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The map label for this gene is glpD [H]

Identifier: 150398101

GI number: 150398101

Start: 3046392

End: 3047903

Strand: Direct

Name: glpD [H]

Synonym: Smed_2903

Alternate gene names: 150398101

Gene position: 3046392-3047903 (Clockwise)

Preceding gene: 150398100

Following gene: 150398102

Centisome position: 80.55

GC content: 62.3

Gene sequence:

>1512_bases
GTGTCAGAGCAGGCGATCTTCGACGTCTTCGTCATAGGCGGCGGCATCAACGGATGCGGCATTGCGCGTGATGCGGCCGG
TCGGGGATATTCCGTCGCGCTTGCGGAGATGAACGATTTCGCCTCGGGAACGTCTTCCGGCTCGACCAAGCTCATCCATG
GCGGCCTGCGCTATCTCGAATATTATGAGTTCCGCCTCGTACGCGAAGCCTTGATGGAGCGCGAAGTCCTCTGGGCGATG
GCGCCGCATGTCATTTGGCCGATGCGGTTCGTTCTGCCTTTCCACAAGGGCGGCCCACGGCCCGCCTGGCTGATCCGTCT
CGGCCTCTTCCTCTACGACCATATTGGCGGCCGCAAGCGCCTGCCGGCGACAAGCACTCTTGACTTGACCCGGGATCCGG
CCGGCGTGCCCTTGAAGCGCCTCTTCTCCAAGGCTTTCGAATATTCGGATGGGTGGGTCGACGATGCCCGCCTCGTGGTC
TTGAACGCACGCGATGCCGCCGATCGCGGCGCGCGGATCATGGCCCGTACCCGCGTCGTCTCAGCACGGCGCGCATCCGG
ACGTTGGACGATAGAGATCGAGGATGTCACGACGGGAGCGCGCGAGACGCTGGGCGCCCGCATGCTCGTCAATGCCGCAG
GTCCCTGGGTGGACCGGATTCTCTCCGAAGCCGTCGGAAAGAAGGACGTCCGCAATGTCCGCCTCGTCCAGGGCAGCCAT
ATCGTCTTAACGAAAAAGTTCGACGATACGCGGGCCTATTTCTTCCAGAACCCGGACGGGCGGATCATGTTCGCCATTCC
CTACCAGAACGATTTCACACTCATCGGAACGACAGATCACGATTTTGCCGGCAATCCGGCGGATGTGCGCATCAGTGACG
CAGAAATCGACTATCTCTGCGCGGCGGCGAGCGAATATTTCAAAGATCCGGTCACGAGGGACGATATCGTCTGGACCTAT
TCCGCCGTTCGTCCCCTTTACGACGACGGCGCGAGTAAAGCCCAGGAAGCGACCCGCGACTATGTGCTGCGCGTCGAGAA
CGGCGATGCGCCGCTGCTCAATGTCTTCGGCGGCAAGCTCACCACCTACCGGCGGCTTGCGGAATCGGCTCTGGACAAGA
TCGGCGAGGCTATTGGCGCCAAGGGCGGGAAATGGACCGCCGGATCGCATCTTCCCGGCGGCGACTTCCCGGCGACAGGC
TATGAAGACGAGGTGGAAAAGCTCAAGTCGCGCTATCCGTTTCTGGCTGCCTCGCATGTCCGCCGGCTGGTGCGGCTCTA
TGGGAGGCTTGCGGCGCAGCTTCTCGGCAACGCCGCAAGCGAGGCCGATCTTGGAAGGTACTTCGGAGCGGATCTCTACG
CGGCGGAGGTGGATTGGCTCATCGGACGGGAATGGGCGTTGGGCGCGGAAGACGTGCTTTGGCGCCGAACGAAACTGGGA
CTGAAGTTTTCGCGGGCGCAAATCGCGGAACTGGAGGAATATATCCGGGCAGCGGCCAACGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
GCCCAAACATTCGTTTGACATTCGAAATATTTTCGCTTTAACTGTTTTCACTTTCGCGATTGCGTGGAATTGTGCGTTGC
GAAAAGTGGAGGGGAACAGA

Downstream 100 bases:

>100_bases
GATACCACGGCTGAACCGCCGGTGGCTGGGTGGAGAATTCAATGCTTGAAATGAAGAACATATCCAAGGTCGTGGGGGGC
GAGATGCACATCCACCCGAC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MSEQAIFDVFVIGGGINGCGIARDAAGRGYSVALAEMNDFASGTSSGSTKLIHGGLRYLEYYEFRLVREALMEREVLWAM
APHVIWPMRFVLPFHKGGPRPAWLIRLGLFLYDHIGGRKRLPATSTLDLTRDPAGVPLKRLFSKAFEYSDGWVDDARLVV
LNARDAADRGARIMARTRVVSARRASGRWTIEIEDVTTGARETLGARMLVNAAGPWVDRILSEAVGKKDVRNVRLVQGSH
IVLTKKFDDTRAYFFQNPDGRIMFAIPYQNDFTLIGTTDHDFAGNPADVRISDAEIDYLCAAASEYFKDPVTRDDIVWTY
SAVRPLYDDGASKAQEATRDYVLRVENGDAPLLNVFGGKLTTYRRLAESALDKIGEAIGAKGGKWTAGSHLPGGDFPATG
YEDEVEKLKSRYPFLAASHVRRLVRLYGRLAAQLLGNAASEADLGRYFGADLYAAEVDWLIGREWALGAEDVLWRRTKLG
LKFSRAQIAELEEYIRAAANAAA

Sequences:

>Translated_503_residues
MSEQAIFDVFVIGGGINGCGIARDAAGRGYSVALAEMNDFASGTSSGSTKLIHGGLRYLEYYEFRLVREALMEREVLWAM
APHVIWPMRFVLPFHKGGPRPAWLIRLGLFLYDHIGGRKRLPATSTLDLTRDPAGVPLKRLFSKAFEYSDGWVDDARLVV
LNARDAADRGARIMARTRVVSARRASGRWTIEIEDVTTGARETLGARMLVNAAGPWVDRILSEAVGKKDVRNVRLVQGSH
IVLTKKFDDTRAYFFQNPDGRIMFAIPYQNDFTLIGTTDHDFAGNPADVRISDAEIDYLCAAASEYFKDPVTRDDIVWTY
SAVRPLYDDGASKAQEATRDYVLRVENGDAPLLNVFGGKLTTYRRLAESALDKIGEAIGAKGGKWTAGSHLPGGDFPATG
YEDEVEKLKSRYPFLAASHVRRLVRLYGRLAAQLLGNAASEADLGRYFGADLYAAEVDWLIGREWALGAEDVLWRRTKLG
LKFSRAQIAELEEYIRAAANAAA
>Mature_502_residues
SEQAIFDVFVIGGGINGCGIARDAAGRGYSVALAEMNDFASGTSSGSTKLIHGGLRYLEYYEFRLVREALMEREVLWAMA
PHVIWPMRFVLPFHKGGPRPAWLIRLGLFLYDHIGGRKRLPATSTLDLTRDPAGVPLKRLFSKAFEYSDGWVDDARLVVL
NARDAADRGARIMARTRVVSARRASGRWTIEIEDVTTGARETLGARMLVNAAGPWVDRILSEAVGKKDVRNVRLVQGSHI
VLTKKFDDTRAYFFQNPDGRIMFAIPYQNDFTLIGTTDHDFAGNPADVRISDAEIDYLCAAASEYFKDPVTRDDIVWTYS
AVRPLYDDGASKAQEATRDYVLRVENGDAPLLNVFGGKLTTYRRLAESALDKIGEAIGAKGGKWTAGSHLPGGDFPATGY
EDEVEKLKSRYPFLAASHVRRLVRLYGRLAAQLLGNAASEADLGRYFGADLYAAEVDWLIGREWALGAEDVLWRRTKLGL
KFSRAQIAELEEYIRAAANAAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=518, Percent_Identity=32.4324324324324, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI285002231, Length=518, Percent_Identity=32.4324324324324, Blast_Score=188, Evalue=8e-48,
Organism=Escherichia coli, GI2367226, Length=467, Percent_Identity=49.0364025695931, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1788574, Length=393, Percent_Identity=28.498727735369, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17509253, Length=540, Percent_Identity=30.3703703703704, Blast_Score=164, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI115534726, Length=510, Percent_Identity=29.2156862745098, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=419, Percent_Identity=33.1742243436754, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI161077125, Length=401, Percent_Identity=32.4189526184539, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24653942, Length=401, Percent_Identity=32.4189526184539, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24653944, Length=401, Percent_Identity=32.4189526184539, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI20130025, Length=401, Percent_Identity=32.4189526184539, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24586295, Length=524, Percent_Identity=27.4809160305344, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI19921278, Length=535, Percent_Identity=24.2990654205607, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55671; Mature: 55540

