Following gene: 154245730

Centisome position: 37.72

GC content: 70.47

Gene sequence:

>1368_bases
ATGAGCGATGTCGCCTTCATCGACGATGACGACCTGCTGCGCGCCGCCAATGTGCAGGCGCTGATGCTGGCCGACCTCAC
CGTCACCGGCTACGGCTCGGCGCTGGCCGCGCTGGAGGAGATCGGCGCCGACTTTCCCGGCGTCGTGGTCAGCGACGTGC
GCATGCCGGGGATCGACGGGCTGGAATTGTTCCGGCGGCTGCGGCGGATTGATCCCGACCTGCCGGTCATCCTCATCACC
GGCCACGGCGACATCGCCATGGCGGTGGATGCCATGCGCGAGGGCGCCTACGATTTCCTCGCCAAGCCCTATGCCAACGA
CCGCCTCCTCACCAGCGTGCGCCACGCCCTCGACCGCCGGCGCCTGGTGCTGGAAAACCGCGACCTGAAGCGCTCGGTGG
AGGCGGCAAGCGAGGACATGCCCCTTTTGGGCACCACCCCGGTGATGGCGCGCATGCGCCAGATGCTACGCCAGATCGCC
GATGCCGACGTAGACGTGCTGGTGGAGGGCGAGACCGGCTCCGGCAAGGAGGTGGTGGCGAATGCGCTCCACCGCTGGAG
CCGCCGCGCCGCACGGCCGTTCGTCGCGGTCAATTGCGGCGCGCTGCCGGAAAACGTCATCGAGAGCGAATTGTTCGGCT
ACGAGGCCGGCGCCTTCACCGGCGCGCTCAAGAAGCGGGTCGGGCGCATCGAGCACGCCAATGGCGGCACCCTCTTTCTC
GACGAGATCGAGGCCATGTCGCCAGCCTTGCAGGTGAAGCTGCTGCGGGTTCTGGAAGCCCGCGAGATCGCGCCGCTCGG
CACCAACGACACCCGGCGCGTGGACATCCGCGTGGTAGCCGCCTCCAAGGTGGACCTGCCGGCGCTGGTGCGCCAGGGCG
CCTTCCGGGAGGACCTCTATTATCGCCTGCACGTGGCCGGCGTGCGGATTCCCGCCCTGCGGGAGCGGCGGGCGGACGTG
CCGCTGCTGTTCGGCCATTTCCTCGCCCGCGCGGCCGAGCGCTTCAACCGGCCGCCGCCGGAGCTCGACGCCGCCGTGCG
CAAGCATCTGGCCGAGCACGACTGGCCCGGCAACGTGCGCGAGCTGGTGCATTATGCCGAGCGGGTGGCACTGGGGCTGG
TGGACGACCTCACGGCGGACGTCGGGGCGGATCTGGGCGCGCCGGGCGGGCTGACGGACGGCACGCTTCCGGAGCGGGTG
GACCGTTTCGAGGCCGGCGAGATCCGCGCCGCGCTGGAAGCCAACCAGGGCGACATCCAGGCCACGGTGGCGGCCCTCGG
CATTCCGCGCAAGACCTTCTACGACAAGCTGCGCCGCCACGGCATCGACCAGTCCGCCTACCGCCCCACCCGCCAGACCG
CGCGGTGA

Upstream 100 bases:

>100_bases
CCAAGGACATCATCACCGAATCCGGCGGTACGCTGGCCGTGGCCAATGCGGGCGGCGCCGTCTTCACCATCACCTTACCA
AGGGCATCCGAGGCAACCTC

Downstream 100 bases:

>100_bases
GGGTGGCCGCCTTCAGAAGCTAACGCCCCCCTCTCCCGCGTGCGAGGGGGGTTCCCACCGTCCCTCGGCGAGACGACGAC
CTCAAAACCTCAGGTCCCCT

Product: two component sigma54 specific Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSDVAFIDDDDLLRAANVQALMLADLTVTGYGSALAALEEIGADFPGVVVSDVRMPGIDGLELFRRLRRIDPDLPVILIT
GHGDIAMAVDAMREGAYDFLAKPYANDRLLTSVRHALDRRRLVLENRDLKRSVEAASEDMPLLGTTPVMARMRQMLRQIA
DADVDVLVEGETGSGKEVVANALHRWSRRAARPFVAVNCGALPENVIESELFGYEAGAFTGALKKRVGRIEHANGGTLFL
DEIEAMSPALQVKLLRVLEAREIAPLGTNDTRRVDIRVVAASKVDLPALVRQGAFREDLYYRLHVAGVRIPALRERRADV
PLLFGHFLARAAERFNRPPPELDAAVRKHLAEHDWPGNVRELVHYAERVALGLVDDLTADVGADLGAPGGLTDGTLPERV
DRFEAGEIRAALEANQGDIQATVAALGIPRKTFYDKLRRHGIDQSAYRPTRQTAR

Sequences:

