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The map label for this gene is sstT

Identifier: 153949304

GI number: 153949304

Start: 571228

End: 572484

Strand: Reverse

Name: sstT

Synonym: YpsIP31758_0495

Alternate gene names: 153949304

Gene position: 572484-571228 (Counterclockwise)

Preceding gene: 153948194

Following gene: 153949342

Centisome position: 12.12

GC content: 48.93

Gene sequence:

>1257_bases
ATGGAAAAGACACAGTCTGTATTTATACGATTTATCGTCAACGGTAGTTTAGTGAAACAAATACTGATCGGTTTAGTTGC
CGGTATTGTTTTAGCATTAGTATCGACTCCTGCAGCGATAGCGGTAGGGTTACTCGGTTCGCTGTTCGTGGGCGCATTAA
AAGCCGTCGCGCCAGTTTTAGTCTTGATGTTGGTCATAGCATCCATCGCCAACCATAAGAAAGGCCAAAAAACCAGTATT
CGCCCTATTCTGTTCCTGTATGTATTAGGGGCATTCTCTGCGGCACTGGTTGCGGTTGTCGTCAGTTTTATCTACCCATC
AACCCTTATTTTGGTGGCTGAGAGTGCTGATATCACCCCACCGAGTGGGATTGTTGAAGTGCTACACGGTTTGCTAAACA
GCATAATCGCCAACCCTATCCATGCGCTGCTCAATGCTAACTACATTGGTATTCTGGCTTGGGCTGTGGGTTTAGGTATT
GCCTTGCGCCATGCTGCCGACACCACCAAAGCATTGATTAATGATATGTCAGATGCCGTCACTTTGGTGGTCCGTGTGGT
TATCCGTTTTGCACCGTTGGGTATTTTTGGTTTGGTCGCTTCCACTATCGCAGCTACCGGCTTCGGTGCCTTACAGCTTT
ATGTGCAACTGTTAGTGGTATTGATCGGCTGTATGTTACTGGTGGCATTAGTGGTCAACCCACTGATTGTCTACTGGAAG
ATTCGCCGTAATCCTTATCCATTGGTGTTTGCTTGCCTGCGTGAAAGTGGCGTTACCGCCTTCTTTACCCGTAGCTCAGC
CGCAAACATTCCAGTGAATATGGAAATGTGTAAGAAAATGAACCTGAATGAAGACACCTATTCGATCTCCATTCCGTTAG
GTGCCACCATCAATATGGCTGGTGCAGCCATCACCATCACGGTGCTGACACTGGCGGCGGTTCATACCCTAGGCATTACC
GTTGACCTGCCAACAGCCCTGCTACTGAGTGTGGTTGCTGCGGTCTGTGCCTGTGGTGCATCCGGTGTTGCTGGTGGCTC
TCTGTTACTGATCCCACTGGCTTGTAGCATGTTCGGCATTCCAAACGATGTGGCAATGCAAGTGGTTGGTGTTGGCTTCA
TTATCGGCGTATTACAGGATTCAGCCGAAACTGCGCTGAACTCTTCAACCGATGTGTTGTTTACTGCGGCGGTCTGTCAG
GCTGAGGATGCCAAACTGGCTAATCCTGACGCACTGGCAGCGGGTAAGTCAGTCTAA

Upstream 100 bases:

>100_bases
GTATGGAGAGCAGCTAGCACCGCTGCAACTTCAGGTAATGAAGGGTATAAACGGGCAGAACATATTAAATTTCACTTGGG
AAGAGGCATTGCTAGAAGCT

Downstream 100 bases:

>100_bases
ATACCCGGTTTTACCTACGCGTAATGCCAGTTAGTTAAGTCTGACTGGCATTTTTTTGTTATCAAATCAGGCCTTTTTCT
CAATCTCAAAAGGATCTATT

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDALAAGKSV

Sequences:

>Translated_418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDALAAGKSV
>Mature_418_residues
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVLVLMLVIASIANHKKGQKTSI
RPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITPPSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGI
ALRHAADTTKALINDMSDAVTLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWK
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMAGAAITITVLTLAAVHTLGIT
VDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGIPNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQ
AEDAKLANPDALAAGKSV

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=27.9527559055118, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI223468566, Length=254, Percent_Identity=27.9527559055118, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5032093, Length=254, Percent_Identity=27.9527559055118, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4827012, Length=275, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI169790839, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI66773030, Length=272, Percent_Identity=24.6323529411765, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI21314632, Length=259, Percent_Identity=26.6409266409266, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI40254478, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1789473, Length=407, Percent_Identity=76.6584766584767, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1790514, Length=439, Percent_Identity=23.4624145785877, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789947, Length=391, Percent_Identity=24.0409207161125, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=470, Percent_Identity=22.9787234042553, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71996953, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71983106, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=299, Percent_Identity=27.7591973244147, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583025, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137668, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583023, Length=279, Percent_Identity=27.5985663082437, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_YERP3 (A7FE10)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001399488.1
- ProteinModelPortal:   A7FE10
- SMR:   A7FE10
- STRING:   A7FE10
- GeneID:   5387925
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_0495
- NMPDR:   fig|349747.3.peg.2049
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   THIRPIL
- ProtClustDB:   PRK13628
- BioCyc:   YPSE349747:YPSIP31758_0495-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 43160; Mature: 43160

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2; PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d117284)-; HASH(0x1cbda8b8)-; HASH(0x1dac1fec)-; HASH(0x1dcf1544)-; HASH(0x1d7aca08)-; HASH(0x1cbdaa2c)-; HASH(0x1dceca80)-; HASH(0x1dceb230)-;

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVL
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VLMLVIASIANHKKGQKTSIRPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCC
PSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITVLTLAAVHTLGITVDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGI
CHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
PNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDALAAGKSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH
>Mature Secondary Structure
MEKTQSVFIRFIVNGSLVKQILIGLVAGIVLALVSTPAAIAVGLLGSLFVGALKAVAPVL
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
VLMLVIASIANHKKGQKTSIRPILFLYVLGAFSAALVAVVVSFIYPSTLILVAESADITP
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCC
PSGIVEVLHGLLNSIIANPIHALLNANYIGILAWAVGLGIALRHAADTTKALINDMSDAV
CHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLVVRVVIRFAPLGIFGLVASTIAATGFGALQLYVQLLVVLIGCMLLVALVVNPLIVYWK
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEE
IRRNPYPLVFACLRESGVTAFFTRSSAANIPVNMEMCKKMNLNEDTYSISIPLGATINMA
ECCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCEEECC
GAAITITVLTLAAVHTLGITVDLPTALLLSVVAAVCACGASGVAGGSLLLIPLACSMFGI
CHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCC
PNDVAMQVVGVGFIIGVLQDSAETALNSSTDVLFTAAVCQAEDAKLANPDALAAGKSV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA