Click here to switch to the map view.

The map label for this gene is hycD [H]

Identifier: 154244125

GI number: 154244125

Start: 163829

End: 164782

Strand: Direct

Name: hycD [H]

Synonym: Xaut_0167

Alternate gene names: 154244125

Gene position: 163829-164782 (Clockwise)

Preceding gene: 154244124

Following gene: 154244126

Centisome position: 3.09

GC content: 68.45

Gene sequence:

>954_bases
ATGGACCTGATGGCGCACATCCTGGTGCAGGGCACGCAGATGCTGCTCGTGCTCGCCCTCGCCCCGCTCCTCACCGGGCT
GGTGCGCAAGGTGAAGGCGCGCCTCCAGCGCCGGCGCGGCGCCTCCGTGTTCCAGCCCTACCGCGACCTCGCCCGGCTGC
TGCGCAAGGAGGCGGTGCTGGCGCAGAACGCCTCCTGGCTGTTCCGCGTGGTGCCTTATCTCGTGTTCGCGGCCACCTGG
GTGGCGGCGGCGCTGGTGCCGACCTTCGCCACCGGACTGATCTTTTCCTGGTCGGCGGACCTCATCGCCATCACCGCCCT
CATCGGCTCGGCGCGCTTCTTCCTGGCGTTGGCCGGCATGGATGTGGGCACCAGCTTCGGCGGCCTCGGATCGAGCCGGG
AGGTGATGATCTCCTCGCTGGCCGAGCCGGCCATGATCATGATCGTGTTCTCCCTGGCCCTCGTCGCCCATTCCACCCAG
CTCTCCACCATCGCCTCGGTGATGCTGGCCGGCGTGGGCCTCAGGGTGTCGCTGGCGTTGGCGCTGGTGGCGCTGCTGAT
GGTGGCAGTGGCCGAGAACGGCCGCATCCCGGTGGACAATCCCTCCACCCATCTGGAGCTCACCATGGTGCATGAAGCCA
TGGTGCTGGAATATTCCGGCCGCCACCTGGCGCTGATCGAGCTGGCCGCGCAGCTGAAGCTGCTGCTGTTCCTTTCGCTT
GTGGCCTGCGTGTTCGTGCCGTGGGGCCTTGCCCCGGTGGGGGCGGGTGTCGCCGGAATGGTGCTGGGGATGGCGACCTA
TGCCGGCAAGCTCGCCGTGGGCGCGCTGCTCCTCGCCGTGTTCGAGACCTCCATCGCCAAGATGCGGGTGTTCCGCGTGC
CGGACTTCCTCGGCGCGGCGCTCATGCTCGGGCTGTTGGGAACGCTGCTGCTGTTCGTGTCGGGGATCCTGTGA

Upstream 100 bases:

>100_bases
ATGTGGCCGAGCGGGCGAACCGGCTGCAATACCTCACCATCCGCCAGTATCTGGGCCTGGTTTTTTCGGCCCTGGTGCTG
CTGCTTCTGGTGCTCGCCCT

Downstream 100 bases:

>100_bases
TGATCGAGCACGCCATCACCCCCAATCTCGTCTTCGACGTGTCCCACATGTTCGCGGGCGGGCTGGTGCTCATCTCCTTC
CTGATGCTCTACCAGGACCG

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MDLMAHILVQGTQMLLVLALAPLLTGLVRKVKARLQRRRGASVFQPYRDLARLLRKEAVLAQNASWLFRVVPYLVFAATW
VAAALVPTFATGLIFSWSADLIAITALIGSARFFLALAGMDVGTSFGGLGSSREVMISSLAEPAMIMIVFSLALVAHSTQ
LSTIASVMLAGVGLRVSLALALVALLMVAVAENGRIPVDNPSTHLELTMVHEAMVLEYSGRHLALIELAAQLKLLLFLSL
VACVFVPWGLAPVGAGVAGMVLGMATYAGKLAVGALLLAVFETSIAKMRVFRVPDFLGAALMLGLLGTLLLFVSGIL

Sequences:

>Translated_317_residues
MDLMAHILVQGTQMLLVLALAPLLTGLVRKVKARLQRRRGASVFQPYRDLARLLRKEAVLAQNASWLFRVVPYLVFAATW
VAAALVPTFATGLIFSWSADLIAITALIGSARFFLALAGMDVGTSFGGLGSSREVMISSLAEPAMIMIVFSLALVAHSTQ
LSTIASVMLAGVGLRVSLALALVALLMVAVAENGRIPVDNPSTHLELTMVHEAMVLEYSGRHLALIELAAQLKLLLFLSL
VACVFVPWGLAPVGAGVAGMVLGMATYAGKLAVGALLLAVFETSIAKMRVFRVPDFLGAALMLGLLGTLLLFVSGIL
>Mature_317_residues
MDLMAHILVQGTQMLLVLALAPLLTGLVRKVKARLQRRRGASVFQPYRDLARLLRKEAVLAQNASWLFRVVPYLVFAATW
VAAALVPTFATGLIFSWSADLIAITALIGSARFFLALAGMDVGTSFGGLGSSREVMISSLAEPAMIMIVFSLALVAHSTQ
LSTIASVMLAGVGLRVSLALALVALLMVAVAENGRIPVDNPSTHLELTMVHEAMVLEYSGRHLALIELAAQLKLLLFLSL
VACVFVPWGLAPVGAGVAGMVLGMATYAGKLAVGALLLAVFETSIAKMRVFRVPDFLGAALMLGLLGTLLLFVSGIL

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=284, Percent_Identity=35.5633802816901, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI87082115, Length=239, Percent_Identity=35.5648535564854, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33550; Mature: 33550

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLMAHILVQGTQMLLVLALAPLLTGLVRKVKARLQRRRGASVFQPYRDLARLLRKEAVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AQNASWLFRVVPYLVFAATWVAAALVPTFATGLIFSWSADLIAITALIGSARFFLALAGM
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
DVGTSFGGLGSSREVMISSLAEPAMIMIVFSLALVAHSTQLSTIASVMLAGVGLRVSLAL
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALVALLMVAVAENGRIPVDNPSTHLELTMVHEAMVLEYSGRHLALIELAAQLKLLLFLSL
HHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VACVFVPWGLAPVGAGVAGMVLGMATYAGKLAVGALLLAVFETSIAKMRVFRVPDFLGAA
HHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMLGLLGTLLLFVSGIL
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLMAHILVQGTQMLLVLALAPLLTGLVRKVKARLQRRRGASVFQPYRDLARLLRKEAVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AQNASWLFRVVPYLVFAATWVAAALVPTFATGLIFSWSADLIAITALIGSARFFLALAGM
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
DVGTSFGGLGSSREVMISSLAEPAMIMIVFSLALVAHSTQLSTIASVMLAGVGLRVSLAL
CCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ALVALLMVAVAENGRIPVDNPSTHLELTMVHEAMVLEYSGRHLALIELAAQLKLLLFLSL
HHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
VACVFVPWGLAPVGAGVAGMVLGMATYAGKLAVGALLLAVFETSIAKMRVFRVPDFLGAA
HHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LMLGLLGTLLLFVSGIL
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]