>Translated_455_residues
MSDVAFIDDDDLLRAANVQALMLADLTVTGYGSALAALEEIGADFPGVVVSDVRMPGIDGLELFRRLRRIDPDLPVILIT
GHGDIAMAVDAMREGAYDFLAKPYANDRLLTSVRHALDRRRLVLENRDLKRSVEAASEDMPLLGTTPVMARMRQMLRQIA
DADVDVLVEGETGSGKEVVANALHRWSRRAARPFVAVNCGALPENVIESELFGYEAGAFTGALKKRVGRIEHANGGTLFL
DEIEAMSPALQVKLLRVLEAREIAPLGTNDTRRVDIRVVAASKVDLPALVRQGAFREDLYYRLHVAGVRIPALRERRADV
PLLFGHFLARAAERFNRPPPELDAAVRKHLAEHDWPGNVRELVHYAERVALGLVDDLTADVGADLGAPGGLTDGTLPERV
DRFEAGEIRAALEANQGDIQATVAALGIPRKTFYDKLRRHGIDQSAYRPTRQTAR
>Mature_454_residues
SDVAFIDDDDLLRAANVQALMLADLTVTGYGSALAALEEIGADFPGVVVSDVRMPGIDGLELFRRLRRIDPDLPVILITG
HGDIAMAVDAMREGAYDFLAKPYANDRLLTSVRHALDRRRLVLENRDLKRSVEAASEDMPLLGTTPVMARMRQMLRQIAD
ADVDVLVEGETGSGKEVVANALHRWSRRAARPFVAVNCGALPENVIESELFGYEAGAFTGALKKRVGRIEHANGGTLFLD
EIEAMSPALQVKLLRVLEAREIAPLGTNDTRRVDIRVVAASKVDLPALVRQGAFREDLYYRLHVAGVRIPALRERRADVP
LLFGHFLARAAERFNRPPPELDAAVRKHLAEHDWPGNVRELVHYAERVALGLVDDLTADVGADLGAPGGLTDGTLPERVD
RFEAGEIRAALEANQGDIQATVAALGIPRKTFYDKLRRHGIDQSAYRPTRQTAR

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=453, Percent_Identity=38.1898454746137, Blast_Score=300, Evalue=9e-83,
Organism=Escherichia coli, GI1788905, Length=402, Percent_Identity=40.0497512437811, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1790437, Length=444, Percent_Identity=38.5135135135135, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1790299, Length=407, Percent_Identity=39.0663390663391, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1789233, Length=323, Percent_Identity=39.938080495356, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI1786524, Length=321, Percent_Identity=41.4330218068536, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789087, Length=343, Percent_Identity=38.7755102040816, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI87082117, Length=313, Percent_Identity=40.8945686900958, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI87082152, Length=233, Percent_Identity=47.2103004291845, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=37.1069182389937, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787583, Length=312, Percent_Identity=35.5769230769231, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI87081858, Length=317, Percent_Identity=35.6466876971609, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1789828, Length=240, Percent_Identity=34.1666666666667, Blast_Score=118, Evalue=9e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49971; Mature: 49840

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVAFIDDDDLLRAANVQALMLADLTVTGYGSALAALEEIGADFPGVVVSDVRMPGIDG
CCCCCCCCCCHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCEEEECCCCCCCCH
LELFRRLRRIDPDLPVILITGHGDIAMAVDAMREGAYDFLAKPYANDRLLTSVRHALDRR
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHH
RLVLENRDLKRSVEAASEDMPLLGTTPVMARMRQMLRQIADADVDVLVEGETGSGKEVVA
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
NALHRWSRRAARPFVAVNCGALPENVIESELFGYEAGAFTGALKKRVGRIEHANGGTLFL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEE
DEIEAMSPALQVKLLRVLEAREIAPLGTNDTRRVDIRVVAASKVDLPALVRQGAFREDLY
HHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHE
YRLHVAGVRIPALRERRADVPLLFGHFLARAAERFNRPPPELDAAVRKHLAEHDWPGNVR
EEEEECCEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
ELVHYAERVALGLVDDLTADVGADLGAPGGLTDGTLPERVDRFEAGEIRAALEANQGDIQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCHHH
ATVAALGIPRKTFYDKLRRHGIDQSAYRPTRQTAR
HHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHCCC
>Mature Secondary Structure 
SDVAFIDDDDLLRAANVQALMLADLTVTGYGSALAALEEIGADFPGVVVSDVRMPGIDG
CCCCCCCCCHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHCCCCCCEEEECCCCCCCCH
LELFRRLRRIDPDLPVILITGHGDIAMAVDAMREGAYDFLAKPYANDRLLTSVRHALDRR
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHHHHH
RLVLENRDLKRSVEAASEDMPLLGTTPVMARMRQMLRQIADADVDVLVEGETGSGKEVVA
HHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
NALHRWSRRAARPFVAVNCGALPENVIESELFGYEAGAFTGALKKRVGRIEHANGGTLFL
HHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEE
DEIEAMSPALQVKLLRVLEAREIAPLGTNDTRRVDIRVVAASKVDLPALVRQGAFREDLY
HHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCCHHHHHHCCCHHHHHE
YRLHVAGVRIPALRERRADVPLLFGHFLARAAERFNRPPPELDAAVRKHLAEHDWPGNVR
EEEEECCEECHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHH
ELVHYAERVALGLVDDLTADVGADLGAPGGLTDGTLPERVDRFEAGEIRAALEANQGDIQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCCCCHHH
ATVAALGIPRKTFYDKLRRHGIDQSAYRPTRQTAR
HHHHHHCCCHHHHHHHHHHCCCCHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]