Click here to switch to the map view.

The map label for this gene is 154245107

Identifier: 154245107

GI number: 154245107

Start: 1332686

End: 1333384

Strand: Direct

Name: 154245107

Synonym: Xaut_1159

Alternate gene names: NA

Gene position: 1332686-1333384 (Clockwise)

Preceding gene: 154245106

Following gene: 154245108

Centisome position: 25.1

GC content: 69.96

Gene sequence:

>699_bases
ATGCATATTCTCGTCACCCGTCCGGAGCCTGCCGCCTCCCAGACCGCCGAGCGCCTGCGCACCCTCGGCCACGCGGTGAC
GGTGGACCCCATGCTGCGCATCGCCCCCACCGCGCCGACCCTGCCGGAGGGGCCGTTCGATGCGGTGGCCTTCACCTCCA
TCAACGGCGTGAAAGCGTTTGCACAGCATCCGCAGGGGCCGGATTTCTTCCACCTGCCGGCCTTCGCCGTGGGCCCGCGC
ACCTCGAAGGAAGCGCGCGCCATCGGTTTTGCGAACGTCACCGACTGCGACGGCGACGCCTCGGCCCTCGCCGGGCGTAT
CGCGGGGGCGCTGCCGGCCGGGGCAAGGGTGCTGAATCCGGCGGGCGAGGACCGGGCGGCGGATCTTCAGGCGCTGCTGG
CGGCGCCGGGCATCTCGCTGGAACTCGCCATCGTCTATGCCGCCCAGCCGGCCGATGCCCTCTCGGAGGAGGCGCATGCG
GCGCTGGCCAGCGGAACCGTGACGGCAGCTTTGCACTTGTCCCAGCGTACGGTGAAGACCCTGCTCGCATGTGTCGCCGC
CGCCGGTCTTAACGATCGGTTGATCGAAGTGCGCCAACTGTGCCTGTCGGAACAGGTGGCCGAGCCGTTGGTGAAGGCGG
GACTGAAGGTGGAGGTGGCCACGGCGCCCAACGAGGACGCGCTTCTCGCCCTGCTGTGA

Upstream 100 bases:

>100_bases
AAAACCCGGTTCCGGGCGCGGACTAAATTTCTTTGAGCGCCCCCACATTTTGACGACGGTTCTTTTCGAGCCCGGACACG
TTTTTTTTGCAGAGGCCGCC

Downstream 100 bases:

>100_bases
TGGCATGTGACATGACCTCGCGTAGCGGGGCTGTTGCGGTGCGACGCGGGGCGGTTTATCCGGAACCGGTACAGCGGATC
CGAACTCACGATGGAGGCAC

Product: uroporphyrinogen III synthase HEM4

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen III Synthase

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MHILVTRPEPAASQTAERLRTLGHAVTVDPMLRIAPTAPTLPEGPFDAVAFTSINGVKAFAQHPQGPDFFHLPAFAVGPR
TSKEARAIGFANVTDCDGDASALAGRIAGALPAGARVLNPAGEDRAADLQALLAAPGISLELAIVYAAQPADALSEEAHA
ALASGTVTAALHLSQRTVKTLLACVAAAGLNDRLIEVRQLCLSEQVAEPLVKAGLKVEVATAPNEDALLALL

Sequences:

>Translated_232_residues
MHILVTRPEPAASQTAERLRTLGHAVTVDPMLRIAPTAPTLPEGPFDAVAFTSINGVKAFAQHPQGPDFFHLPAFAVGPR
TSKEARAIGFANVTDCDGDASALAGRIAGALPAGARVLNPAGEDRAADLQALLAAPGISLELAIVYAAQPADALSEEAHA
ALASGTVTAALHLSQRTVKTLLACVAAAGLNDRLIEVRQLCLSEQVAEPLVKAGLKVEVATAPNEDALLALL
>Mature_232_residues
MHILVTRPEPAASQTAERLRTLGHAVTVDPMLRIAPTAPTLPEGPFDAVAFTSINGVKAFAQHPQGPDFFHLPAFAVGPR
TSKEARAIGFANVTDCDGDASALAGRIAGALPAGARVLNPAGEDRAADLQALLAAPGISLELAIVYAAQPADALSEEAHA
ALASGTVTAALHLSQRTVKTLLACVAAAGLNDRLIEVRQLCLSEQVAEPLVKAGLKVEVATAPNEDALLALL

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 23836; Mature: 23836

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHILVTRPEPAASQTAERLRTLGHAVTVDPMLRIAPTAPTLPEGPFDAVAFTSINGVKAF
CEEEEECCCCCHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCCCCEEEEECCCHHHHH
AQHPQGPDFFHLPAFAVGPRTSKEARAIGFANVTDCDGDASALAGRIAGALPAGARVLNP
HCCCCCCCEEECCCEEECCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECC
AGEDRAADLQALLAAPGISLELAIVYAAQPADALSEEAHAALASGTVTAALHLSQRTVKT
CCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
LLACVAAAGLNDRLIEVRQLCLSEQVAEPLVKAGLKVEVATAPNEDALLALL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEC
>Mature Secondary Structure
MHILVTRPEPAASQTAERLRTLGHAVTVDPMLRIAPTAPTLPEGPFDAVAFTSINGVKAF
CEEEEECCCCCHHHHHHHHHHHCCEEEECCCEEECCCCCCCCCCCCCEEEEECCCHHHHH
AQHPQGPDFFHLPAFAVGPRTSKEARAIGFANVTDCDGDASALAGRIAGALPAGARVLNP
HCCCCCCCEEECCCEEECCCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCCCCEEECC
AGEDRAADLQALLAAPGISLELAIVYAAQPADALSEEAHAALASGTVTAALHLSQRTVKT
CCCCHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHH
LLACVAAAGLNDRLIEVRQLCLSEQVAEPLVKAGLKVEVATAPNEDALLALL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA