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The map label for this gene is xcpR [H]

Identifier: 153949834

GI number: 153949834

Start: 4205801

End: 4207354

Strand: Reverse

Name: xcpR [H]

Synonym: YpsIP31758_3731

Alternate gene names: 153949834

Gene position: 4207354-4205801 (Counterclockwise)

Preceding gene: 153948141

Following gene: 153949596

Centisome position: 89.08

GC content: 52.12

Gene sequence:

>1554_bases
ATGATTATTGATAAGGATATCAGGGAGTTTGTCTTTGTTGATCATCTGCCCTGTGGGCAAGTCGTGCTGGTTATTGATAA
CAATCGACGCACTGACCCACGGGTACAGCGCTGGGTGGTGGAAATGGCGCGTATTCACACCGGCGCTAAAAACGAGTTTA
TGCCCCTCAGTGAATTGAATAACCGCCGCGCCCGTATAGCTGATAGTTCGCAATATAGTATTTGCTTGAAAGACCTGACT
AACATCAGCGAGCGGCAGAAAAAAGTGCTGCATTATTTTGAATTGTCGCGCGAGCTTAGGGCTTCAGATATCCATCTCAT
CATCGACAGCCAATTGGCTCGGGTAGAAATGCGTTTACATGGTGATCTGGAAGAGGTGGATTCTCTGCCAAGGGGGGAGG
GGATGGCGCTGGCTTCAACCATCATTCTCTCGATGTGCGATGTGGCTGAGACACAGTTTTATCCTGGGCGAGAACAGGGT
GGGCGCGTAAAATCTGACTTTGCTCGCAAAGTCGGTGTTTTTGGTGCGCGTTATGAGCATCGCCCAACGGCCGACGGCCT
TTATGTCGTCATGCGGATTATCGATGATGACGGTGATGCAGTACCGACGTTGAATACGTTAGGATTTATGCCAGAACAGC
GCACGCTGGTAGAGAAAATTCTACGTATCCCGGAGGGGATGGTGATCCTCTCTGGCCCTACAGGGGCGGGGAAAAGTACC
ACTTTACGTAGCTTCAGCCAGATGTATTTGGATCGCACCGGTGGACGGCGTCGGTTGCTGACGATTGAAGACCCGCCGGA
AGGGAGAATCAAAGGCGCGATACAGACGCCCATCATTGCCGATAAAAGCCGTACCGATGTTGTTCAGCAAGCCTGGAATA
GCGCCAATGCTTCTGCTTTACGCCTCGATCCTGATGCCATTCTTAACGGCGAAATGCGTGACCTCATCTCTATCGTAGCT
GCCGTTTATGCGGCTCAAACGGGCCATTTGCTTCTGACAACGCTTCACGCCAACAGTGCTGTTGGCATTCTCAAACGCAT
GGTCGTTTTGGGTGTTTCGGAGGCACTTATCGCGGATGCCCAGCTTATCGTGGGGCTTATCAGCCAGCGCCTTGTTCAAA
CGCTGTGTACGTATTGTCGCATTCCCTGGAAAGCCAAGGCCCCGCGACTCACACCTGAAATCCGTATGCGCCTCGAACGT
TATTGTTGTGTGGAGGGCGTTTGTCGTCCTGAACAACTGTGGTTTCGTAGTGAGGAAGGATGTGTGCATTGCCAGCAACG
GCTTTCTATCAGTGATCGTATCGTCAGCCGCGGTGTGACCGGGCGCAGTGTGGTGGCGGAGGTGATTCGCCCTGATGCGC
GATTTATGTCGCTGTATCTGGCTCACGGCCCGGCAGTGGCCAGACAATACTGGGTTAAATCGCTAAGAGGCATAACGCGT
GTGACTCATCTGTTACATCAATTGGCTGCGGGTCTGGTTGATCCCCTTGATGCAGATTTGATCTGTCCACTAGATGAAGA
TCACCTCTTGACCGGTGAGGTGCCTGATGTCTGA

Upstream 100 bases:

>100_bases
AGGTGATATTTTGCCTGGCAGTTCTCTCAAGATAACGGCGATTACAGCGTCGGTGGTGAAACTGAGTGACGGCACTGTGA
TGTCATTCTGAGGCGAAAAA

Downstream 100 bases:

>100_bases
GATGATTTTTCGTCCTGCCCGAAATATGTCTTTGGCGAAACGCCTACGGTATGAGTTGGTGCGCCATACTTTTAGTGCTC
ATTACCGCCTGGAGTTTTAT

Product: type IV secretion system protein

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MIIDKDIREFVFVDHLPCGQVVLVIDNNRRTDPRVQRWVVEMARIHTGAKNEFMPLSELNNRRARIADSSQYSICLKDLT
NISERQKKVLHYFELSRELRASDIHLIIDSQLARVEMRLHGDLEEVDSLPRGEGMALASTIILSMCDVAETQFYPGREQG
GRVKSDFARKVGVFGARYEHRPTADGLYVVMRIIDDDGDAVPTLNTLGFMPEQRTLVEKILRIPEGMVILSGPTGAGKST
TLRSFSQMYLDRTGGRRRLLTIEDPPEGRIKGAIQTPIIADKSRTDVVQQAWNSANASALRLDPDAILNGEMRDLISIVA
AVYAAQTGHLLLTTLHANSAVGILKRMVVLGVSEALIADAQLIVGLISQRLVQTLCTYCRIPWKAKAPRLTPEIRMRLER
YCCVEGVCRPEQLWFRSEEGCVHCQQRLSISDRIVSRGVTGRSVVAEVIRPDARFMSLYLAHGPAVARQYWVKSLRGITR
VTHLLHQLAAGLVDPLDADLICPLDEDHLLTGEVPDV

