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The map label for this gene is ftsY [H]

Identifier: 154244370

GI number: 154244370

Start: 443757

End: 445346

Strand: Direct

Name: ftsY [H]

Synonym: Xaut_0413

Alternate gene names: 154244370

Gene position: 443757-445346 (Clockwise)

Preceding gene: 154244369

Following gene: 154244371

Centisome position: 8.36

GC content: 71.07

Gene sequence:

>1590_bases
ATGAGCGACAACGACCGGAATTCCCCCGCTGACGCGCAGAAGAAGAAGCGCGGCCTGTGGGGCTGGCTGAAGTCCGGTTT
TGAGGATCCCGTCCCGCGCTTCACCCATGAGACCCCGCAGGAGGCCGGCGCGCCGGCTGACGAGGGGCGCGAGGCTGCGC
CCGCGCCGTCGGGCGATGCCGCGGCCGTGACCGGCGAGGCTTCATCCACGACGCCCGTCCCCGCCGCCGAAGTCGGACCG
GAAGCAGCGCCTGCGCCGGTGGCCGAGGTGCCGCCCCCGGTCCCTGTGGAGGTCCCCGTGGCGCCCGCAGGCGGCCCGGC
TTTCGGTGCGCAGATCGAACAGCCGCCGGCCCCCACCGTGGTGCCTGTCCCTCCGGCCGTGGCTGAATCGACGTCCGAAG
CGGTTCGGGTTCCCATGGCTGAGCCGGAGCCCGAGGCGCCGGTCGCCGAAGCCCCGCCGGCCATCGCATCCGAGAGCGTG
GAAGCCAGCGCGCCAGCCTTTGAGGCGCCGCCCGAAGAAGCGCCTGTTCTCGAAGCCCCCATTGTTGAGGCGGAGCCCGC
GCCCGAGGTCCCGCCTCCCGCCGTCGAGCCTGCGCTGGTCGATGTGCCGCAGCAGCTTCCGGTGGAGCCCGAGCCTGTCG
CCGACGGTCCCGCCGCCGAGCCTCAGCCGGCGAAGAAAGGCTTCTGGAGCCGGCTTGCCTCGGGCCTCGCCCGCACCGCG
TCCAGCCTCGGGCAGGGCATCACCGACCTCGTTTCCAAGCGCAAGCTCGATGCCGACACGCTGGAAGAGCTGGAGGACGT
GCTCATCCGCGCCGATCTCGGCGTGGAGACCTCCATGCGCATCGTGGAGACGGTGGGCAAGGGCCGGCACGACAAGATGA
TCTCCCCCGAGGAGGTGAAGCGCCTCATTGCGGAGGAGGTGGAGCGCATCCTCATTCCGGTGGCGCAGCCGCTGGTGGTG
GATACGGCGCACAAGCCCTTCGTGGTGCTGATGGTGGGGGTGAACGGTTCGGGCAAGACCACCACCATCGGCAAGCTCGC
CGCCCAGTGGCGCACCGAAGGCAAAAAGGTGGTGCTCGCCGCCGGCGACACCTTCCGTGCCGCCGCCATCGAGCAACTGA
AGGTGTGGGGCACCCGCACCGGCGCCACCGTCATCGCCCGCGAGCAGGGCTCCGATGCCGCCGGCGTCGCCCATGAGGCG
GTGGTGGAGGCGCGCGCGGCCGGGGCCGACATCCTTATGGTGGACACCGCCGGCCGCCTCCAGAACCGCACCGAGCTGAT
GGCGGAGCTGGAGAAGGTGGTGCGCGTCATCAAGAAGCTGGAGCCCTCGGCGCCCCACGCAGTGCTTCTGGTGCTCGACG
CCACGGTGGGCCAGAACGCGCTGTCGCAGGTGGAAGCCTTCACCCGCATCGCCGGGGTGACCGGGATGGTCATGACCAAG
CTCGACGGCACGGCGCGTGGTGGCATCCTGGTGGCCATCGCCGCCAAGCACAAGCTGCCGGTGCACCTCATCGGCGTGGG
CGAGGCGGCCGAGGACCTCCAGCCCTTCGCCGCCCGGGATTTTGCCCGCGCCATCGCCGGGTTGAACTGA

