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The map label for this gene is ziaR [H]

Identifier: 152974342

GI number: 152974342

Start: 583963

End: 584340

Strand: Direct

Name: ziaR [H]

Synonym: Bcer98_0511

Alternate gene names: 152974342

Gene position: 583963-584340 (Clockwise)

Preceding gene: 152974341

Following gene: 152974343

Centisome position: 14.29

GC content: 34.92

Gene sequence:

>378_bases
ATGGCTGAAAATAAAGTAGAAACATGTCAGGATACATGTTCTCAAACAATTATCCATGAAGAAGTTGTAGATCAAGTAAA
ACAAACAATTCCAAATGATGAAAGTTTAAGTAAAGTAGCAGAATTATTTAAAGTGTTAGGTGATCGTACACGCACGCGAA
TTTTGCACGCGTTATTTGAAGCGGAGATGTGTGTGTGTGATTTAGCTTATTTACTCGGCATGACACAATCCTCTATTTCC
CATCAACTTCGTGTATTGAAACAAGCAAAACTTGTGAAAAACCGTAAAGAAGGAAAGGTTGTCTATTATTCATTAGCTGA
CCATCATGTAATCGGTATTTTTGAACAAGCATTCGAACACGTAAATGAGGAAGATTAA

Upstream 100 bases:

>100_bases
GTATCAGATTTCATTGACACATATGAATGGATGTTCATATAATAAAAGCATAAGATATATGAATGATTGTTCATATATTC
AAGTGAAGAGGTGAGCTATA

Downstream 100 bases:

>100_bases
AAAGAAAAAGCGCAAGGAGGGAGAAAAATGGCTGAGGCACTTGTGAAACGAAAACTTGTGTTGGAAGGATTGGATTGTGC
GAATTGCGCTATGAAAATCG

Product: regulatory protein ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MAENKVETCQDTCSQTIIHEEVVDQVKQTIPNDESLSKVAELFKVLGDRTRTRILHALFEAEMCVCDLAYLLGMTQSSIS
HQLRVLKQAKLVKNRKEGKVVYYSLADHHVIGIFEQAFEHVNEED

Sequences:

>Translated_125_residues
MAENKVETCQDTCSQTIIHEEVVDQVKQTIPNDESLSKVAELFKVLGDRTRTRILHALFEAEMCVCDLAYLLGMTQSSIS
HQLRVLKQAKLVKNRKEGKVVYYSLADHHVIGIFEQAFEHVNEED
>Mature_124_residues
AENKVETCQDTCSQTIIHEEVVDQVKQTIPNDESLSKVAELFKVLGDRTRTRILHALFEAEMCVCDLAYLLGMTQSSISH
QLRVLKQAKLVKNRKEGKVVYYSLADHHVIGIFEQAFEHVNEED

Specific function: Transcriptional repressor of the expression of the ziaA gene. Controls zinc homeostasis by triggering ziaA-mediated efflux of excess zinc into the periplasm [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=69, Percent_Identity=44.9275362318841, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14275; Mature: 14144

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENKVETCQDTCSQTIIHEEVVDQVKQTIPNDESLSKVAELFKVLGDRTRTRILHALFE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AEMCVCDLAYLLGMTQSSISHQLRVLKQAKLVKNRKEGKVVYYSLADHHVIGIFEQAFEH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VNEED
CCCCC
>Mature Secondary Structure 
AENKVETCQDTCSQTIIHEEVVDQVKQTIPNDESLSKVAELFKVLGDRTRTRILHALFE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
AEMCVCDLAYLLGMTQSSISHQLRVLKQAKLVKNRKEGKVVYYSLADHHVIGIFEQAFEH
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VNEED
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 9724772 [H]