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The map label for this gene is rsmB [H]

Identifier: 154244891

GI number: 154244891

Start: 1061143

End: 1062579

Strand: Direct

Name: rsmB [H]

Synonym: Xaut_0941

Alternate gene names: 154244891

Gene position: 1061143-1062579 (Clockwise)

Preceding gene: 154244890

Following gene: 154244896

Centisome position: 19.99

GC content: 66.74

Gene sequence:

>1437_bases
ATGGTGCCGCCGTTTTCCAGCCTGATCGTCTCTCCTGTGACTCCCGCCGCCCGTCTGCAAGCTACTCTCGAACTGATGCA
TGAAGTCGACAGTGTCGCGCGCCCCGCCGATGCTGTCGTCTCGGCGTGGTTTCGAGCCCGACGCCAAATCGGAGACAGGG
ATCGCGGCCAGATCTACGATCTGCTCTATGCGCTACTGCGGCATCACGCGCGAATAGTCTGGTGGTTGGCAAAGCACGGG
CGTCCGGACGTGCCGCGCAACCGGCTTTTGGCATGGCTTGCGCTCGATGGGGGCACGGCCTTGGGGGGCAAGACCTCGGG
GAATAAGACCTCGGGGAATAAGACCTCGGGGAATAAGACCTCGGGGAATAAGACCTCCGGAAGCAAGACGCCGGACCAGA
TCCATGGCTTGTTCAGCGGTGGAAAATTCGCGCCTGCCGTTTTGACCGATCATGAGCGCGCGCTGCTGCTCAAACTGCAG
GGGTGCACGATCGACCACCCGGCCATGCCGGACGAGGTGCGCTTTGAATGTCCGTCCTGGGCGGTCGAGCCCTTGCGGCG
GCGTTTCGATGACACGTTCGAGCGCGAGATGGCCGCGCTTCTGACGCCGCCTCCACTCGATCTGCGCGTCAATCCGGTCA
AGTCCACGCGCGAGGCGATGCTGCGCGCGCTGCGCGATCTTGGCCTGAAGGCCGAGCCGTCCCGCCTGGCGCCTTTTGGC
ATCCGCGTGAAGGAGCGCCCCTCGCTGGCCAGCCTGCCCATGCTGAAGAGCGGCGAGGTGGAGATCCAGGATGAGGGCTC
GCAGCTCGTTGCCATGCTGGTCGATGCGCGGCCGGGCGAACGGGTGGTGGATTTCTGTGCCGGGGCCGGCGGCAAGACGC
TGGCCATTGCCGCGCAGATGGCGAACAAGGGCCACGTGATTGCCTGCGATGTCTCGGATGGCCGCCTGAAGCGCGCCGCC
GAGCGGTTCCGGCGCGCGGGCCTCCACAACATCGAGACCCGGCCCCTGGCCAGCGAAACCGATCGCTGGGTGAAGCGCCA
CAAGGGCGGCTTCGATCGCGTGCTGGTCGATGCGCCATGCAGCGGCACCGGCACGTGGCGGCGCAATCCCGATGCCCGCT
GGCGGCAGCAGGAGGCGGGGCTCGATCATCTCCTGCCGCTGCAGGCCCGTATTCTTGCCAGCGCCGCTCGGCTGGTGAAG
CCCGGCGGGCGGCTCGTCTACGCCACATGCTCCATGCTGCCGGAGGAGAACGAGGCCCAGGTGGCGGCATTCCTTGCGGC
CTATCCCGCCTTTCATGTCATGCCGGTGCGCGAGGCTGCGCCACAACTGACCGGTTCTGCGCATCCGGATCACCTGTCGC
TAACGCCGGCGCGCCACGAGACGGACGGGTTTTTTGCCGCCGTCCTGCAGCGCGAGCCCGCGGCAGCGCCCGCGTAA

Upstream 100 bases:

>100_bases
TCGGGGCCGGTCGCGCGGACGCTGGGGGCTCCTCATGTTGCCCCCACAGGCACAGTCTGGGAGACGTGCGAATCCATAGT
CAGCGGCAGCGCCTTCATCT

Downstream 100 bases:

