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The map label for this gene is dctB [H]

Identifier: 154245719

GI number: 154245719

Start: 2000760

End: 2002607

Strand: Direct

Name: dctB [H]

Synonym: Xaut_1775

Alternate gene names: 154245719

Gene position: 2000760-2002607 (Clockwise)

Preceding gene: 154245716

Following gene: 154245720

Centisome position: 37.69

GC content: 71.86

Gene sequence:

>1848_bases
GTGGACGCGTCTCCCAGCGCGGATCGTCCGGCGCGCCGGCGGCCCATCCTCGTGGCGGCGGGGGTGGTGGCGGCCATCGC
CCTCACTCTGCTGGGCCTCGACCGGGTGGCCGACTATGCCGCGCGCCGCTGGGCCCTCGCCCAGGTGGAGTCGAGCGCGG
CCACCGCCGCCGCCCTGCGCGTGGCGGTGCTGCGCTCCGAGATCGAGAAGCAGCGCTCCCTGCCCCTCGCCCTGGCCCAG
GACCCGGACGTGCGCCGGGCGCTGGAGATCGGCAACGCGGCGCGCATCGACGCCCTGAACACGCGGTTCGAGCATCTGGC
CGCCAGCATCCGCACCGGGGTCATCTACCTCATCGATGCCGACGGCCACACCATCGTGGCGAGCAACTACCGCACCCCCG
AGAGCTTCCTGAACAGCGACTACGGCTTCCGCCCCTATTTCCGCCTCGCCCTCGCGCAGGGCCGGGCCGAGCATTTCGCC
TTCGGCACCGTCAGCCGCCGTCCGGGCCTCTATCTCGCCCAGCGGGTGGAGGCGGACGGCGTGCCCATCGGCGTGCTGGT
GCTGAAGGCCGAGTTCGACGCGCTGGAGGACGAGTGGCGGCGCTTCGCCGAGCCCACCTTCGTCACCGATGCCCGCCACA
TCGTGCTCATCTCCAGCGTGCCCGGCTTCCGCTTCCGCACCACCCGCCCCCTCGACAAGGTGGAGCGTGAGGCCATCCGC
GAAAGCCTCCAGTTCGGTGACTCGCCCCTCGAACTGCTCGACCTCGACCCCACCGCCGCCGATCCGGCGGTGAAGCGGGT
GCGGTTGCCCGGCCAGGCCAAGCGGGAGGATTTCCTCGAATCCTCCCTGCCCGTGCCCACCACCGACTGGACCCTGTCGG
TGCTCGCACCCACCGCCGCCACCACCAACCTCGCTGGCACCGCGGCGCGCACCTCCGCCGCCCTGCTCGGGGTGGTCGCC
ATCGGCTCGGCGGGGCTATGGCGCACCCGCCGTCGCCGCCGCGCCCGCGCCGAGGCGCAGGAGGCGGAAGCCCGGCGCGA
GCTGGAGGCCCGGGTCGCCGACCGCACCACCGAGCTGAGCGCCGCCAACGCCCAGCTGCGCACGGAGATGGAGGAGCGCC
GCCGCTCCCGCCTTGCCATCGATGCCCTGCAAGACGAACTGGTGCAGGCCTCCAAGCTCGCGGTGCTGGGCCAGATCGCG
GCCGGCGTCGCCCATGAGGTGAACCAGCCGGTGGCGGCCATCCGCACCTTCGCCGAGAATTCCCGCGCCTTCCTGGCGCA
AGGCCAGACCGGTCCGGCGGTGGAGAATCTCGCGACCATCGCCGCGCTCACCGAGCGCATCGGCGCCATCACCGGCGAAT
TGCGCGCCTTCGCCCGCAAATCCGCCGCGCGCCTCGAACCGGTGGGGCTGGGCACCGTGGTGGACGGGGCGCTGCTGCTG
CTGCGCTATCGGCTGCTGCAGAACGACATCACCCTGAAGGTCGACCTCGACGTGCCGGAAGTGCAGGTGACGGGCGACCG
CGTCCGGCTGGAGCAGGTGTTCGTCAACCTCATCCAGAATGCCGCGGAAGCCCTCGACACCCGCCGCGACGGCGAGATCC
GCATCGCCTCCGCCACGGGCGCGGACAAGGTGGTGGTCACGGTGGCCGACAACGGCCCCGGACTGCCGCCGGAAGTGCTG
GGGGCGCTGTTCCTGCCCTTCACCACCACCAAGACGCAGGGGCTGGGGCTGGGCCTCGTCATCTCCAAGGACATCATCAC
CGAATCCGGCGGTACGCTGGCCGTGGCCAATGCGGGCGGCGCCGTCTTCACCATCACCTTACCAAGGGCATCCGAGGCAA
CCTCATGA