Sequences:

>Translated_517_residues
MIIDKDIREFVFVDHLPCGQVVLVIDNNRRTDPRVQRWVVEMARIHTGAKNEFMPLSELNNRRARIADSSQYSICLKDLT
NISERQKKVLHYFELSRELRASDIHLIIDSQLARVEMRLHGDLEEVDSLPRGEGMALASTIILSMCDVAETQFYPGREQG
GRVKSDFARKVGVFGARYEHRPTADGLYVVMRIIDDDGDAVPTLNTLGFMPEQRTLVEKILRIPEGMVILSGPTGAGKST
TLRSFSQMYLDRTGGRRRLLTIEDPPEGRIKGAIQTPIIADKSRTDVVQQAWNSANASALRLDPDAILNGEMRDLISIVA
AVYAAQTGHLLLTTLHANSAVGILKRMVVLGVSEALIADAQLIVGLISQRLVQTLCTYCRIPWKAKAPRLTPEIRMRLER
YCCVEGVCRPEQLWFRSEEGCVHCQQRLSISDRIVSRGVTGRSVVAEVIRPDARFMSLYLAHGPAVARQYWVKSLRGITR
VTHLLHQLAAGLVDPLDADLICPLDEDHLLTGEVPDV
>Mature_517_residues
MIIDKDIREFVFVDHLPCGQVVLVIDNNRRTDPRVQRWVVEMARIHTGAKNEFMPLSELNNRRARIADSSQYSICLKDLT
NISERQKKVLHYFELSRELRASDIHLIIDSQLARVEMRLHGDLEEVDSLPRGEGMALASTIILSMCDVAETQFYPGREQG
GRVKSDFARKVGVFGARYEHRPTADGLYVVMRIIDDDGDAVPTLNTLGFMPEQRTLVEKILRIPEGMVILSGPTGAGKST
TLRSFSQMYLDRTGGRRRLLTIEDPPEGRIKGAIQTPIIADKSRTDVVQQAWNSANASALRLDPDAILNGEMRDLISIVA
AVYAAQTGHLLLTTLHANSAVGILKRMVVLGVSEALIADAQLIVGLISQRLVQTLCTYCRIPWKAKAPRLTPEIRMRLER
YCCVEGVCRPEQLWFRSEEGCVHCQQRLSISDRIVSRGVTGRSVVAEVIRPDARFMSLYLAHGPAVARQYWVKSLRGITR
VTHLLHQLAAGLVDPLDADLICPLDEDHLLTGEVPDV

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=357, Percent_Identity=30.5322128851541, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786296, Length=353, Percent_Identity=32.2946175637394, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87082188, Length=163, Percent_Identity=34.9693251533742, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 57839; Mature: 57839

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDKDIREFVFVDHLPCGQVVLVIDNNRRTDPRVQRWVVEMARIHTGAKNEFMPLSELN
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHC
NRRARIADSSQYSICLKDLTNISERQKKVLHYFELSRELRASDIHLIIDSQLARVEMRLH
CCCEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHC
GDLEEVDSLPRGEGMALASTIILSMCDVAETQFYPGREQGGRVKSDFARKVGVFGARYEH
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
RPTADGLYVVMRIIDDDGDAVPTLNTLGFMPEQRTLVEKILRIPEGMVILSGPTGAGKST
CCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHH
TLRSFSQMYLDRTGGRRRLLTIEDPPEGRIKGAIQTPIIADKSRTDVVQQAWNSANASAL
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCEE
RLDPDAILNGEMRDLISIVAAVYAAQTGHLLLTTLHANSAVGILKRMVVLGVSEALIADA
EECHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHH
QLIVGLISQRLVQTLCTYCRIPWKAKAPRLTPEIRMRLERYCCVEGVCRPEQLWFRSEEG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
CVHCQQRLSISDRIVSRGVTGRSVVAEVIRPDARFMSLYLAHGPAVARQYWVKSLRGITR
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VTHLLHQLAAGLVDPLDADLICPLDEDHLLTGEVPDV
HHHHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCC
>Mature Secondary Structure
MIIDKDIREFVFVDHLPCGQVVLVIDNNRRTDPRVQRWVVEMARIHTGAKNEFMPLSELN
CCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHC
NRRARIADSSQYSICLKDLTNISERQKKVLHYFELSRELRASDIHLIIDSQLARVEMRLH
CCCEECCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHC
GDLEEVDSLPRGEGMALASTIILSMCDVAETQFYPGREQGGRVKSDFARKVGVFGARYEH
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
RPTADGLYVVMRIIDDDGDAVPTLNTLGFMPEQRTLVEKILRIPEGMVILSGPTGAGKST
CCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHH
TLRSFSQMYLDRTGGRRRLLTIEDPPEGRIKGAIQTPIIADKSRTDVVQQAWNSANASAL
HHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCEE
RLDPDAILNGEMRDLISIVAAVYAAQTGHLLLTTLHANSAVGILKRMVVLGVSEALIADA
EECHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHH
QLIVGLISQRLVQTLCTYCRIPWKAKAPRLTPEIRMRLERYCCVEGVCRPEQLWFRSEEG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCC
CVHCQQRLSISDRIVSRGVTGRSVVAEVIRPDARFMSLYLAHGPAVARQYWVKSLRGITR
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHH
VTHLLHQLAAGLVDPLDADLICPLDEDHLLTGEVPDV
HHHHHHHHHHHHCCCCCCCEECCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]