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The map label for this gene is yleA [C]

Identifier: 154244369

GI number: 154244369

Start: 442417

End: 443730

Strand: Direct

Name: yleA [C]

Synonym: Xaut_0412

Alternate gene names: 154244369

Gene position: 442417-443730 (Clockwise)

Preceding gene: 154244368

Following gene: 154244370

Centisome position: 8.33

GC content: 73.67

Gene sequence:

>1314_bases
ATGGCGGCTTCTTCGGTTCCGGCCGCTTCCTCGGCGCCCGCAGCGCCGGGCACGGCCGTGCGTGTCGTCTCCTTCGGCTG
CCGGCTCAATGCGCTGGAAGGCGACGGTATCGCCCGCGCCGCCACCGCCGAGGGGCTGGAGCGCACCCTCGTGTTCAACA
CCTGCGCCGTCACGGGTGAGGCGGTGCGGCAGGCGCGGCAGGCCATCCGCCGGGCGCGGCGGGAGGATCCCGACCTGCGC
GTCATCGTCACCGGCTGCGCCGCCCAGACCGACCCGCAGGCCTTCGCCCGCATGGACGAGGTGGACCTCGTGCTGGGCAA
TGCCGACAAGACCCTTCCCGCCGCGTGGGCCACGACCCGTGCCGCCCTCGATTTCGGCATCGGCGCCGAGCAGAAGGTGC
GGGTGCAGGATATCTCGGCGGTGCGCGCGGCCACCCCCCATCTCGCCGACCGGTTCGAGGGGCACACCCGCGCCTTCGTG
GAGGTGCAGAACGGCTGCGACCACCGCTGCACCTTCTGCATCATCCCGTTCGGTCGTGGCCCCTCGCGTTCCGTGCCCAT
GGGCGCGGTGGTGGATCAGGTGCGGCGTCTGGTGGCGAACGGCCACCGCGAGGTGGTGCTCACCGGCGTCGACCTCACCG
CCTACGGTGCCGACCTGCCTGGCGCGCCCACCCTGGGCCGGCTGGTGCGCTCGGTGCTCACCGGCGTGCCGGACCTTCCC
CGCCTGCGCCTCTCCTCCATCGACGCGGTGGAGGCCGACGACGAGCTGATGCGGGCGCTGGCTGAGGAAGAGCGGCTGAT
GCCGCATCTCCACCTCTCGCTCCAGGCCGGCGACGACCTCATCCTGAAGCGCATGAAGCGCCGGCATTCCCGTGCGCAGG
CGCTGGACTTCATCTCCGCCCTGCGCCGGGCGCGTCCGGATGTGGTGCTGGGCGCCGACATCATCGCCGGCTTTCCCACC
GAGACCGAGGAACAGGCCCGCGCCACCCGCGCCTTCCTCGACGAGGCGGGCCTCGCCTTCGTCCATGTCTTCCCGTTCTC
GGCGCGGCCCGGCACCGCCGCCGCCCGCATGCCGCAGCTTCCCGCCGGCGTGGTGGCGGAGCGCGCGCGCCGGCTGCGCG
AGACCGCCGCCGACCTGCTGCGTCGTCATCTCGCAAGCGAGGTGGGCCGGCGCCGGCAGGTGCTGGTGGAGGCCGGCGGA
CGTGGCCATACCGAACATTTCACCCCGGTGCGCCTCGCCTGGCCGGCCGAGCGCGGCAGCCTCGCGGCGCTGCGCATCGC
CGGACACGACGGCGCGCGCCTGATCGCGGCGTGA

Upstream 100 bases:

>100_bases
TTTCCTGGCGCGAAGCCGACGGCCACGTGCTGATGACCGGCCCGGTGGAGCACGAGTTCTCCGGCACTCTCTCCCCGGCC
ATGCTGGAGGAGGCCGCCTG

Downstream 100 bases:

>100_bases
CCCCTCTTCAAGGAACGGCCTGAGCCATGAGCGACAACGACCGGAATTCCCCCGCTGACGCGCAGAAGAAGAAGCGCGGC
CTGTGGGGCTGGCTGAAGTC

Product: MiaB-like tRNA modifying protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MAASSVPAASSAPAAPGTAVRVVSFGCRLNALEGDGIARAATAEGLERTLVFNTCAVTGEAVRQARQAIRRARREDPDLR
VIVTGCAAQTDPQAFARMDEVDLVLGNADKTLPAAWATTRAALDFGIGAEQKVRVQDISAVRAATPHLADRFEGHTRAFV
EVQNGCDHRCTFCIIPFGRGPSRSVPMGAVVDQVRRLVANGHREVVLTGVDLTAYGADLPGAPTLGRLVRSVLTGVPDLP
RLRLSSIDAVEADDELMRALAEEERLMPHLHLSLQAGDDLILKRMKRRHSRAQALDFISALRRARPDVVLGADIIAGFPT
ETEEQARATRAFLDEAGLAFVHVFPFSARPGTAAARMPQLPAGVVAERARRLRETAADLLRRHLASEVGRRRQVLVEAGG
RGHTEHFTPVRLAWPAERGSLAALRIAGHDGARLIAA

Sequences:

