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The map label for this gene is ycgM [C]

Identifier: 154244890

GI number: 154244890

Start: 1060097

End: 1060945

Strand: Direct

Name: ycgM [C]

Synonym: Xaut_0940

Alternate gene names: 154244890

Gene position: 1060097-1060945 (Clockwise)

Preceding gene: 154244889

Following gene: 154244891

Centisome position: 19.97

GC content: 66.08

Gene sequence:

>849_bases
ATGAAGCTCTTGCGATTTGGACCCGCCGGCACCGAAAAGCCGGGCGCCCTCGATGATGCCGGCCGCATCCGCGACCTCTC
CGGCGTGATCGCGGACCTCTCGGGGGATGTGCTTTCGCCGGGCAGCATTGCGCGCCTGTCCGCCCTCGATCTGTCCACGC
TGCCGGTGGTGGAGGGCGAACCGCGCCTGGGGTGCCCGGTGGGGAACGTCGGCAAGTTCATCGCCGTCGGCCTGAACTAT
GCAGACCATGCCGCCGAGGCCAACATGGCTCTTCCCAGCGAGCCCGTCATCTTCTCCAAGGCCACGAGCTGCATCGTCGG
CCCCAACGACGACGTGGTCCTTCCGCCGGCGTCCGCCAAGGGCGACTGGGAAGTCGAATTGGGCATCGTCATCGGACAGA
CCACACGCTACGTCACGCCCGACGCGGCGCTGGGCCATGTGGCGGGATATTGCCTGGTGAACGACGTGTCCGAACGCGAA
TACCAGCTGGAGCGCGGCGGCACGTGGGACAAGGGCAAGGGCTTCGACACCTTCGGGCCGATCGGGCCTTATGTCGTCAC
TGCCGATGAGGTTCAGGATCCGCAGGCGCTGGACCTGTGGCTCGACGTCAACGGACGGCGCATGCAGAGCGGCAACACCC
GCACCATGATCTTCGATGTCGCGACGCTGGTGAGCTACATCAGCCGCATCATGACCCTGTTTCCGGGCGATGTGATTACG
ACCGGCACGCCGCCGGGCGTGGGCATGGGGCAGAAGCCGGGGCCGATCTACCTGAAGGCCGGCGACGTGATGGAACTGGG
CATCGAAAAGCTCGGAACCCAGAGGCAACGGGTGCGGGCCTGGGCTTGA

Upstream 100 bases:

>100_bases
TTCGCCCCGCCCTTGCCTGATCCACGCCTCGCCCCCCGGCGCTGCCGGGGGGCCGCAAGCGCGGGCGGGATGATCGAAAC
CTCCAGGGAAGGAACATGAA

Downstream 100 bases:

>100_bases
TGCCTGTTTGAGGCTTGAAGAAGAAAATACACAGGACGGGGCAACACGTGCCATTCCGGTCCTCGGCCCTGGCGCCGCGC
TCGCCATCGCTGGAAGCTCG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKLLRFGPAGTEKPGALDDAGRIRDLSGVIADLSGDVLSPGSIARLSALDLSTLPVVEGEPRLGCPVGNVGKFIAVGLNY
ADHAAEANMALPSEPVIFSKATSCIVGPNDDVVLPPASAKGDWEVELGIVIGQTTRYVTPDAALGHVAGYCLVNDVSERE
YQLERGGTWDKGKGFDTFGPIGPYVVTADEVQDPQALDLWLDVNGRRMQSGNTRTMIFDVATLVSYISRIMTLFPGDVIT
TGTPPGVGMGQKPGPIYLKAGDVMELGIEKLGTQRQRVRAWA

Sequences:

>Translated_282_residues
MKLLRFGPAGTEKPGALDDAGRIRDLSGVIADLSGDVLSPGSIARLSALDLSTLPVVEGEPRLGCPVGNVGKFIAVGLNY
ADHAAEANMALPSEPVIFSKATSCIVGPNDDVVLPPASAKGDWEVELGIVIGQTTRYVTPDAALGHVAGYCLVNDVSERE
YQLERGGTWDKGKGFDTFGPIGPYVVTADEVQDPQALDLWLDVNGRRMQSGNTRTMIFDVATLVSYISRIMTLFPGDVIT
TGTPPGVGMGQKPGPIYLKAGDVMELGIEKLGTQRQRVRAWA
>Mature_282_residues
MKLLRFGPAGTEKPGALDDAGRIRDLSGVIADLSGDVLSPGSIARLSALDLSTLPVVEGEPRLGCPVGNVGKFIAVGLNY
ADHAAEANMALPSEPVIFSKATSCIVGPNDDVVLPPASAKGDWEVELGIVIGQTTRYVTPDAALGHVAGYCLVNDVSERE
YQLERGGTWDKGKGFDTFGPIGPYVVTADEVQDPQALDLWLDVNGRRMQSGNTRTMIFDVATLVSYISRIMTLFPGDVIT
TGTPPGVGMGQKPGPIYLKAGDVMELGIEKLGTQRQRVRAWA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=239, Percent_Identity=47.6987447698745, Blast_Score=223, Evalue=1e-58,
Organism=Homo sapiens, GI40786394, Length=239, Percent_Identity=46.8619246861925, Blast_Score=215, Evalue=4e-56,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=38.6138613861386, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI13654274, Length=210, Percent_Identity=37.6190476190476, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI215422413, Length=202, Percent_Identity=38.6138613861386, Blast_Score=136, Evalue=2e-32,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=37.3626373626374, Blast_Score=124, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17557057, Length=207, Percent_Identity=34.2995169082126, Blast_Score=130, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324161, Length=218, Percent_Identity=32.1100917431193, Blast_Score=97, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28572127, Length=232, Percent_Identity=43.5344827586207, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI24663695, Length=238, Percent_Identity=35.2941176470588, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI28571789, Length=229, Percent_Identity=37.117903930131, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29880; Mature: 29880

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRFGPAGTEKPGALDDAGRIRDLSGVIADLSGDVLSPGSIARLSALDLSTLPVVEGE
CCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEECCC
PRLGCPVGNVGKFIAVGLNYADHAAEANMALPSEPVIFSKATSCIVGPNDDVVLPPASAK
CCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCC
GDWEVELGIVIGQTTRYVTPDAALGHVAGYCLVNDVSEREYQLERGGTWDKGKGFDTFGP
CCEEEEEEEEEECCEEEECCCHHHHHHHHEEEEECCCHHHEEHHCCCCCCCCCCCCCCCC
IGPYVVTADEVQDPQALDLWLDVNGRRMQSGNTRTMIFDVATLVSYISRIMTLFPGDVIT
CCCEEEECCCCCCCCEEEEEEECCCCEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEE
TGTPPGVGMGQKPGPIYLKAGDVMELGIEKLGTQRQRVRAWA
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MKLLRFGPAGTEKPGALDDAGRIRDLSGVIADLSGDVLSPGSIARLSALDLSTLPVVEGE
CCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCEECCC
PRLGCPVGNVGKFIAVGLNYADHAAEANMALPSEPVIFSKATSCIVGPNDDVVLPPASAK
CCCCCCCCCCCCEEEEECCCHHHHCCCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCC
GDWEVELGIVIGQTTRYVTPDAALGHVAGYCLVNDVSEREYQLERGGTWDKGKGFDTFGP
CCEEEEEEEEEECCEEEECCCHHHHHHHHEEEEECCCHHHEEHHCCCCCCCCCCCCCCCC
IGPYVVTADEVQDPQALDLWLDVNGRRMQSGNTRTMIFDVATLVSYISRIMTLFPGDVIT
CCCEEEECCCCCCCCEEEEEEECCCCEECCCCCEEEEHHHHHHHHHHHHHHHHCCCCEEE
TGTPPGVGMGQKPGPIYLKAGDVMELGIEKLGTQRQRVRAWA
CCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA