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The map label for this gene is yrpG [H]

Identifier: 150398680

GI number: 150398680

Start: 3700997

End: 3701947

Strand: Reverse

Name: yrpG [H]

Synonym: Smed_3494

Alternate gene names: 150398680

Gene position: 3701947-3700997 (Counterclockwise)

Preceding gene: 150398682

Following gene: 150398677

Centisome position: 97.89

GC content: 61.41

Gene sequence:

>951_bases
ATGGAAATGCGCAGACTTGGCCGTACAGGTCTTTCGATTGCCCCGCTGGTCTTCGGCGGCAATGTCTTCGGCTGGACCGC
GGATGAGAAAACCTCCTTCGCGCTTCTCGACGCCTTCTTCGATGCCGGTTTCAATGCCATCGACACGGCCGACGTCTATT
CCTCCTGGGTGCCGGGCAACAGCGGCGGCGAATCGGAGGCGGTCATCGGCAGATGGTTGAAACAATCGGGACGCCCGCGC
GATAGCGCCGTCATCGTCACCAAGGTCGGCTCGGAACTCGGACCGGAACGCAAGGGTCTCTCGCGGCGCTGGATCATGCA
GGCGGTCGAGGATTCACTGAGGCGCCTGAAGACCGACTATATCGATCTCTACCTGTCACATTGGCCGGACCCCGACACGC
CATACGAGGAGACGCTCGCCGCCTACGACACGCTTCGCTCGCAGGGCAAGGTGCGGGCGATAGGCGCCTCCAATCTCGAT
GCAGAGCAGATGCGCGACGCACTCCAGGTCGCGGCAGCGAAGGACCTGCCCCGCTACGACGTGCTGCAGCCCGAGTACAA
TCTCTATGATCGCGCTTCCTACGACGGCGCTCTGCGCAACCTCTGCATCGAAGAGGAGATCGGCGTCATCACCTATTTCA
GTCTTGCGAGAGGCTTTCTTTCCGGCAAGTACCGCTCGCACAAGGATCTGGAGGGCTCCGCTCGCGGCGGCGGCGTCGAA
AAATATCTCGATGGGCGCGGCATGCGTATCCTTGGAGTGCTGGATGAAATCGCCGGGGAAACCGGCGCGAAGCAGGCTGA
AATTGCGCTCGCCTGGATCATCGCCCGCGAAGGCGTCACAGCACCGATTGCCAGCGCCACCAACCTCGACCAACTGGGAA
GCCTTGTAAGGTCTGCGGAGATCAAGCTTTCCGGCGAAGCGATAAGACGGCTGAACGAGGTGAGCGAATAG

Upstream 100 bases:

>100_bases
ACCGCGGACGAAGGTGTCTTTCGACCGGAAGCTGGCCTATGTTTTTGCCGCAACCCTCCCGATCGCAGCTCGTCTTCATC
CAACCACATGGAGTGAAACC

Downstream 100 bases:

>100_bases
AAGGCGTGGAGGACGTCACCACCAGTCCACCTTCACAAGCGCCGGGAACCCCGGGTAAAGCTGCGCATGACTGCCTTCGT
GGTTGGCCATGCCGGGCTTC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MEMRRLGRTGLSIAPLVFGGNVFGWTADEKTSFALLDAFFDAGFNAIDTADVYSSWVPGNSGGESEAVIGRWLKQSGRPR
DSAVIVTKVGSELGPERKGLSRRWIMQAVEDSLRRLKTDYIDLYLSHWPDPDTPYEETLAAYDTLRSQGKVRAIGASNLD
AEQMRDALQVAAAKDLPRYDVLQPEYNLYDRASYDGALRNLCIEEEIGVITYFSLARGFLSGKYRSHKDLEGSARGGGVE
KYLDGRGMRILGVLDEIAGETGAKQAEIALAWIIAREGVTAPIASATNLDQLGSLVRSAEIKLSGEAIRRLNEVSE

Sequences:

