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The map label for this gene is mecA2 [H]

Identifier: 152975013

GI number: 152975013

Start: 1326676

End: 1327278

Strand: Direct

Name: mecA2 [H]

Synonym: Bcer98_1213

Alternate gene names: 152975013

Gene position: 1326676-1327278 (Clockwise)

Preceding gene: 152975012

Following gene: 152975014

Centisome position: 32.46

GC content: 35.32

Gene sequence:

>603_bases
ATGAGGTTGGAACGCTTGAATTATAATAAAATAAAAATTTTCCTAACATTTGATGATTTATCAGAACGTGGATTGACCAA
GGAAGATTTATGGAGAAACGCACCGAAAGTGCAGCAATTATTCCGTGATATGATGCAAGAAGCGAATAAAGAACTTGGAT
TTGAAGCAAATGGCCCAGTTGCTGTTGAAGTATTTTCCTTACAAGCGCAAGGGATGGTTGTAATTGTAACAAAAGAAAAT
CATGATATGGAGATAGAAGATGATTTTCGCGATGAGTTTATTGAGATGCAAGTAACTCTAGATGAGAGTGAGCATATATT
ATATGAATTTGCTACATTAGAGGATGTAATCAATTTATCAGAACGCTTATATAACTTAGGAGTTACTGGCGGAAAGTTGT
ACACATGGGATGGACGTTTTTATCTCTGGATGGAGGAAGAAACAAAGCTTTTAAAAGCGGATTTTATCGCGATTTTAGCG
GAGTATGGTAATCCAGCAACAGTAACGATTTACCGTATTATGGAGTATGGTAAATCGCTAATGGATTCTCAGGCGATTCA
ACAAATACATCATTATTTTATTTTAAAAGGAAACCTCAGCTAA

Upstream 100 bases:

>100_bases
TGGTTAAAAATGTCAGAATAGTTGTTCGAAAAGAACCATCTATTTCTCATTTCATATAATAAAAATTAGAAGCGATGGTT
TTACGTAAGGAGGTTATAAG

Downstream 100 bases:

>100_bases
TTAGCAATAGCTTGAGGTTTTTGTTATGACCATATTTTGATTGTTGGATAGGGTGAGATAAAGTGAAACTTTAATCAGTG
AGGTTTTTTCATCTCCCGTT

Product: adaptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEANGPVAVEVFSLQAQGMVVIVTKEN
HDMEIEDDFRDEFIEMQVTLDESEHILYEFATLEDVINLSERLYNLGVTGGKLYTWDGRFYLWMEEETKLLKADFIAILA
EYGNPATVTIYRIMEYGKSLMDSQAIQQIHHYFILKGNLS

Sequences:

>Translated_200_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEANGPVAVEVFSLQAQGMVVIVTKEN
HDMEIEDDFRDEFIEMQVTLDESEHILYEFATLEDVINLSERLYNLGVTGGKLYTWDGRFYLWMEEETKLLKADFIAILA
EYGNPATVTIYRIMEYGKSLMDSQAIQQIHHYFILKGNLS
>Mature_200_residues
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEANGPVAVEVFSLQAQGMVVIVTKEN
HDMEIEDDFRDEFIEMQVTLDESEHILYEFATLEDVINLSERLYNLGVTGGKLYTWDGRFYLWMEEETKLLKADFIAILA
EYGNPATVTIYRIMEYGKSLMDSQAIQQIHHYFILKGNLS

Specific function: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When ove

COG id: COG4862

COG function: function code OTN; Negative regulator of genetic competence, sporulation and motility

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mecA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008681 [H]

Pfam domain/function: PF05389 MecA [H]

EC number: NA

Molecular weight: Translated: 23439; Mature: 23439

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEANGPV
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKENHDMEIEDDFRDEFIEMQVTLDESEHILYEFATLEDVINLS
EEEEEEEECCCEEEEEEECCCCCCCCCHHHHCEEEEEEEECCCCEEEHHHHHHHHHHHHH
ERLYNLGVTGGKLYTWDGRFYLWMEEETKLLKADFIAILAEYGNPATVTIYRIMEYGKSL
HHHHHCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
MDSQAIQQIHHYFILKGNLS
HHHHHHHHHHHEEEEEECCC
>Mature Secondary Structure
MRLERLNYNKIKIFLTFDDLSERGLTKEDLWRNAPKVQQLFRDMMQEANKELGFEANGPV
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCE
AVEVFSLQAQGMVVIVTKENHDMEIEDDFRDEFIEMQVTLDESEHILYEFATLEDVINLS
EEEEEEEECCCEEEEEEECCCCCCCCCHHHHCEEEEEEEECCCCEEEHHHHHHHHHHHHH
ERLYNLGVTGGKLYTWDGRFYLWMEEETKLLKADFIAILAEYGNPATVTIYRIMEYGKSL
HHHHHCCCCCCEEEEECCEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHH
MDSQAIQQIHHYFILKGNLS
HHHHHHHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]