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The map label for this gene is tas [H]

Identifier: 154245073

GI number: 154245073

Start: 1294344

End: 1295399

Strand: Reverse

Name: tas [H]

Synonym: Xaut_1125

Alternate gene names: 154245073

Gene position: 1295399-1294344 (Counterclockwise)

Preceding gene: 154245079

Following gene: 154245070

Centisome position: 24.4

GC content: 68.66

Gene sequence:

>1056_bases
ATGCTCGATTATCGCCCCCTCGGGCGCACCGGCCTTTCGGTGTCGTCCATCTCGCTTGGCACCATGACCTTCGGCCAGCA
GAACACCGAAGCCGAGGGCCACGCCCAGCTCGACCGCGCCCGCGACGTGGGCATCAACCTGATCGACACCGCGGAGATGT
ATTCCATCCCGCCCCGGCCGGAGACCCAGGGCTCCACGGAACGCATCATCGGCACCTGGCTGAAGTCCCGCGGCGGGCGC
GACAAGGTGGTCCTCGCCACCAAGGTGTCCGGCCGCACCGACAACACCTGGCTGCGCGAGAACGGCGCCAAGACCCGGCT
CGATGCCAAGAACATCACCTATGCCATCGAGGGGTCCCTGAAGCGGCTGCAGACCGATTACGTGGACCTCTACCAGCTGC
ACTGGCCCGACCGCGCCGTGCCCCTGTTCGGCAACCCGGCCTCGGCCATCACAAGCAGCACGGGCGATGGTCCGGAAGTG
CCCATCGAGGAGACGCTGGGGGCGCTCGCTGATCTGGTAAGCGCGGGCAAGGTGCGTCACATCGGTCTGTCCAACGAAAC
GCCCTGGGGCCTCCACCGCTTCCTCAAGGCGGCGGACACCGGCGGCGGGCCGCGCGTCGCCTCGGTGCAGAACGCGTACC
ATCTCCTCAACCGCGAGTATGAGGTGGGCCTCGCAGAGTTCGCCGCACGGGAGGATGTGGGCCTGCTCGCCTATTCGCCC
CTGGCGCAGGGCTATCTCACCGGCAAGTATCTGGACGGCGCGCGCCCGGCCGGCGCACGCTCCACCCTGTTCGATCGCGG
CCAGCGCTACCAGAAGCCCGGCGTGGACCCGGCCATCAAGGCCTATCTGGCGCTGGCGGCGGACCTTGGCCTGACGGCGG
TGCAACTGGCGCAGGCGTGGGTGACGAGCCGGCCGTTCGTGACCTCCAACATCATCGGCGCTACGTCCATGGCGCAGCTG
GAGGAGACGCTCGCCACCCTCGACGTGGTCATCACCCCGGAGATCGAGGCCCGGGTGAACGCCGTGTTCCAGCTCCACGG
CAGCCCGGCCCCCTGA

Upstream 100 bases:

>100_bases
CCGCTGGGCTGTCCTTACCTCTCCTCCCGTTGACGGACGCCCGCCTCAGGGTCTTTTCTGCCCTCCCCTCCCTTGCCCGT
CCCCCGGAGCATTGCCCTTC

Downstream 100 bases:

>100_bases
GGGGCGGGGTAGTCGCGCGAGGCGCTTCCGGCGCGGGACCCATGGTCACCGCGCCGGCTCTCAGAACCTCAGTTGGTCCG
GCGCCAGGTTTCGCCGCTGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MLDYRPLGRTGLSVSSISLGTMTFGQQNTEAEGHAQLDRARDVGINLIDTAEMYSIPPRPETQGSTERIIGTWLKSRGGR
DKVVLATKVSGRTDNTWLRENGAKTRLDAKNITYAIEGSLKRLQTDYVDLYQLHWPDRAVPLFGNPASAITSSTGDGPEV
PIEETLGALADLVSAGKVRHIGLSNETPWGLHRFLKAADTGGGPRVASVQNAYHLLNREYEVGLAEFAAREDVGLLAYSP
LAQGYLTGKYLDGARPAGARSTLFDRGQRYQKPGVDPAIKAYLALAADLGLTAVQLAQAWVTSRPFVTSNIIGATSMAQL
EETLATLDVVITPEIEARVNAVFQLHGSPAP

Sequences:

