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The map label for this gene is sdaA [H]

Identifier: 154244821

GI number: 154244821

Start: 971246

End: 972592

Strand: Reverse

Name: sdaA [H]

Synonym: Xaut_0871

Alternate gene names: 154244821

Gene position: 972592-971246 (Counterclockwise)

Preceding gene: 154244830

Following gene: 154244820

Centisome position: 18.32

GC content: 69.86

Gene sequence:

>1347_bases
ATGATCAGCGTGTTCGACCTCTTCAAGATCGGCATCGGGCCGTCCTCGTCGCACACGGTGGGGCCCATGGTGGCGGCGCG
GCGGTTTCGCGAGGGGCTGCCGCAGGGCACCCGGCGCGTCACGGCGGAACTGTTCGGCTCGCTGGCCTGGACCGGCAAGG
GCCATGGCTCCGACACCGCCATCTGGCTCGGCCTCATGGGCGCCGCGCCCGATACGCTCGACCCGGACGAGGTGCCGGTG
CTCACCGCGCGCCTCGCCATCCAGAAATTCATCGAGGCCGGCGGCGCGCGCATCGCCTTCGATACCGAGCGCGACCTGAT
CTTCGATTTCGCCACCCTGCTGCCGCTCCACTCCAACGGCATGCGCTTCCGCGCATTTGGAGAAGACGGCGCGACCCTCG
AAGAACGTGTGTTCTATTCCATCGGCGGTGGCTTCGTGGTGGAGGAGGGTGAGACCCGCGAGGCGCCGGCGCAGGACGTG
CCCCACCCTTTCGCCACGGCGGCGGAGCTGCTCTCCGCCTGCGCCCGCGCGCAACTCTCCATCGCCGATCTGCAGATGGC
CAACGAATGCGCCCTGCGCCCGCGCGAAGACGTGGAGCGGGGGCTGGATGCCATTCTGGACGCCATGTTCGCCTCCATCG
ACCGGGGCCTTGCCCGCGAGGGCGCCCTGCCCGGCCGGCTCCGGGTGAAGCGGCGCGCCAGGGCAATCCACGACCAACTG
CAGGCCGATCGGCTCACCAACCAGCGTCCGCCCCATGAGGTCATGGACTGGGTCTCGGTGTTCGCCATGGCGGTGAACGA
GGAGAATGCCGCCGGCGGGCGCATCGTCACCGCCCCCACCAATGGGGCGGCGGGCATCGTGCCGGCGGTGCTGCGCTATG
TGCGCGACATCTGCCCCGACACGAGCCACGCCCAGTTGCGGGACTTCCTTTTGACCGCAGCGGCGGTGGGCGCGCTCATC
AAGCGCAACGCCTCCATCTCCGGCGCCGAGGTGGGCTGCCAGGGCGAGGTGGGCTCGGCCGCCTCCATGGCGGCGGCGGG
ACTCGCGGCAGTGCTGGGGGCAAGCCCGGCGCAGATCGAGAACGCCGCCGAGATCGCCATGGAACATCACCTCGGCATGA
CCTGCGACCCCATCGGCGGGCTGGTGCAGATCCCGTGCATCGAGCGCAACGCCTTCGGCGCCAACAAGGCCATCGCGGCG
GCCTCGCTGGCGCTGCGCGGCGACGGCATCCACCACGTCTCCCTGGACCAGGTGATCGAGACCATGCGCCAGACCGGCGC
CGACATGCAGTCCAAATACAAGGAAACCTCGCAGGGCGGCCTCGCGGTCAACGTGCCGGAATGCTGA

Upstream 100 bases:

>100_bases
CACTCCGGCGCCGCGTGAAAAGCACCGCTTCCCCCACCCGTCCTGTCCCGCGAGCGGGAGAGGGTTCCAGCGCGCCCCAC
CTTCAAACCAGAGGCAACGG

Downstream 100 bases:

>100_bases
GCCGCCCCGCCCATCCCCATCCCTTCCAGAAGGACCAACGCCCATGACCCTTCACGTTGCCCCGACCCACGCCGCCGACC
CCGCCGTGTTCGACGCCATC

Product: L-serine dehydratase 1

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MISVFDLFKIGIGPSSSHTVGPMVAARRFREGLPQGTRRVTAELFGSLAWTGKGHGSDTAIWLGLMGAAPDTLDPDEVPV
LTARLAIQKFIEAGGARIAFDTERDLIFDFATLLPLHSNGMRFRAFGEDGATLEERVFYSIGGGFVVEEGETREAPAQDV
PHPFATAAELLSACARAQLSIADLQMANECALRPREDVERGLDAILDAMFASIDRGLAREGALPGRLRVKRRARAIHDQL
QADRLTNQRPPHEVMDWVSVFAMAVNEENAAGGRIVTAPTNGAAGIVPAVLRYVRDICPDTSHAQLRDFLLTAAAVGALI
KRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPAQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAA
ASLALRGDGIHHVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC

Sequences:

>Translated_448_residues
MISVFDLFKIGIGPSSSHTVGPMVAARRFREGLPQGTRRVTAELFGSLAWTGKGHGSDTAIWLGLMGAAPDTLDPDEVPV
LTARLAIQKFIEAGGARIAFDTERDLIFDFATLLPLHSNGMRFRAFGEDGATLEERVFYSIGGGFVVEEGETREAPAQDV
PHPFATAAELLSACARAQLSIADLQMANECALRPREDVERGLDAILDAMFASIDRGLAREGALPGRLRVKRRARAIHDQL
QADRLTNQRPPHEVMDWVSVFAMAVNEENAAGGRIVTAPTNGAAGIVPAVLRYVRDICPDTSHAQLRDFLLTAAAVGALI
KRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPAQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAA
ASLALRGDGIHHVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC
>Mature_448_residues
MISVFDLFKIGIGPSSSHTVGPMVAARRFREGLPQGTRRVTAELFGSLAWTGKGHGSDTAIWLGLMGAAPDTLDPDEVPV
LTARLAIQKFIEAGGARIAFDTERDLIFDFATLLPLHSNGMRFRAFGEDGATLEERVFYSIGGGFVVEEGETREAPAQDV
PHPFATAAELLSACARAQLSIADLQMANECALRPREDVERGLDAILDAMFASIDRGLAREGALPGRLRVKRRARAIHDQL
QADRLTNQRPPHEVMDWVSVFAMAVNEENAAGGRIVTAPTNGAAGIVPAVLRYVRDICPDTSHAQLRDFLLTAAAVGALI
KRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPAQIENAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAA
ASLALRGDGIHHVSLDQVIETMRQTGADMQSKYKETSQGGLAVNVPEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=459, Percent_Identity=51.19825708061, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1788116, Length=454, Percent_Identity=51.1013215859031, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI48994925, Length=461, Percent_Identity=50.7592190889371, Blast_Score=423, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 47406; Mature: 47406

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVFDLFKIGIGPSSSHTVGPMVAARRFREGLPQGTRRVTAELFGSLAWTGKGHGSDTA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCE
IWLGLMGAAPDTLDPDEVPVLTARLAIQKFIEAGGARIAFDTERDLIFDFATLLPLHSNG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCC
MRFRAFGEDGATLEERVFYSIGGGFVVEEGETREAPAQDVPHPFATAAELLSACARAQLS
CEEEEECCCCCCHHHHHHEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IADLQMANECALRPREDVERGLDAILDAMFASIDRGLAREGALPGRLRVKRRARAIHDQL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QADRLTNQRPPHEVMDWVSVFAMAVNEENAAGGRIVTAPTNGAAGIVPAVLRYVRDICPD
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCC
TSHAQLRDFLLTAAAVGALIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPAQIE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAAASLALRGDGIHHVSLDQVIE
HHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCCHHHHHHHHEECCCCCEECCHHHHHH
TMRQTGADMQSKYKETSQGGLAVNVPEC
HHHHCCCHHHHHHHHHCCCCEEEECCCC
>Mature Secondary Structure
MISVFDLFKIGIGPSSSHTVGPMVAARRFREGLPQGTRRVTAELFGSLAWTGKGHGSDTA
CCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCE
IWLGLMGAAPDTLDPDEVPVLTARLAIQKFIEAGGARIAFDTERDLIFDFATLLPLHSNG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCC
MRFRAFGEDGATLEERVFYSIGGGFVVEEGETREAPAQDVPHPFATAAELLSACARAQLS
CEEEEECCCCCCHHHHHHEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
IADLQMANECALRPREDVERGLDAILDAMFASIDRGLAREGALPGRLRVKRRARAIHDQL
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QADRLTNQRPPHEVMDWVSVFAMAVNEENAAGGRIVTAPTNGAAGIVPAVLRYVRDICPD
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCC
TSHAQLRDFLLTAAAVGALIKRNASISGAEVGCQGEVGSAASMAAAGLAAVLGASPAQIE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHH
NAAEIAMEHHLGMTCDPIGGLVQIPCIERNAFGANKAIAAASLALRGDGIHHVSLDQVIE
HHHHHHHHHHCCCCCCCCCCEEECCEECCCCCCCCHHHHHHHHEECCCCCEECCHHHHHH
TMRQTGADMQSKYKETSQGGLAVNVPEC
HHHHCCCHHHHHHHHHCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]