Upstream 100 bases:

>100_bases
TCTGAGGTCGGGAATCGGGCTCGACTCGGCGTGCGGATGGATGCACTCTCGCCCTCAATCACGTGCGGAAAATCGCACAC
ATCGAGATGAGGAAACGGGA

Downstream 100 bases:

>100_bases
GCGATGTCGCCTTCATCGACGATGACGACCTGCTGCGCGCCGCCAATGTGCAGGCGCTGATGCTGGCCGACCTCACCGTC
ACCGGCTACGGCTCGGCGCT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MDASPSADRPARRRPILVAAGVVAAIALTLLGLDRVADYAARRWALAQVESSAATAAALRVAVLRSEIEKQRSLPLALAQ
DPDVRRALEIGNAARIDALNTRFEHLAASIRTGVIYLIDADGHTIVASNYRTPESFLNSDYGFRPYFRLALAQGRAEHFA
FGTVSRRPGLYLAQRVEADGVPIGVLVLKAEFDALEDEWRRFAEPTFVTDARHIVLISSVPGFRFRTTRPLDKVEREAIR
ESLQFGDSPLELLDLDPTAADPAVKRVRLPGQAKREDFLESSLPVPTTDWTLSVLAPTAATTNLAGTAARTSAALLGVVA
IGSAGLWRTRRRRRARAEAQEAEARRELEARVADRTTELSAANAQLRTEMEERRRSRLAIDALQDELVQASKLAVLGQIA
AGVAHEVNQPVAAIRTFAENSRAFLAQGQTGPAVENLATIAALTERIGAITGELRAFARKSAARLEPVGLGTVVDGALLL
LRYRLLQNDITLKVDLDVPEVQVTGDRVRLEQVFVNLIQNAAEALDTRRDGEIRIASATGADKVVVTVADNGPGLPPEVL
GALFLPFTTTKTQGLGLGLVISKDIITESGGTLAVANAGGAVFTITLPRASEATS

Sequences:

>Translated_615_residues
MDASPSADRPARRRPILVAAGVVAAIALTLLGLDRVADYAARRWALAQVESSAATAAALRVAVLRSEIEKQRSLPLALAQ
DPDVRRALEIGNAARIDALNTRFEHLAASIRTGVIYLIDADGHTIVASNYRTPESFLNSDYGFRPYFRLALAQGRAEHFA
FGTVSRRPGLYLAQRVEADGVPIGVLVLKAEFDALEDEWRRFAEPTFVTDARHIVLISSVPGFRFRTTRPLDKVEREAIR
ESLQFGDSPLELLDLDPTAADPAVKRVRLPGQAKREDFLESSLPVPTTDWTLSVLAPTAATTNLAGTAARTSAALLGVVA
IGSAGLWRTRRRRRARAEAQEAEARRELEARVADRTTELSAANAQLRTEMEERRRSRLAIDALQDELVQASKLAVLGQIA
AGVAHEVNQPVAAIRTFAENSRAFLAQGQTGPAVENLATIAALTERIGAITGELRAFARKSAARLEPVGLGTVVDGALLL
LRYRLLQNDITLKVDLDVPEVQVTGDRVRLEQVFVNLIQNAAEALDTRRDGEIRIASATGADKVVVTVADNGPGLPPEVL
GALFLPFTTTKTQGLGLGLVISKDIITESGGTLAVANAGGAVFTITLPRASEATS
>Mature_615_residues
MDASPSADRPARRRPILVAAGVVAAIALTLLGLDRVADYAARRWALAQVESSAATAAALRVAVLRSEIEKQRSLPLALAQ
DPDVRRALEIGNAARIDALNTRFEHLAASIRTGVIYLIDADGHTIVASNYRTPESFLNSDYGFRPYFRLALAQGRAEHFA
FGTVSRRPGLYLAQRVEADGVPIGVLVLKAEFDALEDEWRRFAEPTFVTDARHIVLISSVPGFRFRTTRPLDKVEREAIR
ESLQFGDSPLELLDLDPTAADPAVKRVRLPGQAKREDFLESSLPVPTTDWTLSVLAPTAATTNLAGTAARTSAALLGVVA
IGSAGLWRTRRRRRARAEAQEAEARRELEARVADRTTELSAANAQLRTEMEERRRSRLAIDALQDELVQASKLAVLGQIA
AGVAHEVNQPVAAIRTFAENSRAFLAQGQTGPAVENLATIAALTERIGAITGELRAFARKSAARLEPVGLGTVVDGALLL
LRYRLLQNDITLKVDLDVPEVQVTGDRVRLEQVFVNLIQNAAEALDTRRDGEIRIASATGADKVVVTVADNGPGLPPEVL
GALFLPFTTTKTQGLGLGLVISKDIITESGGTLAVANAGGAVFTITLPRASEATS

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=32.0754716981132, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=27.6363636363636, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=136, Percent_Identity=31.6176470588235, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=25.7383966244726, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66126; Mature: 66126

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASPSADRPARRRPILVAAGVVAAIALTLLGLDRVADYAARRWALAQVESSAATAAALR
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLRSEIEKQRSLPLALAQDPDVRRALEIGNAARIDALNTRFEHLAASIRTGVIYLIDA
HHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEEEC
DGHTIVASNYRTPESFLNSDYGFRPYFRLALAQGRAEHFAFGTVSRRPGLYLAQRVEADG
CCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHCCCC
VPIGVLVLKAEFDALEDEWRRFAEPTFVTDARHIVLISSVPGFRFRTTRPLDKVEREAIR
CCEEEEEEEEHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHH
ESLQFGDSPLELLDLDPTAADPAVKRVRLPGQAKREDFLESSLPVPTTDWTLSVLAPTAA
HHHHCCCCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCH
TTNLAGTAARTSAALLGVVAIGSAGLWRTRRRRRARAEAQEAEARRELEARVADRTTELS
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANAQLRTEMEERRRSRLAIDALQDELVQASKLAVLGQIAAGVAHEVNQPVAAIRTFAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
SRAFLAQGQTGPAVENLATIAALTERIGAITGELRAFARKSAARLEPVGLGTVVDGALLL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRYRLLQNDITLKVDLDVPEVQVTGDRVRLEQVFVNLIQNAAEALDTRRDGEIRIASATG
HHHHHHCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ADKVVVTVADNGPGLPPEVLGALFLPFTTTKTQGLGLGLVISKDIITESGGTLAVANAGG
CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEEECCC
AVFTITLPRASEATS
EEEEEECCCCCCCCC
>Mature Secondary Structure
MDASPSADRPARRRPILVAAGVVAAIALTLLGLDRVADYAARRWALAQVESSAATAAALR
CCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAVLRSEIEKQRSLPLALAQDPDVRRALEIGNAARIDALNTRFEHLAASIRTGVIYLIDA
HHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCEEEEEEC
DGHTIVASNYRTPESFLNSDYGFRPYFRLALAQGRAEHFAFGTVSRRPGLYLAQRVEADG
CCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHCCCHHHEEEECCCCCCCCHHHHHHCCCC
VPIGVLVLKAEFDALEDEWRRFAEPTFVTDARHIVLISSVPGFRFRTTRPLDKVEREAIR
CCEEEEEEEEHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHH
ESLQFGDSPLELLDLDPTAADPAVKRVRLPGQAKREDFLESSLPVPTTDWTLSVLAPTAA
HHHHCCCCCCEEEECCCCCCCHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCH
TTNLAGTAARTSAALLGVVAIGSAGLWRTRRRRRARAEAQEAEARRELEARVADRTTELS
HCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AANAQLRTEMEERRRSRLAIDALQDELVQASKLAVLGQIAAGVAHEVNQPVAAIRTFAEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
SRAFLAQGQTGPAVENLATIAALTERIGAITGELRAFARKSAARLEPVGLGTVVDGALLL
CCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRYRLLQNDITLKVDLDVPEVQVTGDRVRLEQVFVNLIQNAAEALDTRRDGEIRIASATG
HHHHHHCCCEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
ADKVVVTVADNGPGLPPEVLGALFLPFTTTKTQGLGLGLVISKDIITESGGTLAVANAGG
CCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCEEEEEECCC
AVFTITLPRASEATS
EEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]