>Translated_351_residues
MLDYRPLGRTGLSVSSISLGTMTFGQQNTEAEGHAQLDRARDVGINLIDTAEMYSIPPRPETQGSTERIIGTWLKSRGGR
DKVVLATKVSGRTDNTWLRENGAKTRLDAKNITYAIEGSLKRLQTDYVDLYQLHWPDRAVPLFGNPASAITSSTGDGPEV
PIEETLGALADLVSAGKVRHIGLSNETPWGLHRFLKAADTGGGPRVASVQNAYHLLNREYEVGLAEFAAREDVGLLAYSP
LAQGYLTGKYLDGARPAGARSTLFDRGQRYQKPGVDPAIKAYLALAADLGLTAVQLAQAWVTSRPFVTSNIIGATSMAQL
EETLATLDVVITPEIEARVNAVFQLHGSPAP
>Mature_351_residues
MLDYRPLGRTGLSVSSISLGTMTFGQQNTEAEGHAQLDRARDVGINLIDTAEMYSIPPRPETQGSTERIIGTWLKSRGGR
DKVVLATKVSGRTDNTWLRENGAKTRLDAKNITYAIEGSLKRLQTDYVDLYQLHWPDRAVPLFGNPASAITSSTGDGPEV
PIEETLGALADLVSAGKVRHIGLSNETPWGLHRFLKAADTGGGPRVASVQNAYHLLNREYEVGLAEFAAREDVGLLAYSP
LAQGYLTGKYLDGARPAGARSTLFDRGQRYQKPGVDPAIKAYLALAADLGLTAVQLAQAWVTSRPFVTSNIIGATSMAQL
EETLATLDVVITPEIEARVNAVFQLHGSPAP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=342, Percent_Identity=30.9941520467836, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI4504825, Length=342, Percent_Identity=30.9941520467836, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI27436971, Length=357, Percent_Identity=31.0924369747899, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI27436964, Length=356, Percent_Identity=29.7752808988764, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI27436962, Length=356, Percent_Identity=30.3370786516854, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI27436966, Length=356, Percent_Identity=29.4943820224719, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI223718702, Length=354, Percent_Identity=28.2485875706215, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI41327764, Length=358, Percent_Identity=29.8882681564246, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI41152114, Length=328, Percent_Identity=28.3536585365854, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=49.7159090909091, Blast_Score=335, Evalue=2e-93,
Organism=Escherichia coli, GI87081735, Length=359, Percent_Identity=33.7047353760446, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1789375, Length=340, Percent_Identity=29.7058823529412, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788070, Length=339, Percent_Identity=29.4985250737463, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788081, Length=341, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=352, Percent_Identity=29.2613636363636, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=345, Percent_Identity=26.3768115942029, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=316, Percent_Identity=25.3164556962025, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319951, Length=304, Percent_Identity=23.6842105263158, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=271, Percent_Identity=24.7232472324723, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24646155, Length=250, Percent_Identity=30.4, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646159, Length=225, Percent_Identity=32.8888888888889, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 37825; Mature: 37825

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDYRPLGRTGLSVSSISLGTMTFGQQNTEAEGHAQLDRARDVGINLIDTAEMYSIPPRP
CCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECHHHHCCCCCC
ETQGSTERIIGTWLKSRGGRDKVVLATKVSGRTDNTWLRENGAKTRLDAKNITYAIEGSL
CCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHCCCCCCEECCCCEEEEECCHH
KRLQTDYVDLYQLHWPDRAVPLFGNPASAITSSTGDGPEVPIEETLGALADLVSAGKVRH
HHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
IGLSNETPWGLHRFLKAADTGGGPRVASVQNAYHLLNREYEVGLAEFAAREDVGLLAYSP
ECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCHHHHHHHCCCCEEEECH
LAQGYLTGKYLDGARPAGARSTLFDRGQRYQKPGVDPAIKAYLALAADLGLTAVQLAQAW
HHCCCEECEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
VTSRPFVTSNIIGATSMAQLEETLATLDVVITPEIEARVNAVFQLHGSPAP
HCCCCCHHHCCCCHHHHHHHHHHHHHEEEEECCCHHHHEEEEEEECCCCCC
>Mature Secondary Structure
MLDYRPLGRTGLSVSSISLGTMTFGQQNTEAEGHAQLDRARDVGINLIDTAEMYSIPPRP
CCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEECHHHHCCCCCC
ETQGSTERIIGTWLKSRGGRDKVVLATKVSGRTDNTWLRENGAKTRLDAKNITYAIEGSL
CCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHHCCCCCCEECCCCEEEEECCHH
KRLQTDYVDLYQLHWPDRAVPLFGNPASAITSSTGDGPEVPIEETLGALADLVSAGKVRH
HHHHHHHHHEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEEE
IGLSNETPWGLHRFLKAADTGGGPRVASVQNAYHLLNREYEVGLAEFAAREDVGLLAYSP
ECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHCCHHHHHHHCCCCEEEECH
LAQGYLTGKYLDGARPAGARSTLFDRGQRYQKPGVDPAIKAYLALAADLGLTAVQLAQAW
HHCCCEECEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
VTSRPFVTSNIIGATSMAQLEETLATLDVVITPEIEARVNAVFQLHGSPAP
HCCCCCHHHCCCCHHHHHHHHHHHHHEEEEECCCHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]