>100_bases
AAATCGTCGCCGGGCAATGCGGGAAACCCCGCCTGCCCACCGGACCTTTACTTGCGGATGGGAACGCCCTTGGTGGTGAA
GCGCTGCGTCCCGGCGGTGC

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MVPPFSSLIVSPVTPAARLQATLELMHEVDSVARPADAVVSAWFRARRQIGDRDRGQIYDLLYALLRHHARIVWWLAKHG
RPDVPRNRLLAWLALDGGTALGGKTSGNKTSGNKTSGNKTSGNKTSGSKTPDQIHGLFSGGKFAPAVLTDHERALLLKLQ
GCTIDHPAMPDEVRFECPSWAVEPLRRRFDDTFEREMAALLTPPPLDLRVNPVKSTREAMLRALRDLGLKAEPSRLAPFG
IRVKERPSLASLPMLKSGEVEIQDEGSQLVAMLVDARPGERVVDFCAGAGGKTLAIAAQMANKGHVIACDVSDGRLKRAA
ERFRRAGLHNIETRPLASETDRWVKRHKGGFDRVLVDAPCSGTGTWRRNPDARWRQQEAGLDHLLPLQARILASAARLVK
PGGRLVYATCSMLPEENEAQVAAFLAAYPAFHVMPVREAAPQLTGSAHPDHLSLTPARHETDGFFAAVLQREPAAAPA

Sequences:

>Translated_478_residues
MVPPFSSLIVSPVTPAARLQATLELMHEVDSVARPADAVVSAWFRARRQIGDRDRGQIYDLLYALLRHHARIVWWLAKHG
RPDVPRNRLLAWLALDGGTALGGKTSGNKTSGNKTSGNKTSGNKTSGSKTPDQIHGLFSGGKFAPAVLTDHERALLLKLQ
GCTIDHPAMPDEVRFECPSWAVEPLRRRFDDTFEREMAALLTPPPLDLRVNPVKSTREAMLRALRDLGLKAEPSRLAPFG
IRVKERPSLASLPMLKSGEVEIQDEGSQLVAMLVDARPGERVVDFCAGAGGKTLAIAAQMANKGHVIACDVSDGRLKRAA
ERFRRAGLHNIETRPLASETDRWVKRHKGGFDRVLVDAPCSGTGTWRRNPDARWRQQEAGLDHLLPLQARILASAARLVK
PGGRLVYATCSMLPEENEAQVAAFLAAYPAFHVMPVREAAPQLTGSAHPDHLSLTPARHETDGFFAAVLQREPAAAPA
>Mature_478_residues
MVPPFSSLIVSPVTPAARLQATLELMHEVDSVARPADAVVSAWFRARRQIGDRDRGQIYDLLYALLRHHARIVWWLAKHG
RPDVPRNRLLAWLALDGGTALGGKTSGNKTSGNKTSGNKTSGNKTSGSKTPDQIHGLFSGGKFAPAVLTDHERALLLKLQ
GCTIDHPAMPDEVRFECPSWAVEPLRRRFDDTFEREMAALLTPPPLDLRVNPVKSTREAMLRALRDLGLKAEPSRLAPFG
IRVKERPSLASLPMLKSGEVEIQDEGSQLVAMLVDARPGERVVDFCAGAGGKTLAIAAQMANKGHVIACDVSDGRLKRAA
ERFRRAGLHNIETRPLASETDRWVKRHKGGFDRVLVDAPCSGTGTWRRNPDARWRQQEAGLDHLLPLQARILASAARLVK
PGGRLVYATCSMLPEENEAQVAAFLAAYPAFHVMPVREAAPQLTGSAHPDHLSLTPARHETDGFFAAVLQREPAAAPA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=301, Percent_Identity=30.8970099667774, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI76150623, Length=301, Percent_Identity=30.8970099667774, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI32698918, Length=196, Percent_Identity=35.2040816326531, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI23199998, Length=265, Percent_Identity=34.7169811320755, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI270288818, Length=267, Percent_Identity=34.4569288389513, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI270288816, Length=267, Percent_Identity=34.4569288389513, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI8922322, Length=267, Percent_Identity=34.4569288389513, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI39995082, Length=185, Percent_Identity=32.4324324324324, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI301336155, Length=185, Percent_Identity=32.4324324324324, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI11545785, Length=188, Percent_Identity=31.9148936170213, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI40316918, Length=172, Percent_Identity=31.9767441860465, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI2367212, Length=429, Percent_Identity=28.6713286713287, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI87081985, Length=296, Percent_Identity=30.0675675675676, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17536757, Length=287, Percent_Identity=31.0104529616725, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25143471, Length=206, Percent_Identity=35.4368932038835, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17509941, Length=195, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324268, Length=282, Percent_Identity=29.4326241134752, Blast_Score=113, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6319447, Length=186, Percent_Identity=31.1827956989247, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI22024126, Length=282, Percent_Identity=31.2056737588652, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21355201, Length=178, Percent_Identity=35.3932584269663, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668781, Length=258, Percent_Identity=29.4573643410853, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI21356513, Length=258, Percent_Identity=29.4573643410853, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI19920494, Length=166, Percent_Identity=32.5301204819277, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21356579, Length=227, Percent_Identity=26.8722466960352, Blast_Score=82, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 52195; Mature: 52195

