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The map label for this gene is pbpX [H]

Identifier: 152974261

GI number: 152974261

Start: 482248

End: 483462

Strand: Direct

Name: pbpX [H]

Synonym: Bcer98_0428

Alternate gene names: 152974261

Gene position: 482248-483462 (Clockwise)

Preceding gene: 152974260

Following gene: 152974262

Centisome position: 11.8

GC content: 35.06

Gene sequence:

>1215_bases
ATGGAACAGGAAAAGGATAGTGTGAATCCGAAAGTTCGGAGACCAATGGTGTACATAAGAGGAATCGTGATTCTCAGTCT
AGTATTTTTAATTGTATATTTTGGATATACAAAAATAATGTCACATAGTAAAAAAGAGAATATGTTAAAAGTTGCAACGA
AGGTGAACAAGAAAGAAGAAGCATCGAAGAAAACGGAGCAACAACCAAAGCAACAAGAACAAACAGTGAAAGCGGCAGAA
CAGCCTGTTGAAGGGCCTCCGCAAGATATTAACGAAAATGCTGAGTTAGATCAGTATTTGCAAAGTAAAGGGTTTAGTGG
AACGGCAGTCGTTGTAAAGAATGGCAAAGTACTTTTGAATAAAGGATATGGCCTAGCGAATCAAGAGAAAAAAATACCAA
ATAATTCAGAAACGACATTTTATATTGGTTCAATTTCAAAAGCATTTGTAGCAACGGCGATTATGCAGTTAAAGGATCAA
AACAAACTGCAAACAGAAGATATAGTCACGAAATATATTCCTGGTTTTCCACACGGTGAGGGACTGAAGCTATCACATCT
ATTGACGCATACGTCAGGAATTCCAGAATATGAGGCAGGTAGCGAAGATATTTCTCACGAGGAATTGTTGAAAAGAATTG
GAGAACAAAAACGTTTAGCAAATCCGGGGGGGAAATGGGAGTATTCTGACTCTAATTATTCTATCCTTGCTTATATTGTT
GAAAAAGTGAGTGGACAACCGTTAGAAGAATATATTAAGCAACATATTTTCGATGTAATTGGAATGAAAAACTCAGGATT
TGGAAGAGCGTTAGAGCAAACAAGATATCCTTCCACCGGATATAAGATTGTGAATAATAATATGACAACACCTGCTATTC
CAAGTATGTCACAATTATATGGATGCGGTGATATATATACAAGTGCGTATGATTTATATTTATTTAATGAAGGACTATTT
TCTGGAAAACTCATTTCAGAAGAGAGTTATAATGAAATGTTCACACCTGTGAGAAAAAATTATGGATTTGGATGGTATGT
GAATCCAGGCAGTTATTCGAATCACGGTGTTATGCCTGGCTGGAATTGCTTAAATGGCTTTAGCAAAAGCGGAAATATAC
ATGTTGTTTTATTATCAAACATTCAAAATAATATTAAATCATTTGGCAAAGTAAATAATGATATGTATACAATGCTGCAG
CATATTGAAGTGTAA

Upstream 100 bases:

>100_bases
TGATACAGTAAGTATGGTATGAAATGGATTTTCCATTCCTTTTGAAAAAATGGGACTAATTTTTTCAAAAAATGAATAAA
ATGAGGGGAAAACAGCAGTT

Downstream 100 bases:

>100_bases
GAGGCTATCTTTGAGATAGTCTCTGTTTGTTTAGAGAGGTATTTCTTTGTATATTCAGAAGGATTATATGGATATGGGGA
TTCAGAAGCATCATGAAAGT

Product: beta-lactamase

Products: substituted beta-amino acid

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEQEKDSVNPKVRRPMVYIRGIVILSLVFLIVYFGYTKIMSHSKKENMLKVATKVNKKEEASKKTEQQPKQQEQTVKAAE
QPVEGPPQDINENAELDQYLQSKGFSGTAVVVKNGKVLLNKGYGLANQEKKIPNNSETTFYIGSISKAFVATAIMQLKDQ
NKLQTEDIVTKYIPGFPHGEGLKLSHLLTHTSGIPEYEAGSEDISHEELLKRIGEQKRLANPGGKWEYSDSNYSILAYIV
EKVSGQPLEEYIKQHIFDVIGMKNSGFGRALEQTRYPSTGYKIVNNNMTTPAIPSMSQLYGCGDIYTSAYDLYLFNEGLF
SGKLISEESYNEMFTPVRKNYGFGWYVNPGSYSNHGVMPGWNCLNGFSKSGNIHVVLLSNIQNNIKSFGKVNNDMYTMLQ
HIEV

Sequences:

>Translated_404_residues
MEQEKDSVNPKVRRPMVYIRGIVILSLVFLIVYFGYTKIMSHSKKENMLKVATKVNKKEEASKKTEQQPKQQEQTVKAAE
QPVEGPPQDINENAELDQYLQSKGFSGTAVVVKNGKVLLNKGYGLANQEKKIPNNSETTFYIGSISKAFVATAIMQLKDQ
NKLQTEDIVTKYIPGFPHGEGLKLSHLLTHTSGIPEYEAGSEDISHEELLKRIGEQKRLANPGGKWEYSDSNYSILAYIV
EKVSGQPLEEYIKQHIFDVIGMKNSGFGRALEQTRYPSTGYKIVNNNMTTPAIPSMSQLYGCGDIYTSAYDLYLFNEGLF
SGKLISEESYNEMFTPVRKNYGFGWYVNPGSYSNHGVMPGWNCLNGFSKSGNIHVVLLSNIQNNIKSFGKVNNDMYTMLQ
HIEV
>Mature_404_residues
MEQEKDSVNPKVRRPMVYIRGIVILSLVFLIVYFGYTKIMSHSKKENMLKVATKVNKKEEASKKTEQQPKQQEQTVKAAE
QPVEGPPQDINENAELDQYLQSKGFSGTAVVVKNGKVLLNKGYGLANQEKKIPNNSETTFYIGSISKAFVATAIMQLKDQ
NKLQTEDIVTKYIPGFPHGEGLKLSHLLTHTSGIPEYEAGSEDISHEELLKRIGEQKRLANPGGKWEYSDSNYSILAYIV
EKVSGQPLEEYIKQHIFDVIGMKNSGFGRALEQTRYPSTGYKIVNNNMTTPAIPSMSQLYGCGDIYTSAYDLYLFNEGLF
SGKLISEESYNEMFTPVRKNYGFGWYVNPGSYSNHGVMPGWNCLNGFSKSGNIHVVLLSNIQNNIKSFGKVNNDMYTMLQ
HIEV

Specific function: Unknown

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential). Note=Localizes to the division septum during vegetative growth, and accumulates at the prespore during sporulation [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=340, Percent_Identity=25, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786574, Length=251, Percent_Identity=24.3027888446215, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI115533026, Length=359, Percent_Identity=21.7270194986072, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17565630, Length=314, Percent_Identity=25.4777070063694, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6

Molecular weight: Translated: 45424; Mature: 45424

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQEKDSVNPKVRRPMVYIRGIVILSLVFLIVYFGYTKIMSHSKKENMLKVATKVNKKEE
CCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ASKKTEQQPKQQEQTVKAAEQPVEGPPQDINENAELDQYLQSKGFSGTAVVVKNGKVLLN
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCEEEEE
KGYGLANQEKKIPNNSETTFYIGSISKAFVATAIMQLKDQNKLQTEDIVTKYIPGFPHGE
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
GLKLSHLLTHTSGIPEYEAGSEDISHEELLKRIGEQKRLANPGGKWEYSDSNYSILAYIV
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHH
EKVSGQPLEEYIKQHIFDVIGMKNSGFGRALEQTRYPSTGYKIVNNNMTTPAIPSMSQLY
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHH
GCGDIYTSAYDLYLFNEGLFSGKLISEESYNEMFTPVRKNYGFGWYVNPGSYSNHGVMPG
CCHHHHHHHEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
WNCLNGFSKSGNIHVVLLSNIQNNIKSFGKVNNDMYTMLQHIEV
CHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MEQEKDSVNPKVRRPMVYIRGIVILSLVFLIVYFGYTKIMSHSKKENMLKVATKVNKKEE
CCCCCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
ASKKTEQQPKQQEQTVKAAEQPVEGPPQDINENAELDQYLQSKGFSGTAVVVKNGKVLLN
HHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCEEEEE
KGYGLANQEKKIPNNSETTFYIGSISKAFVATAIMQLKDQNKLQTEDIVTKYIPGFPHGE
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
GLKLSHLLTHTSGIPEYEAGSEDISHEELLKRIGEQKRLANPGGKWEYSDSNYSILAYIV
CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHH
EKVSGQPLEEYIKQHIFDVIGMKNSGFGRALEQTRYPSTGYKIVNNNMTTPAIPSMSQLY
HHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHH
GCGDIYTSAYDLYLFNEGLFSGKLISEESYNEMFTPVRKNYGFGWYVNPGSYSNHGVMPG
CCHHHHHHHEEEEEECCCCCCCEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
WNCLNGFSKSGNIHVVLLSNIQNNIKSFGKVNNDMYTMLQHIEV
CHHHHCCCCCCCEEEEEHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: beta-lactam; H2O

Specific reaction: A beta-lactam + H2O = a substituted beta-amino acid

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]