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The map label for this gene is coaA [H]

Identifier: 150398449

GI number: 150398449

Start: 3438155

End: 3439150

Strand: Reverse

Name: coaA [H]

Synonym: Smed_3257

Alternate gene names: 150398449

Gene position: 3439150-3438155 (Counterclockwise)

Preceding gene: 150398450

Following gene: 150398444

Centisome position: 90.94

GC content: 61.35

Gene sequence:

>996_bases
ATGAGCATCGCCGCGAAAGACATCGAACCGGCCGACATTCCGGGCAATCTTCAGGGGGGCGAATATTCGCCCTATCACGT
CTTCTCCGCGGAGGAATGGTCGCGCTTTCGCGCCGATACGCCGCTGACGCTGACTGCCGACGAGGTGCAGCGCCTCCGCT
CGCTCAACGACCCGGTCGATCTCGACGAAGTGCGCCGGATCTACCTCTCGCTGTCGCGGCTCCTCTCGGCCCATGTGGAG
GCGTCGCAGATTCTCTTCCGGCAGCGGACGCGCTTCCTCAGCATGTCGAACGAGACGAAAACGCCGTTCGTCATAGGCGT
CGCCGGCTCCGTCGCCGTCGGCAAATCGACGACGGCGCGCATTCTTGCAGAGCTTCTTGCACGCTGGCCCTCCAGCCCGA
AGGTCGACCTCGTCACCACCGACGGCTTCCTCTATCCGAACGCCGTTTTGCAGCGGGAAAGCCTGATGGATCGCAAGGGC
TTCCCCGAGAGCTACGATATCGGTGCGCTGCTCAGATTCCTTTCCGCGATCAAAGCCGGACGGCCGAACGTCAAGGCTCC
GACCTATTCGCACCTGACCTACGACGTGATCCCCGACCAGTTCCAGCTGGTCGACCGGCCGGACATCCTGGTTTTCGAGG
GAATAAACGTCCTGCAGTCGCGCGATCTGCCGGCCGATGGAAAGATCGTGCCGATGGTCTCGGATTTCTTCGACTTCTCG
ATCTATATCGACGCTGAGGAAAGCCTCATCCATAGCTGGTATGTGAACCGCTTCATGAGGCTGCGCGAAACGGCGTTCCA
GAATCCGCAGTCCTTCTTCCATCGCTATGCGACGATCAGCGAGGATGCGGCCCGGGCGATCGCCGAGGGCCTGTGGCACA
ACATCAACCTCAAGAACCTGCACCAGAACATTCTGCCGACGCGGCCGCGCGCCGATCTCATCCTGCAGAAGGGCCCAAGT
CACCTGACGCAGACCGTGGCTCTCAGGAAGCTTTAG

Upstream 100 bases:

>100_bases
TATTGAATATCGCCGCCATCCCGTTACAGGATGTGATGAGCGAACTGGCCAGGCGGACGAGCCAGTCCGGCCTGCAGGAA
AAGGCGAACCGGCAGAATCC

Downstream 100 bases:

>100_bases
AGCGGGATGAGGAAAAGTGCGCGCGGTTTGTCCGCCCGCATTCCGCTCTATCTTAGTTGAAGGTTGATTCGACCTAAAAA
AATCATGATCCGAGCCGAAT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVDLDEVRRIYLSLSRLLSAHVE
ASQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTARILAELLARWPSSPKVDLVTTDGFLYPNAVLQRESLMDRKG
FPESYDIGALLRFLSAIKAGRPNVKAPTYSHLTYDVIPDQFQLVDRPDILVFEGINVLQSRDLPADGKIVPMVSDFFDFS
IYIDAEESLIHSWYVNRFMRLRETAFQNPQSFFHRYATISEDAARAIAEGLWHNINLKNLHQNILPTRPRADLILQKGPS
HLTQTVALRKL

Sequences:

>Translated_331_residues
MSIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVDLDEVRRIYLSLSRLLSAHVE
ASQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTARILAELLARWPSSPKVDLVTTDGFLYPNAVLQRESLMDRKG
FPESYDIGALLRFLSAIKAGRPNVKAPTYSHLTYDVIPDQFQLVDRPDILVFEGINVLQSRDLPADGKIVPMVSDFFDFS
IYIDAEESLIHSWYVNRFMRLRETAFQNPQSFFHRYATISEDAARAIAEGLWHNINLKNLHQNILPTRPRADLILQKGPS
HLTQTVALRKL
>Mature_330_residues
SIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVDLDEVRRIYLSLSRLLSAHVEA
SQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTARILAELLARWPSSPKVDLVTTDGFLYPNAVLQRESLMDRKGF
PESYDIGALLRFLSAIKAGRPNVKAPTYSHLTYDVIPDQFQLVDRPDILVFEGINVLQSRDLPADGKIVPMVSDFFDFSI
YIDAEESLIHSWYVNRFMRLRETAFQNPQSFFHRYATISEDAARAIAEGLWHNINLKNLHQNILPTRPRADLILQKGPSH
LTQTVALRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=52.411575562701, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 37442; Mature: 37311

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVD
CCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCC
LDEVRRIYLSLSRLLSAHVEASQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCHHHH
ILAELLARWPSSPKVDLVTTDGFLYPNAVLQRESLMDRKGFPESYDIGALLRFLSAIKAG
HHHHHHHHCCCCCCEEEEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
RPNVKAPTYSHLTYDVIPDQFQLVDRPDILVFEGINVLQSRDLPADGKIVPMVSDFFDFS
CCCCCCCCCCCEEEECCCCHHEECCCCCEEEECCCHHHHCCCCCCCCEEEEEECCCCCEE
IYIDAEESLIHSWYVNRFMRLRETAFQNPQSFFHRYATISEDAARAIAEGLWHNINLKNL
EEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHH
HQNILPTRPRADLILQKGPSHLTQTVALRKL
HHHHCCCCCCHHHEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SIAAKDIEPADIPGNLQGGEYSPYHVFSAEEWSRFRADTPLTLTADEVQRLRSLNDPVD
CCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCC
LDEVRRIYLSLSRLLSAHVEASQILFRQRTRFLSMSNETKTPFVIGVAGSVAVGKSTTAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEECCCHHHH
ILAELLARWPSSPKVDLVTTDGFLYPNAVLQRESLMDRKGFPESYDIGALLRFLSAIKAG
HHHHHHHHCCCCCCEEEEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
RPNVKAPTYSHLTYDVIPDQFQLVDRPDILVFEGINVLQSRDLPADGKIVPMVSDFFDFS
CCCCCCCCCCCEEEECCCCHHEECCCCCEEEECCCHHHHCCCCCCCCEEEEEECCCCCEE
IYIDAEESLIHSWYVNRFMRLRETAFQNPQSFFHRYATISEDAARAIAEGLWHNINLKNL
EEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHH
HQNILPTRPRADLILQKGPSHLTQTVALRKL
HHHHCCCCCCHHHEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]