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPPFSSLIVSPVTPAARLQATLELMHEVDSVARPADAVVSAWFRARRQIGDRDRGQIYD
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
LLYALLRHHARIVWWLAKHGRPDVPRNRLLAWLALDGGTALGGKTSGNKTSGNKTSGNKT
HHHHHHHHHHHEEEEEECCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
SGNKTSGSKTPDQIHGLFSGGKFAPAVLTDHERALLLKLQGCTIDHPAMPDEVRFECPSW
CCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCEECCCCH
AVEPLRRRFDDTFEREMAALLTPPPLDLRVNPVKSTREAMLRALRDLGLKAEPSRLAPFG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
IRVKERPSLASLPMLKSGEVEIQDEGSQLVAMLVDARPGERVVDFCAGAGGKTLAIAAQM
EEECCCCCHHCCCCCCCCCEEEECCCCEEEEHEECCCCCHHHHHHHCCCCCCEEEEEEEC
ANKGHVIACDVSDGRLKRAAERFRRAGLHNIETRPLASETDRWVKRHKGGFDRVLVDAPC
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
SGTGTWRRNPDARWRQQEAGLDHLLPLQARILASAARLVKPGGRLVYATCSMLPEENEAQ
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCHHH
VAAFLAAYPAFHVMPVREAAPQLTGSAHPDHLSLTPARHETDGFFAAVLQREPAAAPA
HHHHHHHCCHHEEEEHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVPPFSSLIVSPVTPAARLQATLELMHEVDSVARPADAVVSAWFRARRQIGDRDRGQIYD
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHH
LLYALLRHHARIVWWLAKHGRPDVPRNRLLAWLALDGGTALGGKTSGNKTSGNKTSGNKT
HHHHHHHHHHHEEEEEECCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCC
SGNKTSGSKTPDQIHGLFSGGKFAPAVLTDHERALLLKLQGCTIDHPAMPDEVRFECPSW
CCCCCCCCCCHHHHHHHHCCCCCCCCEECCCCCEEEEEEECCCCCCCCCCCCCEECCCCH
AVEPLRRRFDDTFEREMAALLTPPPLDLRVNPVKSTREAMLRALRDLGLKAEPSRLAPFG
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
IRVKERPSLASLPMLKSGEVEIQDEGSQLVAMLVDARPGERVVDFCAGAGGKTLAIAAQM
EEECCCCCHHCCCCCCCCCEEEECCCCEEEEHEECCCCCHHHHHHHCCCCCCEEEEEEEC
ANKGHVIACDVSDGRLKRAAERFRRAGLHNIETRPLASETDRWVKRHKGGFDRVLVDAPC
CCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCC
SGTGTWRRNPDARWRQQEAGLDHLLPLQARILASAARLVKPGGRLVYATCSMLPEENEAQ
CCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCHHH
VAAFLAAYPAFHVMPVREAAPQLTGSAHPDHLSLTPARHETDGFFAAVLQREPAAAPA
HHHHHHHCCHHEEEEHHHHCCCCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]