Upstream 100 bases:

>100_bases
GGCCGGCCGAGCGCGGCAGCCTCGCGGCGCTGCGCATCGCCGGACACGACGGCGCGCGCCTGATCGCGGCGTGACCCCTC
TTCAAGGAACGGCCTGAGCC

Downstream 100 bases:

>100_bases
GGGCGGCCGAGCCGGGAGCAGGCTGGGGCGGCCGCTATTGCCTCGCCCGGGATGGTGCGGCTATGTTTGCGTACAATATT
TGAAATTGTATGGCTCGTGG

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSDNDRNSPADAQKKKRGLWGWLKSGFEDPVPRFTHETPQEAGAPADEGREAAPAPSGDAAAVTGEASSTTPVPAAEVGP
EAAPAPVAEVPPPVPVEVPVAPAGGPAFGAQIEQPPAPTVVPVPPAVAESTSEAVRVPMAEPEPEAPVAEAPPAIASESV
EASAPAFEAPPEEAPVLEAPIVEAEPAPEVPPPAVEPALVDVPQQLPVEPEPVADGPAAEPQPAKKGFWSRLASGLARTA
SSLGQGITDLVSKRKLDADTLEELEDVLIRADLGVETSMRIVETVGKGRHDKMISPEEVKRLIAEEVERILIPVAQPLVV
DTAHKPFVVLMVGVNGSGKTTTIGKLAAQWRTEGKKVVLAAGDTFRAAAIEQLKVWGTRTGATVIAREQGSDAAGVAHEA
VVEARAAGADILMVDTAGRLQNRTELMAELEKVVRVIKKLEPSAPHAVLLVLDATVGQNALSQVEAFTRIAGVTGMVMTK
LDGTARGGILVAIAAKHKLPVHLIGVGEAAEDLQPFAARDFARAIAGLN

Sequences:

>Translated_529_residues
MSDNDRNSPADAQKKKRGLWGWLKSGFEDPVPRFTHETPQEAGAPADEGREAAPAPSGDAAAVTGEASSTTPVPAAEVGP
EAAPAPVAEVPPPVPVEVPVAPAGGPAFGAQIEQPPAPTVVPVPPAVAESTSEAVRVPMAEPEPEAPVAEAPPAIASESV
EASAPAFEAPPEEAPVLEAPIVEAEPAPEVPPPAVEPALVDVPQQLPVEPEPVADGPAAEPQPAKKGFWSRLASGLARTA
SSLGQGITDLVSKRKLDADTLEELEDVLIRADLGVETSMRIVETVGKGRHDKMISPEEVKRLIAEEVERILIPVAQPLVV
DTAHKPFVVLMVGVNGSGKTTTIGKLAAQWRTEGKKVVLAAGDTFRAAAIEQLKVWGTRTGATVIAREQGSDAAGVAHEA
VVEARAAGADILMVDTAGRLQNRTELMAELEKVVRVIKKLEPSAPHAVLLVLDATVGQNALSQVEAFTRIAGVTGMVMTK
LDGTARGGILVAIAAKHKLPVHLIGVGEAAEDLQPFAARDFARAIAGLN
>Mature_528_residues
SDNDRNSPADAQKKKRGLWGWLKSGFEDPVPRFTHETPQEAGAPADEGREAAPAPSGDAAAVTGEASSTTPVPAAEVGPE
AAPAPVAEVPPPVPVEVPVAPAGGPAFGAQIEQPPAPTVVPVPPAVAESTSEAVRVPMAEPEPEAPVAEAPPAIASESVE
ASAPAFEAPPEEAPVLEAPIVEAEPAPEVPPPAVEPALVDVPQQLPVEPEPVADGPAAEPQPAKKGFWSRLASGLARTAS
SLGQGITDLVSKRKLDADTLEELEDVLIRADLGVETSMRIVETVGKGRHDKMISPEEVKRLIAEEVERILIPVAQPLVVD
TAHKPFVVLMVGVNGSGKTTTIGKLAAQWRTEGKKVVLAAGDTFRAAAIEQLKVWGTRTGATVIAREQGSDAAGVAHEAV
VEARAAGADILMVDTAGRLQNRTELMAELEKVVRVIKKLEPSAPHAVLLVLDATVGQNALSQVEAFTRIAGVTGMVMTKL
DGTARGGILVAIAAKHKLPVHLIGVGEAAEDLQPFAARDFARAIAGLN