>Translated_316_residues
MEMRRLGRTGLSIAPLVFGGNVFGWTADEKTSFALLDAFFDAGFNAIDTADVYSSWVPGNSGGESEAVIGRWLKQSGRPR
DSAVIVTKVGSELGPERKGLSRRWIMQAVEDSLRRLKTDYIDLYLSHWPDPDTPYEETLAAYDTLRSQGKVRAIGASNLD
AEQMRDALQVAAAKDLPRYDVLQPEYNLYDRASYDGALRNLCIEEEIGVITYFSLARGFLSGKYRSHKDLEGSARGGGVE
KYLDGRGMRILGVLDEIAGETGAKQAEIALAWIIAREGVTAPIASATNLDQLGSLVRSAEIKLSGEAIRRLNEVSE
>Mature_316_residues
MEMRRLGRTGLSIAPLVFGGNVFGWTADEKTSFALLDAFFDAGFNAIDTADVYSSWVPGNSGGESEAVIGRWLKQSGRPR
DSAVIVTKVGSELGPERKGLSRRWIMQAVEDSLRRLKTDYIDLYLSHWPDPDTPYEETLAAYDTLRSQGKVRAIGASNLD
AEQMRDALQVAAAKDLPRYDVLQPEYNLYDRASYDGALRNLCIEEEIGVITYFSLARGFLSGKYRSHKDLEGSARGGGVE
KYLDGRGMRILGVLDEIAGETGAKQAEIALAWIIAREGVTAPIASATNLDQLGSLVRSAEIKLSGEAIRRLNEVSE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=32.2085889570552, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI4504825, Length=323, Percent_Identity=32.1981424148607, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI27436964, Length=303, Percent_Identity=30.6930693069307, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI27436966, Length=303, Percent_Identity=30.6930693069307, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI27436962, Length=303, Percent_Identity=30.6930693069307, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI27436971, Length=306, Percent_Identity=29.7385620915033, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI223718702, Length=212, Percent_Identity=30.6603773584906, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI41152114, Length=212, Percent_Identity=31.6037735849057, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI223718708, Length=149, Percent_Identity=33.5570469798658, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=33.75, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=28.9398280802292, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789375, Length=304, Percent_Identity=29.9342105263158, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788070, Length=343, Percent_Identity=31.1953352769679, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788081, Length=285, Percent_Identity=31.5789473684211, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786400, Length=269, Percent_Identity=27.5092936802974, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994888, Length=149, Percent_Identity=29.5302013422819, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082198, Length=142, Percent_Identity=27.4647887323944, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323998, Length=340, Percent_Identity=28.8235294117647, Blast_Score=109, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=26.3313609467456, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=310, Percent_Identity=28.0645161290323, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319951, Length=340, Percent_Identity=25.8823529411765, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=165, Percent_Identity=34.5454545454545, Blast_Score=79, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323684, Length=158, Percent_Identity=34.8101265822785, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322615, Length=259, Percent_Identity=25.0965250965251, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320576, Length=197, Percent_Identity=28.4263959390863, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=24.0579710144928, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45549126, Length=342, Percent_Identity=24.2690058479532, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24644950, Length=316, Percent_Identity=26.2658227848101, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646155, Length=182, Percent_Identity=32.4175824175824, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34645; Mature: 34645

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMRRLGRTGLSIAPLVFGGNVFGWTADEKTSFALLDAFFDAGFNAIDTADVYSSWVPGN
CCHHHHCCCCCEEEHEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
SGGESEAVIGRWLKQSGRPRDSAVIVTKVGSELGPERKGLSRRWIMQAVEDSLRRLKTDY
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHH
IDLYLSHWPDPDTPYEETLAAYDTLRSQGKVRAIGASNLDAEQMRDALQVAAAKDLPRYD
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
VLQPEYNLYDRASYDGALRNLCIEEEIGVITYFSLARGFLSGKYRSHKDLEGSARGGGVE
CCCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
KYLDGRGMRILGVLDEIAGETGAKQAEIALAWIIAREGVTAPIASATNLDQLGSLVRSAE
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHH
IKLSGEAIRRLNEVSE
EEECHHHHHHHHHHCC
>Mature Secondary Structure
MEMRRLGRTGLSIAPLVFGGNVFGWTADEKTSFALLDAFFDAGFNAIDTADVYSSWVPGN
CCHHHHCCCCCEEEHEEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCC
SGGESEAVIGRWLKQSGRPRDSAVIVTKVGSELGPERKGLSRRWIMQAVEDSLRRLKTDY
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHCHHHHHHHHHHHHHHHHHHHHH
IDLYLSHWPDPDTPYEETLAAYDTLRSQGKVRAIGASNLDAEQMRDALQVAAAKDLPRYD
HHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
VLQPEYNLYDRASYDGALRNLCIEEEIGVITYFSLARGFLSGKYRSHKDLEGSARGGGVE
CCCCCCCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHH
KYLDGRGMRILGVLDEIAGETGAKQAEIALAWIIAREGVTAPIASATNLDQLGSLVRSAE
HHHCCCCCCHHHHHHHHCCCCCCCHHHHHEEEEEHHCCCCCCCCCCCCHHHHHHHHHHHH
IKLSGEAIRRLNEVSE
EEECHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9308178; 9384377 [H]