>Translated_437_residues
MAASSVPAASSAPAAPGTAVRVVSFGCRLNALEGDGIARAATAEGLERTLVFNTCAVTGEAVRQARQAIRRARREDPDLR
VIVTGCAAQTDPQAFARMDEVDLVLGNADKTLPAAWATTRAALDFGIGAEQKVRVQDISAVRAATPHLADRFEGHTRAFV
EVQNGCDHRCTFCIIPFGRGPSRSVPMGAVVDQVRRLVANGHREVVLTGVDLTAYGADLPGAPTLGRLVRSVLTGVPDLP
RLRLSSIDAVEADDELMRALAEEERLMPHLHLSLQAGDDLILKRMKRRHSRAQALDFISALRRARPDVVLGADIIAGFPT
ETEEQARATRAFLDEAGLAFVHVFPFSARPGTAAARMPQLPAGVVAERARRLRETAADLLRRHLASEVGRRRQVLVEAGG
RGHTEHFTPVRLAWPAERGSLAALRIAGHDGARLIAA
>Mature_436_residues
AASSVPAASSAPAAPGTAVRVVSFGCRLNALEGDGIARAATAEGLERTLVFNTCAVTGEAVRQARQAIRRARREDPDLRV
IVTGCAAQTDPQAFARMDEVDLVLGNADKTLPAAWATTRAALDFGIGAEQKVRVQDISAVRAATPHLADRFEGHTRAFVE
VQNGCDHRCTFCIIPFGRGPSRSVPMGAVVDQVRRLVANGHREVVLTGVDLTAYGADLPGAPTLGRLVRSVLTGVPDLPR
LRLSSIDAVEADDELMRALAEEERLMPHLHLSLQAGDDLILKRMKRRHSRAQALDFISALRRARPDVVLGADIIAGFPTE
TEEQARATRAFLDEAGLAFVHVFPFSARPGTAAARMPQLPAGVVAERARRLRETAADLLRRHLASEVGRRRQVLVEAGGR
GHTEHFTPVRLAWPAERGSLAALRIAGHDGARLIAA

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MTTase N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=410, Percent_Identity=25.609756097561, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI28872782, Length=380, Percent_Identity=25.2631578947368, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI28872784, Length=380, Percent_Identity=25.2631578947368, Blast_Score=116, Evalue=5e-26,
Organism=Escherichia coli, GI1786882, Length=407, Percent_Identity=28.7469287469287, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787057, Length=400, Percent_Identity=28.25, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17553146, Length=438, Percent_Identity=26.2557077625571, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71996771, Length=266, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21356207, Length=457, Percent_Identity=27.5711159737418, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI19922432, Length=395, Percent_Identity=26.8354430379747, Blast_Score=127, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 46905; Mature: 46774

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASSVPAASSAPAAPGTAVRVVSFGCRLNALEGDGIARAATAEGLERTLVFNTCAVTGE
CCCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCHHHHHHHHHHHHHEEHHHHCCHH
AVRQARQAIRRARREDPDLRVIVTGCAAQTDPQAFARMDEVDLVLGNADKTLPAAWATTR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCCHHHHHHH
AALDFGIGAEQKVRVQDISAVRAATPHLADRFEGHTRAFVEVQNGCDHRCTFCIIPFGRG
HHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
PSRSVPMGAVVDQVRRLVANGHREVVLTGVDLTAYGADLPGAPTLGRLVRSVLTGVPDLP
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
RLRLSSIDAVEADDELMRALAEEERLMPHLHLSLQAGDDLILKRMKRRHSRAQALDFISA
CHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LRRARPDVVLGADIIAGFPTETEEQARATRAFLDEAGLAFVHVFPFSARPGTAAARMPQL
HHHCCCCEEECHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHCCCC
PAGVVAERARRLRETAADLLRRHLASEVGRRRQVLVEAGGRGHTEHFTPVRLAWPAERGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCCCCCC
LAALRIAGHDGARLIAA
EEEEEEECCCCCEEECC
>Mature Secondary Structure 
AASSVPAASSAPAAPGTAVRVVSFGCRLNALEGDGIARAATAEGLERTLVFNTCAVTGE
CCCCCCCCCCCCCCCCCEEEEEEECCEEEEECCCCCHHHHHHHHHHHHHEEHHHHCCHH
AVRQARQAIRRARREDPDLRVIVTGCAAQTDPQAFARMDEVDLVLGNADKTLPAAWATTR
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCEEEECCCCCCCCHHHHHHH
AALDFGIGAEQKVRVQDISAVRAATPHLADRFEGHTRAFVEVQNGCDHRCTFCIIPFGRG
HHHHHCCCCCCEEEHHHHHHHHHCCCHHHHHHCCCCEEEEEECCCCCCCEEEEEEECCCC
PSRSVPMGAVVDQVRRLVANGHREVVLTGVDLTAYGADLPGAPTLGRLVRSVLTGVPDLP
CCCCCCHHHHHHHHHHHHHCCCCEEEEEECEEEEECCCCCCCCHHHHHHHHHHHCCCCCC
RLRLSSIDAVEADDELMRALAEEERLMPHLHLSLQAGDDLILKRMKRRHSRAQALDFISA
CHHHCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LRRARPDVVLGADIIAGFPTETEEQARATRAFLDEAGLAFVHVFPFSARPGTAAARMPQL
HHHCCCCEEECHHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCCCHHHHCCCC
PAGVVAERARRLRETAADLLRRHLASEVGRRRQVLVEAGGRGHTEHFTPVRLAWPAERGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCEEEECCCCCCC
LAALRIAGHDGARLIAA
EEEEEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]