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=272, Percent_Identity=31.6176470588235, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI226371618, Length=241, Percent_Identity=32.7800829875519, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI295424842, Length=294, Percent_Identity=29.2517006802721, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI23308697, Length=294, Percent_Identity=29.2517006802721, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI89061728, Length=137, Percent_Identity=32.1167883211679, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789874, Length=318, Percent_Identity=49.3710691823899, Blast_Score=301, Evalue=8e-83,
Organism=Escherichia coli, GI1788963, Length=309, Percent_Identity=33.0097087378641, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17539958, Length=290, Percent_Identity=30.3448275862069, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=304, Percent_Identity=31.25, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6325345, Length=252, Percent_Identity=32.5396825396825, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6320498, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647949, Length=280, Percent_Identity=30.3571428571429, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24641198, Length=358, Percent_Identity=29.0502793296089, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 54757; Mature: 54626

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNDRNSPADAQKKKRGLWGWLKSGFEDPVPRFTHETPQEAGAPADEGREAAPAPSGDA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
AAVTGEASSTTPVPAAEVGPEAAPAPVAEVPPPVPVEVPVAPAGGPAFGAQIEQPPAPTV
EEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCE
VPVPPAVAESTSEAVRVPMAEPEPEAPVAEAPPAIASESVEASAPAFEAPPEEAPVLEAP
EECCCHHHHCCHHHEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
IVEAEPAPEVPPPAVEPALVDVPQQLPVEPEPVADGPAAEPQPAKKGFWSRLASGLARTA
CCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SSLGQGITDLVSKRKLDADTLEELEDVLIRADLGVETSMRIVETVGKGRHDKMISPEEVK
HHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
RLIAEEVERILIPVAQPLVVDTAHKPFVVLMVGVNGSGKTTTIGKLAAQWRTEGKKVVLA
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEE
AGDTFRAAAIEQLKVWGTRTGATVIAREQGSDAAGVAHEAVVEARAAGADILMVDTAGRL
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
QNRTELMAELEKVVRVIKKLEPSAPHAVLLVLDATVGQNALSQVEAFTRIAGVTGMVMTK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCHHHHHHHHHHHHHHHHHHHHHEE
LDGTARGGILVAIAAKHKLPVHLIGVGEAAEDLQPFAARDFARAIAGLN
CCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDNDRNSPADAQKKKRGLWGWLKSGFEDPVPRFTHETPQEAGAPADEGREAAPAPSGDA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCC
AAVTGEASSTTPVPAAEVGPEAAPAPVAEVPPPVPVEVPVAPAGGPAFGAQIEQPPAPTV
EEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCE
VPVPPAVAESTSEAVRVPMAEPEPEAPVAEAPPAIASESVEASAPAFEAPPEEAPVLEAP
EECCCHHHHCCHHHEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCC
IVEAEPAPEVPPPAVEPALVDVPQQLPVEPEPVADGPAAEPQPAKKGFWSRLASGLARTA
CCCCCCCCCCCCCCCCCHHHCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SSLGQGITDLVSKRKLDADTLEELEDVLIRADLGVETSMRIVETVGKGRHDKMISPEEVK
HHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCHHHHH
RLIAEEVERILIPVAQPLVVDTAHKPFVVLMVGVNGSGKTTTIGKLAAQWRTEGKKVVLA
HHHHHHHHHHHHHCCCCEEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEE
AGDTFRAAAIEQLKVWGTRTGATVIAREQGSDAAGVAHEAVVEARAAGADILMVDTAGRL
CCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHH
QNRTELMAELEKVVRVIKKLEPSAPHAVLLVLDATVGQNALSQVEAFTRIAGVTGMVMTK
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECHHCHHHHHHHHHHHHHHHHHHHHHEE
LDGTARGGILVAIAAKHKLPVHLIGVGEAAEDLQPFAARDFARAIAGLN
CCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]