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQAIFDVFVIGGGINGCGIARDAAGRGYSVALAEMNDFASGTSSGSTKLIHGGLRYLE
CCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCEEEHHHHHHHH
YYEFRLVREALMEREVLWAMAPHVIWPMRFVLPFHKGGPRPAWLIRLGLFLYDHIGGRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATSTLDLTRDPAGVPLKRLFSKAFEYSDGWVDDARLVVLNARDAADRGARIMARTRVV
CCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SARRASGRWTIEIEDVTTGARETLGARMLVNAAGPWVDRILSEAVGKKDVRNVRLVQGSH
HHHCCCCEEEEEEECCCCCHHHHHCCEEEEECCCHHHHHHHHHHHCCHHCCCEEEEECCE
IVLTKKFDDTRAYFFQNPDGRIMFAIPYQNDFTLIGTTDHDFAGNPADVRISDAEIDYLC
EEEEECCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCHHHHH
AAASEYFKDPVTRDDIVWTYSAVRPLYDDGASKAQEATRDYVLRVENGDAPLLNVFGGKL
HHHHHHHCCCCCCCCEEEEHHHHCHHHCCCHHHHHHHHHHEEEEEECCCCCEEECCCCHH
TTYRRLAESALDKIGEAIGAKGGKWTAGSHLPGGDFPATGYEDEVEKLKSRYPFLAASHV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHH
RRLVRLYGRLAAQLLGNAASEADLGRYFGADLYAAEVDWLIGREWALGAEDVLWRRTKLG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCC
LKFSRAQIAELEEYIRAAANAAA
CEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEQAIFDVFVIGGGINGCGIARDAAGRGYSVALAEMNDFASGTSSGSTKLIHGGLRYLE
CCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCEEEHHHHHHHH
YYEFRLVREALMEREVLWAMAPHVIWPMRFVLPFHKGGPRPAWLIRLGLFLYDHIGGRKR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATSTLDLTRDPAGVPLKRLFSKAFEYSDGWVDDARLVVLNARDAADRGARIMARTRVV
CCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHH
SARRASGRWTIEIEDVTTGARETLGARMLVNAAGPWVDRILSEAVGKKDVRNVRLVQGSH
HHHCCCCEEEEEEECCCCCHHHHHCCEEEEECCCHHHHHHHHHHHCCHHCCCEEEEECCE
IVLTKKFDDTRAYFFQNPDGRIMFAIPYQNDFTLIGTTDHDFAGNPADVRISDAEIDYLC
EEEEECCCCCEEEEEECCCCCEEEEEECCCCEEEEECCCCCCCCCCCCEEEECCCHHHHH
AAASEYFKDPVTRDDIVWTYSAVRPLYDDGASKAQEATRDYVLRVENGDAPLLNVFGGKL
HHHHHHHCCCCCCCCEEEEHHHHCHHHCCCHHHHHHHHHHEEEEEECCCCCEEECCCCHH
TTYRRLAESALDKIGEAIGAKGGKWTAGSHLPGGDFPATGYEDEVEKLKSRYPFLAASHV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHH
RRLVRLYGRLAAQLLGNAASEADLGRYFGADLYAAEVDWLIGREWALGAEDVLWRRTKLG
HHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCC
LKFSRAQIAELEEYIRAAANAAA
CEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]